• Title/Summary/Keyword: Global-Local Analysis

검색결과 969건 처리시간 0.034초

Biodistribution and PET imaging of [18F]FMISO in mousecolon cancer xenografted mice

  • Seelam, Sudhakara Reddy;Lee, Ji Youn;Kim, Young Joo;Lee, Yun-Sang;Jeong, Jae Min
    • 대한방사성의약품학회지
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    • 제1권2호
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    • pp.137-144
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    • 2015
  • Hypoxia is an important adverse prognostic factor for tumor progression and is a major cause of failure of radiation therapy. In case of short-term hypoxia, the metabolism can recover to normal, but if hypoxia persists, it causes irreversible cell damage and finally leads to death. So a hypoxia marker would be very useful in oncology. In particular, 2-nitroimidazole can be reduced to form a reactive chemical species, which can bind irreversibly to cell components in the absence of sufficient oxygen, thus, the development of radiolabeled nitroimidazole derivatives for the imaging of hypoxia remains an active field of research to improve cancer therapy result. 2-nitroimidazole based hypoxia marker, [$^{18}F$]FMISO holds promise for the evaluation of tumor hypoxia by Positron emission tomography (PET), at both global and local levels. In the present study, [$^{18}F$]FMISO was synthesized using an automatic synthesis module with high radiochemical purity (>99%) in 60 min. Immunohistochemical analysis using pimonidazole confirmed the presence of hypoxia in xenografted CT-26 tumor tissue. A biodistribution study in CT-26 xenografted mice showed that the increased tumor-to-muscle ratio and tumor-to-blood ratios from 10 to 120 min post-injection. In the PET study, [$^{18}F$]FMISO also showed increased tumor-to-muscle ratios from 10 to 120 min post-injection. In conclusion, this study demonstrates the feasibility and utility of [$^{18}F$]FMISO for imaging hypoxiain mouse colon cancer model using small animal PET.

효과적인 문자 인식을 위한 저 품질 문자 영상의 이진화 및 획 재구성 방법 (Binarization and Stroke Reconstruction of Low Quality Character Image for Effective Character Recognition)

  • 김도현;차의영
    • 한국정보통신학회논문지
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    • 제11권3호
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    • pp.608-618
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    • 2007
  • 영상의 이진화는 영상을 물체와 배경으로 구분하는 전처리 과정으로써 처리해야 할 대상이 되는 물체를 규정짓기 위한 매우 중요한 처리 과정이다. 본 논문에서는 저 품질 문자 영상에서 효과적인 문자 인식을 위한 효율적인 이진화 방법 및 획 영상 재구성 방법을 제안하다. 먼저 전역적 이진화 방법의 장점과 지역적 이진화 방법의 장점을 반영하여 문자 영역에 대한 이진화를 수행한 다음 이진화된 획 영상에 대한 분석을 통해 획에 붙어 있는 획 잡영 제거와 획 부분에 파여진 공백 잡영에 대한 채움 과정을 수행하여 고 품질의 획 영상으로 재구성하였다. 제안하는 문자 영상을 위한 이진화 알고리즘은 적응적인 임계값 선택 방법에 의해 속도와 성능의 효율성을 추구할 수 있도록 하였으며 이진화 결과로 인한 획 표면 잡영에 대해 단계적인 제거 과정을 수행하여 획 영상을 재구성함으로써 고 품질의 이진 영상을 획득할 수 있었다.

말레이시아 무슬림 여성의 패션제품 구매와 패션의식 (The Fashion Product Purchase and Fashion Consciousness of Malaysian Muslim Women)

  • 장선우;박혜원
    • 패션비즈니스
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    • 제25권2호
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    • pp.63-79
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    • 2021
  • In order to expand the overseas market of the Korean fashion industry, it is necessary to investigate the fashion-related purchases and fashion consciousness of Muslim women, who are increasingly attracting attention as global fashion consumers. Therefore a survey was conducted to identify the fashion design preferences and fashion consciousness of Malaysian Muslim women. A total of 245 responses were collected and analyzed. The survey included questions on demographic characteristics, fashion product purchases, design preferences and environmental awareness. The data were analyzed through frequency, average and standard deviation. The analysis showed that the majority of respondents were young Malaysian Muslim women in their 20s and 30s. They preferred a modern, Sophisticated, and sporty image, and their preference for unpatterned fabrics was high. When choosing fashion products, these women seek to both pursue fashion trends and comply with Islamic laws. When the women buy clothes, they consider practicality and design elements. The women also collected fashion trend information through SNS and the Internet, and ues this information to purchase fashion products through the Internet and shopping malls. This study was based on a practical survey of local consumers. Therefore, it is expected that the results can be used as data for fashion-related studies and to expand overseas markets to reach Muslim women in Southeast Asia.

한국 자동차의 대중국 수출경쟁력에 관한 연구 - RCA, CAC, ESI 지수 비교를 중심으로 (An Empirical Study on the Export Competitiveness of Korean Automobiles in the Local Chinese Market)

  • 김태헌
    • 국제지역연구
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    • 제13권3호
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    • pp.583-611
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    • 2009
  • 본고에서는 RCA지수, CAC지수, ESI를 이용하여 지난 2000년 이래 7년간 세계자동차시장 점유율 상위 6개국을 대상으로 중국시장에서의 자동차 수출경쟁력을 비교 분석하였다. RCA지수를 분석한 결과, 한국자동차의 국제시장에서의 경쟁력은 일본, 독일에 이어 높은 것으로 나타났으나 중국자동차시장에서는 수출경합국 중 최하위의 국제경쟁력을 가진 것으로 조사되었다. 국제시장에서 한국자동차의 RCA지수가 7년 평균 1.867인데 비해 중국시장에서의 CAC지수는 1.053에 불과하였다. 그러나 한국자동차는 프랑스시장에서 CAC지수 3.338, 미국시장에서 2.454, 독일시장에서 2.143, 일본시장에서 0.067을 기록함으로써, 프랑스, 미국, 독일시장에서 선전하고 있는 반면, 일본시장과 중국시장에서의 국제경쟁력은 매우 취약한 상태임을 확인할 수 있었다. 한편 세계자동차시장에서 한국자동차와 수출경합도가 가장 높은 국가는 독일과 일본으로 관측되었고, 중국시장의 경우 한국-독일, 한국-일본 수출경합도가 세계시장의 ESI보다는 미약하게 형성되어 있었다. 따라서 우리는 세계 및 중국자동차시장의 동향과 중국당국의 정책변화를 면밀하게 모니터링하고 업계와 정부간의 신속하고 유기적인 공조체제를 구축함으로써 중국시장의 경쟁체제 변화에 능동적으로 대응하는 전략을 강구해야 할 것으로 보인다.

A CPU-GPU Hybrid System of Environment Perception and 3D Terrain Reconstruction for Unmanned Ground Vehicle

  • Song, Wei;Zou, Shuanghui;Tian, Yifei;Sun, Su;Fong, Simon;Cho, Kyungeun;Qiu, Lvyang
    • Journal of Information Processing Systems
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    • 제14권6호
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    • pp.1445-1456
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    • 2018
  • Environment perception and three-dimensional (3D) reconstruction tasks are used to provide unmanned ground vehicle (UGV) with driving awareness interfaces. The speed of obstacle segmentation and surrounding terrain reconstruction crucially influences decision making in UGVs. To increase the processing speed of environment information analysis, we develop a CPU-GPU hybrid system of automatic environment perception and 3D terrain reconstruction based on the integration of multiple sensors. The system consists of three functional modules, namely, multi-sensor data collection and pre-processing, environment perception, and 3D reconstruction. To integrate individual datasets collected from different sensors, the pre-processing function registers the sensed LiDAR (light detection and ranging) point clouds, video sequences, and motion information into a global terrain model after filtering redundant and noise data according to the redundancy removal principle. In the environment perception module, the registered discrete points are clustered into ground surface and individual objects by using a ground segmentation method and a connected component labeling algorithm. The estimated ground surface and non-ground objects indicate the terrain to be traversed and obstacles in the environment, thus creating driving awareness. The 3D reconstruction module calibrates the projection matrix between the mounted LiDAR and cameras to map the local point clouds onto the captured video images. Texture meshes and color particle models are used to reconstruct the ground surface and objects of the 3D terrain model, respectively. To accelerate the proposed system, we apply the GPU parallel computation method to implement the applied computer graphics and image processing algorithms in parallel.

대학생의 스마트 학습관리시스템 수용에 대한 연구 - 블랙보드 도입과 활용 - (College student adoption of smart learning management system - Implementing Blackboard learn -)

  • 이규혜;김지연;서현진
    • 복식문화연구
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    • 제27권5호
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    • pp.512-523
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    • 2019
  • Contemporary University students are considered the Z generation who were born after 1995. They are more tech savvy than millennials. To target the generation, traditional class management platforms have evolved to smart LMS that is more customized and accessible for smart devices. Global level information search and collaboration can also be implemented using such smart LMS. However, switching from one LMS to another LMS requires great effort from teachers and support from staffs. This study measured the learners' perception of the system when they were exposed to a new smart-LMS. Blackboard Learn Ultra was used for 15 weeks and at the end of the semester, a questionnaire was administered to the students of these classes. Results indicated that experience with previous LMS discouraged students from adopting Blackboard Learn. Result of TAM modeling indicated that perceived usefulness, compared to perceived ease of use and attitude, was an effective aspect to bring positive acceptance of the system. A qualitative approach and network analysis were also conducted based on students' responses. Both positive and negative responses were detected. Inconvenience due to mechanical aspects was mentioned. Dissatisfaction compared to previous local LMS use was also mentioned. Mobile application and communication effectiveness were positive aspects. Revised course development and promoting how useful the system may help enhance the acceptance of the new system.

Behavior of three-tube buckling-restrained brace with circumference pre-stress in core tube

  • Li, Yang;Qu, Haiyan;Xiao, Shaowen;Wang, Peijun;You, Yang;Hu, Shuqing
    • Steel and Composite Structures
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    • 제30권2호
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    • pp.81-96
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    • 2019
  • The behavior of a new Three-Tube Buckling-Restrained Brace (TTBRB) with circumference pre-stress (${\sigma}_{{\theta},pre}$) in core tube are investigated through a verified finite element model. The TTBRB is composed of one core tube and two restraining tubes. The core tube is in the middle to provide the axial stiffness, to carry the axial load and to dissipate the earthquake energy. The two restraining tubes are at inside and outside of the core tube, respectively, to restrain the global and local buckling of the core tube. Based on the yield criteria of fringe fiber, a design method for restraining tubes is proposed. The applicability of the proposed design equations are verified by TTBRBs with different radius-thickness ratios, with different gap widths between core tube and restraining tubs, and with different levels of ${\sigma}_{{\theta},pre}$. The outer and inner tubes will restrain the deformation of the core tube in radius direction, which causes circumference stress (${\sigma}_{\theta}$) in the core tube. Together with the ${\sigma}_{{\theta},pre}$ in the core tube that is applied through interference fit of the three tubes, the yield strength of the core tube in the axial direction is improved from 160 MPa to 235 MPa. Effects of gap width between the core tube and restraining tubes, and ${\sigma}_{{\theta},pre}$ on hysteretic behavior of TTBRBs are presented. Analysis results showed that the gap width and the ${\sigma}_{{\theta},pre}$ can significantly affect the hysteretic behavior of a TTBRB.

An Adaptive Local Management Approach Cannot Overcome Large-Scale Trends: A Long-Term Case-Study for Saxifraga hirculus Conservation

  • Marrs, Rob H.;O'Reilly, John;Rose, Rob J.;Lee, HyoHyeMi;Alday, Josu G.
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • 제3권3호
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    • pp.139-148
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    • 2022
  • Saxifraga hirculus is classified as a vulnerable plant species in Europe, and it is confined to base-rich flushes in the British uplands. However, a lack of available information about its conservation status hampers the development of adaptive strategies for its in-situ conservation, especially with respect to grazing. To assess the effectiveness of sheep grazing in maintaining viable populations of S. hirculus, we compared the community dynamics of the vegetation in a base-rich flush over 44 years in two plots: one sheep-grazed under business-as-usual sheep grazing densities and the other fenced to exclude grazing. The plots were established in 1972, and the abundances of all vascular plants, bryophytes, and litter were measured at six intervals until 2016. Our results showed that although the presence of S. hirculus was maintained in both plots over the 44 years, it declined and reached a minimum between 1995 and 2010, when it was close to extinction. Since 2013, Saxifraga has recovered only slightly. Interestingly, the S. hirculus response appeared to be independent of grazing treatment, but it mirrored wider changes in the vegetation composition and structure within the flush over the 44 years. These changes are similar to others reported in broader uplands that have been attributed to a combination of reduced nitrogen and sulfur deposition and global warming. Thus, the simple adaptive management approach of "just managing" sheep grazing appeared ineffectual for preserving the S. hirculus population. S. hirculus showed signs of recovery at the end of the study period within this base-rich flush.

A Study on Port Improvement with the Activation of Cross-Border E-Commerce: A Study of Pyeongtaek Port

  • Choi, Hyuk-Jun;Jung, Hyun-Jae;Lee, Dong-Hyon
    • Journal of Korea Trade
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    • 제23권7호
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    • pp.34-44
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    • 2019
  • Purpose - The purpose of this study is to present what the port of Pyeongtaek, the hub of Korean trade with China, should improve in the current situation, wherein the e-commerce trade volume between Korea and China is increasing due to the development of online technology. Design/methodology - In this study, through prior research and expert interviews on e-commerce and port activation between borders, we derived the main improvement factors for 1) Administration and Systems, 2) Facilities, 3) Transport, and 4) Manpower, and selected 12 detailed variables for the major improvement factors. To identify the relative importance of the major improvement factors, the Analytic Hierarchy Process (AHP) method was applied, and a survey was conducted among 15 related experts. Findings - As a result, among the 12 detailed variables, Composition of Association (0.267) was the first factor to be improved, followed by Incentive Support (0.143) and E-Commerce Cluster (0.131). Based on these analyses, the main implications of this study are, first, in the current situation where the cross-border e-commerce market is growing, Pyeongtaek Port needs to form a consultative body among the government, local governments, and related businesses in connection with cross-border e-commerce and develop various support policies for the e-commerce market. Second, it will have to be able to provide differentiated services from competing ports by establishing e-commerce market-oriented clusters. Originality/value - In existing related studies, various improvements were presented to revitalize trade in line with the growth of the cross-border e-commerce market. However, with regard to most cross-border e-commerce businesses, one-dimensional improvement measures, such as improvement of payment systems, improvement of customs clearance services, and promotion of human resources, are presented in a piecemeal manner. In other words, none of the studies have proposed the importance and priority of each measure in terms of both the forward-looking and efficient allocation of resources, which is the purpose of this study. Therefore, this study contributed politically, practically, and academically by presenting countermeasures for ports to revitalize cross-border e-commerce and presenting strategic priorities using quantitative analysis methods.

스마트관광도시 경쟁력 지표 개발과 적용 (Developing and Applying Smart Tourism Cities Competitiveness Index)

  • 이현애;구철모;정희정;정남호
    • 정보화정책
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    • 제29권4호
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    • pp.91-108
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    • 2022
  • 근대적 방식의 관광 개발이 야기한 여러 도시 문제들에 대한 해결책으로 '스마트관광도시'가 주목받고 있다. 그러나 스마트관광도시로의 발전을 위한 구체적인 방향이나 지침이 부족한 상황에서 일부 지자체들은 천편일률적인 관광앱을 개발하는데 막대한 투자비용을 들이고 있다. 이에 본 연구는 국내·외의 주요 관광도시에 두루 적용할 수 있는 표준화되고 객관적인 '스마트관광도시 경쟁력 지표'를 개발하고, 서울을 포함한 세계 여러 도시들의 스마트관광도시 경쟁력 수준을 평가하고자 하였다. 평가 지표는 매력성, 접근가능성, 디지털 준비도, 지속가능성, 마지막으로 협력적 파트너십으로 구성되었다. 도시별 분석 결과, 싱가포르가 가장 높은 수준의 스마트관광도시 경쟁력을 갖고 있는 것으로 평가되었으며, 이어 암스테르담, 뉴욕, 서울, 바르셀로나, 코펜하겐의 순으로 나타났다. 반면 호치민과 방콕은 상대적으로 스마트관광도시화에 더 많은 노력이 필요한 것으로 나타났다. 이를 통해 향후 스마트관광도시 관련 사업들을 지속적이고 체계적으로 모니터링 할 수 있는 글로벌 표준으로도 활용하여 유의미한 시사점을 제시할 수 있을 것으로 기대된다.