• Title/Summary/Keyword: Generalized inverse

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Inverse behavior of IL-23R and IL-17RA in chronic and aggressive periodontitis

  • Ruiz-Gutierrez, Alondra del Carmen;Rodriguez-Montano, Ruth;Pita-Lopez, Maria Luisa;Zamora-Perez, Ana Lourdes;Guerrero-Velazquez, Celia
    • Journal of Periodontal and Implant Science
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    • v.51 no.4
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    • pp.254-263
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    • 2021
  • Purpose: Periodontitis is associated with a dysbiosis of periodontopathic bacteria, which stimulate the interleukin (IL)-23/IL-17 axis that plays an essential role in the immunopathogenesis of this disease, leading to alveolar bone destruction through receptor activator of nuclear factor κB ligand (RANKL). IL-23 receptor mRNA (IL-23R) has been identified in periodontitis, and IL-17 receptor A mRNA (IL-17RA) and its protein have not yet been evaluated in patients with periodontitis. In this study was measure IL-23R and IL-17RA in gingival tissue (GT) from patients with generalized chronic periodontitis (GCP) and generalized aggressive periodontitis (GAP) and to explore correlations with clinical parameters. Methods: We included 16 healthy subjects (HS), 18 patients with GCP, and 14 with GAP. GT samples were collected during periodontal surgery. Both IL-23R and IL-17RA were detected by enzyme-linked immunosorbent assay. Results: The results were analyzed with Mann-Whitney U test and Spearman' rank correlation coefficients using SPSS version 25.0. We found lower IL-23R levels in patients with GCP and GAP than in HS. Contrarily, we observed higher IL-17RA levels in GCP and GAP patients than in HS. Moreover, we found negative correlations between IL-23R in GT and probing depth and clinical attachment loss (CAL). Likewise, a positive correlation of IL-17RA in GT with CAL was found. Conclusions: The results of these findings suggest that the reverse behavior between IL-23R and IL-17RA in periodontitis patients may also be involved with the activation of RANKL, which promotes alveolar bone loss.

Model for Price Formation of Fish and Its Demand Structure (어류의 가격형성과 수요구조분석)

  • Park, Hoan-Jae
    • The Journal of Fisheries Business Administration
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    • v.40 no.1
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    • pp.133-152
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    • 2009
  • The purpose of this paper is to model price formation and analyze demand structures for fishes under the restriction of Korean fisheries regulations. This study suggests the model that the price of fish is formed by its quantity, expenditure, and habit persistence. In economic literature, such a fishery market demand is called the inverse demand with dynamic habit persistence. Based upon a static differential price formation model, the paper has generalized it dynamically incorporating habit persistence effects. The empirical results show that all the species have values less than one and (-) sign of price flexibilities, thus being price inflexible. The estimated habit adjustment coefficients are significant at the level of 1%. Especially, TAC species have the smaller values of them than those of other main fish species. The contribution and results are summarized as follows. First, the fishery market demand has a strong dynamic effects from habit persistence. Second, the fishery market demand structure could be analyzed in a way different from the ordinary demand analysis, which is based upon price flexibility, scale flexibility, and cross adjustment flexibility. Third, the limitation of this paper is that it ignores the increasing stock effects by catching restrictions, thus raising consumers' benefit in the future.

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Structural Homology Design Using Equality Constraints (등제한조건 함수를 이용한 구조물의 호몰로지 설계)

  • Lee, Gwon-Hui;Park, Gyeong-Jin
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.20 no.3
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    • pp.872-881
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    • 1996
  • The concept of homology design has been devised for the application to large telescope structure by S.v.Hoerner. It is defined that the deformation of a structure shall be called homologous, if a given geometrical relation holds, for a given number of structural points, before, during, and after the deformation. Recently, the need of homology design in the structural design has been increase due to the required precision in the structure. Some researchers have utilized the theory on the structural design with finite element method in the late 1980s In the present investigation, a simple method using geometrical equality constraints is suggested to gain homologous deformation. The previous method is improved in that the decomposition of FEM eqation, which is very expensive, is not necessary. The basic formulations of the homology design with the optimization concept are described and several practical examples are solved to verify the usefulness and validity. Especially, a back-up structure of a satellite antenna is designed by the suggested method. The results are compared with those of existing researches.

Investigating the Time Lag Effect between Economic Recession and Suicide Rates in Agriculture, Fisheries, and Forestry Workers in Korea

  • Yoon, Jin-Ha;Junger, Washington;Kim, Boo-Wook;Kim, Young-Joo;Koh, Sang-Baek
    • Safety and Health at Work
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    • v.3 no.4
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    • pp.294-297
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    • 2012
  • Previous studies on the vast increase in suicide mortality in Southeast Asia have indicated that suicide rates increase in parallel with a rise in unemployment or during periods of economic recession. This paper examines the effects of economic recession on suicidal rates amongst agriculture, fisheries, and forestry workers in Korea. Monthly time-series gross domestic product (GDP) data were linked with suicidal rates gathered from the cause of death records between1993-2008. Data were analyzed using generalized additive models to analyze trends, while a polynomial lag model was used to assess the unconstrained time lag effects of changes in GDP on suicidal rate. We found that there were significant inverse correlations between changes in GDP and suicide for a time lag of one to four months after the occurrence of economic event. Furthermore, it was evident that the overall relative risks of suicide were high enough to bring about social concern.

Design and Implementation of Electronic Approval System using Encryption (암호화를 이용한 전자결재 시스템의 설계 및 구현)

  • Jang, Young-Chul;Oh, Teh-Sok;Oh, Moo-Song
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.8
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    • pp.2060-2069
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    • 1997
  • Information processing using computer in generalized in the office automation. In spite of to be integrate and concise form of document through computer network, signature of document with hand have processed as ever. The security on document flow out severely unjust by reason of increment inverse function of computer. Because of revelation secret of enterprise result from unjust outflow, lots of loss of self-enterprise is occured. In this paper, we used efficiently document using the method, electronic approval system with encryption, for the resolving above problems. Also we persue maintenance of security for the important document and process document signature rapidly. Finally, we design and implementation of electronic approval system that take one's share of function between server and client using to be transformed Vernam's encryption technique in stored document.

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Simple factor analysis of measured data

  • Kozar, Ivica;Kozar, Danila Lozzi;Malic, Neira Toric
    • Coupled systems mechanics
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    • v.11 no.1
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    • pp.33-41
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    • 2022
  • Quite often we have a lot of measurement data and would like to find some relation between them. One common task is to see whether some measured data or a curve of known shape fit into the cumulative measured data. The problem can be visualized since data could generally be presented as curves or planes in Cartesian coordinates where each curve could be represented as a vector. In most cases we have measured the cumulative 'curve', we know shapes of other 'curves' and would like to determine unknown coefficients that multiply the known shapes in order to match the measured cumulative 'curve'. This problem could be presented in more complex variants, e.g., a constant could be added, some missing (unknown) data vector could be added to the measured summary vector, and instead of constant factors we could have polynomials, etc. All of them could be solved with slightly extended version of the procedure presented in the sequel. Solution procedure could be devised by reformulating the problem as a measurement problem and applying the generalized inverse of the measurement matrix. Measurement problem often has some errors involved in the measurement data but the least squares method that is comprised in the formulation quite successfully addresses the problem. Numerical examples illustrate the solution procedure.

Investigation of the Acceleration Coefficient in Acceleration Models (가속모델의 가속계수 조사)

  • Hyunjong Park;Sungjun Kim;Beomsik Park;Somi Park;Siil Sung
    • Journal of Korean Society for Quality Management
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    • v.52 no.1
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    • pp.135-148
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    • 2024
  • Purpose: This study is to investigate the literature on accelerated tests based on the acceleration model and to provide a compilation of results on the parameters applied in the acceleration model and the test conditions. Methods: This research is conducts a literature review on accelerated tests using the acceleration model, with a focus on test targets, test conditions, and parameter values. The study is organizing the results of this literature review to facilitate their application in the design of reliability tests. Results: A literature review investigated a variety of test targets, test conditions, and parameter values. Conclusion: The results of the literature research conducted revealed various acceleration model parameter. Such literature research on accelerated tests can establish the foundation for reliability test design and contribute to future product development and quality improvement

A Modeling Study on the AVO and Complex Trace Analyses of the Fracture Bone Reflection (파쇄대 반사에너지의 AVO 및 복소트레이스 분석에 관한 모형연구)

  • Han Soo-Hyung;Kim Ji-Soo;Ha Hee-Sang;Min Dong-Joo
    • Geophysics and Geophysical Exploration
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    • v.2 no.1
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    • pp.33-42
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    • 1999
  • AVO and complex trace analyses mainly used to characterize natural gas reservoir were tested in this paper for a possible application to detection of major geological discontinuities such as fracture zones. The test data used in this study were calculated by utilizing a viscoelastic numerical program which was based on the generalized Maxwell body for a horizontal fracture model. In AVO analysis of a horizontal fracture zone, p-wave reflection appears to be variant depending upon the acoustic-impedence contrast and the offset distance. The fracture zone is also effectively clarified both in gradient stack and range-limited stack in which fracture zone reflection is attenuated with the increasing offset distance. In complex attribute plots (instantaneous amplitude, frequency, and phase), the top and bottom of the fracture Tone are characterized by a zone of strong amplitudes and an event of the same phase. Low frequency characteristics appear at the fracture zone and the underneath. Amplitude attenuation and waveform dispersion are dependent on Q-contrast between the fracture zone and the surrounding media. They were properly compensated by optimum inverse Q-filtering.

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CONDITIONAL FOURIER-FEYNMAN TRANSFORMS AND CONVOLUTIONS OF UNBOUNDED FUNCTIONS ON A GENERALIZED WIENER SPACE

  • Cho, Dong Hyun
    • Journal of the Korean Mathematical Society
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    • v.50 no.5
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    • pp.1105-1127
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    • 2013
  • Let C[0, $t$] denote the function space of real-valued continuous paths on [0, $t$]. Define $X_n\;:\;C[0,t]{\rightarrow}\mathbb{R}^{n+1}$ and $X_{n+1}\;:\;C[0,t]{\rightarrow}\mathbb{R}^{n+2}$ by $X_n(x)=(x(t_0),x(t_1),{\ldots},x(t_n))$ and $X_{n+1}(x)=(x(t_0),x(t_1),{\ldots},x(t_n),x(t_{n+1}))$, respectively, where $0=t_0 <; t_1 <{\ldots} < t_n < t_{n+1}=t$. In the present paper, using simple formulas for the conditional expectations with the conditioning functions $X_n$ and $X_{n+1}$, we evaluate the $L_p(1{\leq}p{\leq}{\infty})$-analytic conditional Fourier-Feynman transforms and the conditional convolution products of the functions, which have the form $fr((v_1,x),{\ldots},(v_r,x)){\int}_{L_2}_{[0,t]}\exp\{i(v,x)\}d{\sigma}(v)$ for $x{\in}C[0,t]$, where $\{v_1,{\ldots},v_r\}$ is an orthonormal subset of $L_2[0,t]$, $f_r{\in}L_p(\mathbb{R}^r)$, and ${\sigma}$ is the complex Borel measure of bounded variation on $L_2[0,t]$. We then investigate the inverse conditional Fourier-Feynman transforms of the function and prove that the analytic conditional Fourier-Feynman transforms of the conditional convolution products for the functions can be expressed by the products of the analytic conditional Fourier-Feynman transform of each function.

A Study on the Method for Estimating the 30 m-Resolution Daily Temperature Extreme Value Using PRISM and GEV Method (PRISM과 GEV 방법을 활용한 30 m 해상도의 격자형 기온 극값 추정 방법 연구)

  • Lee, Joonlee;Ahn, Joong-Bae;Jeong, Ha-Gyu
    • Atmosphere
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    • v.26 no.4
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    • pp.697-709
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    • 2016
  • This study estimates and evaluates the extreme value of 30 m-resolution daily maximum and minimum temperatures over South Korea, using inverse distance weighting (IDW), parameter-elevation regression on independent slopes model (PRISM) and generalized extreme value (GEV) method. The three experiments are designed and performed to find the optimal estimation strategy to obtain extreme value. First experiment (EXP1) applies GEV firstly to automated surface observing system (ASOS) to estimate extreme value and then applies IDW to produce high-resolution extreme values. Second experiment (EXP2) is same as EXP1, but using PRISM to make the high-resolution extreme value instead of IDW. Third experiment (EXP3) firstly applies PRISM to ASOS to produce the high-resolution temperature field, and then applies GEV method to make high resolution extreme value data. By comparing these 3 experiments with extreme values obtained from observation data, we find that EXP3 shows the best performance to estimate extreme values of maximum and minimum temperatures, followed by EXP1 and EXP2. It is revealed that EXP1 and EXP2 have a limitation to estimate the extreme value at each grid point correctly because the extreme values of these experiments with 30 m-resolution are calculated from only 60 extreme values obtained from ASOS. On the other hand, the extreme value of EXP3 is similar to observation compared to others, since EXP3 produces 30m-resolution daily temperature through PRISM, and then applies GEV to that result at each grid point. This result indicates that the quality of statistically produced high-resolution extreme values which are estimated from observation data is different depending on the combination and procedure order of statistical methods.