• 한국문헌정보학회지
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• 제48권4호
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• pp.267-295
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• 2014

본 연구에서는 소셜 러닝 커뮤니티에서 학습자의 심리적 요인, 지식소싱 행태, 지식활용 성과 간의 영향 관계 및 소셜 러닝과 구성원간 관계 요인이 갖는 매개효과를 실증적으로 분석하고, 일부 학습자를 대상으로 심층 면접 인터뷰를 실시하여 소셜 러닝 및 지식소싱에 영향을 미치는 심층적 요인을 살펴보고자 하였다. 이를 위해 2013년 1학기에 수도권 소재 대학교의 사회과학분야 학부생을 대상으로 연구를 진행하였다. 본 연구의 결과, 첫째, 학습자의 자기효능감은 소셜 러닝 활동참여에 영향을 미치고, 목표지향성은 그룹 지식소싱, 소셜 러닝 활동참여에 영향을 미치는 것으로 나타났다. 소셜 미디어의 이용경험은 그룹 지식소싱, 소셜 러닝 활동참여와 소셜 러닝 상호작용에 영향을 미치는 것으로 나타났다. 지식활용의 측면에서 문서 지식소싱은 지식재이용, 지식응용, 지식혁신에 영향을 미치고, 개인 지식소싱은 지식재이용에 영향을 미치며, 그룹 지식소싱은 지식응용, 지식혁신에 영향을 미치는 것으로 나타났다. 둘째, 소셜 러닝 활동참여는 목표지향성이 그룹 지식소싱에 영향을 미치는 관계와 소셜 미디어의 이용경험이 그룹 지식소싱에 영향을 미치는 관계에 모두 완전매개 효과를 갖고, 상호호혜성은 문서 지식소싱이 지식재이용에 영향을 미치는 관계와 문서 지식소싱이 지식혁신에 영향을 미치는 관계에 완전매개 효과를 갖는 것으로 나타났다. 셋째, 심층 면접 인터뷰 결과 학습자들은 전반적으로 소셜 네트워크 서비스를 통해 습득하는 정보가 신뢰할만하고 정보 습득에 용이하며, 여러 사람의 의견을 듣고, 그룹 활동을 통해 많은 지식을 습득하고 있는 것으로 나타났다.

• The Journal of Asian Finance, Economics and Business
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• 제8권10호
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• pp.109-117
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• 2021

This study investigates the effects of FDI and other macroeconomic variables on Total Factor Productivity (TFP) in selected ASEAN+3 countries from 1981 till 2016. Total Factor Productivity (TFP) for each ASEAN+3 country was constructed using the Malmquist productivity index method. Then, a panel ARDL framework (dynamic heterogeneous panel), namely Pooled Mean Group (PMG), Mean Group (MG), and Dynamic Fixed Effect (DFE) are employed in examining the effects of FDI and other controlling variables on TFP. The new findings show that FDI has a significant and positive impact on TFP in the long run and the short run in ASEAN+3 countries. Besides, the results also reveal that in the long run, other variables such as the average number of years of schooling and the ratio of high-skilled to low-skilled labor also have a significant and positive effect on TFP. However, economic openness, government expenditure on R&D, and interaction between countries and FDI have a negative and significant impact on TFP. These findings implied that the recipient countries must ensure their political stability and offer various incentives to attract more investors. Furthermore, the influx of foreign investors, especially large ones and lower costs, should be encouraged by each country as FDI inflows can boost their TFP growth.

• Journal of Microbiology and Biotechnology
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• 제34권2호
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• pp.306-313
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• 2024

Given the diversity of vegetables utilized in food fermentation and various lactic acid bacteria (LAB) populations in these materials, comprehensive studies on LAB from vegetable foods, including kimchi, are imperative. Therefore, this study aimed to investigate the obesity-related inflammation response of three metabolites-phenyllactic acid (PLA), indole-3-lactic acid (ILA), and leucic acid (LA)-produced by LAB (Companilactobacillus allii WiKim39 and Lactococcus lactis WiKim0124) isolated from kimchi. Their effects on tumor necrosis factor-α-induced changes in adipokines and inflammatory response in adipose-derived human mesenchymal stem cells were examined. The study results showed that PLA, ILA, and LA, particularly PLA, effectively reduced lipid accumulation and triglyceride, glycerol, free fatty acid, and adiponectin levels. Furthermore, the identified metabolites were found to modulate the expression of signaling proteins involved in adipogenesis and inflammation. Specifically, these metabolites were associated with enriched expression in the chemokine signaling pathway and cytokine-cytokine receptor interaction, which are critical pathways involved in regulating immune responses and inflammation. PLA, ILA, and LA also suppressed the secretion of pro-inflammatory cytokines and several inflammatory markers, with the PLA-treated group exhibiting the lowest levels. These results suggest that PLA, ILA, and LA are potential therapeutic agents for treating obesity and inflammation by regulating adipokine secretion and suppressing pro-inflammatory cytokine production.

• The Journal of Korean Physical Therapy
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• 제27권1호
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• pp.38-42
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• 2015

Purpose: Accuracy and variability of movement in daily life require synchronization of muscular activities through a specific chronological order of motor performance, which is controlled by higher neural substrates and/or lower motor centers. We attempted to investigate whether transcranial direct current stimulation (tDCS) over primary sensorimotor areas (SM1) could influence movement variability in healthy subjects, using a tapping task. Methods: Twenty six right-handed healthy subjects with no neurological or psychiatric disorders participated in this study. They were randomly and equally assigned to the real tDCS group or sham control group. Direct current with intensity of 1 mA was delivered over their right SM1 for 15 minutes. For estimation of movement variability before and after tDCS, tapping task was measured, and variability was calculated as standard deviation of the inter-tap interval (SD-ITI). Results: At the baseline test, there was no significant difference in SD-ITI between the two groups. In two-way ANOVA with repeated measurement no significant differences were found in a large main effect of group and interaction effect between two main factors (i.e., group factor and time factor (pre-post test)). However, significant findings were observed in a large main effect of the pre-post test. Conclusion: Our findings showed that the anodal tDCS over SM1 for 15 minutes with intensity of 1 mA could enhance consistency of motor execution in a repetitive-simple tapping task. We suggest that tDCS has potential as an adjuvant brain facilitator for improving rhythm and consistency of movement in healthy individuals.

• 한국의류학회지
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• 제33권10호
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• pp.1519-1529
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• 2009

This study investigates the influences of the impulse buying tendency of consumers, apparel price and scarcity messages on purchasing behavior at the time of purchase on the internet. This study was comprised of 2 (impulse buying: high versus low) $\times$ 2 (price of Internet purchase products: high apparel price versus low apparel price) $\times$ 2 (scarcity message: quantity scarcity message versus time scarcity message) with three mixed elements. The subjects of this study were 400 college students in the Seoul and Gyeonggi area. A total of 95 students who had a high tendency for impulsive purchase and 104 who had a low tendency participated in the survey. Data are analyzed by factor analysis, T-test, and ANOVA. The results of this study are as follows. 1. At the time of group buying on the Internet, impulse buying tendency, apparel price, and scarcity message had a statistically significant interaction effect on consumer preferences. 2. At the time of purchase on the Internet, impulse buying tendency, apparel price, and scarcity message did not have a statistically significant interaction effect on the intention of consumers to make a purchase. However, there was a significant difference in the intention to make a purchase based on impulse buying tendency and apparel price.

• BMB Reports
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• 제37권3호
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• pp.320-334
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• 2004

StMBF1 (Solanum tuberosum multiprotein bridging factor 1) is a plant member of the MBF1 family of transcriptional co-activators. In an attempt to understand the role of StMBF1, we analyzed its interaction with plant transcription factors of the homeodomain-leucine zipper (Hd-Zip) family, a group of proteins with a typical leucine zipper motif adjacent to a homeodomain. StMBF1 is able to interact in vitro with the Hd-Zip protein Hahb-4 both in the presence and absence of DNA. Upon binding, StMBF1 increases the DNA binding affinity of Hahb-4, and of another plant homeodomain containing protein from the GL2/Hd-Zip IV family, HAHR-1. The biological role of interactions is discussed in this paper.

• BMB Reports
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• 제39권3호
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• pp.311-318
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• 2006

One of the biggest group of proteins influenced by protein kinase CK2 is formed by factors engaged in gene expression. Here we have reported recently identified yeast transcription elongation factor Elf1 as a new substrate for both monomeric and tetrameric forms of CK2. Elf1 serves as a substrate for both the recombinant CK2$\alpha$' ($K_m$ 0.38 ${\mu}M$) and holoenzyme ($K_m$ $0.13\;{\mu}M$). By MALDI-MS we identified the two serine residues at positions 95 and 117 as the most probable in vitro phosphorylation sites. Co-immunoprecypitation experiments show that Elf1 interacts with catalytic ($\alpha$ and $\alpha$') as well as regulatory ($\beta$ and $\beta$') subunits of CK2. These data may help to elucidate the role of protein kinase CK2 and Elf1 in the regulation of transcription elongation.

• 대한간호학회지
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• 제53권3호
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• pp.340-358
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• 2023

Purpose: This study aimed to develop an instrument to showcase Dignity in Care of Terminally Ill Patients for Nurses and to examine its validity and reliability. Methods: A total of 58 preliminary items on dignity in care of terminally ill patients for nurses were selected using content validity analysis and expert opinions on 97 candidate items derived through a literature review and qualitative focus group interviews. Questionnaires were administered to 502 nurses caring for terminally ill cancer patients at hospice and palliative care institutions. The data were analyzed using item analysis, exploratory and confirmatory factor analysis, convergent and discriminant validity, and Pearson correlation for criterion validity, reliability was tested using Cronbach's alpha. Results: The final instrument consisted of 25 items, with four factors identified through confirmatory factor analysis. Four factors-ethical values and moral attitudes, interaction-based communication, maintaining comfort, professional insight and competence-accounted for 61.8% of the total variance. Cronbach's α for total items was .96, and test-retest reliability of intraclass correlation coefficient was .90. Conclusion: Since its validity and reliability have been verified through various methods, the Dignity in Care Scale of Terminally Ill Patients for Nurses can be used for develop nursing interventions and improve dignity in care of terminally ill patients.

• 감성과학
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• 제15권1호
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• pp.47-56
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• 2012

이 연구의 목적은 학습용 에이전트의 사실성 수준과 학습자의 전문성 수준이 학습 성취 및 에이전트에 대한 의인화 효과에 미치는 영향을 검증하기 위한 것이다. 대학생 68명(남학생= 19명, 여학생 = 49명)이 실험에 참여했으며, 전문성 수준은 사전검사의 평균을 기준으로 상위 집단과 하위 집단으로 구분하였다. 사실성 수준 은 에이전트 이미지를 단순화하는 정도에 따라서 구분하였다. 이 연구의 종속변수는 학습 성취와 의인화 효과에 대한 지각점수이다. 의인화 효과는 학습 촉진, 신뢰성, 인간다움, 학습 개입으로 구분하였다. 실험 결과에 따르면, 학습 성취에서는 에이전트 사실성 수준에 의한 유의미한 차이가 없었다. 그러나 의인화 효과에 대 한 설문에서는 학습 개입을 제외한 나머지 모든 범주에서 유의미한 상호작용이 나타났다. 단순 주 효과 분석에 따르면, 이런 상호작용의 효과는 전문성 수준이 높은 학습자가 정밀한 이미지의 에이전트를 제공받았을때 의인화 효과가 올라갔다. 이 결과는 학습자의 전문성 수준에 따라서 의인화 효과가 달라진다는 것을 보여 준다. 또한 전문성 수준이 높은 학습자는 에이전트에 대한 인지적 평가를 할 수 있었음을 의미한다. 전문성 수준이 높은 학습자에게는 사실성 수준이 높은 에이전트를 제공하는 것이 긍정적인 효과를 도출하였다.

• 한국학교보건학회지
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• 제12권1호
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• pp.45-56
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• 1999

Adolescence is vulnerable to various Health Risk Behaviors (HRB). These behaviors can affect his remaining life as well as adolescence, thus prevention of HRB is a critical issue in health education. This study is aimed to provide basic information for prevention of HRB. Thus, this study was conducted to analyze the impact of peer group's health risk behaviors on health risk perception (HRP) and that of health risk perception on health risk behaviors based on 832 respondents. The 852 subjects were selected in six middle and high schools in Seoul through random sampling. Data were collected from September, 18-October, 21, 1998, and the 832 data were analyzed after excluding the 20 incomplete and inaccurate data. Questionnaire items and measures are based on an instrument to measure Perceived Health Risk Perception, which Hodge B.C. developed in 1992. Cronbach alpha is used to test the reliability. The reliability of HRP and HRB is 0.9473, 0.8768 in this study, Statistical analysis divided into four phases. First, the impact of socio-demographic characteristics on HRP is analyzed by oneway ANOV A. Male students have lower HRP than female students. As grade goes up, HRP is getting lower. Perceived higher concern of parents and HRP are correlated. And the experience of school health education and HRP are correlated. Second, the impact of peer group's HRB on the HRP is analyzed by linear regression. Peer group's HRB and HRP are negatively correlated, Third, the impact of HRP on HRB is analyzed by linear regression. There is a correlation between high HRP and low HRB. Fourth, Powerful impact factors on HRB are analyzed by stepwise multiple regression. Grade, gender, peer group's HRB, and related HRP is entered as independent variables. Because of correlation between entered variables, three interaction variables between grade, gender, peer group's HRB and related HRP also entered, In general, peer group's HRB is the most accountable factor to HRB. And Interaction variable between HRP and peer group's HRB and HRB are negatively correlated. These results indicate that HRP may reduce the impact of peer group's HRB on HRB. Some recommendations are as follows: First, health educational programs suitable for gender and grade are required. Second, a systematic cooperation between school and home is necessary for effective prevention of HRB. Third, the educational effect for decreasing HRB by increasing HRP is statistically assisted. However, peer group has much stronger impact on HRB than subjective HRP, thus special consideration and management are necessary for peer group which does HRB more frequently.