• Journal of Aerospace System Engineering
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• v.13 no.5
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• pp.1-8
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• 2019

Recently, avionics has been migrating from a federated architecture to an integrated modular architecture based on a multi-core to reduce the number of systems, weight, power consumption, and platform redundancy. The volume of data which must bo provided to the pilot through the display device has increased, because an integrated single device performs multiple functions. For this reason, the volume of data processed by the graphic processor within a fixed operation period has increased. In this paper, we provide a multi-core-based rendering engine in to perform more graphics processing within a fixed operation period. We assume the proposed method uses a multi-core-based partitioning operating system using the AMP (Asymmetric Multi-Processing) architecture.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.264-264
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• 2019

개수로 흐름 해석을 위해 수치모형을 적용할 때 반드시 거쳐야 하는 과정이 격자망을 구성하는 일이다. 불규칙한 형상의 자연수로를 모의할 때 격자망 생성은 쉬운 일이 아니며, 따라서 가시적으로 격자망 생성을 돕고, 격자망의 수정도 용이한 도구가 요구된다. 따라서 본 연구에서는 수심적분된 흐름방정식을 지배방정식으로 하여 개수로 흐름 해석을 용이하게 하고자 그래픽 사용자 인터페이스(GUI)를 개발하였으며, 이를 소개하고자 한다. 격자망은 기본적으로 사각형과 삼각형 요소로 구성될 수 있으며, 유한차분모형 등에서는 정형사각형 격자망을, 유한요소모형에서는 비정형 사각형 및 삼각형 격자망 또는 혼합망을 생성시킬 수 있다. 이산점(scatter points)이나 절점(node points)을 생성하거나 기존의 자료를 불러들여 삼각망 또는 사각망을 형성시킬 수 있으며, 연속선(polylines)을 작성하여 형성된 폐다각형(polygones)을 이용하여 정규 또는 비정규의 삼각망 또는 사각망을 형성시킬 수 있다. 또한 두 점사이를 선형 또는 반원 형태로 편향 정도(biased value)를 설정하여 원하는 개수만큼 나눌 수 있도록 하여, 보다 효율적인 격자형성이 가능토록 하였다. 기존 상용 프로그램에서 작성된 격자를 불러들여 활용 가능하며, 백그라운드 이미지로 지형도나 위성사진을 띄어놓고 이미지 상에서 격자를 형성할 수도 있다. 기본적으로 마우스를 이용하여 화면의 이동, 확대 및 축소와 점, 선, 요소의 생성 및 선택이 가능하다. 본 프로그램은 Qt와 modern OpenGL을 바탕으로 제작되었으며, 마이크로소프트사의 windows 뿐만 아니라 Mac OS, Linux 버전의 설치 파일 작성이 가능하다.

• Archives of Pharmacal Research
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• v.24 no.6
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• pp.557-563
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• 2001

Oral tolerance is thought to play a role in preventing allergic responses and immune-mediated diseases. An improved mouse model of the oral tolerance to Japanese cedar pollen (JCP) as antigen was developed in order to detect induction of the tolerance, and the immunological characteristics of this model were also elucidated. Oral tolerance was induced by C3H/ HeN mice given an oral administration of 10 mg JCP 7 days before immunization with an i.p. injection of 0.1 mg JCP in complete Freunds adjuvant (CFA). The effects of oral JCP on systemic immunity were assessed by enzyme-linked immunosorbent assay (ELISA) of immunoglobulin (Ig) levels in serum collected on day 7 or 14 after immunization. Oral tolerance to JCP was adequately induced on day 7 after immunization and was more effective in C3H/HeN mice than in BALB/c mice. The tolerance was primarily concerned with the decreased serum levels of antigen-specific IgG. In these mice, oral administration of JCP also suppressed various immune responses to the antigen including delayed-type hypersensitivity (DTH), total Igl level and anti-JCP IgGl level. The suppression of these immune responses by the oral antigen was associated with a significant reduction in interleukin-4 (IL-4) production. These findings therefore indicate that this C3H/HeN mice model has potential use in detecting the induction of oral tolerance by JCP and suggest that this tolerance model may be effective in the treatment and prevention of allergic responses caused by the antigen.

• Korean Journal of Environmental Agriculture
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• v.40 no.2
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• pp.127-133
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• 2021

BACKGROUND: Dithiocarbamte fungicides have been used in crop cultivation for diseases protection and treatment. And cultivated agricultrual products were used as feedstuff, and residual pesticides are likely to be absorbed and transferred to livestock. But the maximum residue limits (MRLs) were not established for dithiocarbate fungicides in livestock products, and thus an analysis method was developed and validated for dithiocarbamate fungicides to establish MRLs. METHODS AND RESULTS: Samples were prepared using CS₂ trap method and detected with UV/VIS spectrophotometer. Calibration line (0.1 ~ 10 ㎍/mL) was linear with r² > 0.99. For validation, the recovery tests were carried out at three fortification levels (MLOQ, 10 MLOQ and 50 MLOQ) from livestock samples (egg, milk, beef, pork, and chicken). The results for mancozeb, propineb, and thiram ranged between 76.8 to 109.6%, 79.4 to 108.8%, and 80.2 to 107.8%, respectively and % RSD (relative standard deviation) values were below 9.5%. Furthermore, inter-laboratory analysis was performed to validate the method. CONCLUSION: All values were corresponded with the criteria ranges requested by both the CODEX (CAC/GL 40-1993, 2003) and MFDS guidelines (2016). This might be used as an official analytical method for determination of dithiocarbamate fungicides at established MRLs and monitoring.

• Atmosphere
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• v.29 no.2
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• pp.149-164
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• 2019

The purpose of this study is to introduce the improvement of current operational climate prediction system of KMA and to compare previous and improved that. Whereas the previous system is based on GloSea5GA3, the improved one is built on GloSea5GC2. GloSea5GC2 is a fully coupled global climate model with an atmosphere, ocean, sea-ice and land components through the coupler OASIS. This is comprised of component configurations Global Atmosphere 6.0 (GA6.0), Global Land 6.0 (GL6.0), Global Ocean 5.0 (GO5.0) and Global Sea Ice 6.0 (GSI6.0). The compositions have improved sea-ice parameters over the previous model. The model resolution is N216L85 (~60 km in mid-latitudes) in the atmosphere and ORCA0.25L75 ($0.25^{\circ}$ on a tri-polar grid) in the ocean. In this research, the predictability of each system is evaluated using by RMSE, Correlation and MSSS, and the variables are 500 hPa geopotential height (h500), 850 hPa temperature (t850) and Sea surface temperature (SST). A predictive performance shows that GloSea5GC2 is better than GloSea5GA3. For example, the RMSE of h500 of 1-month forecast is decreased from 23.89 gpm to 22.21 gpm in East Asia. For Nino3.4 area of SST, the improvements to GloSeaGC2 result in a decrease in RMSE, which become apparent over time. It can be concluded that GloSea5GC2 has a great performance for seasonal prediction.

• Journal of the Society of Naval Architects of Korea
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• v.56 no.4
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• pp.343-351
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• 2019

Green water impact may sometimes cause some structure damages on ship's bow deck. Prediction of proper design pressure against the green water impact is an essential task to prevent the possible damages on bow deck. This paper presents a computational method of the bow deck's design pressure against the green water impact. Large heave and pitch motions of ship are calculated by the time domain nonlinear strip method. Green water flow and pressure on bow deck are simulated by the predictor-corrector second kind upstream finite difference method. This green water simulation method is based on the shallow water wave equations expanded for moving bottom conditions. For various kind of ships such as container ship, VLCC, oil tanker and bulk carrier, the green water design pressures on bow deck are computed and discussed. Also, the obtained results of design pressure on bow deck are compared with those of the classification society rules and discussed.

• International Journal of Advanced Culture Technology
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• v.7 no.1
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• pp.243-247
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• 2019

The most commonly used 3D modeling file formats are OBJ (Wavefront file format specification) and STL (STereoLithography). Although they have a common point of view in 3D on the screen, detailed functions are different according to purpose of development. OBJ is the most commonly used 3D file format and STL is mainly used as 3D file format for 3D printing. However, in the field of Scientific Visualization, precise analysis is required. There is a difference in accuracy depending on the type of 3D file format. OBJ and STL are not suitable for delicate surface description because they form meshes in the form of triangular polygons. And if you increase the number of triangle polygons, it will be smoother, but the file size also increases exponentially and causes excessive CPU usage. In contrast, VTK provides a variety of polygon structures, including triangular polygons as well as rectangular polygons and cube polygons. Thus, delicate surface depiction is possible. Delicate surface rendering is possible and file size is not large. This paper describes the concept and structure of VTK. We also compared the load times and file sizes between VTK, STL, and OBJ in the Chrome browser. In addition, the difference in surface rendering ability between VTK, STL, and OBJ is intuitively viewed based on the screen in which each 3D file format is implemented under the same conditions. This study is expected to be helpful for efficient 3D file format for precise implementation of Web - based Scientific Visualization.

• Korean Journal of Environmental Agriculture
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• v.38 no.1
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• pp.1-9
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• 2019

BACKGROUND: Accurate and simple analytical method determining Fluxametamid residue was necessary in various food matrices. Additionally, fulfilment of the international guideline of Codex (Codex Alimentarius Commission CAC/GL 40) was required for the analytical method. In this study, we developed Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) method to determine the Fluxametamid residue in foods. METHODS AND RESULTS: Fluxametamid was extracted with acetonitrile, partitioned and concentrated with dichloromethane. To remove the interferences, silica SPE cartridge was used before LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) analysis with $C_{18}$ column. Five agricultural commodities (mandarin, potato, soybean, hulled rice, and red pepper) were used as a group representative to verify the method. The liner matrix-matched calibration curves were confirmed with coefficient of determination ($r^2$) greater than 0.99 at calibration range of 0.001-0.25 mg/kg. The limits of detection and quantification were 0.001 and 0.005 mg/kg, respectively. Mean average accuracies were shown to be 82.24-115.27%. The precision was also shown to be less than 10% for all five samples. CONCLUSION: The method investigated in this study was suitable to the Codex guideline for the residue analysis. Thus, this method can be useful for determining the residue in various food matrices as routine analysis.

• Journal of the Korea Convergence Society
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• v.12 no.2
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• pp.193-200
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• 2021

As the degree of environmental pollution caused by the use of fossil fuels intensifies, many countries continue to invest in the development of alternative energy. PEMFC, one of the alternative energies, consists of four main components: bipolor plate, electrolyte, gas diffusion layer, and electrode. Among them, bipolor plate, the gas diffusion layer, and electrode are generally manufactured using carbon materials such as carbon black and carbon fiber. These carbon materials are expensive in manufacturing process or have disadvantages such as corrosion, and research is being conducted in many fields to improve this. This paper collects several research results conducted to improve the shortcomings of these three components and examines the trends of PEMFC by grasping what problems have been and how they have improved.

• Biomolecules & Therapeutics
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• v.29 no.2
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• pp.184-194
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• 2021

Histone acetylation is a well-characterized epigenetic modification controlled by histone acetyltransferases (HATs) and histone deacetylases (HDACs). Imbalanced histone acetylation has been observed in many primary cancers. Therefore, efforts have been made to find drugs or small molecules such as HDAC inhibitors that can revert acetylation levels to normal in cancer cells. We observed dose-dependent reduction in the endogenous and exogenous protein expression levels of KAT8 (also known as human MOF), a member of the MYST family of HATs, and its corresponding histone acetylation at H4K5, H4K8, and H4K16 in chemotherapy drug gemcitabine (GEM)-exposed T24 bladder cancer (BLCA) cells. Interestingly, the reduction in MOF and histone H4 acetylation was inversely proportional to GEM-induced γH2AX, an indicator of chemotherapy drug effectiveness. Furthermore, pGL4-MOF-Luc reporter activities were significantly inhibited by GEM, thereby suggesting that GEM utilizes an MOF-mediated anti-BLCA mechanism of action. In the CCK-8, wound healing assays and Transwell® experiments, the additive effects on cell proliferation and migration were observed in the presence of exogenous MOF and GEM. In addition, the promoted cell sensitivity to GEM by exogenous MOF in BLCA cells was confirmed using an Annexin V-FITC/PI assay. Taken together, our results provide the theoretical basis for elucidating the anti-BLCA mechanism of GEM.