• Title/Summary/Keyword: GeO

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Effects of selected phytochemicals and fruit extracts on Poly(ADP-ribose) polymerase (PARP) activity induced by H2O2 in MCF-7 breast cancer cells (식물생리활성물질과 과일류 추출물이 MCF-7 유방암 세포에서 H2O2로 유도된 Poly(ADP-ribose) Polymerase (PARP) 활성도에 미치는 영향)

  • Yoon, Hyungeun
    • Korean Journal of Food Science and Technology
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    • v.51 no.5
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    • pp.499-502
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    • 2019
  • Poly(ADP-ribose) polymerase (PARP) is a nuclear enzyme which is activated in response to DNA damage, and which mediates DNA repair. PARP inhibitors can be used to reduce resistance of cancer cells to anticancer treatments. The objective of this study was to investigate the effects of selected phytochemicals and fruit extracts on PARP activation in MCF-7 breast cancer cells subjected to oxidative stress. Pre-incubation with epigallocatechin gallate (EGCG), apple extract (AE), cranberry extract (CE), or grape extract (GE) for 2 hours at test concentrations reduced PARP activity induced upon treatment with hydrogen peroxide in a dose-dependent manner (p<0.05). GE was found to be the most efficient PARP inhibitor among the fruit extracts examined. These results suggest that phytochemicals of fruit extracts might be used as PARP inhibitors in order to assist anticancer agents.

Electron Mobility Model in Strained Si Inversion Layer (응력변형을 겪는 Si 반전층에서 전자 이동도 모델)

  • Park Il-Soo;Won Taeyoung
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.42 no.3 s.333
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    • pp.9-16
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    • 2005
  • The mobility in strained Si inversion layer on $Si_{1-x}Ge_x$ is calculated considering a quantum effect(subband energy and wavefunction) in inversion layer and relaxation time approximation. The quantum effect in inversion layer is obtained by using self-consistent calculation of $Schr\ddot{o}dinger$ and Poisson equations. For the relaxation time, intravalley and intervalley scatterings are considered. The result shows that the reason for the enhancement in mobility as Ge mole fraction increases is that the electron mobility in 2-폴드 valleys is about 3 times higher than that of 4-폴드 valleys and most electrons are located in 2-폴드 valleys as Ge mole fraction increases. Meanwhile, for the phonon-limited mobility the fitting to experimental data, Coulomb and surface roughness mobilities are included in total mobility, Deformation potentials are selected for the calculated effective field, temperature, and Ge mole fraction dependent mobilities to be fitted to experimental data, and then upgraded data can be obtained by considering nonparabolicity in Si band structure.

Preparasion and Characterization of Chalcogenide Glass with IR-Transmittance (적외 광투과 Chalcogenide계 유리의 제조 및 특성)

  • 송순모;최세영
    • Journal of the Korean Ceramic Society
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    • v.32 no.12
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    • pp.1424-1432
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    • 1995
  • Chalcogenide glasses having IR (8~12${\mu}{\textrm}{m}$) transmittance were prepared and their densities, thermal and mechanical properties, IR-transmittances and chemical durabilities were determined. Glass transition temperatures (Tg) of Ge-As-Se, Ge-As-Se-Te and Ge-SE-Te system glasses were in the range of 280~3$65^{\circ}C$, 210~236$^{\circ}C$ and 210~26$0^{\circ}C$, respectively. Crystallization temperature (Tc) of Ge-Se-Te system glass was in the range of 305~40$0^{\circ}C$. Their thermal expansion coefficients($\alpha$) were in the range of 11.7~15.2$\times$10-6/K, 15.4~16.0$\times$10-6/K and 17.4~27.8$\times$10-6/K, respectively. Their MOR, hardness and fracture toughness were in the range of 15.2~18.6MPa, 36.1~58.2Kg/$\textrm{mm}^2$, 1.0~1.3 MPa.mm1/2, 18.9~24.9 MPa, 40.9~65.1Kg/$\textrm{mm}^2$, 1.3~1.5 MPa.mm1/2, and 24.1~30.8 MPa, 40.9~86.0Kg/$\textrm{mm}^2$, 1.4~1.8 MPa.mm1/2, respectively. IR transmittance of Ge-Se-Te system glass was about 60%. Ge-O extrinsic absorption peaks at 8, 12 ${\mu}{\textrm}{m}$ were significantly eliminated by the addition of Mg. Chemical durabilities in deionizied water of Ge-Se-Te system glass were good and IR-transmittances decreased with leaching time and temperature.

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Growth of lead-based functional crystals by the vertical bridgman method

  • Xu Jiayue
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.16 no.1
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    • pp.1-7
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    • 2006
  • Some lead-based crystals show excellent ferroelectric, piezoelectric or scintillation properties and have attracted much attention in recent years. However, the erosion of the high temperature solution on platinum crucible and the evaporation of PbO component are the main problems often encountered during the crystal growth. In this paper, we reported recent progress on the Bridgman growth of lead-based functional crystals, such as novel relaxor ferroelectric crystals (PZNT and PMNT), scintillation crystals $(PbWO_4,\;PbF_2\;and\;PbClF)$ and piezoelectric crystals $(Pb_5Ge_3O_{11}\;and\;Pb_2KNb_5O_{15}),$ in Shanghai Institute of Ceramics, Chinese Academy of Sciences. The vertical Bridgman method has been modified to grow PZNT crystals from high temperature solution and as-grown crystals have been characterized. Large size lead-based scintillators, $PbWO_4\;and\;PbF_2$ crystals, have been mass-produced by the vertical Bridgman method in the multi-crucible fumace. These crystals have been supplied to CERN and other laboratories for high-energy physics experiments. The Bridgman growth of piezoelectric crystals $Pb_5Ge_3O_{11}\;and\;Pb_2KNb_5O_{15}$ are discussed also.

Uptake Properties of Germanium to Vegetable Plants and Its Effect on Seed Germination and on Early Stage Growth (채소종자 발아와 유묘생장에 미치는 유기 또는 무기게르마늄의 효과 및 흡수특성)

  • Han, Myung-Ja;Kim, Sung-Un;Seo, Dong-Cheol;Cheong, Yong-Hwa;Lee, Do-Jin;Park, Moon-Su;Rim, Yo-Sup;Sohn, Bo-Kyoon;Heo, Jong-Soo;Cho, Ju-Sik
    • Korean Journal of Environmental Agriculture
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    • v.26 no.3
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    • pp.217-222
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    • 2007
  • To investigate effects of inorganic $(GeO_2)$ and organic (Ge-132) germanium (Ge) on seed germination and on early stage growth of plane and the uptake characteristics, various concentrations (0, 10, 25, 50, 100 mg $L^{-1}$) of Ge to popular vegetables such as leaf mustard, chinese cabbage and pak-choi, respectively, were treated. On seed germination, no significant effect was observed in both inorganic and organic Ge treatments except 100 mg $L^{-1}$ treatment of inorganic Ge. Exogenous inorganic Ge ($10{\sim}100$ mg $L^{-1}$ treatments significantly inhibited the early root elongation growth of all plants. However, slight enhancement of early shoot elongation was detected in low concentrations (10 and 25 mg $L^{-1}$) of Ge in the leaf mustard and chinese cabbage plants. Organic Ge treatments significantly stimulated the 개ot and shoot growth at the 10, 25 and 50 mg $L^{-1}$ treatments. Ge was accumulated linearly in the vegetables as both inorganic and organic Ge concentrations were increased. Interestingly, total contents of Ge in plants with Ge-132 treatments were $2\sim4.5$ times more than those with inorganic Ge treatments in all concentrations. At 25 mg $L^{-1}$ treatment of Ge, contents of Ge in vegetables are following: in leaf mustard, inorganic Ge: 0.37 mg $g^{-1}dw$ and organic Ge: 1.47 mg $g^{-1}dw;$ in the chinese cabbage, inorganic Ge: 0.4 mg $g^{-1}dw$ and organic Ge: 0.86 mg $g^{-1}dw;$ in the pak-choi, inorganic Ge: 0.33 mg $g^{-1}dw$ and organic Ge: 0.70 mg $g^{-1}dw$, respectively. These results showed organic Ge is much better on early stage seedling growth and on germanium accumulation of vegetables than inorganic Ge.

Eine Studie $\"{u}ber$ zweisprachige Verbvalenzlexika (이중언어 동사 결합가 사전에 관한 연구)

  • Rhie Jum-Chool
    • Koreanishche Zeitschrift fur Deutsche Sprachwissenschaft
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    • v.1
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    • pp.11-39
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    • 1999
  • Das Ziel dieses Aufsatzes liegt darin, $da\ss$ wir eine Unterlage $f\"{u}r$ die Erarbeitung des kunftigen vergleichenden deutsch-koreanischen Verbvalenzlexikons bereitstellen, indem wir zweisprachige Valenz-lexika vergleichen, bei denen die Muttersprache der Lemenden als Ausgangssprache und die deutsche Sparche als Zielsprache fungieren, und ein neues Valenzmodell mit dem Verb 'kaufen 팔다' aufzeigen. Als Ergebnis dieser Arbeit $k\"{o}nnen$ wir feststellen, $da\ss$ die Entwicklung der kontrastiven Valenzlexikographie vom register-ahnlichen Lexikon hin zum benutzerfreundlichen $W\"{o}rterbuch$ $verl\"{a}uft$. Und ferner ist die Tendenz ansteigend, zweisprachige Versionen aus den einsprachigen $W\"{o}rterb\"{u}chern$ des Deutschen zu entwickeln, denn die kontrastiven $W\"{o}rterb\"{u}cher$ kommen den praktischen $Bed\"{u}rfnissen$ des Fremdsprachenunterrichts $f\"{u}r\;Anf\"{a}nger$ mehr entgegen als die einsprachigen. Die Valenzlexika sollten $prim\"{a}r$ dem Deutsch Lernenden helfen, seinen Wortschatz zu erweitern und korrekte $S\"{a}tze$ zu bilden, sollten jedoch nicht unmittelbares Selbststudienmaterial, sondern Nachschlagewerke sein. Die neuere Entwicklung in der Valenzlexikographie $f\"{u}hrt$ hin zum didaktisch orientierten $W\"{o}rterbuch$, in dem die $Valenzeintr\"{a}ge$ neben anderen syntaktischen und semantischen Informationen stehen. $F\"{u}r$ Studenten im Grundstudium sind $W\"{o}rterb\"{u}cher$ in der Fremdsprache zu schwierig. Bei der zweisprachigen Version erleichtern die $Valenzeintr\"{a}ge$ In der Muttersprache den Studierenden den Umgang mit dem $Lernw\"{o}rterbuch$. In Zukunft $k\"{o}nnen\;Valenzw\"{o}rterb\"{u}cher$ als wichtige Hilfsmittel im Fremd­sprachenunterricht noch an Bedeutung gewinnen. Ein $Valenzw\"{o}rterbuch$ ist vor allem ein $Produktionsw\"{o}rterbuch,\;denn\;es\;enth\"{a}lt$ syntaktisch-semantische Informationen und $Beispiels\"{a}tze$, die bei der Produktion korrekter Strukturen helfen. Das $Valenzw\"{o}rterbuch$ soll ein Nachschlagewerk, ein $Lernw\"{o}rter-buch$ zur weiteren Erforschung der syntaktish-semantischen Eigenschaften der deutschen Verben sein. Diese Untersuchung $\"{u}ber$ zweisprachige Verbvalenzlexika $k\"{o}nnte\;zur\;k\"{u}nfigen$ Erarbeitung des deutsch-koreanischen kontrastiven Verbvalenzlexikons beitragen.

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