• Title/Summary/Keyword: H1-A1, and H1-A2

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Synthesis and Antibacterial Activity of New Tetrazole Derivatives (새로운 Tetrazole유도체의 합성과 항균활성)

  • Mulwad, V.V.;Pawar, Rupesh B;Chaskar, Atul C
    • Journal of the Korean Chemical Society
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    • v.52 no.3
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    • pp.249-256
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    • 2008
  • 3-Acetyl/Formyl 4-hydroxy-2H(1)-benzopyran-2-one on treatment with malonitrile and ethyl cyanoacetate yielded 1,1-dicyano-2-[4/-hydroxy-2/H(1)-benzopyran-2/-one-3/-yl] ethene/propene 2a-h and ethyl-2-cyano-3-[4/-hydroxy-2/H (1)-benzopyran-2/-one-3/-yl] propenoate/butenoate 3a-h respectively. The 1,3 dipolar reaction of 2a-h with NaN3 gave the tetrazole derivative 4a-h. 3a-h on cyclization with PPA gave 3-cyano-2H,5H-pyrano [3, 2-c] benzopyran-2,5-diones 5a-h which on 1,3 dipolar reaction with NaN3 to gave 3-(1/H-tetrazol-5/-yl)-2H,5H-pyrano[3, 2-c] benzopyran-2,5-diones 6a-h. The structures of the compounds have been established on the basis of the spectral and analytical data. All the compounds were screened for their antimicrobial activities and have been found to exhibited significant antibacterial activities. Compounds 2h and 4h showed the activity 50g/mL.

Tonal development and voice quality in the stops of Seoul Korean

  • Yu, Hye Jeong
    • Phonetics and Speech Sciences
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    • v.10 no.4
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    • pp.91-99
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    • 2018
  • Korean stops are currently undergoing a tonogenetic sound change, as found in the Seoul dialect in which a merged VOT of aspirated and lax stops induces F0 to be the primary cue for distinguishing the two stops and the lax stops have lower F0 than the aspirated stops. In tonal languages, low tone is produced with a breathy voice. This study investigated whether there are changes in voice quality with respect to the tonogenetic sound change of Korean stops. Two age groups speaking the Seoul dialect participated in this study: five females and six males born in the 1940s and 1950s and nine females and eight males born in the 1980s and 1990s. This study replicated previous findings of VOT and F0 and further examined H1-H2, H1-A1, and H1-A2 to see how they correlate with the sound change. In the older and younger generations, H1-H2, H1-A1, and H1-A2 were significantly lower after the tense stops than after the aspirated and lax stops, but they were not significantly different after the aspirated and lax stops. However, the younger females exhibited some different results for H1-H2 and H1-A2 than the older generation. In the younger females, the H1-H2 mean was higher after the aspirated stops than it was after the lax stops at the vowel onset, and the H1-H2 difference increased at the vowel midpoint. Although there was an inter-speaker variation in the results of H1-H2 and H1-A1, analyses of individual speakers showed that the H1-H2 and H1-A1 were higher after the lax stops than after the aspirated stops in the younger female speakers. These results indicate that lax stops tend to be breathier than aspirated stops in the younger female speakers. They also indicate that changes in voice quality are on Korean stops with tonal sound change, but are still developing.

GORENSTEIN SEQUENCES OF HIGH SOCLE DEGREES

  • Park, Jung Pil;Shin, Yong-Su
    • Journal of the Korean Mathematical Society
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    • v.59 no.1
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    • pp.71-85
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    • 2022
  • In [4], the authors showed that if an h-vector (h0, h1, …, he) with h1 = 4e - 4 and hi ≤ h1 is a Gorenstein sequence, then h1 = hi for every 1 ≤ i ≤ e - 1 and e ≥ 6. In this paper, we show that if an h-vector (h0, h1, …, he) with h1 = 4e - 4, h2 = 4e - 3, and hi ≤ h2 is a Gorenstein sequence, then h2 = hi for every 2 ≤ i ≤ e - 2 and e ≥ 7. We also propose an open question that if an h-vector (h0, h1, …, he) with h1 = 4e - 4, 4e - 3 < h2 ≤ (h1)(1)|+1+1, and h2 ≤ hi is a Gorenstein sequence, then h2 = hi for every 2 ≤ i ≤ e - 2 and e ≥ 6.

Perceptual cues for /o/ and /u/ in Seoul Korean (서울말 /?/와 /?/의 지각특성)

  • Byun, Hi-Gyung
    • Phonetics and Speech Sciences
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    • v.12 no.3
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    • pp.1-14
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    • 2020
  • Previous studies have confirmed that /o/ and /u/ in Seoul Korean are undergoing a merger in the F1/F2 space, especially for female speakers. As a substitute parameter for formants, it is reported that female speakers use phonation (H1-H2) differences to distinguish /o/ from /u/. This study aimed to explore whether H1-H2 values are being used as perceptual cues for /o/-/u/. A perception test was conducted with 35 college students using /o/ and /u/ spoken by 41 females, which overlap considerably in the vowel space. An acoustic analysis of 182 stimuli was also conducted to see if there is any correspondence between production and perception. The identification rate was 89% on average, 86% for /o/, and 91% for /u/. The results confirmed that when /o/ and /u/ cannot be distinguished in the F1/F2 space because they are too close, H1-H2 differences contribute significantly to the separation of the two vowels. However, in perception, this was not the case. H1-H2 values were not significantly involved in the identification process, and the formants (especially F2) were still dominant cues. The study also showed that even though H1-H2 differences are apparent in females' production, males do not use H1-H2 in their production, and both females and males do not use H1-H2 in their perception. It is presumed that H1-H2 has not yet been developed as a perceptual cue for /o/ and /u/.

A Study on Improvement of Gesture Function according to the Sleeve's Height and Existence of Elastic - Focused on Female High School Student's Summer Blouses - (소매산의 높이와 신축성 유무에 따른 동작기능성에 관한 연구 - 여고생 여름 교복 블라우스를 중심으로 -)

  • Park, Kil-Soon;Ryu, Sin-A
    • The Research Journal of the Costume Culture
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    • v.17 no.6
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    • pp.992-1008
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    • 2009
  • This study is to present a female high school summer blouse with high movement functionality and satisfying appearance. For the experimental research 6 subjects with closest average body shapes and their body surface was measured at beginning and after selecting a representative movement the tested uniform was worn and the appearance and movement functionality was evaluated. The results of this research are as follows. In the research with the aims to improve the sleeve designed the height in 3 types as A.H/4+3, A.H/4+2, A.H/4+1 and their evaluation showed that in the order of best appearance was A.H/4+2, A.H/4+1, A.H/4+3. In the order of best comfort was A.H/4+2, A.H/4+3, A.H/4+1 and the best order for movement functionality was A.H/4+1, A.H/4+2, A.H/4+3. Additional height types designed produced from elastic materials were A.H/4+3, A.H/4+2, A.H/4+1 and the resulting order of appearance was A.H/4+3, A.H/4+2, A.H/4+1, order of comfort was A.H/4+3, A.H/4+2, A.H/4+1 and the order of movement functionality was A.H/4+1, A.H/4+2, A.H/4+3. Integrating these results shows that in using the same concurrent materials, the experiment pattern of setting the sleeve height as A.H/4+2 was the best while in using elastic materials, the experiment pattern of setting the sleeve height as A.H/4+3 was the best.

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Strong Higher Derivations on Ultraprime Banach Algebras

  • Lee, Young-Whan;Park, Kyoo-Hong
    • Journal of the Chungcheong Mathematical Society
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    • v.7 no.1
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    • pp.117-122
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    • 1994
  • In this paper we show that if {$H_n$} is a continuous strong higher derivation of order n on an ultraprime Banach algebra with a constant c, then $c||H_1||^2{\leq}4||H_2||$ and for each $1{\leq}l$ < n $$c^2||H_1||\;||H_{n-l}{\leq}6||H_n||+\frac{3}{2}\sum_{\array{i+j+k=n\\i,j,k{\geq}1}}||H_i||\;||H_j||\;||H_k||+\frac{3}{2}\sum_{\array{i+k=n\\i{\neq}l,\;n-1}}||H_i||\;||H_k|| $$ and for a strong higher derivation {$H_n$} of order n on a prime ring A we also show that if [$H_n$(x),x]=0 for all $x{\in}A$ and for every $n{\geq}1$, then A is commutative or $H_n=0$ for every $n{\geq}1$.

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2009 Pandemic Influenza A(H1N1) Infections in the Pediatric Cancer Patients and Comparative Analysis with Seasonal Influenza (소아암 환자에서 2009 대유행 인플루엔자 A(H1N1) 감염의 임상적 고찰 및 계절 인플루엔자와의 비교 분석)

  • Choi, Soo Han;Yoo, Keon Hee;Ahn, Kangmo;Sung, Ki Woong;Koo, Hong Hoe;Kim, Yae Jean
    • Pediatric Infection and Vaccine
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    • v.19 no.2
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    • pp.61-70
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    • 2012
  • Purpose: This study was performed to compare the clinical characteristics of 2009 pandemic influenza A(H1N1) [A(H1N1) pdm09] and seasonal influenza A infection in the pediatric cancer patients. Methods: A retrospective review was performed in the pediatric cancer patients who had confirmed A(H1N1)pdm09 infection at Samsung Medical Center from August 2009 to February 2010. For the comparison, the medical records of pediatric cancer patients with seasonal influenza A from January 2000 to May 2009 were reviewed retrospectively. Results: Eighty-two A(H1N1)pdm09 infections were confirmed in the pediatric cancer patients. Ten patients (12.2%) developed complicated clinical course by lower respiratory infections or extrapulmonary infections; 4 pneumonia, 1 bronchitis, 1 pericarditis with pneumonia, 1 encephalitis with pneumonia, 2 meningitis and 1 pericarditis. Three patients received mechanical ventilator and ICU care. Three pediatric cancer patients (3.7%) died. The risk factors related to complicated A(H1N1)pdm09 infections were date of infection (44-45th week 2009) and nosocomial infection. When comparing with previous seasonal influenza A infections, more prompt and aggressive antiviral therapy was given in A(H1N1)pdm09 infections. Conclusion: The A(H1N1)pdm09 infections caused a various clinical manifestations including fatal cases in pediatric cancer patient during pandemic season. There was no significant difference in clinical course between influenza A(H1N1)pdm09 and seasonal influenza A infections except the antiviral treatment strategy.

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Classification of strains of Xanthomonas oryzae on the basis of their susceptibility against bacteriophage (Bacteriophage의 감수성에 의한 수도백엽고병균의 계통분류)

  • Lee K. H.;Chung H. W.
    • Korean journal of applied entomology
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    • v.4
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    • pp.29-32
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    • 1965
  • 1. The 30 isolates of Xanthomonas oryzae collected from various places in Korea were classified into 2 strains in A' and B, by the 4 kinds of Japanese bacteriophages as follow; A' strain; Susceptible to $OP_1$ and $OP_2$ but not to $OP_1h$ and $OP_1h_2$. B strain; Susceptible to $OP_1h$, $OP_1h_2$ and $OP_2$ but not to $OP_1$. Of these bacterial strains, A' strain, a little different to A strain in Japan, was susceptible to $OP_1h_2$, while A' strain was resistant to $OP_1h_2$, 2. A' strain was widely and commonly distributed throughout this country, In geographical distribution, it was generally known that A' strain was distributed in south of Kyunggi-Do, whereas B strain was distributed north of Suwon area. 3. No specific tendency was found in the distribution of these strains in same variety.

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The H1*-H2* Measure

  • Ahn, Hyun-Kee
    • Speech Sciences
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    • v.7 no.2
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    • pp.85-95
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    • 2000
  • In this paper, the H1*-H2* measure is introduced and exact procedures for obtaining the H1*-H2* value are fully specified, The H1*-H2* measure (a corrected difference in dB between the first and second harmonics) has been devised to provide an acoustic correlate of the phonation mode of a vowel following a consonant. With this measure, we can investigate the phonation mode of a vowel that is free from the F1 amplitude perturbation effect caused by the preceding consonant, which is especially salient at the voicing onset position of the vowel. For identical research purposes, on the other hand, the H1-H2 measure (the observed difference in dB between the first and second harmonic) has been employed in many previous studies. This paper compares these two measures by illustrating experimental results of exploring post-release phonation modes of vowels following the different manner classes of stop consonants in Korean $\square$i.e., the tense, lenis, and aspirated stops.

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Genetic Analysis of the 2019 Swine H1N2 Influenza Virus Isolated in Korean Pigs and Its Infectivity in Mice (2019년 국내에서 분리한 H1N2 돼지 인플루엔자바이러스 유전자 분석 및 이의 마우스에 대한 감염성)

  • Jang, Yunyueng;Seo, Sang Heui
    • Journal of Life Science
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    • v.30 no.9
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    • pp.749-762
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    • 2020
  • Influenza A viruses are circulating in a variety of hosts, including humans, pigs, and poultry. Swine influenza virus is a zoonotic pathogen that can be readily transmitted to humans. The influenza viruses of the 2009 H1N1 pandemic were derived from swine influenza viruses, and it has been suggested that the 1957 H2N2 pandemic and the 1968 H3N2 pandemic both originated in pigs. Pigs are regarded as a mixing vessel in the creation of novel influenza viruses since they are readily infected with human and avian influenza viruses. We isolated three novel H1N2 influenza viruses from pigs showing respiratory symptoms on a Korean farm in 2019. These viruses were reassortants, containing PA and NP genes from those of the 2009 H1N1 influenza virus in addition to PB2, PB1, HA, NA, M, and NS genes from those of triple-reassortant swine H3N2 and classical swine H1N2 influenza viruses circulating in Korean pigs. Mice infected with the isolated H1N2 influenza virus lost up to 17% body weight and exhibited interstitial pneumonia involving infiltration of many inflammatory cells. Results suggest that close surveillance to detect emerging influenza viruses in pigs is necessary for the health of both pigs and humans.