• Title/Summary/Keyword: Glycerin

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Effects of Glycerin and PEG 400 in Donor and Receptor Solutions upon Skin Permeation of Drug (In vitro 경피흡수 실험시 Donor와 Receptor용액중의 글리세린과 PEG 400이 약물의 경피투과도에 미치는 영향)

  • Cho, Ae-Ri
    • Journal of Pharmaceutical Investigation
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    • v.26 no.2
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    • pp.99-103
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    • 1996
  • Effects of glycerin and PEG 400 in donor and receptor solutions upon skin permeation of drug were investigated. Deoxycortisone was used as a model compound. In vitro skin permeation study with freshly excised hairless mouse skin was performed and the steady-state skin permeation rates of the drug were determined in different fractions of glycerin or PEG 400 in donor and receptor solutions. Glycerin in donor solution didn't show any effect on the skin permeation rate of deoxycortisone. However glycerin in receptor solution showed significant effect on the skin permeation rate of the drug. In glycerin, there's a critical concentration for balancing hydration and dehydration of skin. At low concentration, less than 20 %, glycerin showed the enhancement of the flux due to the hydration effect of skin. At high concentration, more than 30 %, glycerin retard the permeation rate which might be due to the dehydration effect on the dermis layer. Since dermis has more water content than the stratum corneum, the steady state skin permeation rates were more influenced when glycerin was in receptor solution than that of in donor solution. PEG 400 aqueous solutions doesn't affect the steady state permeation rate of deoxycortisone significantly.

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Enhancement of the Critical Current Density of $MgB_2$ Prepared using Mechanically Milled and Glycerin Treated Boron Powder (기계적 밀링 및 글리세린 처리된 보론 분말을 사용하여 제조된 $MgB_2$의 임계전류밀도 향상)

  • Jun, Byung-Hyuk;Kim, Yi-Jeong;Kim, Chan-Joong
    • Progress in Superconductivity
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    • v.10 no.1
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    • pp.40-44
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    • 2008
  • A combined process of a mechanical ball milling and liquid glycerin ($C_{3}H_{8}O_3$) treatment of boron (B) powder has been conducted to enhance the superconducting properties of $MgB_2$. The individual aims of the mechanical milling and the glycerin treatment were to reduce the grain size of the $MgB_2$ and to achieve homogeneous carbon (C) incorporation into the $MgB_2$, respectively. Four kinds of B powders of as-received, glycerin treated, 2 h milled, and 2 h milled + glycerin treated were prepared. $MgB_2$ bulks were fabricated by in situ process using the prepared B powders. The mechanical ball milling was effective for a grain refinement, and a lattice disorder was easily achieved by glycerin addition. It was found that the critical current density ($J_c$) values were enhanced in the samples with milled B or glycerin treated B only. In the $MgB_2$ bulk prepared with both milled and glycerin treated B, the $J_c$ was further increased due to a higher grain boundary density and a greater C substitution.

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Preparation and Characterization of Poly(vinyl alcohol)/Poly(N-vinylpyrrolidone)/Glycerin/Chitosan Hydrogels by Radiation (방사선 가교에 의해 제조된 Poly(vinyl alcohol)/Poly(N-vinylpyrrolidone)/글리세린/키토산 하이드로겔의 제조 및 특성)

  • 박경란;노영창
    • Polymer(Korea)
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    • v.26 no.6
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    • pp.792-802
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    • 2002
  • In this study, hydrogels from mixtures of poly (vinyl alcohol) (PVA)/poly(N-vinylpyrrolidone) (PVP)/glycerin/chitosan were prepared by γ-ray irradiation and the mechanical properties such as gelation, water absorptivity, and gel strength were examined to evaluate the applicability of these for wound dressing. Then PVA:PVP was weight ratio of 6 : 4, the concentration of chitosan was 0.3 wt%, the concentration of glycerin was in the range of 0∼5 wt%t. The solid concentration of PVA/PVP/glycerin/chitosan solution was 15 wt%. Gamma irradiation doses of 25, 35, 50, and 60 kGy were exposed to a mixture of PVA/PVP/glycerin/chitosan to evaluate the effect of irradiation dose. Gel content and gel strength increased as glycerin concentration in PVA/PVP/glycerin/chitosan decreased, and as irradiation dose increased. Swelling degree increased as glycerin concentration in PVA/PVP/glycerin/chitosan increased, and as irradiation dose decreased. The glycerin in PVA/PVP/glycerini/chitosan hydrogel prevented the transformation of shape. These hydrogel dressings had better curing effect than vaseline gauge.

Effects of Petrolatum and Glycerin on Acetone Damaged Canine Skin Barrier

  • Oh, Won-Seok;Oh, Tae-Ho
    • Journal of Veterinary Clinics
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    • v.25 no.6
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    • pp.466-470
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    • 2008
  • The purpose of this study is to investigate whether the effects of topically applied petrolatum and glycerin on the barrier repair of acetone-induced skin damage in 6 beagle dogs. To confirm the effects of petrolatum and glycerin on acetone disrupted skin models, we performed to evaluate the characteristics of transepidermal water loss and SC hydration and scanning electron microscopic observations. TEWL and SC hydration measurements were carried out 3, 6, 12, 24, 48h after applying petrolatum and glycerin during recovery from acute disruption. Our results showed that there were some different effects between petrolatum and glycerin on the acetone damaged skin such as barrier function repair process and SC hydration status. The results indicate that the significant improvement could be observed in glycerin apply more than petrolatum after acetone damages, and further study will be required.

Effects of Glycerin and Sorbitol on the Ageing of Aluminum Hydroxide Gel (제산제에 관한 연구 (제 8 보) Glycerin 또는 Sorbitol의 첨가가 수산화 알루미늄.겔의 노화에 미치는 영향)

  • 유병설;홍문화
    • YAKHAK HOEJI
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    • v.6 no.2
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    • pp.13-17
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    • 1962
  • The effects of glycerin and sorbitol and ageing of antacid activity of aluminum hydroxide gel has been described. The results under accelerated temperatures showed sorbitol had excellent stabilizing effect and glycerin had promoting effect by contraries.

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Burn-out Finishing of Cotton/Polyester Fiber Mixed Fabrics using Cupric Sulfate (황산구리를 이용한 면/폴리에스터 교직물의 탄화가공)

  • 김수미;송화순
    • Journal of the Korean Home Economics Association
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    • v.42 no.8
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    • pp.113-121
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    • 2004
  • This study used cupric sulfate as a bum-out agent. The concentration of cupric sulfate, temperature and time were varied with glycerin included or excluded on the properties of polyester ground fabrics. The results are as follows. The effect of carbonization with glycerin included was decreased, but removal of carbide with glycerin included was easier than that with glycerin excluded. The white index and tensile strength of polyester ground fabrics were decreased as the processing concentration, temperature and time increased. The shrinkage was increased as the processing concentration, temperature and time increased. The optimum conditions with cupric sulfate as the bum-out agent was 5% concentration, 140$^{\circ}C$, 3min., and 3kgf/cm$^2$ and with cupric sulfate added to glycerin was 5% concentration, 150$^{\circ}C$, 5min., and 3kgf/cm$^2$.

The sensory Characteristics of Rice Extrudate by Addition of Emulsifier(Glycerin Fatty Acid Ester) (亂化劑(Glycerin fatty acid ester)添加에 따른 쌀 壓出 成型物의 官能的 特性)

  • 고광진
    • Journal of the East Asian Society of Dietary Life
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    • v.3 no.1
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    • pp.67-71
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    • 1993
  • This study ws prepared to evaluate sensory characteristics about appearance, color, texture and overall acceptability of rice extrudate with added glycerin fatty acid ester by balance incomplete block design. According to evaluated mean of adjusted treatments, appearance and color were represented maximum value in rice extrudate with added 3.0% and 1.0% glycerin fatty acid ester respectively. Extrudate with added 1.5% emulsifier revealed best texture and overall acceptability among whole treatments. On the results of this research about sensory characteristics, extrudate with added 1.5% glycerin fatty acid ester was considered excellent because of highest score of texture and overall acceptability, and predominent score of appearance and color.

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Anaerobic Co-digestion of Dairy Manure and Crude Glycerin (젖소분뇨와 Crude Glycerin의 통합혐기소화)

  • Lee, Sae-Min;Lee, Sang-Rak
    • Journal of Animal Environmental Science
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    • v.19 no.2
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    • pp.191-196
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    • 2013
  • In this study, the mixture ratio included 20% (GLY 20), 40% (GLY 40), and 60% (GLY 60) based on VS with the control group (GLY 0) with no crude glycerin added. Maintaining stable pH, GLY 20 and GLY 0 showed the highest total output of biogas (1.24 L/L/d) and methane(0.78 L/L/d) as its volatile solids reduction rate was 53.56%. In case of GLY 40 and GLY 60, their pH was rapidly reduced after seven days of the study, so that their anaerobic digestion was all stopped.In the results of the study, it is desirable to add crude glycerin less than 20%, and it would be necessary to have the future researches on more detailed organic loading rate of each ratio, and analysis on economic feasibility.

The Change of Superficial and Deep Heats in Ultrasound Application by Coupling Media (초음파 적용시 전파매질에 따른 표면열과 심부열의 변화)

  • Lee, Young-Hi;Kim, Jin-Sang
    • The Journal of Korean Physical Therapy
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    • v.12 no.2
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    • pp.57-67
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    • 2000
  • The purpose of this study was carried out in five rabbits of 3kg to investigate the change of superficial and deep heats in ultrasound application by coupling media. Temperature measured with thermistor needle at skin. subcutaneous, muscle in before coupling media application, after coupling media application. 2minutes. 5minutes, 7minutes, 10minutes. Coupling media was used gel, glycerin, distilled water. The data was analyzed using spss/pc+and t-test The results were as fallow : 1. With skin. gel was significant temperature change in 2minutes(p<.05). glycerin was significant temperature change in 2minutes(p<.05), 5minutes(p<.05), 7minutes(p<.01), 10minutes(p<.01). distilled water was significant temperature change in post coupling media(p<.05), 2minutes(p<.01). 5minutes(p<.05). 7minutes(p<.01). 10minutes(p<.01). With subcutaneous. gel was no temperature change. glycerin was significant temperature change in 2minutes(p<.05), 5minutes(p<.05), 10minutes(p<.01). distilled water was no temperature change. With muscle. gel was no temperature change. glycerin was significant temperature change in 2minutes(p<.05). 5minutes(p<.05). 7minutes(p<.05). 10minutes( p<.05). distilled water was significant temperature change in 10minutes(p<.05). 2. Superficial heats of skin and subcutaneous was higher temperature change than Deep heats of muscle. 3. Gel. glycerin. distilled Water required minimum treatment 10minutes fur thermal effect. 4. Gel was low temperature change superficial and deep heats. and glycerin was high temperature change superficial and deep heats. This results show that gel is high transmissiveness in the coupling media and glycerin is low transmissiveness in the coupling media.

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Carcass characteristics of lambs fed diets with increasing levels of crude glycerin

  • Costa, Caio Alves da;Carvalho, Francisco Fernando Ramos de;Guim, Adriana;Andrade, Gilcifran Prestes de;Cardoso, Daniel Barros;Maciel, Michel do Vale;Silva, Gabriela Goncalves da;Nascimento, Andreza Guedes de Oliveira
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.12
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    • pp.1882-1888
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    • 2019
  • Objective: An experiment was conducted to evaluate the effects of increasing levels of crude glycerin (0%, 6%, 12%, and 18%) used as a substitute for corn in lamb feed on the quantitative characteristics of the carcass. Methods: A total of 40 crossbred Santa $In{\hat{e}}s$ lambs that were four months old with a mean initial weight of $21.0{\pm}0.8kg$ were randomly distributed in four treatments with ten replicates. The animals were slaughtered after 66 days of confinement. The effects of crude glycerin as a replacement for corn in the diet of the lambs on the carcass characteristics, commercial cut weight and yield and carcass measurements were studied. Results: There was an increasing linear effect for body weight at slaughter with the replacement of corn by crude glycerin. The dry matter and metabolizable energy intakes, weight of the empty body, hot carcass weight and cold carcass weight showed a quadratic effect, with maximum crude glycerin levels estimated at 10.9%, 9.8%, 10.83%, 11.78%, and 11.35%, respectively. The initial pH was not influenced by the replacement of corn for crude glycerin, while the final pH presented a quadratic effect. The other parameters of the carcass and the weights and yields of commercial cuts were not influenced. There was also no effect of the diets on carcass morphometric measurements, except for the thoracic perimeter and the carcass compactness index, which presented quadratic and linear effects, respectively. Conclusion: Crude glycerin can replace up to 18% of corn because it favours muscle tissue deposition without promoting changes in the main carcass characteristics of lambs.