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Progress in human ovarian rejuvenation: Current platelet-rich plasma and condensed cytokine research activity by scope and international origin

  • Sills, E. Scott;Wood, Samuel H.
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.4
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    • pp.311-315
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    • 2021
  • Objective: As clinicians and patients await consensus on intraovarian platelet-rich plasma (PRP) treatment, this project evaluated contemporary research trends in the literature. Methods: A PubMed/NLM search aggregated all ovarian PRP-related publications (n=54) to evaluate their scope, abstract utility, submission-to-publication interval, journal selected, article processing charge (APC), free reader access to full-text manuscripts, number and nationality of authors, and inclusion of international collaborators. The NIH Clinical Trials database was also audited. Results: Published output on intraovarian PRP has increased consistently since 2016, especially among investigators in Greece, Iran, USA, and Turkey. Between 2013 and 2021, 42 articles met the relevancy criteria, of which 40.5% reported clinical studies, small series, or case reports, 33% described experimental animal models, and 23.8% were opinion/review papers. Only two works included a placebo control group. The submission-to-publication interval (mean±standard deviation) was 130±96 days, there were 5.9±3.2 authors per project, and journals invoiced US $1,613±1,466 (range, $0-$3,860) for APCs. Conclusion: There was no correlation between APC and time to publish (Pearson's r=-0.01). Abstract content was inconsistent; sample size and patient age were often missing, yet free full-text "open access" was available for most publications (59.5%). The NIH Clinical Trials portal lists eight registered studies on "ovarian rejuvenation," of which two are actively recruiting patients, while four have been terminated or have an uncertain status. Two studies have concluded, with results from one posted to the NIH website. PRP and its derivatives for ovarian treatment show early promise, but require further investigation. Research is accelerating and should be encouraged, particularly placebo-controlled randomized clinical trials.

Analysis of major indicators of department of dental hygiene in college through the university information disclosure system (대학정보공시를 이용한 치위생과 주요 지표 분석)

  • Lee, Sun-Mi
    • Journal of Korean society of Dental Hygiene
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    • v.22 no.3
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    • pp.153-160
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    • 2022
  • Objectives: This study tried to use information from the university information disclosure system as basic data to understand dental hygiene departments and search for development directions by analyzing major indicators through information disclosure data collection. Methods: Based on the information released from 2019 to 2021, 53 three-year universities with dental hygiene departments nationwide were analyzed based on data from the last three years of university alerts. Results: The indicators that the colleges with dental hygiene departments had higher averages than the overall junior colleges were: rate of levy with enrolled students within the quota, rate of faculty in full service, rate of lectures conducted by faculty in full service, employment rate, and annual scholarships per person. In the dental hygiene departments, acceptance rates of new students were 1.46-30.53 (average 10.24), admission quota was 27-160 (average 70), the number of continuing students was 39-515 (average 209), number of scholarships was 1,368,348.50 won-4,581,073.13 won (average 3,515,647.32 won) and the employment rate ranged from 57.6% to 98.9% (average 82.8%). Conclusions: In order for the departments of dental hygiene to be competitive, it is necessary for colleges to find ways to increase pride in, and satisfaction with their departments. After graduation, if the professional dental hygienist system is established and the legal role as a dental hygienist is expanded, it will be possible to move forward as a competitive department.

A Study of Practical and Optimized Mineral Quantification (실용적이고 최적화된 광물정량분석법 연구)

  • Son, Byeong-Kook;An, Gi-O
    • Korean Journal of Mineralogy and Petrology
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    • v.34 no.4
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    • pp.227-239
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    • 2021
  • A practical and effective method of X-ray powder diffraction analysis was investigated for quantitative analysis of the mineral content of natural samples. Sample mounting experiments were conducted to select the best randomly oriented powder sample mount. A comparative experiment was also made between a reference intensity ratio (RIR) method, which compares a single peak intensity with standard material, and the Rietveld method, which calculates a full X-ray diffraction pattern, to search for the effective method of mineral quantification. In addition, samples containing amorphous minerals were quantitatively analyzed by the Rietveld method and the efficiency was reviewed. As a result of the study, the optimal random orientation could be reached by the side mounting method. The Rietveld method using the full pattern of X-ray diffraction was more suitable for mineral quantitative analysis, rather than the RIR method using a specific peak. However, either method could depend on the analyst's experience in addition to analytical technique. Moreover, amorphous minerals can be quantitatively analyzed by the Rietveld method, and the analysis results make the geological analysis possible.

Methods for Integration of Documents using Hierarchical Structure based on the Formal Concept Analysis (FCA 기반 계층적 구조를 이용한 문서 통합 기법)

  • Kim, Tae-Hwan;Jeon, Ho-Cheol;Choi, Joong-Min
    • Journal of Intelligence and Information Systems
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    • v.17 no.3
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    • pp.63-77
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    • 2011
  • The World Wide Web is a very large distributed digital information space. From its origins in 1991, the web has grown to encompass diverse information resources as personal home pasges, online digital libraries and virtual museums. Some estimates suggest that the web currently includes over 500 billion pages in the deep web. The ability to search and retrieve information from the web efficiently and effectively is an enabling technology for realizing its full potential. With powerful workstations and parallel processing technology, efficiency is not a bottleneck. In fact, some existing search tools sift through gigabyte.syze precompiled web indexes in a fraction of a second. But retrieval effectiveness is a different matter. Current search tools retrieve too many documents, of which only a small fraction are relevant to the user query. Furthermore, the most relevant documents do not nessarily appear at the top of the query output order. Also, current search tools can not retrieve the documents related with retrieved document from gigantic amount of documents. The most important problem for lots of current searching systems is to increase the quality of search. It means to provide related documents or decrease the number of unrelated documents as low as possible in the results of search. For this problem, CiteSeer proposed the ACI (Autonomous Citation Indexing) of the articles on the World Wide Web. A "citation index" indexes the links between articles that researchers make when they cite other articles. Citation indexes are very useful for a number of purposes, including literature search and analysis of the academic literature. For details of this work, references contained in academic articles are used to give credit to previous work in the literature and provide a link between the "citing" and "cited" articles. A citation index indexes the citations that an article makes, linking the articleswith the cited works. Citation indexes were originally designed mainly for information retrieval. The citation links allow navigating the literature in unique ways. Papers can be located independent of language, and words in thetitle, keywords or document. A citation index allows navigation backward in time (the list of cited articles) and forwardin time (which subsequent articles cite the current article?) But CiteSeer can not indexes the links between articles that researchers doesn't make. Because it indexes the links between articles that only researchers make when they cite other articles. Also, CiteSeer is not easy to scalability. Because CiteSeer can not indexes the links between articles that researchers doesn't make. All these problems make us orient for designing more effective search system. This paper shows a method that extracts subject and predicate per each sentence in documents. A document will be changed into the tabular form that extracted predicate checked value of possible subject and object. We make a hierarchical graph of a document using the table and then integrate graphs of documents. The graph of entire documents calculates the area of document as compared with integrated documents. We mark relation among the documents as compared with the area of documents. Also it proposes a method for structural integration of documents that retrieves documents from the graph. It makes that the user can find information easier. We compared the performance of the proposed approaches with lucene search engine using the formulas for ranking. As a result, the F.measure is about 60% and it is better as about 15%.

Experimental Study on Seismic Retrofit of Steel Moment Connections Considering Constraint Effect of the Floor Slab (바닥슬래브에 의해 구속된 철골 모멘트접합부의 내진보강에 관한 실험적 연구)

  • Oh, Sang Hoon;Kim, Young Ju;Moon, Tae Sup
    • Journal of Korean Society of Steel Construction
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    • v.16 no.2 s.69
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    • pp.247-255
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    • 2004
  • An experimental program was undertaken to develop seismic retrofit methods of existing steel moment connections with floor slab for improved seismic performance. Five full-scale composite specimens were tested under cyclic loading. Conventional through-diaphragm connections [please check this; no search results were found for through-diaphragm connections] composed of square-tube column and H-beam were retrofitted by adding either a bottom-flange dogbone (RBS) or an improved welded horizontal stiffener at the beam bottom flange. The effectiveness of the proposed retrofit connections schemes was evaluated. The specimen retrofitted using the RBS concept at the bottom flange showed poor connection ductility. In contrast. specimens with the proposed horizontal stiffener details exhibited improved connection ductility.

An Adaptation System based on Personalized Web Content Items for Mobile Devices

  • Kim, Su-Do;Park, Man-Gon
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.3 no.6
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    • pp.628-646
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    • 2009
  • Users want to browse and search various web contents with mobile devices which can be used anywhere and anytime without limitations, in the same manner as desktop. But mobile devices have limited resources compared to desktop in terms of computing performance, network bandwidth, screen size for full browsing, and etc, so there are many difficulties in providing support for mobile devices to fully use desktop-based web contents. Recently, mobile network bandwidth has been greatly improved, however, since mobile devices cannot provide the same environment as desktop, users still feel inconvenienced. To provide web contents optimized for each user device, there have been studies about analyzing code to extract blocks for adaptation to a mobile environment. But since web contents are divided into several items such as menu, login, news, shopping, etc, if the block dividing basis is limited only to code or segment size, it will be difficult for users to recognize and find the items they need. Also it is necessary to resolve interface issues, which are the biggest inconvenience for users browsing in a mobile environment. In this paper, we suggest a personalized adaptation system that extracts item blocks from desktop-based web contents based on user interests, layers them, and adapts them for users so they can see preferred contents first.

A Study on the Emotional Vocabulary Based on Space Assessment of the Academic Library (대학도서관 공간 평가를 위한 감성어휘 도출에 관한 연구)

  • Noh, Dong-Jo
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.26 no.4
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    • pp.83-104
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    • 2015
  • This study intends to provide guidance for library design and assessment by eliciting the emotional vocabulary related to academic library space. In order to accomplish the goal of this study, 12 major emotional vocabularies related to academic library space were derived through 5 stages of extraction and refinement processes. Literature search and analysis of preceding research, focus group interview and survey of academic librarians and users of the academic library, evaluation of similarity through KJ Method, etc., selected 12 adjectives of emotional vocabulary as follows: diverse, satisfactory, necessary, full, clean, stable, appropriate, harmonious, open, warm, natural, and excellent.

Trieste and Malta as the base of the Mediterranean maritime Interchanges: the importance and the Value (지중해 해상 무역 거점지로서의 몰타(Malta)와 트리에스테(Trieste), 그 중요성과 역할)

  • Kim, Hee-Jung
    • Journal of Fisheries and Marine Sciences Education
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    • v.26 no.2
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    • pp.357-367
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    • 2014
  • The path of the search has been long and complex but rich in cultural, economic, religious, and human aspects. The relations between these two ports, Malta and Trieste, full of a painful and difficult but also glorious and fair history, have had their ups and downs as a theater, not so much land as the sea, and in this case the Mediterranean. This area has led to a similar vision of the historical aspects of the various dominations, and has a significant influence on the habits, customs and life of the people of Malta and Trieste. Their particularly complex history has unfolded with ups and downs, contrasting with other difficult times more happier and constructive as it has always, however, in the history of man. The purpose of this article is to analyze and arrange manifestly the history of commercial and maritime interchanges between Malta and Trieste, not achieved in Korea until now. This material has high scientific value gathering sufficient data for this article.

An Analysis on the Characteristics of Commercial Distribution in Seoul Using GIS (GIS를 이용한 서울시 상업업무기능의 분포특성 분석)

  • 이창수;김영식
    • Spatial Information Research
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    • v.4 no.1
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    • pp.55-74
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    • 1996
  • The purpose of this paper is to search the factors which influence the distribution of commercial function. Commercial function plays the most important role in determining urban spacial structure. The location of commercial function is influenced by topography, accessibility, population, and urban policy. Due to the lack of formal data these factors have not been studed to the full. But GIS makes it possible to conduct researches in analyzing these factors. The results are : (1) The index of employment density connects with topography, population, accessibility and urban policy. (2) The location of commercial function is influenced by these factors (3) GIS is a useful tool in analyzing urban spacial structure.

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An In-Depth Analysis and Improvement on Cache Mechanisms of SSD FTL (SSD FTL의 캐시 메커니즘에 대한 심층 분석 및 개선)

  • Lee, Hyung-Bong;Chung, Tae-Yun
    • IEMEK Journal of Embedded Systems and Applications
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    • v.15 no.1
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    • pp.9-16
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    • 2020
  • Recently, the capacity of SSD has been increasing rapidly due to the improvement of flash memory density. To take full advantage of these SSDs, first of all, FTL's prompt adaptation is necessary. The FTL is a translation layer existing in SSDs to overcome the drawback of the SSD that cannot be modified in place, and has garbage collection and caching functions in addition to the map table management function. In this study, we focus on caching function, compare and analyze the cache implementation methodologies, and propose improved methods. Typical cache implementations divide the cache into groups, manage and retrieve the caches in the group as a linked list. Thus, searches are made in the order of the linked list. In contrast, we propose a method of sequential searching using the search area group of a cache registered in the map table regardless of the linked list and cache group. Experimental results show that the proposed method has a 2.5 times improvement over the conventional method.