• Journal of Fisheries and Marine Sciences Education
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• v.25 no.5
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• pp.1079-1087
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• 2013

The pharmacokinetics of florfenicol (FF) after oral administration was studied in the cultured olive flounder, Paralichthys olivaceus, using high performance liquid chromatography (HPLC). After single administration of FF (20 mg/kg body weight) by oral route in olive flounder ($700{\pm}50$ g, $23{\pm}1.5^{\circ}C$), the concentration in the serum was determined at 1, 5, 10, 15, 24, 30, 50 and 168 h post-dose. The kinetic profile of absorption, distribution and elimination of FF in serum were analyzed fitting to a two-compartment model by WinNonlin program. The area under the concentration-time curve (AUC), maximum concentration ($C_{max}$), time for maximum concentration ($T_{max}$) and elimination time were 22.51 ${\mu}g{\cdot}h/mL$, 0.84 ${\mu}g/mL$, 8.62 h and 447 h, respectively. The results of this study related to dosage and withdrawal times could be used for prescription of FF in field for the treatment of bacterial diseases in olive flounder.

• Journal of Microbiology and Biotechnology
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• v.26 no.6
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• pp.1103-1108
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• 2016

Yam anthracnose caused by Colletotrichum gloeosporioides (C.g) is the most devastating disease of yam (Dioscorea sp.). In the present study, we evaluated the culture filtrate extract (CFE) of azalomycin-producing Streptomyces malaysiensis strain MJM1968 for the control of yam anthracnose. MJM1968 showed strong antagonistic activity against C.g in vitro. Furthermore, the MJM1968 CFE was tested for inhibition of spore germination in C.g, where it completely inhibited spore germination at a concentration of 50 μg/ml. To assess the in planta efficacy of the CFE and spores of MJM1968 against C.g, a detached leaf bioassay was conducted, which showed both the treatments suppressed anthracnose development on detached yam leaves. Furthermore, a greenhouse study was conducted to evaluate the CFE from MJM1968 as a fungicide for the control of yam anthracnose. The CFE non-treated plants showed a disease severity of >92% after 90 days of artificial inoculation with C.g, whereas the disease severity of CFE-treated and benomyl-treated yam plants was reduced to 26% and 15%, respectively, after 90 days. Analysis of the yam tubers from the CFE-treated and non-treated groups showed that tubers from the CFE-treated plants were larger than that of non-treated plants, which produced abnormal smaller tubers typical of anthracnose. This study demonstrated the utility of the CFE from S. malaysiensis strain MJM1968 as a biofungicide for the control of yam anthracnose.

• 한국전산유체공학회:학술대회논문집
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• 2009.04a
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• pp.125-129
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• 2009

In this paper automatic 3D wing shape modeling program is introduced. The program is developed in Visual Basic based on Net Framework 3.5 environment by using CATIA COM Library, and it is used together with CATIA system to model 3D wings with or without flaps. With this program users can easily construct wing models by specifying geometry parameters which are usually design variables with the aid of easy-to-use GUI environment, and specifying sectional airfoil data is done either by using analytic shape functions such as NACA series airfoils or by providing input files with point data describing the airfoil shape. When all the input parameters are provided, users can either work further with the model in the CATIA system which would be automatically started by the program or save the resultant model in the format of users choice. Unstructured grid generation program is also briefly described which can make grid generation task for a 3D wing easy and efficient one when used together with the wing modeling program by choosing STL format as the model's output format.

• Journal of Korean Academy of Nursing
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• v.37 no.4
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• pp.467-477
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• 2007

Purpose: The purpose of this study was to analyze the effects of a pruritus intervention program on pruritus and sleep satisfaction in patients undergoing hemodialysis. Method: This study was designed for a nonequivalent control group repeated measures quasi-experimental study. Hemodialysis patients were recruited from a kidney center at a university hospital located in G city, Korea. The subjects consisted of 43 patients 21 for the experimental group and 22 for the control group. The 2-week pruritus intervention program was given to the experimental group only. An analytical survey was done before and after the pruritus intervention program. Result: There was a significant decrease in pruritus and increase in sleep satisfaction in the experimental group compared to the control group. There was significant improvement in clinical symptoms and sleep satisfaction after completing the pruritus intervention program in the experimental group. Conclusion: Pruritus intervention program in hemodialysis patients decreased pruritus severity and increased sleep satisfaction, which can be used as an efficient nursing intervention for hemodialysis patients.

• Journal of the Korea Computer Industry Society
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• v.4 no.10
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• pp.685-694
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• 2003

This paper has been studied on the prevent of "program reproduce" and "partial modification" in computer programming. The system is made for the improvement for the prevention of prevailing "program reproduce" and "program partial modification", this research will be helpful to the student who is interested in depth study programmer. The research using AST will do the work such as finding errors of program and will evaluate how much each program is similar to each other. The research using AST will show you, on the screen, by using pictures how much each programs are assimilated. This system supports all of technique available in various forms on the areas of cyber education at present, cyber university, lecture on demand, electronic library, etc. It is expected that the new system can be contributed to opening the new chapter of computer education.g the new chapter of computer education.

• Korean Journal of Adult Nursing
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• v.27 no.2
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• pp.135-145
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• 2015

Purpose: The purpose of this study was to evaluate the effects of a colonoscopy simulation program on knowledge and clinical performance among nursing students. Methods: The program consisted of a scenario with three objectives: health assessment, nursing before/after colonoscopy and emergency care for bleeding following the colonoscopy. A nonequivalent control group pretest-posttest design was used. The sample was 149 nursing students recruited from H University in G city from August, 2013 to December, 2014. The treatment group (n=71) received the simulation and the comparison group (n=78) received the usual lecture program. Data were analyzed using descriptive statistics, ${\chi}^2$ test, t-test and repeated measure ANOVA using the SPSS/WIN 20.0 program. Result: Participants in the treatment group had significantly increased reported scores on both knowledge and clinical performance. Conclusion: Results indicate that the simulated program is a useful strategy for improving knowledge and clinical performance among nursing students. The development of simulation practice programs in a variety of fields are needed in order to promote the practical competence of nursing students.

• Journal of Korean Public Health Nursing
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• v.21 no.1
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• pp.85-94
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• 2007

Purpose: This study examined the effects of Interpersonal Relationship Improvement Program Applied MMTIC on self-esteem and interpersonal relationships. Method: The survey was carried out from September to November, 2005. The subjects were 32 middle school students in G City. To test the effects of the Interpersonal Relationship Improvement Program Applied MMTIC, the subjects were divided into two groups, 16 in the experimental group and 16 in the control group. The research design used in this study was a nonequivalent control group pre-test and post-test design in quasi-experimental research. The research tools included MMTIC(Murphy-Meisgeier Type Indicator for Children), self-esteem scale, and interpersonal relationship scale. The collected data was analyzed using Chi-square test, paired t-test, and t-test on the SPSS/WIN 10.0 program. Result: Significant differences were found in the self-esteem scores and interpersonal relationship between the middle school students who had participated in the Interpersonal Relationship Improvement Program Applied MMTIC and those who did not. Conclusion: Therefore, it appears that the Interpersonal Relationship Improvement Program Applied MMTIC is a useful nursing intervention for improving the self-esteem and interpersonal relationships of middle school students.

• Women's Health Nursing
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• v.14 no.1
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• pp.36-43
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• 2008

Purpose: This study was conducted to develop a postpartum care program and to evaluate the effects of the program on postpartum activity and postpartum discomfort in primiparous women. Methods: For this control group quasi-experimental study, primiparous women who had a normal delivery at OBGYN clinics in G-city and then went home with assistance from their mothers participated from April 10 to August 2, 2006. The participants were assigned to an intervention group of 25 mothers or a control group of 23 mothers. Data analysis was performed by using SPSS/win10.0 PC+. $X^2$-test and t-test, and repeated measure ANOVA. Results: The results showed that the degree of postpartum activity(F=4.66, p=.036) and the degree of postpartum discomfort(F=7.98, p=.007) were supported statistically with significant differences between the two groups. Conclusions: Therefore, this program needs to be applied as a new nursing intervention because this postpartum care program was proven useful as effective postpartum care.

• Korean Journal of Adult Nursing
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• v.27 no.5
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• pp.572-582
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• 2015

Purpose: This study was conducted to provide an effective nursing intervention using an individualized educational program composed with knowledge, compliance, and physiologic parameters for long-term hemodialysis patients. Methods: A quasi-experimental study using a non-equivalent control group and pre- and post-test design was conducted with 40 hemodialysis patients at G university hospital in the J city from June to August, 2015. A data was analyzed using frequency, percentage, ${\chi}^2$ test, Shapiro-Wilk test, independent-samples t-test and repeated measures ANOVA using SPSS 21.0 program. Results: knowledge about hemodialysis and patient role behaviors were not significantly different between the two measures. In the biological index, there was significant difference between the groups by points in time and group in blood potassium, albumin, and Kt/v. However, there was no difference in gaining weight between hemodialysis, hemoglobin, and blood phosphorus. Conclusion: The individual training program in this study had an effect on changing some physiological indicators of long-term hemodialysis patients. Future research is warranted for developing various kinds of education program incorporating the findings of the study for the given population.

• Journal of Korean Academy of Nursing
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• v.46 no.2
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• pp.183-193
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• 2016

Purpose: The purpose of this study was to identify the effects of the program to promote drinking knowledge, attitudes, and coping behavior in preschool children. Methods: A quasi-experimental with non-equivalent control group pretest-posttest design was conducted. The participants were 123 five year old children from G city. They were assigned to the experimental group (n=77) or the control group (n=46). A pretest and posttest were conducted to measure main variables. For the experimental group, the drinking prevention program was given for 6 weeks. Data were analyzed using ${\chi}^2$-test, t-test, and ANCOVA. Results: After the intervention, preschool children in the experimental group reported significant differences in drinking knowledge (F=9.25, p =.003), drinking attitudes (F=19.57, p<.001), and coping behavior (F=16.38, p<.001) compared to preschool children in the control group. Conclusion: The results of this study indicate that a drinking prevention program for preschool children is effective in increasing drinking knowledge, attitudes, and coping behavior. This drinking prevention program is recommended as an effective intervention for preschool age children to postpone an early introduction to drinking.