Anti-Glycemic and Anti-Lipid Effect of Ethanol Extract of Supungsunkihwan-gagambang in High Fat Diet-induced Obese Mice |
Song, Sang-Yel
(Dept. of Internal medicine, College of Oriental Medicine, Kyung Hee University)
Ahn, Se-Young (Dept. of Internal medicine, College of Oriental Medicine, Kyung Hee University) Ahn, Young-Min (Dept. of Internal medicine, College of Oriental Medicine, Kyung Hee University) Um, Jae-Young (Dept. of Pharmacology, College of Oriental Medicine, Kyung Hee University) Jang, Hyeung-Jin (Dept. of Biochemistry, College of Oriental Medicine, Kyung Hee University) Lee, Byung-Cheol (Dept. of Internal medicine, College of Oriental Medicine, Kyung Hee University) |
1 | Yamahara J.Yakugaku Zasshi. 1981;101(1):86-90. |
2 | Park YK. Hwuang WK, Kim IH. The Antidiabetic Effects of from Cornus officinalis Seed. Journal of pharmaceutical sciences. 1995;9:8-9. |
3 | Onat A, Hergenc G, Sari I, Karabulut A, Can G. Elevated LDL-cholesterol level predicts diabetes in centrally obese women but not men: relative roles of insulin resistance and central obesity. Circ J. 2007;71(9):1463-7. DOI ScienceOn |
4 | Lee BC, Kwon YG, Choi KL, Lee JS, Ahn YM, Ahn SY, et al. The Hypoglycemic Effect of Supungsunkihwan on Impaired Glucose Tolerance & Mild NIDDM Patiens. Korean J.Orient.Med. 2001;22(3):285-90. |
5 | Vetrichelvan T, Jegadeesan M. Anti-diabetic activity of alcoholic extract of Aerva lanata(L.) Juss.ex Schultes in rats. J Ethnopharm. 2002;80: 103-7. DOI ScienceOn |
6 | Jung UJ, Lee MK, Jeong KS, Choi MS. the hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice. J Nutr. 2004 Oct;134(10):2499-503. |
7 | Nugroho A, Park MG, Jin SE, Choi JS, Park HJ. Quantitative Analsysis of Flavanone Glycosides and Peroxynitrite Scavenging Effect of the Five Oriental Medicinal Drugs (Aurantii nobilis Pericarpium, Citrii unshiu Pericarpium, Citrii unshiu Semen, Aurantii Fructus, Poncirii Fructus). Kor. J. Pharmacogn. 2009;40(4):370-5. |
8 | 최문경. 지실 지각 등피의 기원 변천사와 공정서 규격 비교 연구[박사학위논문]. 부산: 동의대학교; 2010. |
9 | 허준. 원본동의보감. 서울: 남산당. 2004:717. |
10 | Cho SI, Son MW, Hong KE. Glycemic Control Effects of Sanyak (Dioscoreae rhizoma) extract in Prediabetic Stage Patients. J Korean Oreantal Med. 2010;31(5):146-66. |
11 | Ko BS, Kwon DY, Hong SM, Park SM. In vitro Anti-diabetic Effects of Crude Extracts of Platycodi Radix. Korean J. FOOD SCI.TECHNOL. 2007;39(6):703-6. |
12 | Kim JH, Kwon HS, Park YM, Lim SY, Lee JH, Lee SH, et al. Best surrogate marker for insulin resistance in middle aged non-diabetic Korean; Chungju metabolic syndrome study. Korean J Med. 2007;73(6):614. |
13 | Kim HJ. What Is the Most Useful Lipid Measure in Identifying Metabolic Syndrome and Insulin Resistance?. 2009:28. |
14 | Min HK. Clincal characteristics of Korean diabetic pattients. Kor. J. Diabetes. 1992; 13:163-70. |
15 | Ioannidis I, The road from obesity to type 2 diabetes. Angiology. 2008;59(2 Suppl):39S-43S. DOI |
16 | http://www.diabetes.or.kr/notice/list.php?code= broad. |
17 | 2010 인구주택총조사 전수집계 결과(인구부문). 2011;[1screens]. Available at URL:http://census.go.kr/ hcensus/ui/html/data/data_020_010_List.jsp?q_ menu=4&q_sub=2. Accessed September 30, 2011. |
18 | Jung UJ, Lee MK, Park YB, Kang MA, Choi MS. Effect of citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice. Int J Biochem Cell Biol. 2006;38(7):1134-45. DOI ScienceOn |
19 | Hus JH, Wu YC, Liu IM, Cheng JT. Release of acetylcholine to raise insulin secretion in Wistar rats by oleanolic acid, one of the active principles contained in Coruns officinalis. Neu- rosci Lett. 2006;404(1-2):112-6. |
20 | Kim MH. Effects of H2O fraction of Diascorea japonica Thunb with selenium on palsrma glucose and lipid metabolism in stretozotocim induced diadetic rats. The Kor. J. of Nutr. 1998;31:1377. |
21 | Dandona P, Aljada A, Chaudhuri A, Mohanty P, Garg R. Metabolic syndrome: A Comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation. 2005;111(11):1448-54. DOI ScienceOn |
22 | Simonen PP, Gylling HK, Miettinen TA. Diadtes contributes to cholesterol metabolism regardLess or obesity. Diabetes Care. 2002;25(9):1511-5. DOI ScienceOn |
23 | Lee SH, Ahn SY, Doo HK, Chung SH. Blood Glucose Lowering Activity and Mechanism of Supungsungihyan (SPSGH) in db/db Mouse.The journal of applied pharmacology. 1999;7:335-41. |
24 | Kang KM. Comparisons of Each Herbal Medicine in Sopungsungi-won for Antidiabetic Activity in C57BL/KsJ db/db Mice. 2003:40. |
25 | Baek SH. Prevention of Type 2 diabetes. Medical Postgra-duates. 2007;3:128-31. |
26 | Haffner SM, Stedrn MP, Hazuda HP, Mitchell BD, Patterson JK. Cardiovascular risk factors in confirmed pre-diabetic individuals: does the clock for coronary heart disease start ticking before the onset of clinical diabetes? JAMA. 1990;263:2893-8. DOI ScienceOn |
27 | Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M. Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial. JAMA 2003; 290(4):486-94. DOI ScienceOn |
28 | 전국한의과대학 신계내과학교실. 신계내과학. 서울:군자출판사. 2011:91. |
29 | Korea Centers for Disease Control and PreventIon. In-Depth Analysis on the 3rd (2005) Korea Health and Nutrition Examination Survey-Nutrition Survey-; 2007. |
30 | ikino H, Konno C, Takahashi M, Murakami M, Kato Y, Karikura M, et al. Isolation and hypoglycemic activity of Dioscorans A,B,C,D,E, and F; Glycans of Dioscorea japonica Rhizophors. Planta Med. 1986;52:168-71. DOI |
31 | Okuda TM. Proc Symp. WAKAN-YAKU. 1982; 15:9. |
32 | Park MH, Lee, YJ, Hwang SW, Han JP, Bae MJ. Effect of Platycodi radix Saponin on Serum, Liver, and Fecal Lipids Content in Rats Fed on High Fat Diet. J.Korean Soc.Food Nutr. 1994;23 (4):572. |
33 | Park JS. The effects of supungsunkihwan on high fat, high carbohydrate diet-induced obese type 2 diabetic mouse model. Kyung Hee University. 2009:24. |
34 | Bae MR. Hypoglycemic Effect and Mechanisms of Supungsungiwhan and partitioned prescriptions in High Fat Diet - Fed Mice. Kyung Hee University. 2000:48-9. |
35 | Byun BH, Seo BI. Effect of Platycodi Radix powder on Enzyme activities of Obese Rats Serum Fed High Fat Diet. Kor J.Herbology. 2003:18(4):135-9. |
36 | Kim YK. Establishing Efficacy Test Methods of Herbal Preparations in Metabolic Diseases. Wonkwang Univ.; 2007:16-7. |