• Journal of Periodontal and Implant Science
• /
• 제33권4호
• /
• pp.705-715
• /
• 2003

Procedures for treatment of molar furcation invasion defects range from open flap debridement, apically repositioned flap surgery, hemisection, tunneling or extraction, to regenerative therapies using bone grafting or guided tissue regenerative therapy, or a combination of both. Several clinical evaluations using regenerative techniques have reported the potential for osseous repair of treated furcation invasions. Regenerative treatment of maxillary molars are more difficult due to the multiple root anatomy and multiple furcation entrances therefore, purpose of this study was to evaluated histologically compomer and Ketac Silver as a barrier in the treatment of a bi-furcated maxillary premolar. Five adult beagle dogs were used in this experiment. With intrasulcular and crestal incision, mucoperiostcal flap was elevated. Following decortication with 1/2 high speed round bur, furcation defect was made on maxillary premolar. 2 month later one premolar was filled with compomer and the other premolar was filled with Ketac Silver. After 4, 8 weeks, the animals were sacrificed by vascular perfusion. Tissue block was excised including the tooth and prepared for light microscope with H-E staining. Results were as follows. 1. Compomer & Ketac Silver restoration were encapsulated fine connective tissue. 2. In 4 weeks, compomer & Ketac Silver restoration slightly infiltrated inflammatory cells but not disturb the new bone or new cementum formation. 3. In 8 weeks, compomer & Ketac Silver restoration were less infiltrated iflammatory cell and encapsulated fine connective tissue. 4. Therefore, compomer & Ketac Silver filling to the grade III maxillary furcations with multiple root anatomy and multiple furcation entrances is possible clinical method and this technique is useful method for maxillary furcation involvement but it is thought that periodic maintenance should be needed

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• 제10권1호
• /
• pp.341-363
• /
• 2016

Haze or fog is a common natural phenomenon. In foggy weather, the captured pictures are difficult to be applied to computer vision system, such as road traffic detection, target tracking, etc. Therefore, the image dehazing technique has become a hotspot in the field of image processing. This paper presents an overview of the existing achievements on the image dehazing technique. The intent of this paper is not to review all the relevant works that have appeared in the literature, but rather to focus on two main works, that is, image dehazing scheme based on atmospheric veil and image dehazing scheme based on dark channel prior. After the overview and a comparative study, we propose an improved image dehazing method, which is based on two image dehazing schemes mentioned above. Our image dehazing method can obtain the fog-free images by proposing a more desirable atmospheric veil and estimating atmospheric light more accurately. In addition, we adjust the transmission of the sky regions and conduct tone mapping for the obtained images. Compared with other state of the art algorithms, experiment results show that images recovered by our algorithm are clearer and more natural, especially at distant scene and places where scene depth jumps abruptly.

• 한국산학기술학회논문지
• /
• 제13권3호
• /
• pp.1337-1345
• /
• 2012

한반도 전구에서 적용되고 있는 EBO의 핵심교리는 측정 가능한 효과를 선정하여 최소의 전투로 승리하는 것이다. 이러한 EBO 교리를 고찰하여 무기체계 획득에 요구되는 방법론으로 V-C 연동체계 하에서의 효과분석 방법론을 연구 제시하였다. 제시된 방법론은 먼저 편성된 무기체계의 효과 정보를 확인하고 분석목적을 고려하여 MOE와 MOP, 효과를 설정하며 적정 무기체계의 운용개념과 시나리오 등을 적용하고 가용 C모델로 사후분석 조정 환류 하는 것이다. V-C 연동체계는 가상 합성 전장 환경에서의 실시간 전투실험을 가능케 한다. 이러한 V-C 연동체계에서 미래 대전차 유도무기체계의 방어전투 편성과 배치 등을 고려한 모델링으로 대대급 작전으로 중대급 개체를 운용하는 시나리오를 작성, AWAM을 구현하여 효과를 분석하고 SBA 토대를 구축하였다.

• 대한의용생체공학회:의공학회지
• /
• 제28권5호
• /
• pp.676-683
• /
• 2007

A non-invasive respiratory gated radiotherapy system like those based on external anatomic motion gives better comfortableness to patients than invasive system on treatment. However, higher correlation between the external and internal anatomic motion is required to increase the effectiveness of non-invasive respiratory gated radiotherapy. Both of invasive and non-invasive methods need to track the internal anatomy with the higher precision and rapid response. Especially, the non-invasive method has more difficulty to track the target position successively because of using only image processing. So we developed the system to track the motion for a non-invasive respiratory gated system to accurately find the dynamic position of internal structures such as the diaphragm and tumor. The respiratory organ motion tracking apparatus consists of an image capture board, a fluoroscopy system and a processing computer. After the image board grabs the motion of internal anatomy through the fluoroscopy system, the computer acquires the organ motion tracking data by image processing without any additional physical markers. The patients breathe freely without any forced breath control and coaching, when this experiment was performed. The developed pattern-recognition software could extract the target motion signal in real-time from the acquired fluoroscopic images. The range of mean deviations between the real and acquired target positions was measured for some sample structures in an anatomical model phantom. The mean and max deviation between the real and acquired positions were less than 1mm and 2mm respectively with the standardized movement using a moving stage and an anatomical model phantom. Under the real human body, the mean and maximum distance of the peak to trough was measured 23.5mm and 55.1mm respectively for 13 patients' diaphragm motion. The acquired respiration profile showed that human expiration period was longer than the inspiration period. The above results could be applied to respiratory-gated radiotherapy.

• 한국자원식물학회지
• /
• 제23권5호
• /
• pp.393-398
• /
• 2010

식용으로 사용되는 산채의 일종인 어수리의 지상부로부터 peroxynitrite 소거활성을 나타내는 성분을 분리한 결과 플라보노이드 성분인 hyperoside와 astragalin이 분리되었다. 특히, 높은 활성을 보였던 hyperoside는 이 식물재료 중 함량도 높아 어수리 잎은 peroxynitrite 과잉생산시 유발될 수 있는 당뇨병, 비만, 고지혈증, 심장질환 등의 예방과 치료에 유익한 식품이라 할 수 있을 것이다.

• 한국소음진동공학회논문집
• /
• 제23권3호
• /
• pp.249-257
• /
• 2013

This study newly presents a synthetic phase tuning technique to suppress the unwanted torsional mode while enhancing the desired torsional mode in a pipe. Specifically, we aim at the enhancement of the first torsional mode and the suppression of the undesired, second torsional mode. Earlier efforts were to enhance the desired wave mode only in the hope that the enhancement results in the suppression of the unwanted wave mode. Unlike these efforts, the suggested technique makes the complete cancellation of the unwanted wave mode but it is shown to enhance the desired first mode for torsional wave problems. In the present study, the synthetic phase tuning is developed for the cancellation of the unwanted wave mode, meaning that the number of necessary experimental equipments is reduced. Simulation and experiment were carried out to check the effectiveness of the proposed method. As an application of the suggested technique, we investigated the reflection and mode conversion characteristics of the first torsional mode according to the step thickness variation in a stepped pipe.

• 대한의용생체공학회:의공학회지
• /
• 제37권2호
• /
• pp.68-74
• /
• 2016

In this study, we investigated the rotational characteristics which were comprised of directionality and linearity of target registration error (TRE) as a study in advance to enhance the accuracy of contour-based registration in neuronavigation. For the experiment, two rigid head phantoms that have different faces with specially designed target frame fixed inside of the phantoms were used. Three-dimensional coordinates of facial surface point cloud and target point of the phantoms were acquired using computed tomography (CT) and 3D scanner. Iterative closest point (ICP) method was used for registration of two different point cloud and the directionality and linearity of TRE in overall head were calculated by using 3D position of targets after registration. As a result, it was represented that TRE had consistent direction in overall head region and was increased in linear fashion as distance from facial surface, but did not show high linearity. These results indicated that it is possible for decrease TRE by controlling orientation of facial surface point cloud acquired from scanner, and the prediction of TRE from surface registration error can decrease the registration accuracy in lesion. In the further studies, we have to develop the contour-based registration method for improvement of accuracy by considering rotational characteristics of TRE.

• 수산해양기술연구
• /
• 제44권2호
• /
• pp.99-111
• /
• 2008

The purpose of this study is to develop the jellyfish separator system(JSS) for reducing fishery damage by the increase of jellyfish in the sea area of Korea in summer. First of all, to find the optimum structure of a JSS, six types of JSS in trawl fishery were designed and manufactured, the underwater shape of JSS and the separating process by JSS were observed in the circulating water channel(CWC). And the field experiments were carried out in July and September 2004 in the southern sea of Korea. For the moving path of the jellyfish model in the CWC, in case that the model was larger than the mesh size of the separator net, it was guided toward the lower part of the separator net by the guiding net and discharged through the outlet. In case that the model was smaller than the mesh size of the separator net, some models which passed through the upper part of the guiding net were smaller than the mesh size of the guiding net and discharged through the outlet and most of the model which passed through the lower part of the guiding net moved to the codend passing through the separator net. According to the field experiment result, the optimum tilt angle of separator net was inferred $20^{\circ}$ that the discharge rate of jellyfish was higher than the other tilt angle of separator net and the optimum structure of JSS was inferred GS type(consists of guiding net and separator net) that the discharge rate of jellyfish was higher than S type(consists of separator net). It was demamded to carry out more study for the countermeasure to reduce loss of fish.

• Journal of Microbiology and Biotechnology
• /
• 제23권2호
• /
• pp.161-166
• /
• 2013

At present, acetylcholinesterase (AChE) inhibitors are the first group of drugs to treat mild to moderate Alzheimer's disease (AD). Although beneficial in improving cognitive and behavioral symptoms, the effectiveness of AChE inhibitors has been questioned since they do not delay or prevent neurodegeneration in AD patients. Therefore, in the present study, in order to develop new and effective anti-AD agents from lichen products, both the AChE inhibitory and the neuroprotective effects were evaluated. The AChE inhibitory assay was performed based on Ellman's reaction, and the neuroprotective effect was evaluated by using the MTT method on injured PC12 cells. One AChE inhibitor ($IC_{50}$ = 27.1 ${\mu}g/ml$) was isolated by means of bioactivity-guided isolation from the extract of lichen-forming fungus Cladonia macilenta, which showed the most potent AChE inhibitory activity in previous screening experiment. It was then identified as biruloquinone by MS, and $^1H$- and $^{13}C$-NMR analyses. The inhibitory kinetic assay suggested that biruloquinone is a mixed-II inhibitor on AChE. Meanwhile, biruloquinone improved the viability of the $H_2O_2$- and ${\beta}$-amyloid-injured PC12 cells at 1 to 25 ${\mu}g/ml$. The protective effects are proposed to be related to the potent antioxidant activities of biruloquinone. These results imply that biruloquinone has the potential to be developed as a multifunctional anti- AD agent.

• Journal of Periodontal and Implant Science
• /
• 제30권4호
• /
• pp.803-814
• /
• 2000

Current acceptable methods of promoting periodontal regeneration are basis of removal of diseased soft tissue, root treatment, guided tissue regeneration, graft materials, biological mediators. Platelet Rich Plasma have been reported as a biological mediator which regulate activities of wound healing progress including cell proliferation, migration, and metabolism. The purpose of this study is to evaluate the possibility of using the Platelet Rich Plasma as a regeneration promoting agent for furcation involvement defect. Five adult beagle dogs were used in this experiment. With intrasulcular and crestal incision, mucoperiosteal flap was elevated. Following decortication with 1/2 high speed round bur, degree II furcation defect was made on mandibular third(P3), forth(P4) and fifth(P5) premolar. 2 month later experimental group were PRP plus bovine bone and bovine bone only. After 4, 8 weeks, the animals were sacrificed by perfusion technique. Tissue block was excised including the tooth and prepared for light microscope with Gomori's trichrome staining. At 4 weeks after surgery, there were rapid osteogenesis phenomenon on the defected area of the Platelet Rich Plasma plus bovine bone group and early trabeculation pattern was made with new osteoid tissue produced by activated osteoblast. Bone formation was almost completed to the fornix of furcation by 4 weeks after surgery. In conclusion, Platelet Rich Plasma can promote rapid osteogenesis during early stage of periodontal tissue regeneration.