• 제목/요약/키워드: G-T model

검색결과 996건 처리시간 0.029초

Meta-analysis of Associations between the MDM2-T309G Polymorphism and Prostate Cancer Risk

  • Chen, Tao;Yi, Shang-Hui;Liu, Xiao-Yu;Liu, Zhi-Gang
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권9호
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    • pp.4327-4330
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    • 2012
  • The mouse double minute 2 (MDM2) gene plays a key role in the p53 pathway, and the SNP 309T/G single-nucleotide polymorphism in the promoter region of MDM2 has been shown to be associated with increased risk of cancer. However, no consistent results were found concerning the relationships between the polymorphism and prostate cancer risk. This meta-analysis, covering 4 independent case-control studies, was conducted to better understand the association between MDM2-SNP T309G and prostate cancer risk focusing on overall and subgroup aspects. The analysis revealed, no matter what kind of genetic model was used, no significant association between MDM2-SNP T309G and prostate cancer risk in overall analysis (GT/TT: OR = 0.84, 95%CI = 0.60-1.19; GG/TT: OR = 0.69, 95%CI = 0.43-1.11; dominant model: OR = 0.81, 95%CI= 0.58-1.13; recessive model: OR = 1.23, 95%CI = 0.95-1.59). In subgroup analysis, the polymorphism seemed more likely to be a protective factor in Europeans (GG/TT: OR = 0.52, 95%CI = 0.31-0.87; recessive model: OR = 0.58, 95%CI = 0.36-0.95) than in Asian populations, and a protective effect of the polymorphism was also seen in hospital-based studies in all models (GT/TT: OR = 0.74, 95%CI = 0.57-0.97; GG/TT: OR = 0.55, 95%CI = 0.38-0.79; dominant model: OR = 0.69, 95%CI = 0.54-0.89; recessive model: OR = 0.70, 95%CI = 0.51-0.97). However, more primary studies with a larger number of samples are required to confirm our findings.

N-정책과 T-정책이 적용되는 M/G/1 시스템의 분석 (An Analysis of M/G/1 System with N and T-Policy)

  • 허선;이훈규;김종수
    • 대한산업공학회지
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    • 제26권2호
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    • pp.81-87
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    • 2000
  • As for M/G/1 queueing system, we use various control policies, with which we can optimize the system. Up to now the most widely adopted policies are N-Policy, T-Policy, D-Policy, and so on. The existing researches are largely concerned to find an optimal operation condition or to optimize the system under single policy in M/G/1 system. There are, however, few literatures dealing with multiple control policies at once to enhance the flexibility of the model. In this study, we consider M/G/1 system adopting N-Policy and T-Policy simultaneously. If one of two conditions is satisfied, then, the server starts the service. We call this Min(N,T)-Policy. We find the probability distribution of the number of customers and mean waiting time in steady state and derive a cost function. Next, we seek the $N^*$, optimal threshold under various N values. Finally, we reveal the characteristics of cost function.

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A Spatial Structural Query Language-G/SQL

  • Fang, Yu;Chu, Fang;Xinming, Tang
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2002년도 Proceedings of International Symposium on Remote Sensing
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    • pp.860-879
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    • 2002
  • Traditionally, Geographical Information Systems can only process spatial data in a procedure-oriented way, and the data can't be treated integrally. This method limits the development of spatial data applications. A new and promising method to solve this problem is the spatial structural query language, which extends SQL and provides integrated accessing to spatial data. In this paper, the theory of spatial structural query language is discussed, and a new geographical data model based on the concepts and data model in OGIS is introduced. According to this model, we implemented a spatial structural query language G/SQL. Through the studies of the 9-Intersection Model, G/SQL provides a set of topological relational predicates and spatial functions for GIS application development. We have successfully developed a Web-based GIS system-WebGIS-using G/SQL. Experiences show that the spatial operators G/SQL offered are complete and easy-to-use. The BNF representation of G/SQL syntax is included in this paper.

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갯벌과 황토에 의한 중금속 (Cu, Cd, Pb)의 흡착 kinetics (Adsorption Kinetics of metals (Cu, Cd, Pb) in Tidal Flat Sediments and Yellow Loesses)

  • 유선재;김종구;김종배
    • 한국수산과학회지
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    • 제33권3호
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    • pp.250-256
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    • 2000
  • 조성이 다른 3곳 갯벌과 적조구제를 위해 사용되는 2곳의 황토를 이용해 금속 (Cu, Cd 및 Pb)의 흡착 kinetic을 밝히고, nonlinear regression model을 이용하여 구한 흡착속도와 갯벌의 조성과의 관계를 평가해 보았다. 중금속흡착에 영향을 주는 갯벌이나 황토의 조성 중에서 강열 감량 (I.L.), 산화철${\cdot}$망간${\cdot}$알루미늄의 함량은 황토가 갯벌보다 $1.5{\~}6$배 높았다. 하지만 니질의 함량은 어은리 갯벌이 다른 시료보다 $4{\~}50$배 많았다. 중금속흡착은 초기 30분 동안에 매우 빠르게 일어났다. 이때 흡착량은 Cu, Cd과 Pb이 각각 $4.1{\~}14.7\;{\mu}g/g,\;42.8{\~}16.7\;{\mu}g/g$ 그리고 $43.3{\~}101.7 {\mu}g/g$으로 3시간 실험 후 총 누적흡착량의 $8{\~}70{\%},\;18{\~}31{\%}$ 그리고 $19{\~}52{\%}$이었다. 흡착실험시 초기 금속농도를 동일 (약$ 0.5{\times}10^(-5)M$)하게 하여 운전한 결과 흡착량은 Pb>Cu>Cd 순으로 많았다. 중금속의 흡착 kinetic은 one-site kinetic model로 표현할 수 있었다. 특히 구리의 경우 non-linear model로 계산된 흡착속도 (Ka)와 3개 갯벌의 I.L., 산화알루미늄 및 니질 함량 사이에는 $R^2=-0.88{\~}-0.99$의 역 상관관계를 나타내었다.

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An Efficient Markov Chain Based Channel Model for 6G Enabled Massive Internet of Things

  • Yang, Wei;Jing, Xiaojun;Huang, Hai;Zhu, Chunsheng;Jiang, Qiaojie;Xie, Dongliang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제15권11호
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    • pp.4203-4223
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    • 2021
  • Accelerated by the Internet of Things (IoT), the need for further technical innovations and developments within wireless communications beyond the fifth generation (B5G) networks is up-and-coming in the past few years. High altitude platform station (HAPS) communication is expected to achieve such high levels that, with high data transfer rates and low latency, millions of devices and applications can work seamlessly. The HAPS has emerged as an indispensable component of next-generations of wireless networks, which will therefore play an important role in promoting massive IoT interconnectivity with 6G. The performance of communication and key technology mainly depend on the characteristic of channel, thus we propose an efficient Markov chain based channel model, then analyze the HAPS communication system's uplink capability and swing effect through experiments. According to the simulation results, the efficacy of the proposed scheme is proven to meet the requirements of ubiquitous connectivity in future IoT enabled by 6G.

Weak Convergence for Nonparametric Bayes Estimators Based on Beta Processes in the Random Censorship Model

  • Hong, Jee-Chang
    • Communications for Statistical Applications and Methods
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    • 제12권3호
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    • pp.545-556
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    • 2005
  • Hjort(1990) obtained the nonparametric Bayes estimator $\^{F}_{c,a}$ of $F_0$ with respect to beta processes in the random censorship model. Let $X_1,{\cdots},X_n$ be i.i.d. $F_0$ and let $C_1,{\cdot},\;C_n$ be i.i.d. G. Assume that $F_0$ and G are continuous. This paper shows that {$\^{F}_{c,a}$(u){\|}0 < u < T} converges weakly to a Gaussian process whenever T < $\infty$ and $\~{F}_0({\tau})\;<\;1$.

GIS를 이용한 서울 시범 지역에서의 부지고유 지진 응답의 정밀구역화 (Microzonation on Site-specific Seismic Response at a Model Area in Seoul Using GIS)

  • 선창국;천성호;장의룡;정충기
    • 한국방재학회 논문집
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    • 제7권5호
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    • pp.139-150
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    • 2007
  • 컴퓨터 기술이 급속히 발전됨에 따라, 최근에는 많은 분야에서 지리정보시스템(GIS)이 활용되고 있다. 이 연구에서는 서울 내의 한 시범 지역을 대상으로 지하 지반 조건에 따라 영향을 받는 부지 효과에 관련된 지진피해 가능성을 GIS 기법을 이용하여 평가하였다. 시범 지역에서의 지역적 부지고유 지진 응답의 평가를 위하여 서울 대도시 지역에 대한 기존 시추 조사 자료의 분포를 파악하였다. GIS 토대의 지반 정보 시스템(GTIS)을 구축하여 시범 지역 전체에 대한 공간 지층 정보를 예측하였다 서울 시법 지역의 부지고유 지진응답 예측을 위한 부지 주기$(T_G)$의 정밀구역화를 GTIS 내에서 수행하였다. 공간 분포 정밀구역화 지도로부터 시범 지역 내 2 층에서 4 층 건물들의 지진 취약성을 확인하였다. 또한, GTIS 내에서 $T_G$ 분포를 토대로 설계 지반 운동 결정을 위한 지반 분류 지도를 작성하였으며, 그로부터 대상 시범 지역 부지의 거의 대부분이 현행 지반 분류 C 와 D로 분류됨을 확인하였다. 이와 같은 서울 시범 지역에 대한 지진 정밀구역화 적용 구조 체계는 특별히 기존 시추 자료를 활용하여 대도시 서울 지역 전체에 대해 적용 가능할 것으로 판단된다.

Cohesive Zone Model을 이용한 접착제 물성평가 : 모드 I (Evaluation of Adhesive Properties Using Cohesive Zone Model : Mode I)

  • 이찬주;이상곤;고대철;김병민
    • 대한기계학회논문집A
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    • 제33권5호
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    • pp.474-481
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    • 2009
  • Fracture models and criteria of adhesive with two parameters, namely $G_C$ and ${\sigma}_{max}$, have been developed to describe the fracture process of adhesive joints. Cohesive zone model(CZM) is a representative two parameter failure criteria approach. In CZM, ${\sigma}_{max}$ is a critical, limiting maximum value of the stress in the damage zone ahead of the crack and is assumed to have some physical significance in adhesive failure. Based on CZM and finite element analysis method, the relationship between fracture load and adhesive properties, as $G_{IC)$ and $({\sigma}_{max})_I$, was investigated in adhesively bonded joint tensile test and T-peel test. The two parameters in tensile mode loading were evaluated by using the relationship. The value of $G_{\IC}$ evaluated by proposed method showed close agreement with analytical solution for tapered double cantilever beam(TDCB) test which proposed in an ASTM standard.

A BERRY-ESSEEN TYPE BOUND OF REGRESSION ESTIMATOR BASED ON LINEAR PROCESS ERRORS

  • Liang, Han-Ying;Li, Yu-Yu
    • 대한수학회지
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    • 제45권6호
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    • pp.1753-1767
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    • 2008
  • Consider the nonparametric regression model $Y_{ni}\;=\;g(x_{ni})+{\epsilon}_{ni}$ ($1\;{\leq}\;i\;{\leq}\;n$), where g($\cdot$) is an unknown regression function, $x_{ni}$ are known fixed design points, and the correlated errors {${\epsilon}_{ni}$, $1\;{\leq}\;i\;{\leq}\;n$} have the same distribution as {$V_i$, $1\;{\leq}\;i\;{\leq}\;n$}, here $V_t\;=\;{\sum}^{\infty}_{j=-{\infty}}\;{\psi}_je_{t-j}$ with ${\sum}^{\infty}_{j=-{\infty}}\;|{\psi}_j|$ < $\infty$ and {$e_t$} are negatively associated random variables. Under appropriate conditions, we derive a Berry-Esseen type bound for the estimator of g($\cdot$). As corollary, by choice of the weights, the Berry-Esseen type bound can attain O($n^{-1/4}({\log}\;n)^{3/4}$).

A simple creep constitutive model for soft clays based on volumetric strain characteristics

  • Chen, G.;Zhu, J.G.;Chen, Z.;Guo, W.L.
    • Geomechanics and Engineering
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    • 제29권6호
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    • pp.615-626
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    • 2022
  • The soft clays are widely distributed, and one of the prominent engineering problems is the creep behavior. In order to predict the creep deformation of soft clays in an easier and more acceptable way, a simple creep constitutive model has been proposed in this paper. Firstly, the triaxial creep test data indicated that, the strain-time (𝜀-t) curve showing in the 𝜀-lgt space can be divided into two lines with different slopes, and the time referring to the demarcation point is named as tEOP. Thereafter, the strain increments occurred after the time tEOP are totally assumed to be the creep components, and the elastic and plastic strains had occurred before tEOP. A hyperbolic equation expressing the relationship between creep volumetric strain, stress and time is proposed, with several triaxial creep test data of soft clays verifying the applicability. Additionally, the creep flow law is suggested to be similar with the plastic flow law of the modified Cam-Clay model, and the proposed volumetric strain equation is used to deduced the scaling factor for creep strains. Therefore, a creep constitutive model is thereby established, and verified by successfully predicting the creep principal strains of triaxial specimens.