• Radiation Oncology Journal
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• v.33 no.3
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• pp.261-264
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• 2015

External beam radiotherapy can be used to treat cutaneous squamous cell carcinomas (SCC). Acute skin toxicity is the most common adverse event. In this case study we report on an elderly patient with nasal root cutaneous SCC treated with stereotactic technique using a dedicated linear accelerator (CyberKnife system). Grade 3 skin toxicity was observed but it was resolved after 6 weeks. The use of stereotactic radiotherapy permitted a clinical remission of SCC with good cosmetic results.

• Proceedings of the Korean Society of Sericultural Science Conference
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• 2003.10a
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• pp.53-54
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• 2003

The silk fibroin has been widely used as industrial materials such as cosmetics and food l)-2). In this study, general hydrolysate of B. mori fibroin as a biomaterial, development of functional-cometics included hydrolysate of B. mori fibroin will be discussed. (omitted)

• KSBB Journal
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• v.27 no.4
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• pp.222-226
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• 2012

In this study, the effect of gamma irradiation on the microbial contamination and biological activities of tuna cooking juices was investigated. Tuna cooking juice was by-produced during the canning processing, and had various functional components. But, it was shown that the tuna cooking juice was seriously contaminated. Gamma irradiation effectively reduced the microbial population in tuna cooking juice. Also, 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging activity, tyrosinse inhibitory activity, and ACE inhibitory activity of tuna cooking juices were all increased as a result of gamma irradiation. These results suggest that wasted tuna cooking juices can be used as a functional component in the food and cosmetic industries if the irradiation technology were applied.

• Macromolecular Research
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• v.16 no.7
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• pp.631-636
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• 2008

The intrinsic viscosities were determined for poly(DL-lactic acid) (PDLLA) solutions in 1,2-dialkyl phthalate at temperatures ranging from 30 to $60^{\circ}C$. A series of dialkyl phthalate, in which the alkyl group was changed from methyl to propyl, was used as the solvent to control the solvent quality systematically. The intrinsic viscosity of the PDLLA solution was higher in the better quality solvent, with a higher molecular weight of PDLLA, and at lower temperatures. The unperturbed dimensions of the PDLLA molecule and polymer-solvent interaction parameter of PDLLA in dialkyl phthalate were deduced using extrapolation methods based on the temperature-dependent intrinsic viscosities. Slight shrinkage in the unperturbed chain dimension was observed, which resulted from a change in polymer conformation with temperature. It was also observed that the polymer-solvent interaction became more favorable with the dialkyl phthalate containing a shorter alkyl chain.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.77-77
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• 2019

Herbal medicines have been used as a basic means of clinical trial throughout history, and traditional medicines are targeted to seek functional components. To discover new cosmetic or food ingredients among numerous natural resources from Jeju island, we screened for inhibition activity against nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Although NO formation plays an important role to relax vascular muscles or eliminate tumors, NO produced excessively in inflammatory condition can cause metabolic diseases or inflammatory dysfunctions. Among 52 natural resources ethanol extracts, 5 extracts inhibited NO production over 25% compared to only LPS-treated control at the concentration of $100{\mu}g/mL$. In further study, we try to investigate other bio-activities and the phytochemicals of 5 different extracts as useful ingredients for cosmetics or functional foods.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.3
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• pp.209-217
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• 2012

One of the popular formulations is microemulsion in cosmetics. A kind of microemulsions is liquid crystal emulsion. Liquid crystal emulsion is used by wrapping functional ingredients. As the meaning of the name, Liquid crystals (LCs) are a state of matter that has properties between those of a conventional liquid and those of a solid crystal. There are various types of Liquid crystals (LCs) consisting of micelles or two layer structures of surfactants. Recently, microemulsion has been studied to improve its stability in thermodynamics of colloid science field. In this study, we prepared the microemulsion with PEG-8 Capryliccapric Glycerides and Polyglyceryl-3 Diisostearate. We studied the microemulsion with different oil types and different and cosurfactant content ratio. Also, the aim of this study is to develop a facial oil or a cleansing oil containing liquid crystal emulsion with functional ingredients.

• Korean Journal of Medicinal Crop Science
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• v.26 no.2
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• pp.119-126
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• 2018

Background: The flowering plant Hippophae rhamnoides L. has been used for many studies on fruit or leaf extracts. This study was conducted to investigate the development of a new cosmetic material from H. rhamnoides fruits and leaves that have by antioxidant, anti-inflammatory and wrinkle improvement activities. Methods and Results: The antioxidant abilities of H. rhamnoides extracts, including of a water-soluble fruit powder (FW), a fatsoluble fruit powder (FF), a supercritical extract of fruit by-product (BS), and a mixture of leaf and fruit (MIX), were investigated in vitro. A DPPH radical assay for antioxidant activity was performed for these fractions alongside assay to evaluate the total phenolic and flavonoid content (TPC and TFC). As expected, the MIX had the highest DPPH radical scavenging activity ($RC_{50}=10.27{\mu}g/m{\ell}$), and the TPC and TFC also were highest in MIX ($225.7mg{\cdot}GAE/g$, and $25.18mg{\cdot}QE/g$, respectively). Nitric oxide (NO) production in LPS-induced RAW264.7 cells was estimated and the results indicated an over 75% decrease of NO production in FF and MIX. In other assays, the highest elastase inhibitory activity was found in FW. Conclusions: These results revealed that H. rhamnoides extracts have a high potential for antioxidant, anti-inflammatory and antiwrinkle activities. H. rhamnoides products are suggested to be applied as the functional materials of cosmetic ingredients.

• Journal of the Korean Applied Science and Technology
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• v.34 no.2
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• pp.296-304
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• 2017

The purpose of this study was to investigate the applicability of the Psidium guajava leaf extract as a whitening functional cosmetic material. We measured DPPH radical scavenging activity, intracellular ROS, cytotoxicity in B16F10 melanoma cells and cytoprotective effect on ultraviolet A, in vitro tyrosinase inhibitory effect and melanin biosynthesis inhibitory effect. The antioxidative effect was confirmed through high DPPH radical scavenging activity and intracellular ROS activity inhibition measurement of the Psidium guajava leaf extract. The survival rate of B16F10 melanoma cells was more than 98% at all concentrations, and the cytoprotective effect from ultraviolet ray A was found to increase in a concentration-dependent manner. In addition, in vitro tyrosinase activity inhibitory effect of 10% and melanin biosynthesis inhibitory effect of 20% were observed. Through less toxicity for B16F10 melanoma cell, high antioxidant activity, inhibition of tyrosinase activity and melanin biosynthesis inhibitory effect, we confirmed the possibility of developing the Psidium guajava leaf extract as a whitening functional cosmetic material with a safe and excellent whitening effect.

• KSBB Journal
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• v.26 no.3
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• pp.260-265
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• 2011

This study aimed to examine the treatment effect of Muraenesox cinereus extract product combined with high frequency on men's damaged skin. The subjects were treated by a product containing M. cinereus extract combined with high frequency therapy for six weeks and tested in skin condition. First, for moisture level change, there was no significant difference between the control group treated only by high frequency therapy and the experimental group treated by a M. cinereus extract product combined with high frequency therapy. But the subjects who increased consistently in moisture level in the cheek and chin were more common in the experimental group. Second, for an oil level, prominently high increase was found in both the control group and the experimental group. Finally, for a rough level, while there was little difference in the control group between immediately after peeling and after six weeks, high improvement effect on a curve was found in the experimental group. Based on this result, cosmetics using M. cinereus extract may have a positive effect on men's skin which is exposed to several stress factors. Accordingly, this result will contribute to developing men's functional cosmetics.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.38 no.2
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• pp.163-169
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• 2012

In this study, silk-gland powder of silkworm was investigated for the usefulness as a potential agent for functional cosmetics, total content of amino acids and DPPH free radical scavenging assay, and clinical trial were done. The analysis of the amino acids of silk-gland powder showed that serine (26.77 %) content was the highest and aspartic acid, glycine, and glutamic acid followed that. DPPH free radical scavenging activity of silk-gland powder was lower than vitamin C (82.3 % v.s. 97 %), The moisture and elasticity were increased in silk-gland powder compared to control cosmetics by 257.2 % and 181.15 %, relatively. These results suggest that silk-gland powder of silkworm may have beneficial properties as a material for cosmeceuticals.