• Preventive Nutrition and Food Science
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• v.19 no.2
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• pp.69-74
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• 2014

The present study investigated the anti-obesity effects of Mycoleptodonoides aitchisonii (MA) in mice fed a high-fat (HF) diet. Two groups were fed either a normal control diet or an HF (45% kcal fat) diet for 12 weeks and three groups were fed an HF diet supplemented with powdered MA (MAP, 1%, 3%, and 5%) for 12 weeks. The anti-obesity effects of MAP supplementation on body weight, fat mass development, and lipid-related markers were assessed. Consumption of an HF diet resulted in increased body weight, serum lipids, relative adipose tissues weight, and liver fat accumulation. However, administration of MAP significantly decreased body weight gain, food intake, food efficiency ratio, hepatic cholesterol level, and adipose tissue weight in a dose-dependent manner. In addition, treatment with MAP significantly reduced the occurrence of fatty liver deposits and steatosis, and inhibited an HF diet-induced increase in adipocyte size. These results suggest that dietary supplementation with MAP exerts anti-obesity effects and indicate that MAP could be used as a functional food to control obesity.

• Journal of Korea Multimedia Society
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• v.8 no.8
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• pp.1023-1031
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• 2005

LBS(Location Based Service) and GIS (Geographic Information System) are supporting necessary services for system which provides geographic information using location information based on various platforms. However the mobile computing environments such as PDA system have serious limitations in functional viewpoints compare of general computing environments, it has problems for developing GIS system which is providing various information. In this paper, we suggest the reduced methods of digital map and format of web-linked digital mao in order to fit in mobile environment. As a result of map generation, the total capacity of the supported digital map was diminished about $99.34\%$ than the original map.

• Toxicological Research
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• v.26 no.1
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• pp.37-46
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• 2010

This study aimed to elucidate anti-inflammatory activities from extracts of Asterina pectinifera on nitric oxide (NO) production, TNF-${\alpha}$ and IL-6 release in lipopolysaccharide (LPS)-stimulated murine macrophage cell, RAW264.7. We prepared the methanolic extracts (60-MAP, 70-MAP, 80-MAP and 90-MAP), aqueous extract (W-AP) and functional bioactive compound fraction (He-AP and EA-AP) from Asterina pectinifera according to extract method. The 60-MAP, 70-MAP, 80-MAP, 90-MAP and W-AP were significantly suppressed LPS-induced production NO, TNF-${\alpha}$ and IL-6 secretion in a concentration-dependent manner (P < 0.05). Especially, 80-MAP by extracted 80% methanol had the strongest activity in reduction of inflammatory mediators among these extracts. Indeed, to identify active fraction, which contained potential bioactive compounds, from 80-MAP of Asterina pectinifera, we tested anti-inflammatory activity of the He-AP or the EA-AP. The He-AP was next extracted from 80-MAP and the EA-AP were extracted from the other methanol layer except the He-AP. The EA-AP demonstrated a strong anti-inflammatory effect through its ability to reduce NO production and it also inhibited the production of proinflammatory cytokines such as IL-6 and TNF-${\alpha}$ at low concentration. These results suggested that the methanolic extract from Asterina pectinifera had the potential inhibitory effects on the production of these inflammatory mediators.

• Bulletin of the Korean Mathematical Society
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• v.40 no.4
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• pp.565-576
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• 2003

In this paper, we determine the general solution of the quartic equation f(x+2y)+f(x-2y)+6f(x) = 4[f(x+y)+f(x-y)+6f(y)] for all x, $y\;\in\;\mathbb{R}$ without assuming any regularity conditions on the unknown function f. The method used for solving this quartic functional equation is elementary but exploits an important result due to M. Hosszu [3]. The solution of this functional equation is also determined in certain commutative groups using two important results due to L. Szekelyhidi [5].

• Kyungpook Mathematical Journal
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• v.49 no.4
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• pp.691-700
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• 2009

We use the fixed alternative theorem to establish Hyers-Ulam-Rassias stability of the quadratic functional equation where functions map a linear space into a complete quasi p-normed space. Moreover, we will show that the continuity behavior of an approximately quadratic mapping, which is controlled by a suitable continuous function, implies the continuity of a unique quadratic function, which is a good approximation to the mapping. We also give a few applications of our results in some special cases.

• Journal of the Chungcheong Mathematical Society
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• v.24 no.2
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• pp.239-245
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• 2011

In this paper, we will study the tension field of the function related to a Riemannain submersion ${\pi}\;:\;N{\rightarrow}M$ with totally geodesic fibres. In case that the Riemannain submersion ${\pi}\;:\;N{\rightarrow}M$ particularly has a smooth map $f\;:\;M{\rightarrow}N$ which happens to be a section, we will show that tension field ${\tau}(f)$ of the energy functional can be decomposed into the horizontal and vertical parts.

• Molecules and Cells
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• v.40 no.3
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• pp.230-242
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• 2017

In the Arabidopsis genome, approximately 80 MAP3Ks (mitogen-activated protein kinase kinase kinases) have been identified. However, only a few of them have been characterized, and the functions of most MAP3Ks are largely unknown. In this paper, we report the function of MAP3K16 and several other MAP3Ks, MAP3K14/15/17/18, whose expression is salt-inducible. We prepared MAP3K16 overexpression (OX) lines and analyzed their phenotypes. The result showed that the transgenic plants were ABA-insensitive during seed germination and cotyledon greening stage but their root growth was ABA-hypersensitive. The OX lines were more susceptible to water-deficit condition at later growth stage in soil. A MAP3K16 knockout (KO) line, on the other hand, exhibited opposite phenotypes. In similar transgenic analyses, we found that MAP3K14/15/17/18 OX and KO lines displayed similar phenotypes to those of MA3K16, suggesting the functional redundancy among them. MAP3K16 possesses in vitro kinase activity, and we carried out two-hybrid analyses to identify MAP3K16 substrates. Our results indicate that MAP3K16 interacts with MKK3 and the negative regulator of ABA response, ABR1, in yeast. Furthermore, MAP3K16 recombinant protein could phosphorylate MKK3 and ABR1, suggesting that they might be MAP3K16 substrates. Collectively, our results demonstrate that MAP3K16 and MAP3K14/15/17/18 are involved in ABA response, playing negative or positive roles depending on developmental stage and that MAP3K16 may function via MKK3 and ABR1.

• Bulletin of the Korean Mathematical Society
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• v.42 no.4
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• pp.757-776
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• 2005

In this paper we establish the stability of a Jensen type functional equation, namely f(xy) - f($xy^{-1}$) = 2f(y), on some classes of groups. We prove that any group A can be embedded into some group G such that the Jensen type functional equation is stable on G. We also prove that the Jensen type functional equation is stable on any metabelian group, GL(n, $\mathbb{C}$), SL(n, $\mathbb{C}$), and T(n, $\mathbb{C}$).

• Clinical and Experimental Reproductive Medicine
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• v.29 no.2
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• pp.117-127
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• 2002

Objective: This study was to investigate the generation of the functional neuron derived from human embryonic stem (hES, MB03) cells on in vitro neural cell differentiation system. Methods: For neural progenitor cell formation derived from hES cells, we produced embryoid bodies (EB: for 5 days, without mitogen) from hES cells and then neurospheres (for $7{\sim}10$ days, 20 ng/ml of bFGF added N2 medium) from EB. And then finally for the differentiation into mature neuron, neural progenitor cells were cultured in i) N2 medium only (without bFGF), ii) N2 supplemented with 20 ng/ml platelet derived growth factor-bb (PDGF-bb) or iii) N2 supplemented with 5 ng/ml brain derived neurotrophic factor (BDNF) for 2 weeks. Identification of neural cell differentiation was carried out by immunocytochemistry using $\beta_{III}$-tubulin (1:250), MAP-2 (1:100) and GFAP (1:500). Also, generation of functional neuron was identified using anti-glutamate (Sigma, 1:1000), anti-GABA (Sigma, 1:1000), anti-serotonin (Sigma, 1:1000) and anti-tyrosine hydroxylase (Sigma, 1:1000). Results: In vitro neural cell differentiation, neurotrophic factors (PDGF and BDNF) treated cell groups were high expressed MAP-2 and GFAP than non-treated cell group. The highest expression pattern of MAP-2 and $\beta_{III}$-tubulin was indicated in BDNF treated group. Also, in the presence of PDGF-bb or BDNF, most of the neural cells derived from hES cells were differentiated into glutamate and GABA neuron in vitro. Furthermore, we confirmed that there were a few serotonin and tyrosine hydroxylase positive neuron in the same culture environment. Conclusion: This results suggested that the generation of functional neuron derived from hES cells was increased by addition of neurotrophic factors such as PDGF-bb or BDNF in b-FGF induced neural cell differentiation system and especially glutamate and GABA neurons were mainly produced in the system.

• Journal of the Korea Society of Computer and Information
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• v.21 no.9
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• pp.51-55
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• 2016

High-capacity, high quality services should be guaranteed in mobile communication environment. Excellent channel coding and compensation techniques are required so as to improve data reliability on fading channels. In this paper, we propose a method using double pilots, estimates and compensates for the fading of information symbols. The proposed method using Log-MAP Turbo decoder through the iterative decoder, improves BER performance under the environment of the frequency selective fading channel. Compared to the existing methods, the suggested methods show functional improvement of approximately 3dB in case that the number of iteration decoding is 5 and BER is $10^{-4}$.