• 한국전기전자재료학회논문지
• /
• 제29권11호
• /
• pp.720-724
• /
• 2016

Transparent n-type metal-oxide semiconductor of $MoO_x$ was applied on a p-type Si substrate for high-performing heterojunction photodetector. The formation of $MoO_x$ on Si spontaneously established a rectifying current flow with a high rectification ratio of 1,252.3%. Under light illumination condition, n-type $MoO_x$/p-type Si heterojunction device provided significantly fast responses (rise time : 61.28 ms, fall time : 66.26 ms). This transparent metal-oxide layer ($MoO_x$) would provide a functional route for various photoelectric devices, including photodetectors and solar cells.

• 디자인학연구
• /
• 제19권1호
• /
• pp.15-26
• /
• 2006

최근 고령화 사회 진입에 따라 고령 사용자의 컴퓨터 사용규모와 관심이 점점 증가하면서 컴퓨터의 사용성(usability)에 대한 유니버설 디자인 문제가 제 기되고 있으며, 특히 MS Windows의 유니버설 UI디자인의 중요성에 대한 인식도 커지고 있다. 따라서 본 연구는MS windows 사용에 있어 사용자의 나이, 능력에 상관없이 고령 사용자 및 컴퓨터 사용 초심자에게 보다 직관적이고 쉽게 사용할 수 있는 MS Windows의 유니버설 GUI 디자인의 개념을 설정하는 것을 목적으로 하였다. 특히, MS Windows의 학습과 사용에 있어 가장 어려움이 많을 것으로 예상되는 고령 사용자의 요구 사항을 조사, 분석하고 이 에 대한 해결안을 GUI 디자인에 반영하는 것을 중심으로 진행하였다. 연구 방법은 사용자 조사 방법으로서 고령자 대상의 컴퓨터 교육과정에서 MS Windows를 교육하는 4주 동안 보조 교사로 참여하여 관찰을 실시하였으며, 이를 보완할 수 있는 탐색 테스트와 인터뷰를 추가적으로 진행함으로써 불편 요소와 요구사항을 추출하였고 이를 기반으로 US Windows의 새로운 GUI 디자인 안을 제시하였다. 디자인 해결안은 MS Windows의 디폴트 값 설정, 쉬운 개념모형 형성을 위한 MS Windows 기능 단순화, 진화과정에 따른 MS Windows기능과 환경설정의 개인화, 화면에서의 시각적 문제 해결, 조작 과정상에서의 인터랙션 문제 해결 등의 방향에서 아이디어를 포함하였으며, MS Windows XP 환경에서 제공하는 사용자 로그인에서 사용자의 수준에 따라 초보자 모드로 접근 가능하여 운영 가능하도록 하였다. 본 연구는 고령 사용자의 MS Windows 활용에 대한 문제점과 요구사항을 장기적인 참여관찰을 통해 추출함으로써 신뢰도 높은 디자인 문제를 발견했다는데 의의를 찾을 수 있으며, 향후 해결안으로 제시된 디자인 안의 사용성에 대한 검증이 이루어져야 할 것이다.

• Journal of Advanced Marine Engineering and Technology
• /
• 제41권1호
• /
• pp.56-61
• /
• 2017

본 논문은 시간지연이 있는 데이터의 예측기법과 햅틱기반의 원격조작시스템에서의 응용방법을 다룬다. 일반적으로 네트워크 환경은 데이터 전송에 따른 시간지연이 필수적으로 동반되며, 햅틱기반의 원격조작시스템이 이러한 네트워크 환경에 구현되는 경우 시간지연으로 인해 전체 시스템의 성능저하를 피할 수 없다. 이러한 상황을 고려하여, 본 논문은 ARMA모델을 기반으로 모델파라미터의 학습방법과 실시간 예측을 위한 재귀적 알고리즘을 제안한다. 제안된 방법은 가상공간에 놓인 물체에 대하여 양방향 햅틱 상호작용의 상황에서 5ms의 샘플링 주기로 획득한 햅틱데이터에 적용되며, 그 결과로서 100ms 이후의 값을 예측함에 있어 위치수준 오차 1mm이내의 예측성능을 보였다.

• 한국식품영양과학회지
• /
• 제43권3호
• /
• pp.419-424
• /
• 2014

본 연구에서는 LC-MS/MS를 이용한 블루베리의 methanol과 ethyl acetate 추출 분획에 존재하는 대사체의 분석을 통해 효율적인 대사체 profiling의 가능성을 탐색하였다. LC-MS/MS에서 검출되는 대사체를 통계 처리한 결과, methanol 추출 분획에서는 5-O-feruloylquinic acid, malvidin hexoside, malvidin-3-arabinoside, petunidin-3-arabinoside, delphinidin hexoside, delphinidin, petunidin hexoside와 같은 안토시아닌 계열의 화합물들이 존재하였고, ethyl acetate 분획에서는 chlorogenic acid, chlorogenic acid dimer, 6,8-di-C-arabinopyranosylluteolin, luteolin과 같은 플라보노이드 계열의 화합물이 검출되었다. 본 연구는 기존 연구와 달리 대사체학 기법을 이용한 블루베리 추출물 전체 대사물질의 profiling을 시도한 최초의 연구로서 블루베리에 함유된 유용 성분의 스크리닝 등 향후 응용 연구에 유용한 기반으로 이용될 수 있을 것으로 기대된다.

• Bulletin of the Korean Chemical Society
• /
• 제29권9호
• /
• pp.1755-1760
• /
• 2008

Energy minimization and conformational studies of molecular ions generated by ESI (electrospray ionization) tandem mass spectrometry (MS/MS) can be used for the discrimination of stereoisomeric permethylated and sodium cationized trisaccharides. Sets of fucose-containing trisaccharides having different internal and terminal linkages have been synthesized to analyze the reducing terminal linkage positions using BT and IT fusion approaches. A detailed investigation has been undertaken on the conformational behaviors of four trisaccharide fragments from human milk and blood group determinants of Type 1 and Type 2, namely Fuc($\alpha$1- 3)Gal($\beta$1-3)GalNAc and Fuc($\alpha$1-3)Gal($\beta$1-X)GlcNAc where X = 3, 4 and 6 using molecular modeling methods. Three dimensional rigid and adiabatic phi-psi-energy maps (Surfer program) describing the energy as a function of rotation around corresponding glycosidic linkages were calculated by SYBYL molecular modeling and MM4 force field programs conjunction with cleavage energies of ESI MS/MS for the side group orientations. This approach predicted conformational behaviors exhibited by isomer saccharides for future applications on biologically active glycoconjugates and to exploit a faster method of synthesizing a series of structural isomeric oligosaccharides.

• Nutrition Research and Practice
• /
• 제6권4호
• /
• pp.328-333
• /
• 2012

This study was performed to investigate the differences in food choice, nutrition labeling perceptions, and prevalence of obesity due to meal skipping in Korean elementary school children. A national survey was performed in 2010 to collect data on food intake frequency, understanding of nutrition labeling, and body mass index from 2,335 fifth grade students in 118 elementary schools selected from 16 metropolitan local governments by stratified cluster sampling. The data were analyzed using the SAS 9.1 and SUDAAN 10.0 packages. Students who consumed three meals for 6-7 days during the past week were classified into the regular meal eating (RM) group (n = 1,476) and those who did not were placed into the meal skipping (MS) group (n = 859). The daily intake frequency of fruits, vegetables, kimchi, and milk was significantly lower in the MS group compared to that in the RM group (P < 0.001), whereas the daily intake frequency of soft drinks and instant noodles (ramyeon) was significantly higher in the MS group than that in the RM group (P < 0.05). The MS group demonstrated a significantly lower degree of understanding with regard to nutrition labeling and high calorie foods containing low nutritional value than that in the RM group. The distribution of obesity based on the percentile criteria using the Korean growth chart was different between the MS and RM groups. The MS group (8.97%) had a higher percentage of obese subjects than that in the RM group (5.38%). In conclusion, meal skipping was related to poor food choice, low perception of nutrition labeling, and a high prevalence of obesity in Korean fifth grade children.

• Parasites, Hosts and Diseases
• /
• 제49권3호
• /
• pp.295-298
• /
• 2011

Lactobacillus species in the female genital tract are thought to act as a barrier to infection. Several studies have demonstrated that lactobacilli can adhere to vaginal epithelial cells. However, little is known about how the adherence of lactobacilli to vaginal epithelial cells affects the acidity, cell viability, or proliferation of the lactobacilli themselves or those of vaginal epithelial cells. Lactobacillus acidophilus was co-cultured with immortalized human vaginal epithelial cells (MS74 cell line), and the growth of L. acidophilus and the acidity of the culture medium were measured. MS74 cell density and viability were also assessed by counting cell numbers and observing the cell attachment state. L. acidophilus showed exponential growth for the first 6 hr until 9 hr, and the pH was maintained close to 4.0-5.0 at 24 hr after culture, consistent with previous studies. The growth curve of L. acidophilus or the pH values were relatively unaffected by co-culture with MS74 cells, confirming that L. acidophilus maintains a low pH in the presence of MS74 cells. This co-culture model could therefore potentially be used to mimic vaginal conditions for future in vitro studies. On the other hand, MS74 cells co-cultured with L. acidophilus more firmly attached to the culture plate, and a higher number of cells were present compared to cells cultured in the absence of L. acidophilus. These results indicate that L. acidophilus increases MS74 cell proliferation and viability, suggesting that lactobacilli may contribute to the healthy environment for vaginal epithelial cells.

• 분석과학
• /
• 제34권5호
• /
• pp.193-201
• /
• 2021

We have demonstrated a sensitive analytical method of measuring oleracone D in mouse plasma using a liquid chromatography-tandem mass spectrometry (LC-MS/MS). Oleracone D and oleracone F (internal standard) in mouse plasma samples were processed using a liquid-liquid extraction method with methyl tertbutyl ether, resulting in high and reproducible extraction recovery (80.19-82.49 %). No interfering peaks around the peak elution time of oleracone D and oleracone F were observed. The standard calibration curves for oleracone D ranged from 0.5 to 100 ng/mL and were linear with r² of 0.992. The inter- and intra-day accuracy and precision and the stability fell within the acceptance criteria. The pharmacokinetics of oleracone D following intravenous and oral administration of oleracone D at doses of 5 mg/kg and 30 mg/kg, respectively, were investigated. When oleracone D was intravenously injected, it had first-order elimination kinetics with high clearance and volume of distribution values. The absolute oral bioavailability of this compound was calculated as 0.95 %, with multi-exponential kinetics. The low aqueous solubility and a high oral dose of oleracone D may explain the different elimination kinetics of oleracone D between intravenous and oral administration. Collectively, this newly developed sensitive LC-MS/MS method of oleracone D could be successfully utilized for investigating the pharmacokinetic properties of this compound and could be used in future studies for the lead optimization and biopharmaceutic investigation of oleracone D.

• Journal of Animal Science and Technology
• /
• 제62권6호
• /
• pp.790-800
• /
• 2020

The Yeonsan Ogye (YO) chicken is a natural heritage of Korea, characterized by black feathers, skin, bones, eyes, and comb. The purebred of YO population has been reared under the natural mating system with no systematic selection and breeding plan. The purpose of this study was to identify the genetic diversity and find the optimal number of population sub-division using 12 polymorphic microsatellite (MS) markers to construct a pedigree-based breeding plan for the YO population. A total of 509 YO birds were used for this study. Genetic diversity and population structure analysis were conducted based on the MS marker genotype information. The overall average polymorphic information content value and expected heterozygosity of the population were 0.586, and 0.642, respectively. The K-mean cluster analysis based on the genetic distance result confirmed that the current YO population can be divided into three ancestry groups. Individuals in each group were evaluated based on their genetic distance to identify the potential candidates for a future breeding plan. This study concludes that a future breeding plan with known pedigree information of selected founder animals, which holds high genetic diversity, could be the best strategy to ensure the conservation of the Korean YO chicken population.

• 한국정보기술응용학회:학술대회논문집
• /
• 한국정보기술응용학회 2005년도 6th 2005 International Conference on Computers, Communications and System
• /
• pp.73-76
• /
• 2005

The advanced information and communication technology gives vehicles another role of the third digital space, merging a physical space with a virtual space in a ubiquitous society. In the ubiquitous environment, the vehicle becomes a sensor node, which has a computing and communication capability in the digital space of wired and wireless network. An intelligent vehicle information system with a remote control and diagnosis is one of the future vehicle systems that we can expect in the ubiquitous environment. However, for the intelligent vehicle system, many issues such as vehicle mobility, in-vehicle communication, service platform and network convergence should be resolved. In this paper, an in-vehicle gateway is presented for an intelligent vehicle information system to make an access to heterogeneous networks. It gives an access to the server systems on the internet via CDMA-based hierarchical module architecture. Some experiments was made to find out how long it takes to communicate between a vehicle's intelligent information system and an external server in the various environment. The results show that the average response time amounts to 776ms at fixec place, 707ms at rural area and 910ms at urban area.