• 제목/요약/키워드: Functional Change

검색결과 1,916건 처리시간 0.034초

Molecular Structure and Vibrational Spectra of Biphenyl in the Ground and the Lowest Triplet States. Density Functional Theory Study

  • 이상연
    • Bulletin of the Korean Chemical Society
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    • 제19권1호
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    • pp.93-98
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    • 1998
  • The molecular geometries and harmonic vibrational frequencies of biphenyl in the ground and the first excited triplet states have been calculated using the Hartree-Fock and Becke-3-Lee-Yang-Parr (B3LYP) density functional methods with 6-31G* basis set. Structural change occurs from a twisted benzene-like to a planar quinone-like form upon the excitation to the first excited state. Scaled harmonic vibrational frequencies for the ground state obtained from the B3LYP calculation show good agreement with the available experimental data. A few vibrational fundamentals for both states are newly assigned based on the B3LYP results.

피록시캄 겔의 음파영동이 원심성 운동-유발 근 손상의 기능회복에 미치는 효과 (Effects on Functional Recovery of Eccentric Exercise-Induced Muscle Damage by Phonophoresis of Piroxicam Gel)

  • 최석주;김태열;송명수;김영일;문성기
    • 대한임상전기생리학회지
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    • 제1권1호
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    • pp.17-29
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    • 2003
  • This study was investigated the effects on functional recovery of eccentric exercise-induced muscle damage by phonophoresis transdermal permeation of piroxicam gel and observed the change of amplitude at muscle action potential. Through eccentric exercise-induced muscle damage, performed healthy men and women take eccentric resistance exercise and measured action, potentials. The subjects were divided into three groups of four men each 24 hour, 48 hour, 72 hour. The results of this were as follows: 1. Change of maximal action potential at maximal voluntary contraction : The phonophoresis group was increase more than control group and gel group. 2. Change of average action potential at maximal voluntary contraction : The gel group was increase more than control group and phonophoresis group. 3. Change of maximal action potential at pain subthreshold voluntary contraction : The phonophoresis group was increase more significantly than control group and gel group. 4. Change of average action potential at pain subthreshold voluntary contraction : The phonophoresis group was increase more significantly than control group and gel group. In conclusion, the change of muscle action potential amplitude by eccentric exercise-induced muscle damage showed that the phonophoresis by pulsed ultrasound of piroxicam gel was improved the recovery of muscle function.

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Evaluation of the Functional and Non-functional Seat Sponge Effect in Sitting Chairs

  • Min, Seung Nam;Park, Se Jin;Subramaniyam, Murali;Lee, Heeran
    • 대한인간공학회지
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    • 제33권4호
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    • pp.255-265
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    • 2014
  • Objective: The purpose of this study was to evaluate comfort levels of functional and non-functional chairs using subjective comfort rating, interface pressure measurement, muscle activity measurement, and skin temperature measurement. Background: Chairs are used for a prolonged period of time for sitting in many places such as the office, at university, at school, in industry, and so on. Almost all people use chairs in their everyday life. The functional properties of the chair are associated with comfort. Method: The subjective evaluation contains questions regarding chair comfort which can be rated with five point scale. The body-seat interface pressure was measured using a pressure mat system. The symmetry of sitting was measured using electromyography. The change in body part (thigh and buttock) temperature before and after sitting on a chair was measured with an infrared camera. Results: Participants rated significantly (p < 0.05) higher comfort scores for the functional chair in relation to the buttock and thigh region. Also, the participants felt a better cushion effect in the functional chair. When using the functional chair, lower interface pressure, better thermal comfort, and better symmetry of erector spinae muscle activity were observed. Conclusion: Overall, interface pressure measurement, muscle activity measurement, thermal imaging and subjective comfort score results showed that the functional chair was more comfortable than the non-functional chair. Application: The adopted methodologies could be used to measure the seating comfort of train seats.

수면 분석을 위한 다중 모달 생체신호 측정 시스템 (Multimodal Bio-signal Measurement System for Sleep Analysis)

  • 김상규;유선국
    • 한국멀티미디어학회논문지
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    • 제21권5호
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    • pp.609-616
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    • 2018
  • In this paper, we designed a multimodal bio-signal measurement system to observe changes in the brain nervous system and vascular system during sleep. Changes in the nervous system and the cerebral blood flow system in the brain during sleep induce a unique correlation between the changes in the nervous system and the blood flow system. Therefore, it is necessary to simultaneously observe changes in the brain nervous system and changes in the blood flow system to observe the sleep state. To measure the change of the nervous system, EEG, EOG and EMG signal used for the sleep stage analysis were designed. We designed a system for measuring cerebral blood flow changes using functional near-infrared spectroscopy. Among the various imaging methods to measure blood flow and metabolism, it is easy to measure simultaneously with EEG signal and it can be easily designed for miniaturization of equipment. The sleep stage was analyzed by the measured data, and the change of the cerebral blood flow was confirmed by the change of the sleep stage.

시간축 서브밴드 해석을 이용한 적응적 움직임 추정에 관한 연구 (An adaptive motion estimation based on the temporal subband analysis)

  • 임중곤;정재호
    • 한국통신학회논문지
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    • 제21권6호
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    • pp.1361-1369
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    • 1996
  • Motion estimation is one of the key components for high quality video coding. In this paper, a new motion estimation scheme for MPEG-like video coder is suggested. The proposed temporally adaptive motion estimation scheme consists of five functional blocks: Temporal subband analysis (TSBA), extraction of temporal information, scene change detection (SCD), picture type replacement (PTR), and temporally adapted block matching algorithm (TABMA). Here all the functional components are based on the temporal subband analysis. In this papre, we applied the analysis part of subband decompostion to the temporal axis of moving picture sequence, newly defined the temporal activity distribution (TAD) and average TAD, and proposed the temporally adapted block matching algorithm, the scene change detection algorithm and picture type replacement algorithm which employed the results of the temporal subband analysis. A new block matching algorithm TABMA is capable of controlling the block matching area. According to the temporal activity distribution of objects, it allocates the search areas nonuniformly. The proposed SCD and PTR can prevent unavailable motion prediction for abrupt scene changes. Computer simulation results show that the proposed motion estimation scheme improve the quality of reconstructed sequence and reduces the number of block matching trials to 40% of the numbers of trials in conventional methods. The TSBA based scene change detection algorithm can detect the abruptly changed scenes in the intentionally combined sequence of this experiment without additional computations.

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경추 증후군 환자에서 상부경추변위에 대한 임상적 고찰 (Clinical study on deviation of upper cervical of patients with cervical syndrome)

  • 조명제;김동일;박쾌환
    • Journal of Acupuncture Research
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    • 제17권3호
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    • pp.188-198
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    • 2000
  • Objectives : We perform this study for help to recovery of cervical syndrome by analyzing structural deviation and cervical curvature in upper cervical vertebrae and definiting functional change through cervical body heat change in cevical lesion which is estimated by DITI. Methods : From sep. 1st. 1998 to aug, 31th. 1999, I make an experiment with the 102 OPD patients of this hospital vertebral-joint center, which were judged as a cervical syndrome and confirmed in upper cervical deviation by motion palpation and then were taken cervical simple X-ray and cervical thermograpy. Results : In the classfication of upper cervical deviation, AS deviation took 98% and abnormal cervical curvature took 68%. in the Chief complain neck-shoulder pain took 78%. In the results of DITI, average value of all objects show $032{\pm}0.18$ as a meaning result. Conclusions : In medical treatment of cervical syndrome, this result shows necessity of keeping pace with remedy of upper cervical deviation and medical treatment of functional change and We can learn necessity of detailed assessment through continual clinical examination.

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한국형 기후변화대응 분석모형의 경제적 가치 (Economic Valuation of the Korean Climate Change Mitigation and Adaptation Model)

  • 최이중;이미숙
    • 한국대기환경학회지
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    • 제30권3호
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    • pp.270-280
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    • 2014
  • The objective of this research is to quantitatively valuate the economic value of analysis model related to climate change mitigation and adaptation. Due to the fact that the subject of this research, which is the Korean climate change mitigation and adaptation model, has not been actualized, a conjoint analysis applying stated preference data has utilized. As results, among the many attributes considered in this research, the value of the attribute related to reflecting Korea's current situation is analyzed to be largest in both greenhouse gas (GHG) mitigation model and climate change adaptation model. Additionally, if all the considered functional aspects are assumed to be feasible, the economic value of the Korean GHG mitigation model is assumed to be 60.3 billion Korean won(KRW) and the Korean climate change adaptation model is assumed to be 51 billion KRW.

The Effect of Action Observation Training on Balance and Cognition on the Elderly with Dementia

  • Cheol-Jin Kang;Sung-Min Son;Se-Hee Park
    • The Journal of Korean Physical Therapy
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    • 제36권2호
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    • pp.61-66
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    • 2024
  • Purpose: The purpose of this study was to investigate the impact of action observation training (AOT) on the balance and cognition of the elderly with dementia. Methods: Twenty-four participants were randomly assigned to experimental and control groups (12 participants each). The 5-week intervention involved 45 minutes sessions, three times a week. Both groups did 30 minutes of general physical exercises, followed by the experimental group watching a 5 minutes video featuring functional movements and imitating them for 10 minutes. The control group watched a scenic video and did functional training for 10 minutes, mimicking the experimental group. All participants were evaluated using the Timed Up and Go (TUG) test, Functional Reaching Test (FRT), Berg's Balance Scale (BBS), and Korean version of Mini-Mental State Examination (K-MMSE) before and after the intervention. A paired t-test was conducted to compare the within-group change before and after the intervention. Two-way repeated measures ANOVA was performed to compare the between-group difference. The statistical significance level was set to p=0.05 for all variables. Results: The experimental group showed significant within-group changes in the TUG test, FRT, BBS, and K-MMSE (p<0.05). The control group showed a significant change in FRT and K-MMSE (p<0.05). A significant difference was observed between the experimental group and the control group regarding the change in the TUG test, BBS, and K-MMSE after the interventions (p<0.05). Conclusion: The findings of this study suggest that the AOT and repetition of actual movements, led to more significant improvements in balance and cognitive abilities compared to the control group that observed scenic landscapes.

Functional Implications of Transporters Under Nitrosative Stress Conditions

  • Yu, Kyung-Ha;Maeng, Han-Joo;Chung, Suk-Jae
    • Journal of Pharmaceutical Investigation
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    • 제40권3호
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    • pp.139-153
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    • 2010
  • Nitrosative stress is defined as pathophysiological conditions that are related to covalent modifications of proteins by nitration/nitrosylation by forms of nitrogen oxide ($NO_x$), leading to DNA damage, ultimately, cell death. This type of stress condition appears to be associated with a number of disease states, including diabetes, inflammation and neurodegenerative diseases. Since these pathological conditions are frequently chronic in nature and, thus, require long-term treatment, changes in pharmacokinetics are likely to affect the therapy. Transporters are membrane proteins that facilitate the movement of substrates, including drugs, across plasma membranes of epithelial / endothelial cells. Since it is now increasingly evident that transporters are pharmacokinetically significant, functional alteration of transporters by this stress condition may have therapeutic relevance. In this review, experimental techniques that are used to study both in vivo and in vitro nitrosative stress are summarized and discussed, along with available literature information on the functional implication of transporters under conditions of nitrosative stress conditions. In the literature, both functional induction and impa irment were apparently present for both drug transporter families [i.e., ATP-binding cassette (ABC) and solute carrier families (SLC)]. Furthermore, a change in the function of a certain transporter appears to have temporal dependency by impairment in the early phase of nitrosative stress and induction thereafter, suggesting that the role of nitrosative stress is complex in terms of functional implications of the transporters. Although the underlying mechanisms for these alterations are not fully understood, protein nitration/nitrosylation appears to be involved in the functional impairment whereas transcript factor(s) activated by nitrosative stress may play a role, at least in part, in functional induction. Interestingly, functional induction under conditions of nitrosative stress has not been observed for SLC transporters while such impairment has been documented for both ABC and SLC transporters. Further investigations appear to be necessary to fully delineate the underlying reasons for these differences on the impact and importance of nitrosative stress conditions.

Effects of a Postpartum Back Pain Relief Program for Korean Women

  • Oh, Hyun-Ei;Lee, Young-Sook;Shim, Mi-Jung;Kim, Jin-Sun
    • 대한간호학회지
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    • 제37권2호
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    • pp.163-170
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    • 2007
  • Purpose. Despite the high prevalence of back pain and its subsequent effects in post-partum women, intervention programs are scarce. The purpose of this study was to test the effects of a back-pain-reducing program on post-partum women who experienced low-back pain during pregnancy. Methods. A non-equivalent control-group pretest-posttest design was used. Pregnant women who attended a hospital for prenatal check-ups and experienced back pain participated in an intervention program (n=27), and the results were compared with women in a control group from another hospital (n=25). Results. At 8 weeks post-partum, the pain intensity, functional limitations were lower in the intervention group than in the control group. However, differences in mean change of the pain intensity and functional limitations between 36 and 39 weeks of gestation and at 8 weeks post-partum were not statistically significant between the groups. Moreover, the flexibility, post-partum functional status, and post-partum depression did not differ significantly between the groups. Conclusions. A back-pain-relief program in this study was not effective to reduce the back-pain intensity in post-partum women and to decrease the associated functional limitations. The implications for nursing practice and directions for future research are discussed.