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http://dx.doi.org/10.12925/jkocs.2017.34.2.296

Antioxidant Activity and Whitening activity of Psidium guajava leaf extract  

You, Seon-hee (Department of Bioengineering, Konkuk University)
Publication Information
Journal of the Korean Applied Science and Technology / v.34, no.2, 2017 , pp. 296-304 More about this Journal
Abstract
The purpose of this study was to investigate the applicability of the Psidium guajava leaf extract as a whitening functional cosmetic material. We measured DPPH radical scavenging activity, intracellular ROS, cytotoxicity in B16F10 melanoma cells and cytoprotective effect on ultraviolet A, in vitro tyrosinase inhibitory effect and melanin biosynthesis inhibitory effect. The antioxidative effect was confirmed through high DPPH radical scavenging activity and intracellular ROS activity inhibition measurement of the Psidium guajava leaf extract. The survival rate of B16F10 melanoma cells was more than 98% at all concentrations, and the cytoprotective effect from ultraviolet ray A was found to increase in a concentration-dependent manner. In addition, in vitro tyrosinase activity inhibitory effect of 10% and melanin biosynthesis inhibitory effect of 20% were observed. Through less toxicity for B16F10 melanoma cell, high antioxidant activity, inhibition of tyrosinase activity and melanin biosynthesis inhibitory effect, we confirmed the possibility of developing the Psidium guajava leaf extract as a whitening functional cosmetic material with a safe and excellent whitening effect.
Keywords
Anti-oxidant; Melanin; Psidium guajava leaf; ROS; UV-A;
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Times Cited By KSCI : 11  (Citation Analysis)
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