• Title/Summary/Keyword: Functional sensitivity

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Fluorescent Nanoparticles: Synthesis and Applications (형광 나노입자: 합성 및 응용)

  • Kim, Y.K.;Song, B.K.;Lee, J.G.;Baek, Y.K.
    • Journal of Powder Materials
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    • v.27 no.2
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    • pp.154-163
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    • 2020
  • Fluorescent nanoparticles are characterized by their unique properties such as luminescence, optical transparency, and sensitivity to various chemical environments. For example, semiconductor nanocrystals (quantum dots), which are nanophosphors doped with transition metal or rare earth ions, can be classified as fluorescent nanoparticles. Tuning their optical and physico-chemical properties can be carried out by considering and taking advantage of nanoscale effects. For instance, quantum confinement causes a much higher fluorescence with nanoparticles than with their bulk counterparts. Recently, various types of fluorescent nanoparticles have been synthesized to extend their applications to other fields. In this study, State-of-the-art fluorescent nanoparticles are reviewed with emphasis on their analytical and anti-counterfeiting applications and synthesis processes. Moreover, the fundamental principles behind the exceptional properties of fluorescent nanoparticles are discussed.

A Boundary Method for Shape Design Sensitivity Analysis for Shape Optimization Problems and its Application (경계법을 이용한 형상최적화 문제의 설계민감도 해석 및 응용)

  • 최주호;곽현구
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2004.10a
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    • pp.355-362
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    • 2004
  • An efficient boundary-based technique is developed for addressing shape design sensitivity analysis in various problems. An analytical sensitivity formula in the form of a boundary integral is derived based on the continuum formulation for a general functional defined in problems. The formula, which is expressed in terms of the boundary solutions and shape variation vectors, can be conveniently used for gradient computation in a variety of shape design problems. While the sensitivity can be calculated independent of the analysis means, such as the finite element method (FEM) or the boundary element method (BEM), the FEM is used for the analysis in this study because of its popularity and easy-to-use features. The advantage of using a boundary-based method is that the shape variation vectors are needed only on the boundary, not over the whole domain. The boundary shape variation vectors are conveniently computed by using finite perturbations of the shape geometry instead of complex analytical differentiation of the geometry functions. The supercavitating flow problem and fillet problem are chosen to illustrate the efficiency of the proposed methodology. Implementation issues for the sensitivity analysis and optimization procedure are also addressed in these problems.

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Korean Mothers' Intuitive Theories Regarding Emotion Socialization of their Children

  • Park, Seong-Yeon;Trommsdorff, Gisela;Lee, Eun-Gyoung
    • International Journal of Human Ecology
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    • v.13 no.1
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    • pp.39-56
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    • 2012
  • This study aims at exploring Korean mothers' beliefs on the development of emotion of their children. In specific, sensitivity and maternal reactions to their children's both negative and positive emotion expressions were explored. Further, associations among maternal sensitivity, maternal reactions and child emotion regulation were examined. A total of 100 Korean mothers whose children were between 6 and 7 years old participated in the study. In order to assess mothers' beliefs about sensitivity, vignettes in a forced-choice format were presented through individual interviews. Mothers' self reported reactions to their children's negative emotions and positive emotions and mothers' perceptions of children's emotion regulation were assessed using questionnaires. Results revealed that Korean mothers endorsed both proactive and reactive sensitivity. However, their sensitivity differed depending on the situation. Mothers tended to endorse either Emotion Focused or Problem Focused reactions to their children's negative emotions. Mothers reported that they were most likely to restrict their child positive emotional expression with explanation in supportive way followed by invalidating through reprimanding it. Mothers' reported Distress Reactions and Punitive Reactions to children's expression of negative emotion were associated with children's liability whereas Emotion-Focused Reaction and Problem-Focused Reaction were associated with children's functional emotion regulation. The results are discussed within a theoretical framework of socialization of emotions.

Shape Design Sensitivity Analysis of Supercavitating Flow Problem (초공동(超空洞) 유동 문제의 형상 설계민감도 해석)

  • Choi, J.H.;Gwak, H.G.;Grandhi, R.
    • Proceedings of the KSME Conference
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    • 2004.04a
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    • pp.1047-1052
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    • 2004
  • An efficient boundary-based technique is developed for addressing shape design sensitivity analysis in supercavitating flow problem. An analytical sensitivity formula in the form of a boundary integral is derived based on the continuum formulation for a general functional defined in potential flow problems. The formula, which is expressed in terms of the boundary solutions and shape variation vectors, can be conveniently used for gradient computation in a variety of shape design in potential flow problems. While the sensitivity can be calculated independent of the analysis means, such as the finite element method (FEM) or the boundary element method (BEM), the FEM is used for the analysis in this study because of its popularity and easy-touse features. The advantage of using a boundary-based method is that the shape variation vectors are needed only on the boundary, not over the whole domain. The boundary shape variation vectors are conveniently computed by using finite perturbations of the shape geometry instead of complex analytical differentiation of the geometry functions. The supercavitating flow problem is chosen to illustrate the efficiency of the proposed methodology. Implementation issues for and optimization procedure are addressed in this flow problem.

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Predictive Analysis on Explosive Performance and Sensitivity of 1-Substituted Trinitroimidazoles (트리나이트로이미다졸 치환체들의 화약성능 및 감도 예측 분석)

  • Jeon, Yeongjin;Kim, Hyoun-Soo;Kim, Jin Seuk;Cho, Soo Gyeong
    • Journal of the Korea Institute of Military Science and Technology
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    • v.20 no.4
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    • pp.543-550
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    • 2017
  • Various chemical properties including density and heat of formation of 1-substitued trinitroimidazoles (TNIs) were estimated by using density functional theory (DFT). Using chemical properties estimated by DFT, explosive performance and sensitivity of 1-substitued TNIs were analyzed by following the ADD Method-1 procedure. The results were displayed on two-dimensional performance-sensitivity plot, and were compared with those of explosive molecules commonly used in many military systems. Different 1-substituents of TNI made that both explosive performance and impact sensitivity were changed significantly. Methyl substituted TNI became moderately insensitive and slightly less powerful. Amino, fluoro, picryl, and difluoroamino substituted TNIs were highly powerful like RDX and HMX, but greatly sensitive. Nitro substituted TNI was predicted to be extremely sensitive to be handled as a secondary explosive.

A Novel Behavior, Bang-Sensitive Paralysis, Associated With The shibire Locus of Drosophila melanogaster

  • 김윤택
    • Environmental Mutagens and Carcinogens
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    • v.10 no.2
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    • pp.93-106
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    • 1990
  • The Drosophila temperature-sensitive mutant shibire (shi) is paralyzed at restrictive temperature by a reversible block in synaptic transmission. To explore the functional relationship among shi gene products, viability and temperature-sensitive paralytic behavior were quantitaively analyzed for four shi alleles, shi$^{ts1}$, shi$^{ts2}$, shi$^{ts4}$, and shi$^{ST139}$, and their heteroallelic combinations. The hemizygous combination of shi alleles over deficiency was not completely lethal. shi$^{ts2}$ exhibited distinctively higher viability than other alleles. A novel behavior, bang sensitivity, was also found in shi/Df(1). This bang-sensitive paralytic behavior was compared with that of the typical bang-sensitive mutant flies. Heterozygotes, shi/+, are more severe in temperature sensitivity than deficiency hemizygotes, Df(1)/+. Heteroallelic combinations of shi were less sensitive to high temperature than homozygotes. Among all allelic combinations, shi$^{ts2}$/shi$^{ts4}$ showed an unexpected extreme reduction in temperature sensitivity. The results of allelic interactions among 4 shi alleles suggest that the shi mutations examined behave as antimorphic alleles and that the gene product of shi are likely to function in multimeric forms.

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A NON-ITERATIVE RECONSTRUCTION METHOD FOR AN INVERSE PROBLEM MODELED BY A STOKES-BRINKMANN EQUATIONS

  • Hassine, Maatoug;Hrizi, Mourad;Malek, Rakia
    • Journal of the Korean Mathematical Society
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    • v.57 no.5
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    • pp.1079-1101
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    • 2020
  • This work is concerned with a geometric inverse problem in fluid mechanics. The aim is to reconstruct an unknown obstacle immersed in a Newtonian and incompressible fluid flow from internal data. We assume that the fluid motion is governed by the Stokes-Brinkmann equations in the two dimensional case. We propose a simple and efficient reconstruction method based on the topological sensitivity concept. The geometric inverse problem is reformulated as a topology optimization one minimizing a least-square functional. The existence and stability of the optimization problem solution are discussed. A topological sensitivity analysis is derived with the help of a straightforward approach based on a penalization technique without using the classical truncation method. The theoretical results are exploited for building a non-iterative reconstruction algorithm. The unknown obstacle is reconstructed using a levelset curve of the topological gradient. The accuracy and the robustness of the proposed method are justified by some numerical examples.

A Predictive Study on Molecular and Explosive Properties of 1-Aminoimidazole Derivatives

  • Cho, Soo-Gyeong
    • Bulletin of the Korean Chemical Society
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    • v.32 no.7
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    • pp.2319-2324
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    • 2011
  • Molecular structures and chemical properties of 1-aminoimidazole derivatives have been investigated at high levels of density functional theories. Heat of formation, density, explosive performances and impact sensitivities have been estimated at the global minimum of potential energy surface. As more nitro groups are introduced, the explosive performances of 1-aminoimidazole derivatives are enhanced, while the impact sensitivity becomes more sensitive. A two-dimensional plot between explosive performance and impact sensitivity has been utilized to comprehend the technical status of new explosive candidates. Based on locations in the two-dimensional plot, 1-aminodinitroimidzole isomers appears to have a potential to be good candidates for insensitive explosives, and 1-aminotrinitroimidazole may become a powerful explosive molecule whose behavior is quite close to HMX.

Sensitivity Analysis of the Zigzag Switch under Acceleration and Centrifugal Forces (가속력과 원심력을 받는 지그잭 스위치의 민감도 해석)

  • 김경환
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1996.11a
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    • pp.1067-1072
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    • 1996
  • Sensitivity analysis of the cylindrical zigzag cams under acceleration and centrifugal forces is performed. A Lagrangian method is used to determine the mechanism constant of zigzag track, And the equation of motion for cylindrical zigzag cam under rectangular pulse is derived by the governing equations of a single spring mass system. The ratio of the drive force tn resisting force is derived by angular acceleration, centrifugal force and setback force on the operation of the munition. The theoretical sensitivity curves for 3 models are analyzed. And experiments for 3 models are conducted to check safe and functional zone. Zigzag cam types can be satisfied all major design requirements for switch system of munition.

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A conditional lethal mutation of a nucleoporin gene, NUP49 in saccharomyces cerevisiae

  • Lee, Youn-Soo;Song, Young-Ja;Kyung, Hwang-Mi;Lee, Woo-Bok;Kim, Jin-Mi
    • Journal of Microbiology
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    • v.35 no.3
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    • pp.234-238
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    • 1997
  • Conditional lethal mutation nup49-1 of a nuclear pore complex component gene was constructed in Saccharomyces cerevisiae. This mutation deleted one third of the essential NUP49 gene at the carboxy-terminal, but retained 13 repeats of the highly conserved GLFG domain. The nup49-1 mutant strain was viable with a slow-growth phenotype, indicating that the C-terminal is dispensable at normal growth temperature. This strain exhibited both temperature-sensitivity at 37.deg.C and cold-sensitivity at 16.deg.C. Temperature shift experiments revealed that the arrest phenotype at 37.deg.C was random in the cell division cycle. The nup49-1 mutation was tested to be recessive and is expected to be useful for the functional analysis of nuclear pore complex proteins as well as for studies of nuclear transport systems.

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