• 대한의생명과학회지
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• 제12권3호
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• pp.185-190
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• 2006

Lysyl oxidase (LOX) catalyzes the lysine-derived cross-links of fibrillar collagens and elastin in the extracellular matrix. Recent molecular cloning has revealed existence of a LOX family consisting of LOX and four lysyl oxidase-like proteins (LOXL, LOXL2, LOXL3 and LOXL4). Pathological conditions associated with impaired LOX activity in several heritable and acquired disorders lead to severe structural and functional abnormalities of cardiovascular tissues, such as occlusion of coronary arteries and aneurysms, suggesting an essential role for the LOX family proteins in the maintenance of the cardiovascular system. However, the specific roles of the lysyl oxidase-like proteins in normal and pathological conditions of the cardiovascular tissues have not been established yet. Here, I report that LOXL3, a novel member of the LOX family, is predominantly expressed in the aorta, with an amine oxidase activity toward collagen and elastin, suggesting an essential role of LOXL3 in the development and maintenance of the aorta.

• 반도체디스플레이기술학회지
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• 제16권1호
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• pp.52-58
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• 2017

Graphene oxide (GO)/carboxylated styrene-butadiene rubber (XSBR) nanocomposites with various contents of GO were prepared by a latex compounding method. It has been confirmed that the functional groups of GO and the hydrogen bonds between GO and XSBR are existed. It can be seen that the scorch time ($t_{s2}$), which is the measurement of incipient vulcanization of rubber, showed a delay after the addition of GO. Field emission scanning electron microscopy was employed to confirm the uniform dispersion of filler in the matrix. Indeed, with increasing fillers loading, the torque, tensile strength, thermal stability and crosslink density of obtained nanocomposites were improved. These results were correlated to the better dispersion of fillers through the rubber matrix.

• 대한조선학회지
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• 제25권3호
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• pp.3-12
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• 1988

A natural or an artificial harbor can exhibit frequency(or period) dependent water surface oscillations when excited by incident waves. Such oscillations in harbors can cause significant damage to moored ships and adjacent structures. This can also induce undesirable current in harbors. Many previous investigators have studied various aspects of harbor resonance problem. In the percent paper, both a localizes finite element method(LFEM) which is based on the functional constructed by Chen & Mei(1974) and Bai & Yeung(1974) and an integral equation method which was used by Lee(1969) are applied to harbor resonance problem. The present method(LFEM) shows computationally more efficient than the integral equation method. Our test results shows good agreement compared with other results. This enhanced computational efficiency is due to the fact that the present method gives a banded symmetric coefficients matrix and requires much less computational time in the calculation of the influence coefficients matrix than the integral equation method involved with Green's function. To test the present numerical scheme, two models are treated here. The present method(LFEM) can be extended to a fully three dimensional harbor problem with the similar computational advantage.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2018년도 추계 학술논문 발표대회
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• pp.29-30
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• 2018

The development of the industry has increased the indoor living time of modern people. Therefore, indoor pollution is attracting attention as a social issue. One of the indoor air pollution is formaldehyde. Formaldehyde has been classified as a first-level carcinogen by international cancer research organizations. Formaldehyde has been used to protect products such as construction materials and finish materials, and being diffused in the interior construction process. In this study, we used phytoncide with cement matrix to reduce formaldehyde, an indoor environmental contaminant. The strengths was increased slightly and formaldehyde showed a reduction effect over time.

• 전기학회논문지
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• 제60권11호
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• pp.2103-2108
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• 2011

In this paper, the problem of passivity analysis for neural networks with time-varying delays and norm-bounded parameter uncertainties is considered. By constructing a new augmented Lyapunov functional, a new delay-dependent passivity criterion for the network is established in terms of LMIs (linear matrix inequalities) which can be easily solved by various convex optimization algorithms. Two numerical example are included to show the effectiveness of proposed criterion.

• 전기학회논문지
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• 제58권9호
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• pp.1809-1814
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• 2009

In this paper, the problem of stability analysis for neural networks with discrete and distributed time-varying delays is considered. By constructing a new Lyapunov functional, a new delay-dependent stability criterion for the network is established in terms of LMIs (linear matrix inequalities) which can be easily solved by various convex optimization algorithms. Two numerical example are included to show the effectiveness of proposed criterion.

• Asia pacific journal of information systems
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• 제9권1호
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• pp.17-38
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• 1999

While the value of information technology has long been a hot issue, few solid results have been found as of yet. It is partly due to methodological factors and model underspecifcation. This study empirically develops a ITS(information technology structure) taxonomy and investigates the relationships between ITS taxonomy and business performance in the Korean firms. Among factors that impact business performance, organization structure and control system are selected and they are hypothesized to moderate-the relationships between ITS taxonomy and business performance. By surveying 91 manufacturing firms and applying hierarchical cluster analysis, four ITS are identified : centralized, decentralized, centralized cooperative, decentralized cooperative. ANOVA, correlation analysis and crosstable analysis say the presence of moderating effect of organization structure and control system. Cooperative ITS is best in business performance. Centralized ITS is related to functional organizational form. Decentralized ITS is related to product organizational form with decentralized decision making, Centralized cooperative ITS is related to matrix organizational form. Decentralized cooperative ITS is related to matrix organizational form with high integration. These findings have implications for the opportunities and challenges to match information technology with organization structure and control system.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2006년도 추계학술대회 학술발표 논문집 제16권 제2호
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• pp.293-296
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• 2006

This paper presents new sufficient conditions to an intelligent digital redesign (IDR). The purpose of the IDR is to effectively convert an existing continuous-time fuzzy controller to an equivalent sampled-data fuzzy controller in the sense of the state-matching. The state-matching error between the closed-loop trajectories is carefully analyzed using the integral quadratic functional approach. The problem of designing the sampled-data fuzzy controller to minimize the state-matching error as well as to guarantee the stability is formulated and solved as the convex optimization problem with linear matrix inequality (LMI) constraints.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.304.2-304.2
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• 2002

In central nervous system. matrix metalloproteinases (MMPs) are produced by neuron as well as glia and implicated in physiological events such as neurite outgrowth and myelination etc. In addition. MMPs also contribute to the pathogenesis of several CNS diseases such as multiple sclerosis, Alzheimer's disease and malignant glioma. In spite of their functional importance, little is known about the signal transduction pathways leading to the induction of MMPs in CNS. Here. we investigated whether the activation of Erk(1/2) is involved in the induction of MMP-9 in LPS-stimulated primary astrocytes. (omitted)

• Communications for Statistical Applications and Methods
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• 제28권3호
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• pp.233-250
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• 2021

This paper studies if the accuracies of mortality models (LC model vs. 4-parametric model) are aggravated if a mortality structure changes due to the impact of COVID-19. LC model (LCM) uses dimension reduction for fitting to the log mortality matrix so that the performance of the dimension reduction method may not be good when the matrix structure changes. On the other hand, 4-parametric factor model (4-PFM) is designed to use factors for fitting to log mortality data by age groups so that it would be less affected by the change of the mortality structure. In fact, the forecast accuracies of LCM are better than those of 4-PFM when life-tables are used whereas those of 4-PFM are better when the mortality structure changes. Thus this result shows that 4-PFM is more reliable in performance to the structural changes of the mortality. To support the accuracy changes of LCM the functional aspect is explained by computing eigenvalues produced by singular vector decomposition