• Fisheries and Aquatic Sciences
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• 제26권12호
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• pp.752-761
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• 2023

Genetic diversity serves as the basis for selecting and genetically enhancing any culturable species in aquaculture. Here, two different strains of wild (River Ravi and River Kabul) and six captive-bred strains of Labeo rohita from various provinces were se- lected, and genetic diversity among them was evaluated using three different microsatellite markers, i.e., Lr-28, Lr-29, and Lr-37, and one mitochondrial CO1 (Cytochrome c oxidase subunit 1) gene. Different strains of L. rohita were collected, and part of their caudal fin was cut and preserved in ethanol for DNA extraction and determination of genetic diversity among them. Results in- dicated that selected markers were polymorphic with polymorphic information content (PIC) content values above 0.5 with the highest in Lr-28 followed by Lr-29 and then Lr-37. The observed heterozygosity (Ho) of all strains was higher (Avg: 0.731) but less than the expected heterozygosity (He). Moreover, TMs and WRs showed the highest He, while TKs showed the lowest, He. Over- all, inbreeding coefficient (FIS) values observed for all strains with selected markers were positive. The DNA barcoding with the CO1 gene revealed genetic variation among various strains, as demonstrated by the clades in the phylogenetic tree separating the strains into two distinct clusters that then divided into sub-clusters. In conclusion, TMs showed the highest heterozygosity as compared to other strains. Overall results provide the baseline data for the initiation of the genetic improvement program.

• 수산해양기술연구
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• 제39권4호
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• pp.284-290
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• 2003

It is very important to minimize the weight of shaft from the viewpoint of economics and manufacture. For minimizing effectively the diameter of shaft in torsional shafting, authors developed computer program using the real-coded genetic algorithm which is one of optimizing techniques and based on real coding representation of genetic algorithm. In order to confirm the accuracy and effectiveness of the developed computer program, the computational results by the developed program were compared with those of conventional strength, stiffness and vibration designs for a generator shafting.

• 한국정밀공학회지
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• 제21권9호
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• pp.174-181
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• 2004

Recently, many studies have been undergoing to reduce working time in field of machine tool. There are two ways of reducing working time to reduce actual working time by heighten spindle speed and to reduce stand-by time by shortening tool exchange time. Auto tool changer belongs to latter case. Fixed address type auto tool changer can store more number of tools in small space than magazine transfer Ope and can shorten tool exchange time. This study focuses on the topology optimization to reduce the weight of the fixed address type ATC. The optimization program using a real number coding genetic algorithm is developed and is applied to the 10-bar truss optimization problem to verify the developed program. And, it is shown that the developed program gives better results than other methods. Finally, The developed program applied to optimize the fixed address type ATC.

• EDISON SW 활용 경진대회 논문집
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• 제4회(2015년)
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• pp.484-487
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• 2015

The purpose of this study is designing a daily diet according to the nutrition by using genetic algorithms. The ratio of the amount of nutrients needed for each individual is different. For example, people who want to lose, maintain or gain the weight need different amount of nutrition and ratio. In addition, the nutrition should be different between the age groups such as child, youth and senior. So, it is important for each person to individualize content of nutrition that they need not the nutritional standard table. Thus, in this study, by using the genetic algorithm, our study is about the program that can make a daily diet which is optimized for individual. The program has the information of main dish, soup and side dish that we entered before. And person who uses the program can see the daily diet which is optimized related by nutrition what the person entered before. Generally, it is really difficult to design a meal by considering all of the nutrition at home because there are a lot of things to be considered. Therefore, the goal of our study is to make the program what can make a balanced daily diet at home.

• 성인간호학회지
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• 제20권6호
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• pp.815-828
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• 2008

Purpose: This study was to develop and evaluate the clinical utility of the breast and ovarian cancer genetic counselling program specific for 20 Korean women(KBOCGP). Methods: The KBOCGP was developed using three types of approaches: an ethnography among Korean women who underwent BRCA1/2 test, designing and implementing one week clinical genetic educational course for clinical cancer nurses, educational observation visits to three American cancer genetic counselling programs. And then pre-experimental design was implicated to evaluate the change of the women's knowledge about the hereditary breast and ovarian cancer and the level of the satisfaction with genetic counselling. Results: The mean score of the knowledge has significantly increased from $7.45{\pm}3.86$ to $11.55{\pm}2.21$ (t = 5.63, p < .001). The level of the satisfaction with the counselling was very high ($27.47{\pm}1.35$). Because most of the subjects have young kids, they showed strong concerns about their kids' getting cancer. Conclusion: This new KBOCGP is the satisfactory program for the education and communication of the genetic information to the Korean women with HBOC. But it is needed more to strengthen the cultural sensitivity especially to Korean family relationships. Authors recommend that this program be provided by other nurses who are counselling women at high risk of breast cancer.

• Asian-Australasian Journal of Animal Sciences
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• 제33권1호
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• pp.12-23
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• 2020

Objective: The objective of a conservation program is to maintain maximum genetic diversity and preserve the viability of a breed. However, the efficiency of a program is influenced by the ability to accurately measure and predict genetic diversity. Methods: To examine this question, we conducted a simulation in which common measures (i.e. heterozygosity) and novel measures (identity-by-descent probabilities and parental genomic components) were used to estimate genetic diversity within a conserved population using double-labeled single nucleotide polymorphism markers. Results: The results showed that the accuracy and sensitivity of identity-by-state probabilities and heterozygosity were close to identity by descent (IBD) probabilities, which reflect the true genetic diversity. Expected heterozygosity most closely aligned with IBD. All common measures suggested that practices used in the current Chinese pig conservation program result in a ~5% loss in genetic diversity every 10 generations. Parental genomic components were also analyzed to monitor real-time changes in genomic components for each male and female ancestor. The analysis showed that ~7.5% of male families and ~30% of female families were lost every 5 generations. After 50 generations of simulated conservation, 4 male families lost ~50% of their initial genomic components, and the genomic components for 24.8% of the female families were lost entirely. Conclusion: In summary, compared with the true genetic diversity value obtained using double-labeled markers, expected heterozygosity appears to be the optimal indicator. Parental genomic components analysis provides a more detailed picture of genetic diversity and can be used to guide conservation management practices.

• Animal cells and systems
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• 제12권4호
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• pp.269-277
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• 2008

Siberian flying squirrel, an endangered species in South Korea, is distributed through major mountain regions of South Korea. The number of Siberian flying squirrel(Pteromys volans) in South Korea has decreased and their habitats are fragmented and isolated because of anthropogenic activities. So far no molecular genetic data has, however, been available for their conservation and management. To obtain better information concerning genetic diversity and phylogenetic relationships of the Siberian flying squirrel in South Korea, we examined 14 individuals from South Korea, 7 individuals from Russia, and 5 individuals from northeastern China along with previously published 29 haplotypes for 1,140 bp of the mtDNA cytochrome b gene. The 14 new individuals from South Korea had 7 haplotypes which were not observed in the regions of Russia and Hokkaido. The level of genetic diversity(0.616%) in the South Korean population was lower than that in eastern Russia(0.950%). The geographical distribution of mtDNA haplotypes and reduced median network confirmed that there are three major lineages of Siberian flying squirrel, occupying; Far Eastern, northern Eurasia, and the island of Hokkaido. The South Korean population only slightly distinct from the Eurasia, and eastern Russian population, and is part of the lineage Far Eastern. Based on these, we suggest that the South Korean population could be considered to belong to one partial ESU(Far Eastern) of three partial ESUs but a different management unit. However, the conservation priorities should be reconfirmed by nuclear genetic marker and ecological data.

• 한국자원식물학회지
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• 제32권3호
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• pp.244-253
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• 2019

In crop breeding program, information about genetic dissimilarity on breeding resources is very important to corroborate genealogical relationships and to predict the most heterozygotic hybrid combinations and inbred breeding. This study aimed to evaluate the genetic variation in Kenyan sunflower breeding lines based on simple sequence repeat (SSR). A total of 83 alleles were detected at 32 SSR loci. The allele number per locus ranged from 2 to 7 with an average of 2.7 alleles per locus detected from the 24 sunflower accessions and the average value of polymorphic information contents (PIC) were 0.384. A cluster analysis based on the genetic similarity coefficients was conducted and the 24 sunflower breeding resources were classified into three groups. The principal coordinates (PCoA) revealed 34% and 13.38% respectively, and 47.38% of total variation. It was found that the genetic diversity within the Kenyan sunflower breeding resources was narrower than that in other sunflower germplasm resources, suggesting the importance and feasibility of introducing elite genotypes from different origins for selection of breeding lines with broader genetic base in Kenyan sunflower breeding program.

• 한국전자파학회논문지
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• 제15권9호
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• pp.856-862
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• 2004

유전자 알고리즘을 사용하여 전파 잡음의 통계적 모형(APD: amplitude probability distribution)으로부터 최적파라미터를 추출, 데이터베이스화하는 프로그램을 개발하였다. 제안된 파라미터 추출 방법은 기존의 시행 착오법과 비교하여 추출 시간이 단축되고 추출과정의 자동화가 가능하며 각 파라미터별로 국부적 최적화가 아닌 전역적 최적화를 시행할 수 있다는 장점을 가지고 있다.

• 동력기계공학회지
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• 제9권4호
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• pp.202-208
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• 2005

The genetic algorithm (GA) which is one of the popular optimum algorithm has been used to solve a variety of optimum problems. Because it need not require the gradient of objective function and is easier to find global solution than gradient-based optimum algorithm using the gradient of objective function. However optimum method using the GA and the finite element method (FEM) takes many computational time to solve the optimum structural design problem which has a great number of design variables, constraints, and system with many degrees of freedom. In order to overcome the drawback of the optimum structural design using the GA and the FEM, the author developed a computer program which can optimize frame structures by using the GA and the generalized transfer stiffness coefficient method. In order to confirm the effectiveness of the developed program, it is applied to optimum design of plane frame structures. The computational results by the developed program were compared with those of iterative design.