• Title/Summary/Keyword: Glycemic control

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Relationship between the Self-Reported Oral Health Status and Hemoglobin A1c Level among Diabetic Patients (일부 당뇨병 환자에서 당화혈색소 수치와 주관적 구강건강상태와의 연관성)

  • Choi, Jun-Seon
    • Korean Journal of Health Education and Promotion
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    • v.25 no.1
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    • pp.55-69
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    • 2008
  • Objective: This study was to investigate the relationship between hemoglobin A1c level and self-reported oral health status. Methods: The subjects of this study were 150 diabetic patients (60 male patients and 90 female patients) who went to the internal and family medicine departments of clinic. This study used the questionnaire and NYCOCARD$\square$ READERII to quantify hemoglobin A1c. Results: The proportion of well controlled diabetes subjects was 31.3%. When hemoglobin A1c levels became higher, subjects perceived that there were more decay teeth, bleeding, swollen gums, mobility teeth, and oral disease symptoms. In comparison with the well glycemic control group, poor glycemic control group perceived that the overall oral health status was worse, and had more bleeding teeth, swollen gums and mobility teeth. Conclusion: These results show that hemoglobin A1c level is related to the self-reported oral health status. Therefore, dental professionals should emphasize more the necessity of maintaining the hemoglobin A1c of normal range and monitoring it periodically, and the practice of thorough oral hygiene care in order to promote diabetic patients' oral health.

Long-limb Roux-en-Y Reconstruction after Subtotal Gastrectomy to Treat Severe Diabetic Gastroparesis

  • Park, Joong-Min;Kim, Jong Won;Chi, Kyong-Choun
    • Journal of Gastric Cancer
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    • v.19 no.3
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    • pp.365-371
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    • 2019
  • The role of surgical intervention in patients with diabetic gastroparesis is unclear. We report a case of a 37-year-old man with a history of recurrent episodes of vomiting and long-standing type 2 diabetes mellitus. Esophagogastroduodenoscopy did not reveal any findings of reflux esophagitis or obstructive lesions. A gastric emptying time scan showed prolonged gastric emptying half-time (344 minutes) indicating delayed gastric emptying. Laboratory tests revealed elevated fasting serum glucose and glycosylated hemoglobin (HbA1c, 12.9%) and normal fasting C-peptide and insulin levels. We performed Roux-en-Y reconstruction after subtotal gastrectomy to treat gastroparesis and improve glycemic control, and the patient showed complete resolution of gastrointestinal symptoms postoperatively. Barium swallow test and gastric emptying time scan performed at follow-up revealed regular progression of barium and normal gastric emptying. Three months postoperatively, his fasting serum glucose level was within normal limits without the administration of insulin or oral antidiabetic drugs with a reduced HbA1c level (6.9%). Long-limb Roux-en-Y reconstruction after subtotal gastrectomy may be useful to treat severe diabetic gastroparesis by improving gastric emptying and glycemic control.

Lifestyle factors related to glucose control for diabetes management strategies: Nested case control design using KNHANES data (당뇨병 관리전략을 위한 혈당조절 관련 생활습관 요인: 국민건강영양조사 활용 코호트내 환자-대조군 연구)

  • Kim, Yunjung;Cho, Eunhee
    • Journal of the Korea Convergence Society
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    • v.10 no.11
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    • pp.501-510
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    • 2019
  • This study aimed to find health related lifestyle factors that influence glycemic control for diabetes mellitus (DM) management strategies. This study used nested case-control design with matching variables that were not controlled by individuals such as age, sex, insulin or oral hypoglycemic agent (OHA) use, disease duration, education level and household income. This study analyzed 983 subjects with type 2 DM who enrolled in the $7^{th}$ (2016-2017) Korean National Health and Nutrition Examination Survey (KNHANES). The target HbA1c level of controlled glucose was defined as less than 6.5%, and 289 (30%) were achieved. Conditional multivariable logistic regression analysis was performed to find self-control factors associated with HbA1c levels. The results statistically significant for variables such as duration of diabetes, insulin or OHA use in overall cohort and body mass index (BMI), smoking and fundus Examination in matched cohort. These results are expected to provide as evidence for the intensive care criteria(disease duration, drug use) and lifestyle management strategy(BMI, smoking, fundus examination).

The Effect of a Self Regulation Education Program for the Promotion & Maintenance of Self Care Behavior in the Chronically ill patients -For Diabetic Patients- (만성질환자의 자기간호행위 증진과 지속에 대한 자기조절교육 프로그램의 효과 -당뇨병 환자를 중심으로-)

  • 구미옥
    • Journal of Korean Academy of Nursing
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    • v.26 no.2
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    • pp.413-427
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    • 1996
  • This study was conducted to test the effect of a self regulation education program as a nursing intervention with chronically ill patients. A quasi experimental research(non equivalent control group pretest-posttest design) was used in this study. The subjects were 30 non insulin dependent diabetic patients(experimental group : 14 patients, control group : 16 patients). The study was carried out from May, 1995 to February, 1996. Data were collected before the education program, immediately after & 2 menths later and were analyzed with repeated measure ANCOVA, paired t-test and t-test. The results are as follows : 1. There was a significant difference in self efficacy between the two groups(F=27.61, P=0.000). There was a significant difference according to experimental stages(F=33.09, P=0.000) and interaction between education and experimental stages(F=30.21, P=0.000). 2. There was a significant difference in self care behavior between the two groups(F=27.05, P=0. 000). There was a significant difference according to experimental stages(F=31.14, P=0.000) and interaction between education and experimental stages(F=28.88, P=0.000). 3. There was a significant difference in glycemic control between before the education program and 2 months iater in the experimental group (t=2.88, P=0.013). But there was no significant difference between before the education program and 2 months later in the control group. These results suggest that a self regulation education program is effective in promoting & maintaining self care behavior and in improving glycemic control.. Thus this program can be recommended as an effective nursing intervention for chronically ill patients including diabetic patients.

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Correlation among Serum and Urinary Calcium, Zinc, Magnesium and Other Factors in Non-Insulin Dependent Diabetic Women (인슐린 비의존형 당뇨병 여성환자의 혈청과 뇨중 칼슘, 아연 및 마그네슘 함량과 관련인자들과의 상관관계)

  • 주은정;차연수;박은숙
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.4
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    • pp.601-607
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    • 1996
  • Nineteen non-insulin-dependent diabetic(NIDD) and healthy control women were investigated to study the relationship between glycemic control and the level of calcium, zinc, and magnesium in the serum and urine. Urinary calcium, zinc and magnesium levels in the NIDD women were significantly higher(p<0.01) than those of the control women. There were no difference in serum magnesium and zinc levels between the two groups, but se겨m calcium level was lower(p<0.01) in the NIDD women compared to that of the control group. In the NIDD women, serum magnesium was negatively related to fasting blood glucose(r=-0.533 : p<0.05), urinary glucose(r=-0.767 ; P<0.001), urinary protein(r=-0.476 : p<0.05), and urine volume(r=-0.571 : p<0.05). The levels of zinc in both serum (r=0.515, p<0.05) and urine(r=0.623 : p<0.01) were related to urinary protein but only urinary zinc level(r=0.570 : p<0.01) was related to serum albumin. Urinary magnesium, not calcium was correlated with the urinary glucose(r=0.563 : p<0.05) and urinary protein(r=0.568 ; p<0.05). Fasting blood glucose was positively correlated with duration of diabetes, as well as dietary fat and calorie intake. The results of this study suggest that NIDD alters all magnesium, zinc, and calcium utilization, particularly magnesium is involved in glycemic control in this condition.

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Hepatic glycogenosis in type 1 diabetes mellitus mimicking Mauriac syndrome

  • Jung, In Ah;Cho, Won Kyoung;Jeon, Yeon Jin;Kim, Shin Hee;Cho, Kyoung Soon;Park, So Hyun;Jung, Min Ho;Suh, Byung-Kyu
    • Clinical and Experimental Pediatrics
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    • v.58 no.6
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    • pp.234-237
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    • 2015
  • Hepatic glycogenosis in type 1 diabetes mellitus (DM) can be caused by poor glycemic control due to insulin deficiency, excessive insulin treatment for diabetic ketoacidosis, or excessive glucose administration to control hypoglycemia. Mauriac syndrome, which is characterized by hepatomegaly due to hepatic glycogenosis, growth retardation, delayed puberty, and Cushingoid features, is a rare diabetic complication. We report a case of hepatic glycogenosis mimicking Mauriac syndrome. A 14-year-old girl with poorly controlled type 1 DM was admitted to The Catholic University of Korea, Seoul St. Mary's Hospital for abdominal pain and distension. Physical examination revealed hepatomegaly and a Cushingoid face. The growth rate of the patient had decreased, and she had not yet experienced menarche. Laboratory findings revealed elevated liver enzyme levels. A liver biopsy confirmed hepatic glycogenosis. Continuous glucose monitoring showed hyperglycemia after meals and frequent hypoglycemia before meals. To control hyperglycemia, we increased insulin dosage by using an insulin pump. In addition, we prescribed uncooked cornstarch to prevent hypoglycemia. After strict blood glucose control, the patient's liver functions and size normalized. The patient subsequently underwent menarche. Hepatic glycogenosis is a complication of type 1 DM that is reversible with appropriate glycemic control.

Effects of Mushroom Supplementation on Blood Glucose Concentration, Lipid Profile, and Antioxidant Enzyme Activities in Patients with Type 2 Diabetes Mellitus (표고버섯 보충이 제 2 형 당뇨병 환자의 혈당, 지질 대사 및 항산화 효소 활성에 미치는 영향)

  • Chang, Ji-Ho;Kim, Min-Sun;Kim, Jung-Yun;Choi, Woong-Hwan;Lee, Sang-Sun
    • Journal of Nutrition and Health
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    • v.40 no.4
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    • pp.327-333
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    • 2007
  • The present study was carried out to evaluate the physiological effects of mushroom supplementation on blood glucose levels, lipid profile, and antioxidant enzyme activities in subjects with type 2 diabetes mellitus. Subjects were randomized into either a control group or mushroom supplementation group. Mushroom supplementation was provided 3 times a day for 4 weeks. We found that total dietary fiber intake was about 2.5 times higher (30.3 g vs. 12.3 g) in subjects receiving mushroom supplementation than in the control group. Two groups maintained the same food intake and amount of activity, exercise during the supplementation. We observed no difference in age, height, weight, BMI (body mass index), blood pressure between the groups. Nutrient intake did not differ appreciably between the two groups, except for fiber intake, during the supplementation. Fasting blood glucose levels and 2-hour postprandial blood glucose levels were significantly lower in those ingesting mushroom than in controls. Furthermore, the concentrations of low-density lipoprotein cholesterol were decreased significantly in the mushroom supplementation group. Small changes were observed in the concentration of total cholesterol, triglyceride, high-density lipoprotein cholesterol of those supplemented with mushroom, but these changes were not statistically significant. Activities of superoxide dismutase and catalase with mushroom supplementation were higher than in controls, but and glutathione peroxidase activity was not affected. The levels of thiobarbituric acid reactive substance of mushroom group were lower than control group, but were not significant. We conclude that addition of mushroom influences glycemic control and may be effective in lowering blood lipids and improving antioxidant enzyme activities. Accordingly, such effects may reduce risk factors for cardiovascular disease in patients with type 2 diabetes. However, to confirm these effects and to make dietary recommendations for patients with type 2 diabetes, further studies are necessary.

Study on Quality and Blood Glucose Response of Roll Breads for Diabetes Mellitus (당뇨환자를 위한 롤빵의 품질과 혈당반응에 관한 연구)

  • 김명애;윤석권
    • The Korean Journal of Food And Nutrition
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    • v.13 no.5
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    • pp.419-424
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    • 2000
  • In order to develop the roll bread for diabetes mellitus patients, the roll bread mixed with soybean and barley flour to wheat flour was prepared and followed investigation of physical properties, sensory evaluation and blood glucose response of subjects. When soybean and barley flour was added more than 30%, hardness of mixed roll bread increased more than two times comparing to wheat flour. The roll bread mixed with 10% soybean flour was same in physical properties but was superior in sensory evaluation to wheat flour. While the blood glucose response after intake of roll bread mixed with soybean flour increased more slowly than that after intake of barley or wheat flour, glycemic index of soybean flour decreased. When roll bread was mixed with 10 to 30% soybean flour. the preference was almost same but control ability of blood glucose has improved comparing to adding barley or wheat alone.

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Anti-Glycemic and Anti-Lipid Effect of Ethanol Extract of Supungsunkihwan-gagambang in High Fat Diet-induced Obese Mice (수풍순기환가감방(搜風順氣丸加減方) 투여가 비만형 제2형 당뇨병 동물모델의 당대사 및 지질대사에 미치는 영향)

  • Song, Sang-Yel;Ahn, Se-Young;Ahn, Young-Min;Um, Jae-Young;Jang, Hyeung-Jin;Lee, Byung-Cheol
    • The Journal of Korean Medicine
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    • v.32 no.5
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    • pp.1-11
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    • 2011
  • Objectives: This study was undertaken to evaluate anti-glycemic and anti-lipid effects of Supungsunkihwan-gagambang, which is composed of Cornus officinalis, Dioscorea Batatas Decaisne, Auantii fructus and Platicodon grandiflorum. Methods: Diabetes was induced in ICR male mice ($24{\pm}1g$) with Surwit's high fat and high sucrose diet. Mice were divided into 3 groups (n=10) of normal, control and Supungsunkihwan-gagambang. The Supungsunkihwan-gagambang group was given 5% herbal medicine in their diet. The animals were fed on each experimental diet for 8 weeks. Body weight was assessed every week. At the 7th week, the fasting blood sugar (FBS) and oral glucose tolerance test (OGTT) were conducted in all experimental groups. After 8 weeks, fructosamine, lipid profile, epididymal fat weight, liver weight and white adipose tissue (WAT) size were measured. Results: Supungsunkihwan-gagambang significantly reduced FBS, OGTT and fructosamine. It also increased high density lipoprotein (HDL) cholesterol and significantly reduced triglyceride/HDL cholesterol ratio, total cholesterol/HDL cholesterol ratio and WAT size. Conclusions: These results show that Supungsunkihwan-gagambang improves anti-glycemic and anti-lipid effect in high fat diet-induced obese mice. Therefore we suggest that Supungsunkihwan-gagambang could be an effective treatment for patients with type 2 diabetes.