This study was undertaken to investigate possibility of the allogenic type I collagen inducing osteoinduction or osteoconduction at critical sized bone defect in the rabbit. Twenty Newzealand white rabbit, weighted from 2.8 kg to 3.5 kg, were used in this study. The skull was exposed and two bony defects were created with diameter of 10 mm. Group I(n=10), the bony defects was grafted from the other side bone. Group II(n=10), the bony defects was grafted by the allogenic type I collagen with bone morphogenic protein(BMP). Group III(n=10), the bony defects was grafted by the allogenic type I collagen only. Group IV(n=10), the bony defects was lefted with no grafts. The grafted bones and allogenic type I collagen were investigated with radiologic densitometry, histologic analysis and immunohistochemistry after 12 weeks. No major difference was observed in the gross finding between Group I, II, III, but dura mater was exposed in bony defect,the Group IV. The radiologic study demonstrated more bony opacity in the Group I, but the other groups did not demonstrate a significant difference. In the histologic study, grafted bone edge was completely consolidated with original bone in group I and new bone ingrew into the grafted allogenic type I collagen(group II, III),but there is no bone regeneration from the original bony edge in the group IV. The percent of the new bone formation by cross-sectional area was considered statistically significant at a p value of less than 0.05(p<0.05). In the immunohistochemistry study about BMP antibodies, the group IV demonstrated osteogenic activity in front of advancing original bone edge, in which the osteoblast stained strongly for BMP antibodies, but other group does not demonstrated any osteoblastic expression. There was no immunologic rejection. In conclusion, this results do not demonstrate that the allogenic type I collagen is useful for bone substitute, but the characters of the collagen, such as pliability, easy-handling, sponge-like structure, are useful in interpositional bone graft substitutes. The further evaluation of long term results about the resorption, immunologic tissue reaction, response of applied tissue growth factor to the allogenic collagen is needed.
Mansour-Ghanaei, Fariborz;Sokhanvar, Homayoon;Joukar, Farahnaz;Shafaghi, Afshin;Yousefi-Mashhour, Mahmud;Valeshabad, Ali Kord;Fakhrieh, Saba;Aminian, Keyvan;Ghorbani, Kambiz;Taherzadeh, Zahra;Sheykhian, Mohammad Reza;Rajpout, Yaghoub;Mehrvarz, Alireza
Asian Pacific Journal of Cancer Prevention
/
v.13
no.4
/
pp.1407-1412
/
2012
Background & Objectives: Gastric cancer is a leading cause of cancer-related deaths in both sexes in Iran. This study was designed to assess upper GI endoscopic findings among people > 50 years targeted in a mass screening program in a hot-point region. Methods: Based on the pilot results in Guilan Cancer Registry study (GCRS), one of the high point regions for GC-Lashtenesha- was selected. The target population was called mainly using two methods: in rural regions, by house-house direct referral and in urban areas using public media. Upper GI endoscopy was performed by trained endoscopists. All participants underwent biopsies for rapid urea test (RUT) from the antrum and also further biopsies from five defined points of stomach for detection of precancerous lesions. In cases of visible gross lesions, more diagnostic biopsies were taken and submitted for histopathologic evaluation. Results: Of 1,394 initial participants, finally 1,382 persons (702 women, 680 men) with a mean age of $61.7{\pm}9.0$ years (range: 50-87 years) underwent upper GI endoscopy. H. pylori infection based on the RUT was positive in 66.6%. Gastric adenocarcinoma and squamous cell carcinoma of esophagus were detected in seven (0.5%) and one (0.07%) persons, respectively. A remarkable proportion of studied participants were found to have esophageal hiatal hernia (38.4%). Asymptomatic gastric masses found in 1.1% (15) of cases which were mostly located in antrum (33.3%), cardia (20.0%) and prepyloric area (20.0%). Gastric and duodenal ulcers were found in 5.9% (82) and 6.9% (96) of the screened population. Conclusion: Upper endoscopy screening is an effective technique for early detection of GC especially in high risk populations. Further studies are required to evaluate cost effectiveness, cost benefit and mortality and morbidity of this method among high and moderate risk population before recommending this method for the GC surveillance program at the national level.
Journal of the Korean Society for Marine Environment & Energy
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v.18
no.2
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pp.102-115
/
2015
Several emergy researches have been carried out to estimate the value of marine ecosystem services in Korea over the last decade. Their results cannot be compared mainly due to inconsistency in emergy-money ratios used to convert emergy unit into monetary unit. This study aimed at providing a standardized format for the emergy evaluation of the Korean economy and environment for different emergy evaluations to be compatible. Even though the area of the continental shelf increased in this study compared to those of previous studies, areaweighted average tidal range for the entire continental shelf of Korea resulted in smaller tidal range, decreasing the final emergy input from tide. However, emergy inputs from nonrenewable resources and purchased goods and services increased with new categorization and use of more detailed data, combined with updated unit emergy values. This led to higher emergy-money ratio for the Korean economy, indicating that previous emergy valuations might have overestimated the contributions of marine ecosystem to the real wealth of the Korean society. The base year for gross domestic product used in the emergy evaluation needs to be clearly indicated due to its impact on the calculation of the emergy-money ratio. A standardized emergy table for the Korean economy will contribute to ensuring consistency among future emergy researches on the valuation of marine ecosystem services.
With the global warming phenomenon, the deep sea water area that fishing vessels can enter and operate is ever widening. For example, the Arctic Ocean recently has overall competitive advantages due to having many deep-sea fish stocks. The North Pacific region is a strategic coastal district, the closest access point of Arctic Ocean. For Korean fishing vessels which now operate in North Pacific region, and want to entry the Arctic Ocean, the analysis of technical efficiency is needed for preparing the better industry's future. This paper aims to analyze the relative efficiency, and select the low effective deep-sea fishing vessels in the North Pacific, and to suggest their desirables strategies. As a research methodology, Data Envelopment Analysis (DEA) and Malmquist Index are applied to 16 fishing vessels for the periods(2009 to 2013). To draw out the efficiency of targeted deep-sea fishing vessels, gross tons, horsepowers, and operating days are used as input variables while total catch stands for an output variable. As a result, CCR efficiency, BCC efficiency and scalability efficiency are measured to be 0.8405, 0.9484 and 0.8858 respectively for 5 years (2009 to 2013). In conclusion, 38% of total tons, 36% of horsepowers and 29% of operating days each fishing vessel should be reduced to keep their competitive powers.
Lee, Sukjoon;Lee, Sang Wook;Hong, Bo Yeong;Eom, Hongmin;Shin, Hyu-Seok;Kim, Kyung-Min
Spatial Information Research
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v.22
no.3
/
pp.89-99
/
2014
The aim of this study is to represent the residential population distribution in Seoul, Korea more precisely through the dasymetric mapping method. Dasymetric mapping can be defined as a mapping method to calculate details from truncated spatial distribution of main statistical data by using ancillary data which is spatial data related to the main data. In this research, there are two types of data used for dasymetric mapping: the population data (2010) based on a output area survey in Seoul as the main data and the building footprint data including register information as ancillary spatial data. Using the binary method, it extracts residential buildings as actual areas where residents do live in. After that, the regression method is used for calculating the weights on population density by considering the building types and their gross floor areas. Finally, it can be reproduced three-dimensional density of residential population and drew a detailed dasymetric map. As a result, this allows to extract a more realistic calculating model of population distribution and draw a more accurate map of population distribution in Seoul. Therefore, this study has an important meaning as a source which can be applied in various researches concerning regional population in the future.
Park, Hong-Hyun;Kim, Kwang-Ho;Park, Chang-Gyu;Choi, Yong-Seok;Lee, Sang-Guei
Korean journal of applied entomology
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v.51
no.4
/
pp.383-388
/
2012
This study was conducted to assess damage to the welsh onion by Acrolepiopsis sapporensis Mastumura (Lepidoptera: Acrolepiidae) during the summer season, and to estimate the economic injury level (EIL) which results, providing basic data for pest management. The adult peaks of A. sapporensis in Suwon were observed in March, April, May, and September of 2009 and 2010 through the use of pheromone traps. The feeding of A. sapporensis results in white lines on the surface, and holes within welsh onions. During the entire larval period, one larva was able to damage 1.6 leaves and punch 11.9 holes, resulting in a total damaged leaf area of $1,321.6mm^2$. Through cage experiments and larval releases, a reduction of the mean number of leaves, increased percentage of leaf damage, and reduction in gross weight and marketable weight were observed. We could obtain a regression equation that showed a clear positive correlation between pest density and percentage of damaged leaf. Using this equation, the EIL of A. sapporensis on welsh onion was calculated to one larva per 10 plants based on 7% leaf damage observed for welsh onion.
Kim, Min-Keun;Yoo, Ki-Yeon;Kwon, Kwang-Jun;Kim, Seong-Gon;Park, Young-Wook;Lee, Kwang-Gill;Jo, You-Young;Kweon, Hae-Yong
Maxillofacial Plastic and Reconstructive Surgery
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v.36
no.3
/
pp.111-115
/
2014
Purpose: This study evaluated powdered burn wound dressing materials from wild silkworm fibroin in an animal model. Methods: Fifteen rats were used in this experiment. Full-thickness $2{\times}2cm$ burn wounds were created on the back of rats under anesthesia. In the two experimental groups, the wounds were treated with two different dressing materials made from silkworm fibroin. In the Control Group, natural healing without any dressing material was set as control. The wound surface area was measured at five days, seven days and 14 days. Wound healing was evaluated by histologic analysis. Results: By gross observation, there were no infections or severe inflammations through 14 days post-injury. The differences among groups were statistically significant at seven days and 14 days, postoperatively (P<0.037 and 0.001, respectively). By post hoc test, the defect size was significantly smaller in experimental Group 1 compared with the Control Group and experimental Group 2 at seven days postoperatively (P=0.022 and 0.029, respectively). The difference between Group 1 and Group 2 was statistically significant at 14 days postoperatively (P<0.001). Group 1 and control also differed significantly (P=0.002). Group 1 showed a smaller residual scar than the Control Group and Group 2 at 14 days post-injury. Histologic analysis showed more re-epithelization in Groups 1 and 2 than in the Control Groups. Conclusion: Burn wound healing was accelerated with silk fibroin spun by wild silkworm Antheraea pernyi. There was no atypical inflammation with silk dressing materials. In conclusion, silk dressing materials can be used for treatment of burn wound.
The Gross Merchandise Volume for the China's Singles day event in 2019 is about $38.4 billion. More than 500 million customers placed about 1.3 billion orders a day, and the related delivery volume is 2.8 billion. The main technologies associated with the 4th Industrial Revolution are bringing about a big change in the logistics industry. The purpose of this study is to present implications by reviewing the main technologies which are applied to China's Singles day event, the introduction of smart logistics in China, and analyzing the progress of Singles day, smart system of Alibaba, its significance. China still has poor infrastructure in non-capital areas. And many Chinese companies are actively introducing and developing smart logistics to cover the vast continental area of China. Singles Day is a representative case in point where the smart logistics and main technologies related to 4th Industrial Revolution are applied. The data obtained through smart logistics would be reused for inventory management, production planning, and order processing, contributing to the optimization of the company's operations. In the era of the 4th Industrial Revolution, domestic companies and governments need to make efforts to expand the introduction of smart logistics to secure competitiveness with global advanced companies.
BACKGROUND: A large scale of sediment load delivered from watershed causes substantial waterway damages and water quality degradation. Controlling sediment loading requires the knowledge of the soil erosion and sedimentation. The various factors such as watershed size, slope, climate, land use may affect sediment delivery processes. Traditionally sediment delivery ratio prediction equations have been developed by relating watershed characteristics to measured sediment yield divided by predicted gross erosion. However, sediment prediction equations have been developed for only a few regions because of limited sediment data. Besides, little research has been done on the prediction of sediment delivery ratio for asia monsoon period in mountainous watershed. METHODS AND RESULTS: In this study Tank model was expanded and applied for estimating sediment yield to Oship River of east coast. The rainfall-runoff in 2006 was verified using the Tank model and we derived good result between observed and calculated discharge in 2009 at the same conditions. In relation to sediment yield, the sediment delivery rate of 2006 was very high than 2009 regardless of methods for estimating sediment load. It was thought to be affected by heavy rainfall due to the typhoon. CONCLUSION(s): For estimating sediment volume from watershed, long-term monitoring data on discharge and sediment is needed. This model will be able to apply to predict discharge and sediment yield simultaneously in ungauged area. This approach is more effective and less expensive method than the traditional method which needs a lot of data collection.
Orb-web spiders can be considered as an effective bio-indicative animal to monitor the ecological air pollution of certain habitat since they have limited shifting ability during their life spans. In this study we revealed the fine structural characteristics of booklung in the orb-web spider Nephila clavata, and its bio-indicative significance in the monitoring environmental asbestos exposure. The high resolution scanning electron microscopy results suggest that the cuticular spikes near the atrium could be act as an effective filtering structure for dust materials. Furthermore, inner cuticular spikes which protruded across the air sacs, have the functions not only sustaining appropriate respiratory volume of each air sac but also help to enhance respiratory capacity by maximizing the gross surface area for gas exchange. Interestingly, in spite of short exposure, the asbestose fibrils were effectively captured on the surface of the atrial cuticular spikes. Furthermore, histologic damages were observed due to penetration of asbestos fibrils through air sacs and fixed on the hemolymph space. In addition, although accumulated mass of hemocytes were observed near the fibrils, there were no asbestos bodies or coagulated hemocytes were found on the surface of the fibrils, This could be mainly due to the short exposure period towards asbestos. Briefly, these results indicate the spider's booklung could be valuable tool in the detection ecological air pollutants.
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