• 한국식품위생안전성학회지
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• 제35권3호
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• pp.252-260
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• 2020

본 연구는 특수용도식품에 함유되어 있는 비타민B₁₂와 비오틴에 대하여 식품의 복잡한 매질 특성에 특이성을 확보할 수 있도록 현행 식품공전 시험법을 개선하고자 하였다. 식품공전에서 비타민B₁₂와 비오틴의 시험법에 항체반응을 통해서 분석물질과 특이적으로 결합하여 그 외의 성분들을 효과적으로 제거할 수 있는 면역친화성 컬럼을 도입하여 시험용액을 정제 및 농축함으로써 전처리 과정을 개선하였다. 식품 등 시험법 마련 표준절차에 관한 가이드라인에 따라 밸리데이션(특이성, 직선성, 검출한계, 정량한계, 정확도, 정밀도)을 수행하고 개선된 시험법을 이용하여 유통 중인 특수용도식품의 대상 품목에 대해 시험법 적용여부를 확인하였다. 본 연구사업의 수행으로 시험·검사의 정확성을 증대시켜 특수용도식품 품질관리에 대한 신뢰성을 더 높일 것으로 본다.

• 한국안전학회지
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• 제16권3호
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• pp.125-134
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• 2001

The Advanced Pressurized rater Reactor 1400(APR1400) system is advanced of the successful Korean Nuclear Power Plants(KSNP) design which meets functional needs for safety enhancement reliability improvement, and control in the human-computer monitoring system. Therefore this paper describes the scoring model in order to justify the reliability and safety in APR 1400 under uncertainty. The structure of this paper consists of the human engineering, risk safety, quality function, safety organization management factors of the qualitative factors in chapter 2, and the expectation results of the normalized scoring model in chapter 3. Finally, the proposed reliability model have provided the technical flexibility not only for functional control fields but also for accidents protection systems in APR 1400 under uncertainty.

• 한국식품위생안전성학회지
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• 제34권5호
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• pp.431-437
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• 2019

본 연구는 건강기능식품 프랑스해안송껍질추출물 중 catechin, caffeic acid, ferulic acid, taxifolin에 대한 동시분석법을 개발하는 연구이다. 최적분석조건을 확립하기 위해 시료 채취량, 용매 조건을 비교 검토하였으며, UPLC-MS/MS를 이용하여 각 4개 성분에 대한 정확한 분석 및 분석시간의 효율성도 향상하였다. 분석 시 사용한 컬럼은 Acquity UPLC BEH $C_{18}$이며, 정량이온으로 catechin, caffeic acid, ferulic acid, taxifolin 각각 133, 135, 245 및 248을 선정하였다. 확립된 시험법에 대해 특이성, 직선성, 검출한계, 정량한계, 정확성, 정밀성 등의 밸리데이션을 수행하였다. 4개 성분 모두 50-25000 mg/L 농도에서 결정계수(R2) 0.999이상으로 높은 직선성을 확인하였다. 또한 회수율은 84.9-104%이었고, 정밀성은 1.2-4.3%의 RSD를 확인하였다. 개발된 시험법은 프랑스해안송껍질추출물 중 catechin, caffeic acid, ferulic acid, taxifolin 분석을 위한 시험법으로 활용되기에 적합한 것으로 판단된다.

• 시스템엔지니어링학술지
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• 제13권1호
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• pp.57-65
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• 2017

Recently, the ratio of electrical part and embedded software has grown in automotive industry. ISO 26262, 'Road Vehicles - Functional Safety', was published to guide development of automotive electrical and electronic part in 2011. This paper describes definition of functional safety and analyzes ISO 26262. The comparison of ISO 26262 and DO-178C is made, then difference between them is identified. DO-178C provides guidance for the production of software for airborne system and equipment. The core of DO-178C is a relatively minor update to the previous DO-178B, however, the big changes are captured in the supplemented documents such as DO-331, 'Model-Based Development and Verification Supplement to DO-178C and DO-278A'. Model-based design is important to develop automotive and aircraft meeting the guidelines of ISO 26262 and DO-178C. In this paper, the sample case of applying MBSE(Model-Based Systems Engineering) to AVCS(Active Vibration Control System) software development is discussed.

• 품질경영학회지
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• 제41권2호
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• pp.185-196
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• 2013

Purpose: This paper is focused on introducing the Automotive Functional Safety International Standard-ISO 26262 and proposing effective countermeasures of ISO 26262. Methods: We studied collected data about ISO 26262 and analyzed the relationship between ISO 26262 and Quality 5 Star of Hyundai Kia Motors for the integrated product development process. Results: Results showed the product development process for the integration plan between ISO 26262 and Quality 5 Star. In addition, we added an entry about the functional safety in the evaluation item of Quality 5 Star System. Conclusion: In order to introduce ISO 26262 effectively, we proposed ISO 26262 requirements and functional safety concept to be added to Quality 5 Star.

• 한국항행학회논문지
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• 제19권1호
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• pp.41-47
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• 2015

최근 국내에서 A-SMGCS (advance surface movement ground control systems) 레벨 IV단계를 구현하기 위한 연구가 활발히 진행 중에 있다. 전체 A-SMGCS 시스템의 안전을 확보하기 위하여 안전성 평가가 필요하며, 유로컨트롤에서는 A-SMGCS의 안전성 평가를 위하여 기능별 위험요소 평가, 예비시스템 안전성 평가, 그리고 시스템 안전성 평가를 수행하도록 권고하고 있다. 본 논문에서는 기능별 위험요소 평가 방법을 통하여 전체 A-SGMCS의 위험요소를 식별한다. 따라서 A-SMGCS레벨 IV시스템에 대하여 29가지 위험 요소를 식별하고 각 위험요소의 심각도를 평가하는 자료로 활용할 것이다.

• 대한안전경영과학회지
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• 제15권4호
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• pp.161-169
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• 2013

Due to the recent advances in technology, the systems are becoming more demanding in terms of functionality and implementation complexity. Therefore, when system failures are involved in such complex systems, the effects of the related safety issues can also be more serious, thereby causing in the worst case irrecoverable hazards on both human being and properties. This fact can be witnessed in the recent rail systems accidents. In general, the accidents can be attributed to the systematic failure or the random failure. The latter is due to the aging or unsatisfied quality of the parts used in implementation or some unexpected external cause that would otherwise result in accidents whereas the former is usually related to incomplete systems design. As the systems are becoming more complex, so are the systematic failures. The objective of the paper is to study an approach to solving the systematic failure. To do so, at first the system design process is augmented by the functional safety activities that are suggested in the standard IEC 61508. Analyzing the artifacts of the integrated process yields the traceability, which satisfies the requirements for reduction of systematic failure as provided in ISO 26262. In order to reduce systematic failure, the results are utilized in the conceptual design stage of systems development in which systems requirements are generated and functional architecture is developed.

• 한국의상디자인학회지
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• 제24권4호
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• pp.101-116
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• 2022

The purpose of this study is to understand the trends of fashion mask designs as a fashion item with characteristics to protect individual health and safety from harmful environments. To this end, the concept, the trend analysis of the domestic and foreign mask markets, the type, characteristics of functional masks, and the design trend of fashion masks were analyzed. Research methods included case studies and literaturte on mask design, fashion magazines, fashion brand websites, fashion collections, and promotional material. First, masks for personal safety were classified as protective function masks from the natural environment, functional masks by industrial groups, masks for protective functions from biohazards, and masks for protective functions from various external activities. Through this analysis, the design trends of fashion masks were analyzed. The functional orientation of structure and functionality, the environmental orientation of sustainable eco-friendly methods, the fashion orientation of individual fashion styling, and the social functional orientation tend to transmit social messages. In the harmful environment of everyday life, items such as fashion masks with functionality and fashion characteristics should be continuously studied to integrate functional and design characteristics that can contribute to the future fashion industry and the fashion market as a sense of unity and responsibility.

• 한국식품위생안전성학회지
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• 제7권4호
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• pp.153-163
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• 1992

Dietary fiber imparts both mutritional and functional properties to foods. This review deals with (1) the classification of dietary fiber, (2) the plant cell wall models, (3) the relations between structure and physicochemical and functional properties of dietary fiber and (4) the applications of dietary fiber in foods. Dietary fiber can be classified in terms of source, plant function, solubility, charge and topology. Plant cell wall models are presented to provide information on the interconnections of dietary fiber components which determines the content of soluble and insoluble dietary fiber content. In reality, physicochemical and functional properties of dietary fiber originate factors such as chemical constituents , charge, branching degree, conformation and etc. Dietary fibers possess a variety of functional properties in food systems, which thus make them useful in food application. In particular, rheology and gelation of water-soluble gums or hydrocolloids are discussed for their effects on food quality. A guideline s also listed for the gum selection to meet the best product requirements.

• Nuclear Engineering and Technology
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• 제51권5호
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• pp.1289-1296
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• 2019

Non-functional requirements plays a critical role in designing variety of applications domain ranges from safety-critical systems to simple gaming applications. Performance is one of the crucial non-functional requirement, especially in control and safety systems, that validates the design. System risk can be quantified as a product of probability of system failure and severity of its impact. In this paper, we devise a technique to do the performance analysis of safety critical and control systems and to estimate performance based risk factor. The technique elaborates Petri nets to estimate performability to ensure system dependability requirements. We illustrate the technique on a case study of Nuclear Power Plant system. The technique has been validated on 17 safety critical and control systems of Nuclear Power Plant.