• 제목/요약/키워드: Functional Analysis

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Combined Effects of Physical Evidence and Functional Service at Bulgogi Restaurants on Customers' Store Image and Purchase Behaviors: Application of Video Scenario Technique

  • Hwang, Daye;Chang, Hyeja
    • 한국식생활문화학회지
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    • 제35권2호
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    • pp.181-192
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    • 2020
  • This study aimed to identify whether or not four service situations varying according to positive and negative combinations of physical evidence and functional service influence store image and purchase behavioral intentions of customers at bulgogi restaurants. The video-scenario technique was used for the study. Data were analyzed with the SPSS (Window 19.0) package using frequency analysis, one-way ANOVA, 2 by 2 factorial ANOVA, exploratory factor analysis, and multiple regression analysis to confirm the hypotheses. The combined effect of functional service and physical evidence influenced store image and purchase intention. In terms of seperate effect of physical evidence and functional service, the effect of employee service on store image was more powerful than that of physical evidence, even though the effect differed depending on the situation. Purchase intention was only influenced by functional service quality from employees under the four different scenarios. Thus, when opening a Korean restaurant, proper management of tangible evidence suitable to service, and the prices expected from local customers should be determined. Additionally, extremely high or low levels of physical evidence management should be avoided.

식물 유전자 연구의 최근 동향 (Current status on plant functional genomics)

  • 조용구;우희종;윤웅한;김홍식;우선희
    • Journal of Plant Biotechnology
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    • 제37권2호
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    • pp.115-124
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    • 2010
  • As the completion of genome sequencing, large collection of expression data and the great efforts in annotating plant genomes, the next challenge is to systematically assign functions to all predicted genes in the genome. Functional genome analysis of plants has entered the high-throughput stage. The generations and collections of mutants at the genome-wide level form technological platform of functional genomics. However, to identify the exact function of unknown genes it is necessary to understand each gene's role in the complex orchestration of all gene activities in the plant cell. Gene function analysis therefore necessitates the analysis of temporal and spatial gene expression patterns. The most conclusive information about changes in gene expression levels can be gained from analysis of the varying qualitative and quantitative changes of messenger RNAs, proteins and metabolites. New technologies have been developed to allow fast and highly parallel measurements of these constituents of the cell that make up gene activity. We have reviewed currently employed technologies to identify unknown functions of predicted genes including map-based cloning, insertional mutagenesis, reverse genetics, chemical mutagenesis, microarray analysis, FOX-hunting system, gene silencing mutagenesis, proteomics and chemical genomics. Recent improvements in technologies for functional genomics enable whole-genome functional analysis, and thus open new avenues for studies of the regulations and functions of unknown genes in plants.

An Efficient Functional Analysis Method for Micro-array Data Using Gene Ontology

  • Hong, Dong-Wan;Lee, Jong-Keun;Park, Sung-Soo;Hong, Sang-Kyoon;Yoon, Jee-Hee
    • Journal of Information Processing Systems
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    • 제3권1호
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    • pp.38-42
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    • 2007
  • Microarray data includes tens of thousands of gene expressions simultaneously, so it can be effectively used in identifying the phenotypes of diseases. However, the retrieval of functional information from a large corpus of gene expression data is still a time-consuming task. In this paper, we propose an efficient method for identifying functional categories of differentially expressed genes from a micro-array experiment by using Gene Ontology (GO). Our method is as follows: (1) The expression data set is first filtered to include only genes with mean expression values that differ by at least 3-fold between the two groups. (2) The genes are then ranked based on the t-statistics. The 100 most highly ranked genes are selected as informative genes. (3) The t-value of each informative gene is imposed as a score on the associated GO terms. High-scoring GO terms are then listed with their associated genes and represent the functional category information of the micro-array experiment. A system called HMDA (Hallym Micro-array Data analysis) is implemented on publicly available micro-array data sets and validated. Our results were also compared with the original analysis.

일부 뇌졸중 환자의 기능변화 및 관련요인 (Difference of Functional Outcome and Related Factors in Patients With Stroke)

  • 이승주;정성영
    • 한국전문물리치료학회지
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    • 제14권1호
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    • pp.46-54
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    • 2007
  • The purposes of the present study were to determine the difference of functional outcome, and to identify factors associated with functional difference in patients with stroke. The sample consisted of 56 stroke patients who had received physical therapy at the physical therapy unit of the Dongeui Medical Center in Busan city between January 2000 and June 2002. Stroke patients were evaluated by physical therapists 3 times; The first day in physical therapy (PT) (T1), one month after the first day in PT (T2), and two months after the first day in PT (T3). Functional status was assessed with the Functional Independence Measure (FIM) instrument, a validated instrument for documenting the severity of disability and assessing the outcome of rehabilitation treatment. Functional gain was calculated over T2-T1, T3-T1, and T3-T2. SAS statistical software was used for the analysis. The Student's t-test, paired t-test, analysis of variance (ANOVA/Tukey and Scheffe), and analysis of covariance (ANCOVA) were used to examine the functional difference in variables. Repeated measures ANOVA was also used to analyze the functional difference by time (T1, T2, and T3). Multiple regression analysis was performed to determine the effects of independent variables on the difference of functional outcome as defined by the FIM score. A total of 56 stroke patients were evaluated, their average age${\pm}$standard deviation was $61.6{\pm}9.3$ years (range: 40~81 yr). The functional status of patients who received physical therapy for about 2~3 months was significantly improved (mean FIM scores, $20.5{\pm}1.8$, $28.9{\pm}1.9$, and $8.41{\pm}1.1$ points for each time period, respectively) (p<.0001). Diabetes was significantly associated with the FIM score for T2-T1 (p<.05). The type of diagnosis was significantly associated with the FIM score for T3-T1 (p<.05). Gender, smoking, and the FIM score on admission were significantly associated with the FIM score for T3-T2 (p<.05). In conclusion, gender, smoking, diabetes, the type of diagnosis, and the FIM score on admission were significantly associated with improved FIM scores. We recommend that further research should explore the functional outcome by using larger sample sizes, longer follow-up periods, and more sensitive assessment instruments.

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Trait Anxiety as a Mediator of the Association between Attention Deficit Hyperactivity Disorder Symptom Severity and Functional Impairment

  • Oh, Yunhye;Yoon, Hee Joon;Kim, Ji-Hae;Joung, Yoo Sook
    • Clinical Psychopharmacology and Neuroscience
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    • 제16권4호
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    • pp.407-414
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    • 2018
  • Objective: Anxiety has been shown to influence functional impairment in patients with attention deficit hyperactivity disorder (ADHD). This study aimed to compare functional impairment in subjects with and without adult ADHD and to investigate the associations among trait anxiety, functional impairment, and ADHD symptom severity. Moreover, the effects of ADHD symptom subtypes on trait anxiety and functional impairment were also examined. Methods: The sample included 209 adults between the ages of 20 and 31 years. Fifty-one adults received a diagnosis of ADHD, and an additional age, sex-matched group of 51 adults comprised the adult control. Participants were assessed with Conners' Adult ADHD Rating Scales (CAARS), the Beck Depression Inventory (BDI), the Spielberg Trait Anxiety Inventory (STAI-T), and the Sheehan Disability Scale (SDS). The relationships among ADHD severity, anxiety, and functional impairment were investigated using Pearson's correlation analysis. Subtypes of ADHD symptoms that predicted anxiety and functional impairment were investigated using regression analyses. Results: Adult ADHD patients significantly differed from normal control subjects according to BDI, STAI-T, and SDS assessment. Significant positive correlations were noted between ADHD severity, anxiety, and functional impairment. Multiple linear regression analysis confirmed anxiety as a mediator between functional impairment and ADHD CAARS symptom subscales. Conclusion: Patients with adult ADHD showed higher levels of anxiety, depression, and functional impairment. Additionally, ADHD symptoms and anxiety impacted subject functional impairment. Our results suggest that anxiety may be a strong mediator between ADHD severity and functional impairment.

Batch and Flow-Through Column Studies for Cr(VI) Sorption to Activated Carbon Fiber

  • Lee, In;Park, Jeong-Ann;Kang, Jin-Kyu;Kim, Jae-Hyun;Son, Jeong-Woo;Yi, In-Geol;Kim, Song-Bae
    • Environmental Engineering Research
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    • 제19권2호
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    • pp.157-163
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    • 2014
  • The adsorption of Cr(VI) from aqueous solutions to activated carbon fiber (ACF) was investigated using both batch and flow-through column experiments. The batch experiments (adsorbent dose, 10 g/L; initial Cr(VI) concentration, 5-500 mg/L) showed that the maximum adsorption capacity of Cr(VI) to ACF was determined to 20.54 mg/g. The adsorption of Cr(VI) to ACF was sensitive to solution pH, decreasing from 9.09 to 0.66 mg/g with increasing pH from 2.6 to 9.9; the adsorption capacity was the highest at the highly acidic solution pHs. Kinetic model analysis showed that the Elovich model was the most suitable for describing the kinetic data among three (pseudo-first-order, pseudo-second-order, and Elovich) models. From the nonlinear regression analysis, the Elovich model parameter values were determined to be ${\alpha}$ = 162.65 mg/g/h and ${\beta}$ = 2.10 g/mg. Equilibrium isotherm model analysis demonstrated that among three (Langmuir, Freundlich, Redlich-Peterson) models, both Freundlich and Redlich-Peterson models were suitable for describing the equilibrium data. In the model analysis, the Redlich-Peterson model fit was superimposed on the Freundlich fit. The Freundlich model parameter values were determined to be $K_F$ = 0.52 L/g and 1/n = 0.56. The flow-through column experiments showed that the adsorption capacities of ACF in the given experimental conditions (column length, 10 cm; inner diameter, 1.5 cm; flow rate, 0.5 and 1.0 mL/min; influent Cr(VI) concentration, 10 mg/L) were in the range of 2.35-4.20 mg/g. This study demonstrated that activated carbon fiber was effective for the removal of Cr(VI) from aqueous solutions.

휴지기 기능적 자기공명영상의 독립성분분석기법 기반 내정상태 네트워크 기능 연결성과 확산텐서영상의 트랙토그래피 기법을 이용한 구조 연결성의 통합적 분석 (Combined Analysis Using Functional Connectivity of Default Mode Network Based on Independent Component Analysis of Resting State fMRI and Structural Connectivity Using Diffusion Tensor Imaging Tractography)

  • 최혜정;장용민
    • 한국멀티미디어학회논문지
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    • 제24권5호
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    • pp.684-694
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    • 2021
  • Resting-state Functional Magnetic Resonance Imaging(fMRI) data detects the temporal correlations in Blood Oxygen Level Dependent(BOLD) signal and these temporal correlations are regarded to reflect intrinsic cortical connectivity, which is deactivated during attention demanding, non-self referential tasks, called Default Mode Network(DMN). The relationship between fMRI and anatomical connectivity has not been studied in detail, however, the preceded studies have tried to clarify this relationship using Diffusion Tensor Imaging(DTI) and fMRI. These studies use method that fMRI data assists DTI data or vice versa and it is used as guider to perform DTI tractography on the brain image. In this study, we hypothesized that functional connectivity in resting state would reflect anatomical connectivity of DMN and the combined images include information of fMRI and DTI showed visible connection between brain regions related in DMN. In the previous study, functional connectivity was determined by subjective region of interest method. However, in this study, functional connectivity was determined by objective and advanced method through Independent Component Analysis. There was a stronger connection between Posterior Congulate Cortex(PCC) and PHG(Parahippocampa Gyrus) than Anterior Cingulate Cortex(ACC) and PCC. This technique might be used in several clinical field and will be the basis for future studies related to aging and the brain diseases, which are needed to be translated not only functional connectivity, but structural connectivity.

Seed-Based Resting-State Functional MRI for Presurgical Localization of the Motor Cortex: A Task-Based Functional MRI-Determined Seed Versus an Anatomy-Determined Seed

  • Ji Young Lee;Yangsean Choi;Kook Jin Ahn;Yoonho Nam;Jin Hee Jang;Hyun Seok Choi;So Lyung Jung;Bum Soo Kim
    • Korean Journal of Radiology
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    • 제20권1호
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    • pp.171-179
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    • 2019
  • Objective: For localization of the motor cortex, seed-based resting-state functional MRI (rsfMRI) uses the contralateral motor cortex as a seed. However, research has shown that the location of the motor cortex could differ according to anatomical variations. The purpose of this study was to compare the results of rsfMRI using two seeds: a template seed (the anatomically expected location of the contralateral motor cortex) and a functional seed (the actual location of the contralateral motor cortex determined by task-based functional MRI [tbfMRI]). Materials and Methods: Eight patients (4 with glioma, 3 with meningioma, and 1 with arteriovenous malformation) and 9 healthy volunteers participated. For the patients, tbfMRI was performed unilaterally to activate the healthy contralateral motor cortex. The affected ipsilateral motor cortices were mapped with rsfMRI using seed-based and independent component analysis (ICA). In the healthy volunteer group, both motor cortices were mapped with both-hands tbfMRI and rsfMRI. We compared the results between template and functional seeds, and between the seed-based analysis and ICA with visual and quantitative analysis. Results: For the visual analysis, the functional seed showed significantly higher scores compared to the template seed in both the patients (p = 0.002) and healthy volunteers (p < 0.001). Although no significant difference was observed between the functional seed and ICA, the ICA results showed significantly higher scores than the template seed in both the patients (p = 0.01) and healthy volunteers (p = 0.005). In the quantitative analysis, the functional seed exhibited greater similarity to tbfMRI than the template seed and ICA. Conclusion: Using the contralateral motor cortex determined by tbfMRI as a seed could enhance visual delineation of the motor cortex in seed-based rsfMRI.

계량적 접근에 의한 조선시대 필사본 조리서의 유사성 분석 (A Quantitative Approach to a Similarity Analysis on the Culinary Manuscripts in the Chosun Periods)

  • 이기황;이재윤;백두현
    • 한국언어정보학회지:언어와정보
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    • 제14권2호
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    • pp.131-157
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    • 2010
  • This article reports an attempt to perform a similarity analysis on a collection of 25 culinary manuscripts in Chosun periods using a set of quantitative text analysis methods. Historical culinary texts are valuable resources for linguistic, historic, and cultural studies. We consider the similarity of two texts as the distributional similarities of the functional components of the texts. In the case of culinary texts, text elements such as food names, cooking methods, and ingredients are regarded as functional components. We derive the similarity information from the distributional characteristics of the two key functional components, cooking methods and ingredients. The results are also quantified and visualized to achieve a better understanding of the properties of the individual texts and the collection of the texts as a whole.

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타 교과와 연결된 상황 설정을 통한 함수적 사고 지도 방안 (Teaching Method for Functional Thinking by Situation Posing Connected with Other Subjects)

  • 나경수;최성필
    • 대한수학교육학회지:학교수학
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    • 제13권4호
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    • pp.651-674
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    • 2011
  • 함수적 사고는 학교 수학에서 가장 중요한 주제이고 함수적 사고 지도의 목적은 학생들의 함수적 사고를 향상시키는 것이라고 할 때 초등학교에서 함수적 사고를 지도한다는 것은 함수적 사고의 속성인 지정과 종속의 연관이 내재된 현상을 의미하는 함수적 사고이다. 함수적 사고를 습득했는지에 대한 평가 방법은 함수적 사고의 지도를 통해 학생들이 함수적 사고를 한다고 판단할 수 있는 학생들의 활동이다. 이를 위해서 교사는 함수적 속성을 갖는 타 교과의 내용과 관련된 함수적 상황의 형태의 전형적인 예(paradigm)을 제공하고, 적절한 발문을 통해 안내해야 한다. 본 연구의 목적은 타 교과와 연결된 상황 설정을 통한 함수적 사고의 지도 방안을 구안하고 적용하여 보다 발전된 지도 방안을 모색하는 것이다. 이를 위해 본 연구에서 제안하는 지도 방안은 함수적 상황의 준비단계, 적용단계, 반성단계의 3단계로 구성되며, 각 단계에서 지도해야 할 방안들을 제안하고자 한다.

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