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Limb Salvage Operation with Recycled Autogenous Bone Graft (자가골 재이식술을 이용한 사지 구제술)

  • Rhee, Seung-Koo;Kang, Yong-Koo;Suh, Yoo-Joon;Yoo, Jong-Min;Jung, In-Ho
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.2
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    • pp.96-106
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    • 2004
  • Purpose: To determine the usefulness of limb salvage operation with recycled autogenous bone graft in musculoskeletal malignant tumors. Materials and Methods: Twenty nine cases, who underwent limb salvage operation with recycled autogenous bone graft for the treatment of musculoskeletal malignant tumor between February 1990 and January 2003, were included. There were 18 males and 11 females and the mean age was 33 years (range, 10 to 65 years). The mean follow-up period was 51.8 months (range, 18 to 117 months). The Enneking stage was IIA in 10 cases and IIB in 19 cases. The recycling method of autogenous bone was deep freezing in 6 cases, autoclaving in 11 cases, pasteurization in 7 cases and the composite of autoclaving and vascularized fibular graft in 5 cases. The union of junctional site was evaluated radiologically and the functional results was analyzed by the grading systems of the International Symposium On Limb Salvages (ISOLS). Results: The mean union time was 7.2 months (range, 3 to 15 months). The union took 5.8 months (range, 4 to 8 months) in deep freezing, 9.7 months (range, 6 to 15 months) in autoclaving, 5.9 months (range, 4 to 8 months) in pasteurization, and 5 months (range, 4 to 8 months) in the composite of autoclaving and vascularized fibular graft. The mean functional evaluation percentage was 76.8% (range, 40 to 90%). It was 65.8% (range, 40 to 85%) in deep freezing, 76.6% (range, 40 to 90%) in autoclaving, 81.6% (range, 70 to 90%) in pasteurization, and 83.4% (range, 75 to 90%) in the composite of autoclaving and vascularized fibular graft. There were 6 cases of complications including 1 case of local recurrence, lung metastasis, infection, fracture, respectively and 2 cases of nonunion. Conclusion: The limb salvage operation with recycled autogenous bone graft is a useful treatment method for the musculoskeletal malignant tumors. Particularly, autoclaving is the most reliable sterilization method. The vascularized fibular graft can compensate decreased osteoinductivity and mechanical strength of recycled bone. So, the composite of autoclaving and vascularized bone graft seems to be a favorable treatment method for high grade malignant musculoskeletal tumors.

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The Effects of Object Size and Reaching Distance on Upper Extremity Movement (물체 크기와 뻗기 거리가 상지 움직임에 미치는 영향)

  • Bae, Su-Young;Kim, Tae-Hoon
    • The Journal of Korean society of community based occupational therapy
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    • v.10 no.1
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    • pp.51-61
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    • 2020
  • Objectives : The purpose of this study is to investigate the effect of object size and reaching distance on kinematic factors of the upper limb while performing arm reaching for normal subjects. Methods : The subjects of this study were 30 university students who were in D university in Busan, and the measuring tool was CMS-70P(Zebris Medizintechnik Gmbh, Germany), a three-dimensional motion analyzer. The task had six conditions. The average velocity of motion, average acceleration, maximum velocity, and the velocity definite number of movements were measured according to changes in object size(2cm, 10cm) and reaching distance(15%, 37.5%, 60%) when they performed arm reaching. The general characteristics of the subject were technical statistics. One-way ANOVA measurement was used to compare variables when the arm reaching task was performed from two object sizes to three reaching distance, and the post-test was conducted with Tukey test. In addition, an independent t-test was used to analyze the kinematic differences according to the two object sizes at three reaching distances. A two-way ANOVA measurement (3×2 Two-way ANOVA measurement) was performed to identify the interaction of the reaching distance(15%, 37.5%, 60%) and the object size(2cm, 10cm). The statistical significance level α was set to .05. Results : When the size of the object increased, the velocity and maximum velocity also increased, but the definite number of velocity decreased. When the reaching distance increased, the velocity and maximum velocity increased, whereas the definite number of velocity decreased. Conclusion : The clinical significance of this study could be utilized as the baseline data for grading object size and reaching distances when the reaching training is implemented for patients whose central nervous system was damaged.

Analysis of the Domestic Consumer's Preference and Consumption Behaviors on Pork (국내 소비자의 돼지고기 선호도와 소비행태 분석)

  • Kim, Gye-Woong;Kim, Seok-Eun
    • Journal of Animal Science and Technology
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    • v.51 no.1
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    • pp.81-90
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    • 2009
  • This study was carried out to investigate consumer's preference and purchase behavior of pork including perception of brand-pork in Korea. A total of 504 respondents were surveyed and collected from December, 2007 to February, 2008. Among total respondents, 62.55% (n=314) responded that they liked the pork and respondents who were higher education level showed higher preference (p<0.05). Majority of consumers (61.16%) did not like imported pork. In addition, one who had lower education level and living in rural area disliked more the imported pork. Most consumers preferred to the belly (58.57%) and results indicated that the people who were higher education level preferred a discount mart but who were living in rural area preferred a butcher's shop. Among the purchasing area, a big discount mart was the most preferred (44.64%) and this was also different among the education level (p<0.001) and living areas (p<0.05). The consumers preferred to purchasing a 600 g pack for a single purchase. Among total respondents, 42.71% of consumers responded that their priority was reliability of meat quality on choosing the place for purchasing the pork, and the significant difference was highly found in living area groups (p<0.001). The perception of carcass grading system was common scores with the average of 2.79, and there was highly significant difference among education level groups (p<0.001). The average of 3.50 among 5 points for branded pork were evaluated by a total of consumers but the significant differences were not found in all three groups.

The Effect of Body Measurements Type on Carcass Traits in Hanwoo (한우의 체형형질이 도체형질에 미치는 영향)

  • Sun, Du-Won;Kim, Byeong-Woo;Park, Jong-Won;Moon, Won-Gon;Choo, Hyo-Jun;Jeon, Jin-Tae;Lee, Jung-Gyu
    • Journal of Animal Science and Technology
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    • v.50 no.6
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    • pp.763-774
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    • 2008
  • This study was carried out to investigate the correlation of body measurement type and carcass traits. This study used body measurement type and carcass traits on 1,312 heads of Hanwoo steers tested(24 months) which was from 1997 to 2002 at Hanwoo Improvement Main Center National Agricultural Cooperatives Federation. Body measurement type used the age of 18 months body measurement type, and carcass traits used the results of decision grade of Animal Products Grading Service. Observing the phenotypic correlation between carcass traits and body measurement type from the result, the weight, withers height, and chest width at age of 18 months and carcass weight showed readings of 0.690, 0.483, and 0.506, respectively. Also, eye muscle area and age of 18 months weight and chest width read 0.356 and 0.279, respectively. According to results, that improvements in weight, withers height, and chest width are likely to enlarge the eye muscle area and meat production level. Not only quality improvement but also quantity augmentation affect income and sales of the farmers. As can be seen in this study, improvements of weight, withers height and chest width should always be put to much effort while other body measurement type should be considered continuously too. In order to attain clearer results further studies should be done on body measurement type, which will contribute to the improvements of body measurement type in Hanwoo.

Reproducibility of the Assessment of Myocardial Function Using Gated Tc-99m-MIBI SPECT and Quantitative Software (게이트 Tc-99m-MIBI SPECT와 Cedars 소프트웨어를 이용한 심근 기능 측정의 재현성)

  • Lee, Dong-Soo;Cheon, Gi-Jeong;Ahn, Ji-Young;Chung, June-Key;Lee, Myung-Chul
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.5
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    • pp.403-413
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    • 1998
  • Purpose: We investigated reproducibility of the quantification of left ventricular volume and ejection fraction, and grading of myocardial wall motion and systolic thickening when we used gated myocardial SPECT and Cedars quantification software. Materials and Methods: We performed gated myocardial SPECT in 33 consecutive patients twice in the same position after Tc-99m-MIBI SPECT We used 16 frames per cycle for the gating of sequential Tc-99m-MIBI SPECT. After reconstruction, we used Cedars quantitative gated SPECT and calculated ventricular volume and ejection fraction (EF). Wall motion was graded using 5 point score. Wall thickening was graded using 4 point score. Coefficient of variation for re-examination of volume and fraction were calculated. Kappa values (k-value) for assessing reproducibility of wall motion or wall thickening were calculated. Results: Enddiastolic volumes (EDV) ranged from 58 ml to 248 ml (122 ml +/- 42 ml), endsystolic volumes (ESV) from 20 ml to 174 ml (65 ml +/- 39 ml), and EF from 20% to 65% (51% +/- 14%). Geometric mean of standard deviations of 33 patients was 5.0 ml for EDV, 3.9 ml for ESV and 1.9% for EF. Their average differences were not different from zero (p>0.05). k-value for wall motion using 2 consecutive images was 0.76 (confidence interval: 0.71-0.81). k-value was 0.87 (confidence interval: 0.83-0.90) for assessment of wall thickening. Conclusion: We concluded that quantification of functional indices, assessment of wall motion and wall thickening using gated Tc-99m-MIBI SPECT was reproducible and we could use this method for the evaluation of short-acting drug effect.

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Usefulness of $^{99m}Tc$-MDP Bone Scintigraphy for Assessing Vascular Ingrowth on Hydroxyapatite Ocular Implant ($^{99m}Tc$-MDP 골신티그라피를 이용한 Hydroxyapatite 안구 보충물의 혈관 신생 평가 및 임상적 유용성)

  • Kang, Bong-Joo;Sohn, Hyung-Sun
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.6
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    • pp.484-492
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    • 1999
  • Purpose: This study was to evaluate the clinical usefulness of $^{99m}Tc$-MDP bone scintigraphy for assessing vascular ingrowth into the ocular implants after enucleation or evisceration. Materials and Methods: Twenty-four patients (M:F=7:17, mean age: 36 years), who buried a coralline hydroxyapatite after uncomplicated enucleation or evisceration surgery were studied. Dynamic and static scintigraphy on the orbit fossa were obtained after injection of 740 MBq $^{99m}Tc$-MDP to evaluate the status of vascularization. The study was performed from the 3 to 33 weeks after surgery. According to the visual analysis, activity greater than nasal bridge was graded as 4, equal to the nasal bridge as 3, less than nasal bridge but greater than normal orbit as 2, greater than normal orbit but less than grade 2 as 1. Uptake ratio was also calculated by measuring the implants activity (H) and contralateral orbit activity (N). Grading score and uptake ratio were compared with clinical outcome of vascularization. Additionally, we also analyzed the vascularization status as time lapse between primary surgery and scintigraphic study and surgical methods. Results: Twenty-one patients who had bone scintigraphy at 11 weeks after surgery showed increased uptake above grade 2 and greater H/N ratio than 1.16. Of these, 19 patients who had drilling surgery for permanent peg application showed adequate bleeding during the procedure. The activity grade and uptake ratio were inversely correlated with vascular ingrowth. Higher than grade 2 or greater than 1.56 in H/N ratio seemed to be an indicator for better prognosis. Accomplishment of vascularization was not affected by the surgical way such as enucleation or evisceration. Conclusion: $^{99m}Tc$-MDP bone scintigraphy can be a useful method to evaluate the vascularized status of implants. Adequate time for $^{99m}Tc$-MDP bone scintigraphy may be 11-20 weeks after enucleation or evisceration.

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Morphologic Follow-Up of the Anastomotic Sites Using One-year and Five-year Angiography after Coronary Artery Bypass Grafting (관상동맥우회술 후 1년 및 5년 추적 관상동맥조영술을 이용한 문합부위의 형태학적 변화)

  • Cho Kwang Ree;Kim Jun-Sung;Choi Jae-Sung;Chae In-Ho;Oh Byung-Hee;Lee Myoung-Mook;Park Young-Bae;Kim Ki-Bong
    • Journal of Chest Surgery
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    • v.38 no.3 s.248
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    • pp.191-196
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    • 2005
  • We analysed the characteristics of anastomotic sites after coronary artery bypass grafting (CABG) using coronary angiographies (CAGs) performed at one and five years postoperatively in the same patient population. Material and Method: Among the 219 patients who underwent isolated CABGs between January 1995 and December 1997, follow-up coronary angiograms were performed in 149 ($75.3\%$) patients at one year and in 115 ($58.1\%$) patients at five years postoperatively. FitzGibbon grading system was used to evaluate the anastomotic sites. Result: The patency rates of arterial grafts at one- and five-year were $96.5\%$ (192/199) and $93.1\%$ (134/144), which were higher than those of saphenous vein grafts (SVGs) ($82.9\%$ (224/270) and $77.5\%$ (141/182), respectively) (p=0.01). Although there were significant decreases in the patency rates between one- and five-year CAGs of both arterial and venous grafts, the proportion of FitzGibbon grade B among the SVGs was increased from $5.2\%$ (one-year) to $8.2\%$ (five-year), suggesting the progression of vein graft disease (p < 0.01). Conclusion: The patency rate of the arterial graft was higher than that of SVG in both one- and five-year CAGs. The attrition rate of saphenous vein graft was higher than arterial grafts.

Genetic Parameter Estimation of Carcass Traits of Hanwoo Steers (한우 거세우의 도체형질에 대한 유전모수 추정)

  • Hwang, Jeong-Mi;Kim, Sidong;Choy, Yun-Ho;Yoon, Ho-Baek;Park, Cheol-Jin
    • Journal of Animal Science and Technology
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    • v.50 no.5
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    • pp.613-620
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    • 2008
  • The genetic parameters used in National Hanwoo Genetic Evaluation(NHGE) were needed to be monitored and updated periodically for accounting any possible changes in population parameters due to selection and environmental changes. Genetic parameters were estimated with single and two-trait models with MTDFREML package using 2,791 carcass records of steers collected from Hanwoo Progeny Test Program(HPTP). Single and two-trait models gave similar parameter estimates for all traits. The heritability estimates from single and two-trait models for carcass weight(CW), dressing percentage(DP), eye muscle area(EMA), back fat thickness(BFT) and marbling score(MS) were 0.30, 0.30, 0.37, 0.44 and 0.44, respectively. The heritability estimates for all the traits except BFT were slightly lower than those used in NHGE but seemed to be within the acceptable ranges. However, further monitoring is needed because the data might not have fully reflected the changes such as carcass grading standards in performance testing program. In order to shift statistical model of NHGE from single trait model to multiple-trait model, the genetic correlations between carcass traits were estimated with pairwise two-trait models. The genetic correlation coefficients between CW and DP, between CW and EMA, between CW and BFT and between CW and MS were 0.44, 0.63, 0.17 and 0.06, respectively. Those between DP and EMA, between DP and BFT and between DP and MS were 0.29, 0.40 and 0.20. Those between EMA and BFT and between EMA and MS were -0.24 and 0.15, respectively. The genetic correlation coefficient between BFT and MS was 0.03.

Preventive Measures on Alkali-Silica Reaction of Crushed Stones (쇄석 골재의 알칼리-실리카 반응 방지 대책)

  • Jun Ssang-Sun;Lee Hyo-Min;Seo Ki-Young;Hwang Jin-Yeon;Jin Chi-Sub
    • Journal of the Korea Concrete Institute
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    • v.17 no.1 s.85
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    • pp.129-137
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    • 2005
  • In Korea, due to the insufficiency of natural aggregates and increasing needs of crushed stones, it is necessary to examine the alkali-silica reaction of the crushed stones. The reaction produces an alkali-silica reaction gel which can imbibe pore solution and swell to generate cracks that are visible In affected concrete. In general, crushed stones are tested by petrograptuc examination, chemical method and mortar-bar method, but the most reliable method Is mortar-bar test. This study tested alkali-silica reactivity of crushed stones of various rock types using ASTM C 227 and C 1260, and compared the results of two test methods. This study also analyzed effects of particle size and grading of reactive aggregate on alkali-silica reaction expansion of mortar-bar. The effectiveness of mineral admixtures to reduce detrimental expansion caused by alkali-silica reaction was investigated through the ASTM C 1260 method. The mineral admixtures used were nv ash, silica fume, metakaolin and ground granulated blast furnace slag. The replacement ratios of 0, 5, 10, 15, 25 and $35\%$ were commonly applied for all the mineral admixtures and the replacement ratios of 45 and $55\%$ were additional applied for the admixtures that could maintain workability. The results indicate that replacement ratios of $25\%$ for ay ash, $10\%$ for silica fume, $25\%$ for metakaolin or $35\%$ for ground granulated blast furnace slag were most effective to reduce alkali-silica reaction expansion under the experimental conditions.

The Influence of Fineness Modulus of Pine Aggregate and Grain Shape of Coarse Aggregate on the Properties of High Flowing Concrete (잔골재 조립률 및 굵은골재 입형이 초유동 콘크리트의 특성에 미치는 영향)

  • Jung Yong-Wook;Lee Seung-han;Yun Yong-Ho
    • Journal of the Korea Concrete Institute
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    • v.17 no.5 s.89
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    • pp.785-792
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    • 2005
  • This study is to examine the influence of defective grain shape of coarse aggregate and lowered fineness modulus of fine aggregate on the characteristics of high flowing concrete. The flow ability and compact ability of high flowing concrete was examined using fine aggregate, varying its fineness modulus to 2.0, 2.5, 3.0, and 3.5, and coarse aggregate with before and after grain shape improvement. Also the influence of fineness modulus of fine aggregate and grain shape of coarse aggregate on dispersion distance of particles of aggregate was examined by relatively comparing the dispersion distance between particles of aggregate. According to the experimental result, minimum porosity when mixing fine aggregate and coarse aggregate was shown in order of fineness modulus of fine aggregate, 3.0, 2.5, 2.0, 3.5, regardless of the improvement of grain shape. So when the fineness modulus is bigger or smaller than KS Standard $2.3\~3.1$, the porosity increased. When the spherical rate of the grain shape of coarse aggregate unproved from 0.69, a disk shape to 0.78 sphere shape, the rate of fine aggregate, which represents minimum porosity, decreased $6\%$ from $47\%\;to\;41\%$. The 28 days compressive strength according to fineness modulus of fine aggregate increased about 3 ma as the fineness modulus increased from 2.0 to 2,5, and 3.0. However, the 28 days compressive strength decreased about 9 ma at 3.5 fineness modulus as compared with 3.0 fineness modulus. The improvement of grain shape in coarse aggregate and increase of fineness modulus in fine aggregate made the flow ability, compact ability, and V-rod flowing time improve. Also the fineness modulus of fine aggregate increased the paste volume ratio when a higher value was used within the scope of KS Standard $2.3\~3.1$.