• Journal of the Society of Naval Architects of Korea
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• v.36 no.1
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• pp.99-108
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• 1999

The solid modelling program was developed for the 3-D representation and analysis of VEry High-rise Steel Artificial Reefs(VEHSAR) using Visual C++ on the Microsoft's Windows 95(or Windows NT) based on MFC(Microsoft Foundation Class). Importing oriented-object program and CAD/CAM technique, this integrated design system which aims at low cost and high efficiency makes it possible to predict problems and to establish counterplans through visualizing the construction of Very High-rise Steel Artificial Reefs in advance. Also it is useful in enhancing productivity. Introduction of OpenGL makes it display high quality 3D graphics more faster.

• Proceedings of the Korea Concrete Institute Conference
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• 2009.05a
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• pp.309-310
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• 2009

This study was performed as the first step of concrete materiaI research(concrete test program)of Lotte Super Tower column shortening research. Total 18 month's creep and shrinkage results were obtained from the test so far. The analysis were conducted using those results by design strength and loading age, and then validated model and equation were proposed from the result analysis and regression analysis. AC I209R Model, Bazant-Baweja B3 Model, CEB MC99 Model, & GL2000 Model, were employed for this study. The main analysis was completed on the total shrinkage strain and compliance.

• The Korean Journal of Physiology and Pharmacology
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• v.5 no.6
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• pp.457-466
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• 2001

Glutamate is the most common excitatory amino acid in the brain. Responsiveness of dendrites to the glutamate greatly varies depending on the application sites. Especially, a point of the maximal response to the glutamate of the dendrite is called as 'hot spot'. In our experiment, the responsiveness of the hot spot to the glutamate was investigated in the CA1 pyramidal neuron of the rat hippocampal slice. CNQX, the antagonist of AMPA receptor, blocked 95% of membrane current to the glutamate focal application $(I_{gl}).$ Train ejection of glutamate on one point of the dendrite increased or decreased the amplitude of $I_{gl}$ with the pattern of train, and the changes were maintained at least for 30 min. In some cases, glutamate train ejection also induced calcium dependent action potentials. To evoke long-term change of synaptic plasticity, we adopted ${\theta}-burst$ in the glutamate train ejection. The ${\theta}-burst$ decreased the amplitude of glutamate response by 60%. However, after ${\theta}-burst$ glutamate train ejection, the calcium dependent action potential appeared. These results indicated that the focal application of glutamate on the neuronal dendrite induced response similar to the synaptic transmission and the trains of glutamate ejection modulated the change of AMPA receptor.

• Bulletin of the Korean Chemical Society
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• v.16 no.5
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• pp.401-406
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• 1995

The P. fragi lipase overexpressed in E. coli as a fusion protein of 57 kilodalton (kDa) has been purified through glutathione-agarose affinity chromatography by elution with free glutathione. The general properties of the purified GST-fusion protein were characterized by observing absorbance of released p-nitrophenoxide at 400 nm which was hydrolyzed from the substrate p-nitrophenyl palmitate. The optimum condition was observed at 25 $^{\circ}C$, pH 7.8 with 0.4 ${\mu}g$ of protein and 1.0 mM substrate in 0.6% (v/v) TritonX-100 solution. Also the lipase was activated by Ca+2, Mg+2, Ba+2 and Na+ but it was inhibited by Co+2 and Ni+2. pGEX-2T containing P. fragi lipase gene as expression vector was named pGL191 and used as a template for the site-directed mutagenesis by sequential PCR steps. A Ser-His-Asp catalytic triad similar to that present in serine proteases may be present in Pseudomonas lipase. Therefore, the PCR fragments replacing Asp217 to Arg and His260 to Arg were synthesized, and substituted for original fragment in pGL19. The ligated products were transformed into E. coli NM522, and pGEX-2T harboring mutant lipase genes were screened through digestion with XbaI and StuI sites created by mutagenic primers, respectively. No activity of mutant lipases was observed on the plate containing tributyrin. The purified mutant lipases were not activated on the substrate and affected at pH variation. These results demonstrate that Asp217 and His260 are involved in the catalytic site of Pseudomonas lipase.

• Korean Management Science Review
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• v.9 no.1
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• pp.41-52
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• 1992

The QOS(Quality of Service) recognized by the customer will become the most important thing under the competitive telecommunications market. Korea Telecom is going to develop many system to manage the telecommunication network, to improve the level of QOS, and to increase the revenue. Operation and Maintenance Adiministration System is one of the systems developed to meet those purposes efficiently. This system gathers qualities data from telephone offices or operation centers and analyze the results of QOS improvement activities and evaluate overall QOS. And also system makes it possible to improve the cost/effectiveness of operation and maintenance of telecommunication network. Operation and Maintenance Administration System has four functional modules, i.e., the user interface module, the database management module, the QOS management module, and the database conversion module. The purpose of this study is to develop the QOS management program, one of the four functional modules of the system,using FOCUS 4GL/DBMS. Since Operation and Maintenance Administration System is developed using FOCUS 4GL, every user can handle and maintain the system very easily and reduce system backlogs.

• Journal of Mechanical Science and Technology
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• v.15 no.7
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• pp.889-894
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• 2001

In this study, the performances of various turbulence closure models are evaluated in the calculation of a transonic flow over axisymmetric bump. k-$\varepsilon$, explicit algebraic stress, and two Reynolds stress models, i.e., GL model proposed by Gibson & Launder and SSG model proposed by Speziale, Sarkar and Gatski, are chosen as turbulence closure models. SSG Reynolds stress model gives best predictions for pressure coefficients and the location of shock. The results with GL model also show quite accurate prediction of pressure coefficients down-stream of shock wave. However, in the predictions of mean velocities and turbulent stresses, the results are not so satisfactory as in the prediction of pressure coefficients.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.58 no.2
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• pp.221-226
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• 2009

In this paper, we analyzed form of flowing leakage current in electrical installation. Leakage current ($I_g$) is consisted of resistive leakage current($I_{gr}$), capacitive leakage current($I_{gc}$), and inductive leakage current($I_{gl}$). Resistive leakage current($I_{gr}$) is big occasion than capacitive leakage current($I_{gc}$) in system, Residual Current Protective Device(RCD) detects correctly leakage current. But,$I_{gc}$ is big occasion than $I_{gr}$, RCD is malfunctioned It is resistance to lead to electric fire in electrical device. We manufactured outlet that resistive leakage current detecting circuit is had. Manufactured outlet displayed performance exactly in leakage current of 5 mA Therefore, this product estimates that contribute on electric fire courtesy call.

• Proceedings of the KIEE Conference
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• 2008.09a
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• pp.301-304
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• 2008

In this paper, we study from of flowing leakage current in electrical installation. Leakage current is expressed by a resistivity leakage current($I_{gr}$), a capacitive leakage current($I_{gc}$), an inductivity leakage current($I_{gl}$). General Zero Phase Current Transformer (ZCT) detect a leakage current($I_{g}$) that are conjoined resistivity leakage current and capacitive leakage current. In case $I_{gr}$ is big than $I_{gc}$, there is no singular problem in leakage current detection of system. But, in case $I_{gc}$ is big than $I_{gr}$, earth leakage breaker can not prevent accident effectively. Can lower electric leakage perception current to 5 mA if apply resistivity leakage current detecting circuit. We can achieve prevention of electricity disaster spontaneously.

• Journal of Digital Contents Society
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• v.15 no.2
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• pp.197-207
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• 2014

Many people are now enjoying mobile games using various smartphone platforms. However, we have to develop games separately for each smart device platforms so far. Cocos2d-x, a game development framework is released to solve this problem. As a multiplatform version of the existing Cocos2d, Cocos2d-x can make one source code run on various platforms. It is an open software that is able to be used by everyone, and when using it, mobile games can be developed easily based on C++ and OpenGL. In this paper, we implemented a PC laboratory decorating game application, named ILove501, using Cocos2d-x. The 501 is a room number of our PC lab. ILove501 includes an educational feature of solving quizzes in order to highlight positive effects of game. For implementation of a multiplatform game, ILove501 was developed in Windows and iOS environment at the same time, and we verified the results of the execution by porting on a variety of devices such as Android, iPhone, iPad and Galaxy Tab.

• Journal of Life Science
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• v.12 no.4
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• pp.469-476
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• 2002

The DNA topoismerase I inhibitor $\beta$-lapachone, the product of a tree from South America, is known to exhibit various biological properties, however the mechanisms of which are poorly understood. In the present report, we investigated the effects of $\beta$-lapachone on the growth of human prostate carcinoma DU-145 cells. Upon treatment with $\beta$-lapachone, a concentration-dependent inhibition of cell viability was observed and cells developed many of the hallmark features of apoptosis, including condensation of chromatin and DNA fragmentation. Flow cytometry analysis confirmed that $\beta$-lapachone increased populations of apoptotic-sub Gl phase. In addition, proteolytic cleavages of poly (ADP-ribose) polymerase (PARP) and $\beta$-catenin protein were observed after treatment of $\beta$-lapachone. These apoptotic effects of $\beta$-lapachone in DU-145 cells were associated with marked induction of Bax protein, however the levels of Bcl-2 expression were decreased in a dose-dependent manner.