• 대한한의진단학회지
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• 제12권1호
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• pp.103-130
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• 2008

Background: For standardizing of Han-Yeol [寒熱], which is a kind of diagnosis method in oriental medicine, it is necessary to investigate into relationship of symptoms and signs representative of Han-Yeol [寒熱] to the biofunctional medical signals; thermal temperature by Thermography, Pulse-Respiration Ratio and so on. By correlation analysis of these data items acquired from patients, it could be provides the fundamental data for standardizing of Han-Yeol [寒熱]. Objectives: We performed this study to check the characteristics of thermal temperature with Han-Yeol [寒熱] statue by pulse-respiration ratio. Methods: We selected nine regions around acupoints including Yin dang[印堂], Sugu[水溝, GV26], Ch'ondol[天突, CV22], Chonjung[CV17], Chung-wan[中脘, CV12], Chonchu[天樞 S25], No-gung[勞官, P8], and calculated based on the utility of R.O.I.(Region of Integer) by IR-2000 these points temperature from 68 subjects. In practicing pulse-respiration ratio over 4.0 means the statues of Yeol [熱], pulse-respiration ratio below 4.0 means the statues of Han [寒]. To optimum conditions thermal temperature, which are not effected by internal and external variables, we studied preceding research. The results shows that optimal time period is 20minutes after undressed and the optimal region is the region around acupoints including Sugu [水溝, GV26]. Based on a preceding research results, we analyzed these data by Paired T-test between GV26 Region and 8-Thermography Regions and two-way repeated ANOVA with thermography$({\Delta}T)$ and Han-Yeol [寒熱] statue by pulse-respiration ratio. Results: 1. In applying of two-way repeated ANOVA with thermography$({\Delta}T)$ and Han-Yeol [寒熱] statue by pulse-respiration ratio, Sugu [水溝穴, GV26] - [印堂穴, HN1], Sugu 水溝, GV26] - Chonjung[CV17], Sugu [水溝, GV26] -Chung-wan[中脘, CV12]had significant differences. 2. In applying of Paired T-test between Sugu [水溝穴, GV26] Region and 8- Thermography Regions, there were significant differences except of Sugu [水溝穴, GV26] -Chondolp[天突, CV22]. 3. In the difference of Sugu [水溝, GV26] -Chung-wan[中脘, CV12], thermal temperature increases a lot in the statues of Yeol [熱], thermal temperature decreases a lot in the statues of Han [寒]. Conclusions: On the analysis of Thermography, we obtain the measurement conditions were considered the individual variations. And it is different that the thermal temperature change on Thermography according to Han-Yeol [寒熱] statue by pulse-respiration ratio.

• 대한약침학회지
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• 제17권1호
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• pp.70-73
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• 2014

Objectives: Yamen is the fifteenth acupoint of the Governor Vessel Meridian (GV15). It is anatomically close to the medulla oblongata, so finding the safety depth of the acupoint is very important. However, few studies on the safety depth of GV15 have been done. Methods: This study tried to measure the safety depth of GV15 by using magnetic resonance imaging (MRI) scans and to analyze the factors affecting the safety depth through multiple regression analyses. This study was carried out for patients who had a brain MRI scan while visiting Jeonju Wonkwang Hospital, Korea. The shortest distance between the glabella and the occipital protuberance (DGO), the horizontal distance between the glabella and the back of the head (DGB) and the dangerous depth (DD) were measured from the sagittal views of the MRI images. The DD is the horizontal distance from the skin's surface at GV15 to the spinal dura mater. Results: The model suggested that the safety depth (SD) was significantly associated with gender (${\beta}$ = 0.474, P < 0.0001), DGO (${\beta}$ = 0.272, P = 0.027), and BMI (${\beta}$ = 0.249, P = 0.005) and the combination of three variables can explain the SD, with $R^2$ = 0.571 (Table 3). A longer SD was associated with males and with greater BMI and DGO. Conclusion: This study suggests that gender, BMI and DGO may be important factors when the SD of GV15 is considered clinically through a multiple regression analysis of GV15.

• 대한한방체열의학회지
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• 제8권1호
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• pp.18-25
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• 2010

Purpose : This study was performed to compare the characteristics of digital infrared thermographic imaging(DITI) in polycystic ovary syndrome(PCOS) patients with regulary cycling controls. Methods : We studied 19 patients visiting ${\bigcirc}{\bigcirc}$ korean hospital from 7th May 2010 to 8th January 2011. The subjects were categorized in two groups. 8 PCOS patients and 11 healthy regularly cycling controls. We investigated the difference of DITI between two groups by Mann-Whitney U-test using SPSS for window (version 17.0). Results : The average temperatures of five points(In-dang(EX-HN3), GV4, GV6, GV12, GV17) between PCOS and non-PCOS groups showed a little difference though p-value is not less than 0.05. The DITI differences of PCOS group between In-dang and thorax or between In-dang and abdomen showed lower than those of non-PCOS group though not a statistical significant level. Conculsion : The results suggest that DITI differences between PCOS and non-PC OS groups need to be developed to some degree for the diagnosis tool of PCOS.

• Imaging Science in Dentistry
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• 제53권4호
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• pp.365-373
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• 2023

Purpose: In the context of COVID-19, studies evaluating the adherence of dentists and dental students to infection control are relevant due to their high occupational exposure and risk, as well as their responsibility for disseminating information and good practices. This study evaluated the adherence of dentists and dental students to infection control in the oral radiology field in the setting of the COVID-19 pandemic on different continents. Materials and Methods: This cross-sectional observational study involved individuals who performed intraoral radiographic examinations during the COVID-19 pandemic. The Questionnaire on Infection Control in Oral Radiology was administered virtually using a Google Form. Participants from different continents(the Americas, Africa, Europe, Asia, and Oceania) were recruited. Data were subjected to descriptive analysis and simple and multiple binary regression (5%). Results: There were 582 valid answers, and 68.73% of the participants were from the Americas, 18.90% from Europe, and 12.37% from Asia. The median score for infection control protocols was 94 points for dental students and 104 points for dentists, and participants below the median were considered to have low adherence to infection control in oral radiology. Low access to infection control was found for 53.0% of dentists in the Americas, 34.0% from Europe, and 26.9% from Asia. Conclusion: The adherence to infection control protocols in oral radiology was low even in the face of the COVID-19 pandemic. The results may help improve the awareness of students and professionals, since oral radiology routines have the potential for transmitting COVID-19.

• 대한한의학방제학회지
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• 제31권3호
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• pp.157-169
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• 2023

Gracilaria Verrucosa (GV), a seaweed used in traditional Korean medicine, was studied for its effects on MI-induced heart failure in rats. MI is caused by a blocked coronary artery, leading to severe cardiac dysfunction. The study used a rat model to assess cardiac changes over time and evaluate the impact of GV on heart failure. Ischemia was induced through LAD ligation surgery, and the extent of ischemic area was measured as a prognostic factor. GV extract administration significantly improved cardiac morphology and reduced cardiac weight compared to the MI group. GV treatment also improved cardiac function, as evidenced by positive effects on chamber dilation during MI-induced heart failure. Parameters such as ejection fraction (EF) and fractional shortening (FS) were measured. The MI group showed decreased EF and FS compared to the sham group, while these parameters improved in the GV group. GV treatment also reduced levels of LDH, CPK, and CK-MB in the serum, indicating reduced myocardial damage. Histological analysis revealed that GV treatment attenuated cardiac hypertrophy and fibrosis, with reduced collagen deposition in the myocardium. Immunohistochemistry analysis showed suppressed expression of TGF-β1 and collagen 1, involved in fibrosis. In conclusion, GV showed potential in improving cardiac function in a rat model of MI-induced heart failure. It alleviated myocardial damage, attenuated cardiac hypertrophy and fibrosis, and suppressed fibrotic markers. Further studies are needed to explore its clinical efficacy and underlying mechanisms in cardiac diseases beyond animal models.

• 한국철도학회논문집
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• 제7권3호
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• pp.259-263
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• 2004

The running safety of a railway vehicle depends on the design parameters and contact condition between wheel and rail. In this study, the effect of the conicity of wheel tread is analyzed using ADAMS/RAIL software on running situation. Modal analysis shows in 0.6 Hz natural frequency of lateral mode in fully arranged the KTX cars. The excessive vibration of the tail cars occurs in the 17th car as the speed and the stiffness of the secondary suspension increases, and especially for 1/40 conicity of the GV40 wheel. Also, the analysis shows that combination of wheel profile, GV40 for power cars and XP55 for passenger cars can reduce the lateral vibration of the tail cars.

• 한국발생생물학회지:발생과생식
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• 제13권3호
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• pp.145-153
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• 2009

Previously, we obtained the list of genes differentially expressed between GV and MII oocytes. Out of the list, we focused on functional analysis of Zap70 in the present study, because it has been known to be expressed only in immune cells. This is the first report about the expression and its function of Zap70 in the oocytes. Synthetic 475 bp Zap70 dsRNA was microinjected into the GV oocytes, and the oocytes were cultured in vitro. In addition to maturation rates, meiotic spindle and chromosome rearrangements, and changes in expression levels of transcripts of three kinases, Erk1/2, JNK, and p38, were determined. Zap70 is highly expressed in immature GV oocytes, and gradually decreased as oocyte matured. When dsRNA of Zap70 was injected into the GV oocytes, Zap70 mRNA specifically and completely decreased by 2 hr and its protein expression also decreased significantly. Absence of Zap70 resulted in maturation inhibition at meiosis I (57%) with abnormalities in meiotic spindle formation and chromosome rearrangement. Concurrently, mRNA expression of Erk2, JNK, and p38, were affected by Zap70 RNAi. Therefore, we concluded that Zap70 is involved in MI-MII transition by affecting expression of MAP kinases.

• Journal of Positioning, Navigation, and Timing
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• 제1권1호
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• pp.65-75
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• 2012

We carry out an error analysis of 24-hour global positioning system (GPS)-very long baseline interferometry (VLBI) (GV) hybrid observation data. In this paper, we focus on the impacts of broadcast and final orbits on the GPS delays of the GV hybrid observation by analyzing the residuals, observed - calculated (O-C) values. The residuals show apparent and consistent biases for L1 and L2 signals, respectively. The scatters of the residuals are around a few nanoseconds. The main cause of those observation errors is the absence of the GPS phase and delay calibration system. Most of the satellites show that the differences between the delays, to which broadcast and final orbits are applied, are about 100 times smaller than the current GV hybrid observation errors. We conclude that GPS delays are not greatly affected by orbit accuracies.

• Journal of Acupuncture Research
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• 제19권6호
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• pp.24-34
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• 2002

Objective : To report seborrheic dermatitis of the scalp which is treated by Bee-venom Acupuncture therapy. Methods : Under the assumption that Be-venom Therapy may be effective for treatment seborrheic dermatitis, Bee-venom acupuncture was injected subcutaneously into the lesion including Gv24(神庭), Gv23(上星), Gv22, Gv20(白會), B4(曲差), B5(五處), B6(承光), S8(頭維), etc. Results : The symptoms including erythematous plaque, scale, itching were resolved clearly except a little scale by Bee-venom acupuncture Therapy. Conclusions : Bee-venom acupuncture Therapy is effective in the treatment of seborrheic dermatitis. if more clinical trials like this are proved to be effective in seborrheic dermatitis, we can expect that Bee-venom acupuncture Therapy is used to treatment of seborrheic dermatitis as good method.

• 한국산학기술학회논문지
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• 제10권6호
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• pp.1407-1413
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• 2009

본 연구에서는 쥐의 미성숙 난자의 체외 성숙과정에서 매우 특이적으로 발현되는 후보 단백질 변화를 동정하려는 목적으로 체외 성숙 과정에서 GV 단계의 미성숙 난자와 MIl 단계의 난자를 실험 시료로 사용하였다. 그리고 단백질 Chip은 선행 실험에서 가장 효과적인 CM10을 사용하여 SELDI -TOF MS 분석 장치를 이용하여 후보단백질을 동정하였다. MIl 단계의 미성숙 난자와 비교하여 GV 단계의 미성숙 난자에서 16개의 후보단백질이 높게 발현되었으며, 이때 발현된 후보 단백질 각각의 분자량은 8180(후보단백질 2개), 10226 (5개), 15767(5개), 16770(4개) 달톤(dalton)이였다. 또한 29개의 후보단백질은 MIl 단계의 미성숙 난자에서 높게 발현되었고 이들의 분자량은 각각 10832(3개)17743(8개)20122(3개)22131(3개) 24857(7개) 33507(5개) 달톤 이였다. 한편 전체 후보 단백질 45개의 분석을 Real time RT-PCR에서 수행하여 13개의 잠재적인 후보단백질을 확인 동정하였다.