• Title/Summary/Keyword: Functional Attribute

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Proteomic Functional Characterization of Bovine Stromal Vascular Cells from Omental, Subcutaneous and Intramuscular Adipose Depots

  • Rajesh, Ramanna Valmiki;Kim, Seong-Kon;Park, Mi-Rim;Nam, Jin-Seon;Kim, Nam-Kuk;Kwon, Seulemina;Yoon, Du-Hak;Kim, Tae-Hun;Lee, Hyun-Jeong
    • Asian-Australasian Journal of Animal Sciences
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    • v.24 no.1
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    • pp.110-124
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    • 2011
  • Anatomically separate fat depots differ in size, function, and contribution to pathological states such as the metabolic syndrome. We isolated pre-adipocytes from different adipose depots, omental, subcutaneous and intramuscular, of beef cattle, and cultured in vitro to determine the basis for the variations and attribute these variations to the inherent properties of adipocyte progenitors. The proliferating cells from all depots before the confluence were harvested and the proteome was analyzed by a functional proteomic approach, involving 2-DE and MALDI-TOF/TOF. More than 252 protein spots were identified, selected and analyzed by Image Master (ver 7.0) and MALDI-TOF/TOF. Further, our analysis showed that there were specific differences in proteome expression patterns among proliferating precursor cells from the three depots. Sixteen proteins were found to be differentially expressed and these were identified as proteins involved in cellular processes, heat shock/chaperones, redox proteins, cytoskeletal proteins and metabolic enzymes. The results also enabled us to understand the basic roles of these proteins in different inherent properties exhibited by adipose tissue depots.

The Influence of Artificial Structures on Benthic Macroinvertebrate Communities in Streams (하천의 인공구조물이 저서성 대형무척추동물 군집에 미치는 영향)

  • Kim, Bong Sung;Sim, Kwang Sub;Kim, Sun Hee;Kwon, O Chang;Seo, Eul Won;Lee, Jong Eun
    • Journal of Environmental Science International
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    • v.22 no.3
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    • pp.309-318
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    • 2013
  • This study was conducted for determining the influence of artificial structures on benthic macroinvertebrate communities in stream. Sampling was taken at upper(pool), down(riffle) and control(riffle) from two check dams, two weirs, one agricultural reservoir, and one multipurpose dam in northern part of Gyeongsangbuk-do. The benthic macroinvertebrate communities of these structures were surveyed during 2009 to 2011. The simple habitat of benthic macroinvertebrates occurred at the upper sites due to pooling effects from artificial structures. Specifically, Check dam1, Jusanji, Imha dam showed very low biological attribute values compared to the down and control sites, which have greater difference in substrate characteristics. However, in the upper sites of Check dam2, Weir1 and Weir2, the difference of values of biological attributes was relatively smaller. Also, proportion of functional feeding groups and functional habit groups were relatively simpler at upper stream and the degree of community differences was greater between upper and down, control sites. Spearman's correlation between biological attributes and substrate characteristics, water quality parameters had significant correlations; particularly, the substrate characteristics were more significantly related. In conclusion, the pool caused by artificial structures had negative effects on benthic macroinvertebrate communities thus leading to simplified stream habitats at upper stream ecosystems.

User Event-based Information Structure Modeling for Class Abstraction of Business System (사용자 이벤트 기반의 정보구조 모델링을 이용한 비즈니스 업무 분석에서의 클래스 추출 방법)

  • Lee Hye-Seon;Park Jai-Nyun
    • The KIPS Transactions:PartD
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    • v.12D no.7 s.103
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    • pp.1071-1078
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    • 2005
  • Use case modeling is a widely used technique for functional requirements analysis of business system but it is difficult to identify a use cases at the right level and use case specifications are too long and confusing. It is also hard to determine a functional decomposition Phases·s of use cases. Therefore customer doesn't understand the use cases. This paper is defining concept of the Information Structure Modeling(ISM) and analyzing business system for the customer's perspective. ISM is an efficient mechanism for analyzing user requirements and for Identifying objects in a business system using Attribute Structure Diagram which is a major tool of the ISM that describes user event. This paper is also to show how the classes are classified and derived as event-asset-transaction type in ISM. It provides a user-friendly approach to visually representing business model.

In silico genome wide identification and expression analysis of the WUSCHEL-related homeobox gene family in Medicago sativa

  • Yang, Tianhui;Gao, Ting;Wang, Chuang;Wang, Xiaochun;Chen, Caijin;Tian, Mei;Yang, Weidi
    • Genomics & Informatics
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    • v.20 no.2
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    • pp.19.1-19.15
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    • 2022
  • Alfalfa (Medicago sativa) is an important food and feed crop which rich in mineral sources. The WUSCHEL-related homeobox (WOX) gene family plays important roles in plant development and identification of putative gene families, their structure, and potential functions is a primary step for not only understanding the genetic mechanisms behind various biological process but also for genetic improvement. A variety of computational tools, including MAFFT, HMMER, hidden Markov models, Pfam, SMART, MEGA, ProtTest, BLASTn, and BRAD, among others, were used. We identified 34 MsWOX genes based on a systematic analysis of the alfalfa plant genome spread in eight chromosomes. This is an expansion of the gene family which we attribute to observed chromosomal duplications. Sequence alignment analysis revealed 61 conserved proteins containing a homeodomain. Phylogenetic study sung reveal five evolutionary clades with 15 motif distributions. Gene structure analysis reveals various exon, intron, and untranslated structures which are consistent in genes from similar clades. Functional analysis prediction of promoter regions reveals various transcription binding sites containing key growth, development, and stress-responsive transcription factor families such as MYB, ERF, AP2, and NAC which are spread across the genes. Most of the genes are predicted to be in the nucleus. Also, there are duplication events in some genes which explain the expansion of the family. The present research provides a clue on the potential roles of MsWOX family genes that will be useful for further understanding their functional roles in alfalfa plants.

Application of Spatial Analysis Modeling to Evaluating Functional Suitability of Forest Lands against Land Slide Hazards (공간분석(空間分析)모델링에 의한 산지(山地)의 토사붕괴방재기능(土砂崩壞防災機能) 적합도(適合度) 평가(評價))

  • Chung, Joosang;Kim, Hyungho;Cha, Jaemin
    • Journal of Korean Society of Forest Science
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    • v.90 no.4
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    • pp.535-542
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    • 2001
  • The objective of this study is to develop a spatial analysis modeling technique to evaluate the functional suitability of forest lands for land slide prevention. The functional suitability is classified into 3 categories of high, medium and low according to the potential of land slide on forest lands. The potential of land slide hazards is estimated using the measurements of 7 major site factors : slope, bed rock, soil depth, shape of slope, forest type and D.B.H. class of trees. The analytic hierarchical process is applied to determining the relative weight of site factors in estimating the potential of land slides. The spatial analysis modeling starts building base layers for the 7 major site factors by $25m{\times}25m$ grid analysis or TIN analysis, reclassifies them and produces new layers containing standardized attribute values, needed in estimating land slide potential. To these attributes, applied is the weight for the corresponding site factor to build the suitability classification map by map algebra analysis. Then, finally, cell-grouping operations convert the suitability classification map to the land unit function map. The whole procedures of the spatial analysis modeling are presented in this paper.

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MicroRNA Target Recognition: Insights from Transcriptome-Wide Non-Canonical Interactions

  • Seok, Heeyoung;Ham, Juyoung;Jang, Eun-Sook;Chi, Sung Wook
    • Molecules and Cells
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    • v.39 no.5
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    • pp.375-381
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    • 2016
  • MicroRNAs (miRNAs) are small non-coding RNAs (~22 nucleotides) regulating gene expression at the post-transcriptional level. By directing the RNA-induced silencing complex (RISC) to bind specific target mRNAs, miRNA can repress target genes and affect various biological phenotypes. Functional miRNA target recognition is known to majorly attribute specificity to consecutive pairing with seed region (position 2-8) of miRNA. Recent advances in a transcriptome-wide method of mapping miRNA binding sites (Ago HITS-CLIP) elucidated that a large portion of miRNA-target interactions in vivo are mediated not only through the canonical "seed sites" but also via non-canonical sites (~15-80%), setting the stage to expand and determine their properties. Here we focus on recent findings from transcriptome-wide non-canonical miRNA-target interactions, specifically regarding "nucleation bulges" and "seed-like motifs". We also discuss insights from Ago HITS-CLIP data alongside structural and biochemical studies, which highlight putative mechanisms of miRNA target recognition, and the biological significance of these non-canonical sites mediating marginal repression.

Sensor Network Implementation of using Embedded Web Sever

  • Lee Jeong Gi;Shin Myung Souk;Park Do Joon;Lee Cheol Seung;Kim Choong Woon;Lee Joon
    • Proceedings of the IEEK Conference
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    • 2004.08c
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    • pp.532-535
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    • 2004
  • Architecture generation is the first step in the design of software systems. Most of the qualities that the final software system possesses are usually decided at the architecture development stage itself. Thus, if the final system should be usable, testable, secure, high performance, mobile and adaptable, then these qualities or non­functional requirements should be engineered into the architecture itself. In particular, adaptability is emerging as an important attribute required by almost all software systems. The machinery and tools in the remote site surveillance and connects intelligence information machinery and tools at Internet. We need the server which uses different embedded operating system to become private use. With the progress of information-oriented society, many device with advanced technologies invented by many companies. However, the current firmware technologies have many problems to meet such high level of new technologies. In this paper, we have successfully ported linux on an embedded system, which is based on intel StrongARM SA-1 1 10 processor, then written several network modules for internet-based network devices.

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A Study on applied possibility of Organic Form In Architectural space-Design (공간구성에 있어서 유기적 형태의 응용 가능성에 관한 연구)

  • 김성혜
    • Korean Institute of Interior Design Journal
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    • no.14
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    • pp.10-18
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    • 1998
  • This study aims to make clear visual quality of organic form and structural order that is immanent in nature about a form as formative principles of architectural space design the significanced of this study is to prove the application possibility in to functional form architectural space design. All organic forms in nature has a unique shape and pattern in structure to be self-controled and good in order. Such an order in nature comes from regular construction and ratio principles which has aesthetical order by mathmetics. The specialty of beauty in nature can be revealed not only visual form but also the ratio balance and rhythm of structural principles. As we examine the aesthetic source embodied some object can be developed in to basic principles. Furthermore through this study we can find out that the form construction theory in nature forms share the quality attribute with geometrical form to be shown in architectural space design. Natural forms are ultimate visual expression of power that effects on the architectural space design. The rule of power in nature as nature formal characteristics have a direct influence and can be also applied to architectural construction. Therefore I expect that this study will be linked and continued to another structural view.

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Studies on Systematic Analysis and Management of Environmental Information (환경정보의 체계적 분석 및 관리방안 연구)

  • Kim, Myung-Jin;Chang, Chun-Ki;Lee, Jae-Woon;Kwon, Myeong-Hee;Kang, In-Goo;Seo, Chang-Wan
    • Journal of Environmental Impact Assessment
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    • v.3 no.1
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    • pp.1-8
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    • 1994
  • For managing and analyzing effectively diverse and complicated environmental informations, informations should be built systematically, and techniques should be developed. Environmental Information System(EIS) is composed of environmental informations, GIS, and manpower. Recently it is applied to Environmental Impact Assessment and environmental management, etc.. For effective application, EIS techniques will be improved. This article has four components. First, it describes building of environmental information comprising geographic and attribute data using GIS in Chuncheon district. Second, it explains programming for effective information analysis and management using AML(Are Macro Language in ARC INFO). Third, it provides specific functional capabilities including suitability analysis. Based on these analysis, this study makes some examples for systematic analysis and management of environmental information using interactive system.

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A Study on Residential Furniture Layout Preference Characteristics with the Personal Types (거주자의 성격유형별 가구배치의 선호특성에 관한 연구)

  • Kim Nam-Hyo;Suh Jeong-Yeon;Lee Sang-Ho
    • Korean Institute of Interior Design Journal
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    • v.14 no.6 s.53
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    • pp.244-251
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    • 2005
  • With the development of cognitive science and environmental psychology, there have been growing researches and discussions on the relationship between the residential design preferences and personality types. MBTI personality types have been earning popular credibility. MBTI means Myers-Briggs Type Indicator. It is based on Carl Jung's theory of psychological type. This study is based on Myers-Briggs theory to explain residential furnishing preference and explores the relationship between the four bi-polar personality types-Extroversion/Introversion, Sensing/Intuition, Thinking/Perceiving and residential furnishing preference. These tests were conducted to two hundred and twelve adult residents who live in Seoul, Korea. These tests were analyzed several significances by Chi-Square with SPSS for windows software. (E) Extroverted residents prefer layouts for interaction with guests. (I) Introverted residents prefer centripetal layout around the bed. (S) Sensing residents prefer practical and functional layouts. (N) Intuitive residents prefer personal and conceiving layouts. (T) Thinking residents prefer for attribute of space. (F) Feeling residents for familiar conversation. (J) Judging residents prefer systematic and complete layouts. (P) Perceiving residents prefer adaptable and flexible layouts. In conclusion, personality types can have a determining role in preference of residential furnishing layouts. This study suggests that residential designers should take into account clients' personality types prefer effective designing and should provide a variety of alternatives reflecting clients' preferences. This will promote clients' pleasantness and satisfaction in dwelling at home.