• 제목/요약/키워드: Functional attribute

검색결과 96건 처리시간 0.026초

Proteomic Functional Characterization of Bovine Stromal Vascular Cells from Omental, Subcutaneous and Intramuscular Adipose Depots

  • Rajesh, Ramanna Valmiki;Kim, Seong-Kon;Park, Mi-Rim;Nam, Jin-Seon;Kim, Nam-Kuk;Kwon, Seulemina;Yoon, Du-Hak;Kim, Tae-Hun;Lee, Hyun-Jeong
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제24권1호
    • /
    • pp.110-124
    • /
    • 2011
  • Anatomically separate fat depots differ in size, function, and contribution to pathological states such as the metabolic syndrome. We isolated pre-adipocytes from different adipose depots, omental, subcutaneous and intramuscular, of beef cattle, and cultured in vitro to determine the basis for the variations and attribute these variations to the inherent properties of adipocyte progenitors. The proliferating cells from all depots before the confluence were harvested and the proteome was analyzed by a functional proteomic approach, involving 2-DE and MALDI-TOF/TOF. More than 252 protein spots were identified, selected and analyzed by Image Master (ver 7.0) and MALDI-TOF/TOF. Further, our analysis showed that there were specific differences in proteome expression patterns among proliferating precursor cells from the three depots. Sixteen proteins were found to be differentially expressed and these were identified as proteins involved in cellular processes, heat shock/chaperones, redox proteins, cytoskeletal proteins and metabolic enzymes. The results also enabled us to understand the basic roles of these proteins in different inherent properties exhibited by adipose tissue depots.

하천의 인공구조물이 저서성 대형무척추동물 군집에 미치는 영향 (The Influence of Artificial Structures on Benthic Macroinvertebrate Communities in Streams)

  • 김봉성;심광섭;김선희;권오창;서을원;이종은
    • 한국환경과학회지
    • /
    • 제22권3호
    • /
    • pp.309-318
    • /
    • 2013
  • This study was conducted for determining the influence of artificial structures on benthic macroinvertebrate communities in stream. Sampling was taken at upper(pool), down(riffle) and control(riffle) from two check dams, two weirs, one agricultural reservoir, and one multipurpose dam in northern part of Gyeongsangbuk-do. The benthic macroinvertebrate communities of these structures were surveyed during 2009 to 2011. The simple habitat of benthic macroinvertebrates occurred at the upper sites due to pooling effects from artificial structures. Specifically, Check dam1, Jusanji, Imha dam showed very low biological attribute values compared to the down and control sites, which have greater difference in substrate characteristics. However, in the upper sites of Check dam2, Weir1 and Weir2, the difference of values of biological attributes was relatively smaller. Also, proportion of functional feeding groups and functional habit groups were relatively simpler at upper stream and the degree of community differences was greater between upper and down, control sites. Spearman's correlation between biological attributes and substrate characteristics, water quality parameters had significant correlations; particularly, the substrate characteristics were more significantly related. In conclusion, the pool caused by artificial structures had negative effects on benthic macroinvertebrate communities thus leading to simplified stream habitats at upper stream ecosystems.

사용자 이벤트 기반의 정보구조 모델링을 이용한 비즈니스 업무 분석에서의 클래스 추출 방법 (User Event-based Information Structure Modeling for Class Abstraction of Business System)

  • 이혜선;박재년
    • 정보처리학회논문지D
    • /
    • 제12D권7호
    • /
    • pp.1071-1078
    • /
    • 2005
  • 비즈니스 시스템 분석을 위한 유스케이스 모델링은 유스케이스의 기능 별 분해 수준 및 시나리오의 구체적인 기술 단계를 어느 수준까지 작성해야 할 지 결정하기 어렵고 사용자가 분석 결과를 쉽게 이해하기가 어렵다. 본 논문에서는 비즈니스 시스템 분석 단계에서 사용자와 개발자 모두 쉽게 이해할 수 있는 표기법을 사용하여 사용자의 요구사항을 직관적으로 표현할 수 있는 정보구조 모델링을 정의하고, 객체 타입 별로 이벤트 객체, 재산 객체, 거래 객체로 분류 정의하여 추출하는 방법에 대해 제안함으로써 사용자의 요구사항 변경에 쉽게 대처하고, 개발자들이 분석 결과를 기반으로 설계를 위한 클래스 도출을 보다 용이하게 할 수 있도록 한다.

In silico genome wide identification and expression analysis of the WUSCHEL-related homeobox gene family in Medicago sativa

  • Yang, Tianhui;Gao, Ting;Wang, Chuang;Wang, Xiaochun;Chen, Caijin;Tian, Mei;Yang, Weidi
    • Genomics & Informatics
    • /
    • 제20권2호
    • /
    • pp.19.1-19.15
    • /
    • 2022
  • Alfalfa (Medicago sativa) is an important food and feed crop which rich in mineral sources. The WUSCHEL-related homeobox (WOX) gene family plays important roles in plant development and identification of putative gene families, their structure, and potential functions is a primary step for not only understanding the genetic mechanisms behind various biological process but also for genetic improvement. A variety of computational tools, including MAFFT, HMMER, hidden Markov models, Pfam, SMART, MEGA, ProtTest, BLASTn, and BRAD, among others, were used. We identified 34 MsWOX genes based on a systematic analysis of the alfalfa plant genome spread in eight chromosomes. This is an expansion of the gene family which we attribute to observed chromosomal duplications. Sequence alignment analysis revealed 61 conserved proteins containing a homeodomain. Phylogenetic study sung reveal five evolutionary clades with 15 motif distributions. Gene structure analysis reveals various exon, intron, and untranslated structures which are consistent in genes from similar clades. Functional analysis prediction of promoter regions reveals various transcription binding sites containing key growth, development, and stress-responsive transcription factor families such as MYB, ERF, AP2, and NAC which are spread across the genes. Most of the genes are predicted to be in the nucleus. Also, there are duplication events in some genes which explain the expansion of the family. The present research provides a clue on the potential roles of MsWOX family genes that will be useful for further understanding their functional roles in alfalfa plants.

공간분석(空間分析)모델링에 의한 산지(山地)의 토사붕괴방재기능(土砂崩壞防災機能) 적합도(適合度) 평가(評價) (Application of Spatial Analysis Modeling to Evaluating Functional Suitability of Forest Lands against Land Slide Hazards)

  • 정주상;김형호;차재민
    • 한국산림과학회지
    • /
    • 제90권4호
    • /
    • pp.535-542
    • /
    • 2001
  • 이 연구의 목적은 토사붕괴산지재해에 대한 산지의 기능적합도 평가를 위한 공간분석모델링기법을 개발하기 위해 수행되었다. 기능적합도는 산지의 토사붕괴 가능성에 따라 상, 중, 하의 3단계로 구분되었다. 토사붕괴의 가능성온 경사, 모암, 토심, 경사형태, 임상 및 임목의 직경급과 같은 7개의 입지인자들에 대한 측정치를 이용하여 추정되었고, 이 과정에 토사붕괴 발생 요인으로서 각 인자들의 상대적 가중치는 AHP기법에 의해 결정되었다. 공간분석모델링은 7개 입지인자들에 대한 $25m{\times}25m$ grid 분석 혹은 TIN 분석을 통해 기초 layer 작성에서 시작된다. 이를 토대로 재분류 및 점수화 과정을 거쳐 토사붕괴 가능성 추정에 필요한 인자들의 속성 값을 지니는 새로운 layer를 형성한다. 이러한 속성 값에 가중치를 적용하고 지도대수분석을 통해 $25m{\times}25m$ cell 단위의 기능평가도를 작성하고, 마지막으로 cell-grouping을 통해 보다 실무적인 기능도를 작성하게 된다. 이 논문은 이러한 일련의 공간분석모델링 과정을 방법론적 관점에서 제시한다.

  • PDF

MicroRNA Target Recognition: Insights from Transcriptome-Wide Non-Canonical Interactions

  • Seok, Heeyoung;Ham, Juyoung;Jang, Eun-Sook;Chi, Sung Wook
    • Molecules and Cells
    • /
    • 제39권5호
    • /
    • pp.375-381
    • /
    • 2016
  • MicroRNAs (miRNAs) are small non-coding RNAs (~22 nucleotides) regulating gene expression at the post-transcriptional level. By directing the RNA-induced silencing complex (RISC) to bind specific target mRNAs, miRNA can repress target genes and affect various biological phenotypes. Functional miRNA target recognition is known to majorly attribute specificity to consecutive pairing with seed region (position 2-8) of miRNA. Recent advances in a transcriptome-wide method of mapping miRNA binding sites (Ago HITS-CLIP) elucidated that a large portion of miRNA-target interactions in vivo are mediated not only through the canonical "seed sites" but also via non-canonical sites (~15-80%), setting the stage to expand and determine their properties. Here we focus on recent findings from transcriptome-wide non-canonical miRNA-target interactions, specifically regarding "nucleation bulges" and "seed-like motifs". We also discuss insights from Ago HITS-CLIP data alongside structural and biochemical studies, which highlight putative mechanisms of miRNA target recognition, and the biological significance of these non-canonical sites mediating marginal repression.

Sensor Network Implementation of using Embedded Web Sever

  • Lee Jeong Gi;Shin Myung Souk;Park Do Joon;Lee Cheol Seung;Kim Choong Woon;Lee Joon
    • 대한전자공학회:학술대회논문집
    • /
    • 대한전자공학회 2004년도 학술대회지
    • /
    • pp.532-535
    • /
    • 2004
  • Architecture generation is the first step in the design of software systems. Most of the qualities that the final software system possesses are usually decided at the architecture development stage itself. Thus, if the final system should be usable, testable, secure, high performance, mobile and adaptable, then these qualities or non­functional requirements should be engineered into the architecture itself. In particular, adaptability is emerging as an important attribute required by almost all software systems. The machinery and tools in the remote site surveillance and connects intelligence information machinery and tools at Internet. We need the server which uses different embedded operating system to become private use. With the progress of information-oriented society, many device with advanced technologies invented by many companies. However, the current firmware technologies have many problems to meet such high level of new technologies. In this paper, we have successfully ported linux on an embedded system, which is based on intel StrongARM SA-1 1 10 processor, then written several network modules for internet-based network devices.

  • PDF

공간구성에 있어서 유기적 형태의 응용 가능성에 관한 연구 (A Study on applied possibility of Organic Form In Architectural space-Design)

  • 김성혜
    • 한국실내디자인학회논문집
    • /
    • 제14호
    • /
    • pp.10-18
    • /
    • 1998
  • This study aims to make clear visual quality of organic form and structural order that is immanent in nature about a form as formative principles of architectural space design the significanced of this study is to prove the application possibility in to functional form architectural space design. All organic forms in nature has a unique shape and pattern in structure to be self-controled and good in order. Such an order in nature comes from regular construction and ratio principles which has aesthetical order by mathmetics. The specialty of beauty in nature can be revealed not only visual form but also the ratio balance and rhythm of structural principles. As we examine the aesthetic source embodied some object can be developed in to basic principles. Furthermore through this study we can find out that the form construction theory in nature forms share the quality attribute with geometrical form to be shown in architectural space design. Natural forms are ultimate visual expression of power that effects on the architectural space design. The rule of power in nature as nature formal characteristics have a direct influence and can be also applied to architectural construction. Therefore I expect that this study will be linked and continued to another structural view.

  • PDF

환경정보의 체계적 분석 및 관리방안 연구 (Studies on Systematic Analysis and Management of Environmental Information)

  • 김명진;장준기;이재운;권명희;강인구;서창완
    • 환경영향평가
    • /
    • 제3권1호
    • /
    • pp.1-8
    • /
    • 1994
  • For managing and analyzing effectively diverse and complicated environmental informations, informations should be built systematically, and techniques should be developed. Environmental Information System(EIS) is composed of environmental informations, GIS, and manpower. Recently it is applied to Environmental Impact Assessment and environmental management, etc.. For effective application, EIS techniques will be improved. This article has four components. First, it describes building of environmental information comprising geographic and attribute data using GIS in Chuncheon district. Second, it explains programming for effective information analysis and management using AML(Are Macro Language in ARC INFO). Third, it provides specific functional capabilities including suitability analysis. Based on these analysis, this study makes some examples for systematic analysis and management of environmental information using interactive system.

  • PDF

거주자의 성격유형별 가구배치의 선호특성에 관한 연구 (A Study on Residential Furniture Layout Preference Characteristics with the Personal Types)

  • 김남효;서정연;이상호
    • 한국실내디자인학회논문집
    • /
    • 제14권6호
    • /
    • pp.244-251
    • /
    • 2005
  • With the development of cognitive science and environmental psychology, there have been growing researches and discussions on the relationship between the residential design preferences and personality types. MBTI personality types have been earning popular credibility. MBTI means Myers-Briggs Type Indicator. It is based on Carl Jung's theory of psychological type. This study is based on Myers-Briggs theory to explain residential furnishing preference and explores the relationship between the four bi-polar personality types-Extroversion/Introversion, Sensing/Intuition, Thinking/Perceiving and residential furnishing preference. These tests were conducted to two hundred and twelve adult residents who live in Seoul, Korea. These tests were analyzed several significances by Chi-Square with SPSS for windows software. (E) Extroverted residents prefer layouts for interaction with guests. (I) Introverted residents prefer centripetal layout around the bed. (S) Sensing residents prefer practical and functional layouts. (N) Intuitive residents prefer personal and conceiving layouts. (T) Thinking residents prefer for attribute of space. (F) Feeling residents for familiar conversation. (J) Judging residents prefer systematic and complete layouts. (P) Perceiving residents prefer adaptable and flexible layouts. In conclusion, personality types can have a determining role in preference of residential furnishing layouts. This study suggests that residential designers should take into account clients' personality types prefer effective designing and should provide a variety of alternatives reflecting clients' preferences. This will promote clients' pleasantness and satisfaction in dwelling at home.