• Journal of Food Hygiene and Safety
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• v.35 no.3
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• pp.279-283
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• 2020

In this study we evaluated the antimicrobial effects of EcoCal^® (calcium oxide) and GF Bactostop^® (organic acids mix) in sausages during storage at 10℃. The sausages were formulated with 0.1% EcoCal^® (0.1ECO), 0.1% EcoCal^®+0.5% GF Bactostop^® (0.1ECO+0.5GF), 0.2% EcoCal^® (0.2ECO), and 0.2% EcoCal^®+0.5% GF Bactostop^® (0.2ECO+0.5GF). Total aerobic and lactic acid bacteria in the sausages were enumerated on tryptic soy agar and Lactobacilli MRS agar, respectively, during storage at 10℃ for 10 weeks. The 0.1ECO+0.5GF showed the most effective antimicrobial effects on the sausages, and 0.1ECO showed the second most effective antimicrobial effect. Total aerobic bacterial cell counts gradually increased in the control, 0.2ECO, and 0.2ECO+0.5GF groups, but cell growth was generally inhibited in 0.1ECO by approximately day 42 (P<0.05) and 0.1ECO+0.5GF by approximately day 49 (P<0.05). Lactic acid bacterial cell counts gradually increased in the control, 0.2ECO, and 0.2ECO+0.5GF groups, but the lactic acid bacteria growth was inhibited in 0.1ECO by approximately day 49 (P<0.05) and in 0.1ECO+0.5GF by approximately day 64. These results suggest that using 0.1% EcoCal^®+0.5% GF Bactostop^® in sausage formulation is useful for inhibiting lactic acid bacteria growth, thereby extending the shelf-life of the sausage product.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.2A
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• pp.80-85
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• 2003

This paper proposes Galois Field Arithmetic Unit(GFAU) whose structure does addition, multiplication and division in GF(2m). GFAU can execute maximum two additions, or two multiplications, or one addition and one multiplication. The base architecture of this GFAU is a divider based on modified Euclid's algorithm. The divider was modified to enable multiplication and addition, and the modified divider with the control logic became GFAU. The GFAU for GF(2193) was implemented with Verilog HDL with top-down methodology, and it was improved and verified by a cycle-based simulator written in C-language. The verified model was synthesized with Samsung 0.35um, 3.3V CMOS standard cell library, and it operates at 104.7MHz in the worst case of 3.0V, 85$^{\circ}C$, and it has about 25,889 gates.

• Food Engineering Progress
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• v.21 no.1
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• pp.64-71
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• 2017

This study investigated the effects of the mixing ratio of tofu paste and normal corn starch on the characteristics of gluten-free (GF) muffins. Soft wheat flour for wheat flour-based muffins (control) was replaced with the mixture of tofu paste and normal corn starch (NCS). The mixing ratios of tofu paste and NCS were 1:6.4 (S100), 1:5.1 (S80), 1:3.8 (S60), 1:2.6 (S40), 1:1.3 (S20), and 1:0 (S00), based on their total solid contents. GF muffins of S40-S100 developed the porous, sponge-like structure without crumb collapse. The weight and baking loss did not significantly differ in the control and GF muffins. By decreasing NCS in GF muffin batters, the moisture content, firmness, and crumb redness/yellowness of GF muffins increased, while their volume, specific volume, and crumb lightness decreased. Nevertheless, these characteristics (except for firmness) of S100 were much closer to those of the control. In the preference test, however, S60 (possessing lower attributes than S100 and S80) was most favored among GF muffins, and was very similar in all evaluations (except for appearance) to the control. Overall, the mixture of tofu paste and NCS would be a potential material to replace soft wheat flour in muffins.

• Archives of Pharmacal Research
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• v.27 no.2
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• pp.217-224
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• 2004

Previously, we reported that water-extracted Acanthopanax senticasus exhibited anti-meta-static activity by stimulating the immune system. In this study, we fractionated glycoproteins (EN-SP) from the soluble protein layer (GF-AS) of A. senticasus and determined their basic chemical properties. We also investigated the anti-tumor and immunostimulating activities of the fractionated glycoprotein, EN-SP. We found that intravenous (i.v.) administration of GF-AS dramatically inhibited metastasis of colon26-M3.1 carcinoma cells to the lung in a dose-dependent manner. In vitro analysis showed GF-AS to enhance the proliferation of splenocytes. GF-AS also stimulated peritoneal macrophage, which was followed by the production of various cytokines such as IL-1$\beta$, TNF-$\alpha$, IL-12 and IFN-${\gamma}$. Furthermore, the production of these cytokines was partially blocked when peritoneal macrophage was cultured with the polyclonal antibodies against GF-AS. The depletion of NK cells by rabbit anti-asialo GM1 serum partly abolished the inhibitory effect of GF-AS on lung metastasis of colon26-M3.1 cells. Using gel filtration, EN-SP, an active glycoprotein fraction, is isolated from GF-AS. While both GF-AS and EN-SP stimulated the proliferatation of splenocytes of normal mice, EN-SP showed higher anti-metastatic activity and more potently stimulated the proliferation of splenocytes compared to GF-AS. These results suggest the use of EN-SP, the fractionated glycoprotein from A. senticasus, can be used as a therapeutical reagent to prevent or inhibit tumor metastasis.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.1
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• pp.1-16
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• 2014

Objectives: The purpose of this study was to investigate the effects of Gardeniae Fructus Water Extract (GF) on the production of inflammatory mediators in RAW 264.7 cell treated with lipopolysaccharide (LPS). Methods: Gradeniae Fructus was extracted with distilled water (2,000 ml) for 2 hours. In order to evaluate cytotoxicity of GF, 3 - (4,5-dimethylthiazol-2-yl) - 2,5 - diphenyltetrazolium bromide (MTT) assay was performed. To investigate antiinflammatory effects, the concentration of nitric oxide (NO) was measured with No assay, calcium (Ca) was measured with Fluo-4 Ca assay, and cytokine was measured by Bio-Plex cytokine assay in RAW 264.7 cell. And when p-value is below 0.05, it is judged to have the significant difference statistically. Results: 1. GF did not show any cytotoxicity. 2. GF suppressed the production of NO and Ca at the concentration of 25, 50, 100 and $200{\mu}g/ml$. 3. GF suppressed the production of interleukin (IL)-$1{\beta}$, IL-10, IL-12p40, macrophage-colony stimulating factor (M-CSF), macrophage inflammatory protein (MIP)-$1{\beta}$ and keratinocyte chemoattractant(KC) at the concentration of 25, 50, 100 and $200{\mu}g/ml$. 4. GF suppressed the production of vascular endothelial growth factor (VEGF), granulocyte-colony stimulating factor (G-CSF) and monocyte cheomattractant protein (MCP)-1 at the concentration of 25, 50 and $100{\mu}g/ml$. 5. GF suppressed the production of granulocyte macrophage-colony stimulating factor (GM-CSF) and regulated on activation, normal T cell expressed and secreted (RANTES) at the concentration of 25 and $50{\mu}g/ml$. 6. GF suppressed the production of MIP-2 at the concentration of 50 and $100{\mu}g/ml$, and tumor necrosis factor (TNF)-${\alpha}$ at the concentration of 50 and $200{\mu}g/ml$. Conclusions: These results suggest that GF has anti-inflammatory effect and immuno-modulating activity.

• Journal of Ginseng Research
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• v.47 no.3
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• pp.420-428
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• 2023

Background: Ginsenoside F2 (GF2), a minor component of Panax ginseng, has been reported to possess a wide variety of pharmacological activities. However, its effects on glucose metabolism have not yet been reported. Here, we investigated the underlying signaling pathways involved in its effects on hepatic glucose. Methods: HepG2 cells were used to establish insulin-resistant (IR) model and treated with GF2. Cell viability and glucose uptake-related genes were also examined by real-time PCR and immunoblots. Results: Cell viability assays showed that GF2 up to 50 μM did not affect normal and IR-HepG2 cell viability. GF2 reduced oxidative stress by inhibiting phosphorylation of the mitogen-activated protein kinases (MAPK) signaling components such as c-Jun N-terminal kinase (JNK), extracellular signal-regulated kinase 1/2 (ERK1/2), and p38 MAPK, and reducing the nuclear translocation of NF-κB. Furthermore, GF2 activated PI3K/AKT signaling, upregulated the levels of glucose transporter 2 (GLUT-2) and GLUT-4 in IR-HepG2 cells, and promoted glucose absorption. At the same time, GF2 reduced phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression as well as inhibiting gluconeogenesis. Conclusion: Overall, GF2 improved glucose metabolism disorders by reducing cellular oxidative stress in IR-HepG2 cells via MAPK signaling, participating in the PI3K/AKT/GSK-3β signaling pathway, promoting glycogen synthesis, and inhibiting gluconeogenesis.

• Journal of the Korea Concrete Institute
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• v.28 no.3
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• pp.289-298
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• 2016

An experimental research was performed using fibers for the purpose of retrofitting existing reinforced concrete circular columns. Glass fiber (GF) and polyethylene terephthalate (PET) were used as well as combined GF+PET (HF). PET has high tensile strength (over 600 MPa) and high ductility (about 15%), but has very low elastic modulus (about 1/6 of GF). A total of four columns was tested against laterally applied reverse cyclic load: control column, GF-, PET-, and HF-strengthened columns. All columns retrofitted using fibers demonstrated improved moment capacity and ductility. Moment capacity of GF-, PET-, and HF-strengthened columns was 120%, 107%, and 120% of the control column, respectively. Drift ratio of all retrofitted columns also increased by 63 ~ 83% over the control column. The final failure mode of the control column was main bar buckling. The final failure mode of the GF- and HF-strengthened columns was GF rupture while that of the PET-strengthened column was main bar rupture in tension. No damage was observed for PET at the ultimate stage due to excellent strain capacity intrinsic to PET. Current test results indicate that PET can be effectively used for seismic retrofit of RC columns. It is noted that the durability characteristics of PET needs to be investigated in the future.

• Applied Biological Chemistry
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• v.36 no.4
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• pp.304-309
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• 1993

The composition of soluble neutral carbohydrates in jerusalem artichoke tubers was measured and compared according to harvest dates and storage temperatures using HPLC. The breakdown of inulin $({\ge}GF8)$ into sucrose and fructo-oligosaccharides (GF2-GF7) was highest on November just after cold-shock. The composition of sucrose and fructo-oligosaccharides on March was much higher than that on September of previous year. Inulin $({\ge}GF8)$ proportion decreased from 66.4% to 33.1% but the proportion of fructo-oligosaccharides (GF2-GF7) and sucrose increased from 25% to 61% and from 3.4% to 13.6%, respectively. The storage at a low temperature $(4^{\circ}C)$ for 34 days increased the composition as well. However, the amount of fructo-oligosaccharides was decreased when the tubers harvested in March were stored at high temperature $(25^{\circ}C{\sim}40^{\circ}C)$. For the maximam yield of fructo-oligosaccharides in jerusalem artichoke, it is concluded that the tubers be harvested in March and/or stored at the low temperature.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.34 no.5
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• pp.841-853
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• 2024

This paper proposes an optimization method for the GF(2)[x] multiplication operation in HQC on AVX2. HQC is a candidate in NIST PQC standardization round 4 and is a binary code-based key exchange algorithm. The multiplication operation is one of the most time-complex operations in HQC, accounting for about 30% of the total clock cycles in the AVX2 environment. For the optimization, we used Karatsuba and Toom-Cook algorithms. Both algorithms are based on divide-and-conquer methods, which require multiplications of smaller order within them. We propose a method to optimize polynomial multiplication in HQC by finding the most efficient combination of Karatsuba and Toom-Cook algorithms, and compare the performance of the proposed method based on the implementation submitted to the PQC standardization. The results of the comparison demonstrate a performance improvement of 4.5%, 2.5%, and 30.3% over the GF(2)[x] multiplications of original hqc-128, -192, and -256. When applied to key generation, encapsulation, and decapsulation, the performance improvement over the original HQC is 2.2%, 2.4%, and 2.3% for hqc-128, 1.6%, 4.2%, and 2.6% for hqc-192, and 13.3%, 14.7%, and 13.3% for hqc-256, respectively.

• Journal of IKEEE
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• v.3 no.2 s.5
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• pp.285-294
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• 1999

This paper presents a method for the generation of GRM coefncients over GF(3) by using a comparison of polarity. In general production method to GRM coefficients over GF(3) is searching for pn different polarity of an n-variable and from these optimal function according to the maximum number of zero coefficients is selected. This paper presents a method for the generation of GRM coefficients by means of compare to the number of zero coefficients without constructing the whole polarity GRM coefficients.