• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.11
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• pp.1645-1652
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• 2015

We investigated the anti-wrinkle efficacy of hydrolysate from oyster protein by Protamex and Neutrase for the purpose of finding materials to assist skin health originating from marine organisms. There were about 7.9% free amino acids in the oyster hydrolysate, and contents of urea, taurine, alanine, and glycine were high. Oyster hydrolysate also showed collagenase inhibitory activity and was not toxic to CCD986sk human fibroblast cells. Yield of the fractions according to the molecular weight of oyster hydrolysate was 40% for less than 1,000 Da and 60.4% for less than 5,000 Da, respectively. Antioxidative effect, procollagen production, and matrix metalloproteinase-1 inhibitory activity were highest in 1,000~3,000 Da fractions. We observed that oyster hydrolysate and its less than 5,000 Da fraction are potential functional compounds for skin health and for improving wrinkles.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.31.4-32
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• 2016

Observing the solar atmosphere with ground-based telescopes in the near-infrared has a number of advantages when compared to classical measurements in visible wavelengths. One of them comes from the magnetic sensitivity of spectral lines, which varies as ${\lambda}_g$, where g is the effective $Land{\acute{e}}$ factor of the transition. This wavelength dependence makes the near-infrared range adequate to study subtle spatial or temporal variations of the magnetic field. Spectral lines, such as the photospheric Fe I $1.5648{\mu}m$ spectral line, with a $Land{\acute{e}}$ factor g=3, have often been used in the past for this type of studies. To study the chromosphere, the Ca II IR triplet and the He I $1.0830{\mu}m$ triplet are the most often observed lines. The latter has the additional advantage that the photospheric Si I $1.0827{\mu}m$ is close enough so that photosphere and chromosphere can be simultaneously recorded with a single detector in a spectrograph. The instrument TIP (Tenerife Infrared Polarimeter) has been continuously operating since 1999 at the 70-cm German VTT of the Observatorio del Teide and has been recently moved to the 1.5-m German GREGOR. During all this time, results have been obtained concerning the nature of the weak photospheric magnetic field of the quiet sun, magneto-acoustic wave propagation, evolution with the cycle of sunspot magnetic fields, photospheric and chromospheric magnetic field in emerging regions, magnetic field in chromospheric structures such as filaments, prominences, flares, and spicules, etc. In this talk, I will review the main results obtained after all these observations and mention the main challenges for the future. With its novel polarization-free design and a complete suite of instruments aimed at simultaneous (imaging and spectroscopic) observations of the solar photosphere and chromosphere, the EST (European Solar Telescope) will represent a major world-wide infrastructure to understand the physical nature of all these phenomena.

• Journal of Digital Contents Society
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• v.18 no.5
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• pp.995-1000
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• 2017

The purpose of this study is to analyze the educational effect on creativity and solving-problem ability based on hackathon of elementary SW education. We divided into control and experimental groups with activities of physical computing or robots. The control groups conducted by traditional project based learning collaboratively and the experimental group in hackathon. The outcomes from students were evaluated to by elementary teachers with questionnaire and analyzed to the creativity and solving-problem ability of physical computing or robot productions. As a result, a group of hackathon showed significant positive results in the accuracy on creativity and solving-problem skills statistically. We concluded that the free atmosphere of hackathon for communication and consultation have been attributed to various ideas of students.

• Current Optics and Photonics
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• v.2 no.3
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• pp.241-249
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• 2018

We report a midinfrared dual-field-of-view (FOV) optical system design for an airborne electro-optical targeting system. To achieve miniaturization and weight reduction of the system, it has a common aperture and fore-optics for three different spectral wavelength bands: an electro-optic (EO) band ($0.6{\sim}0.9{\mu}m$), a midinfrared (IR) band ($3.6{\sim}4.9{\mu}m$), and a designation laser wavelength ($1.064{\mu}m$). It is free to steer the line of sight by rotating the pitch and roll axes. Our design co-aligns the roll axis, and the line of sight therefore has a fixed entrance pupil position for all optical paths, unlike previously reported dual-FOV designs, which dispenses with image coregistration that is otherwise required. The fore-optics is essentially an achromatized, collimated beam reducer for all bands. Following the fore-optics, the bands are split into the dual-FOV IR path and the EO/laser path by a beam splitter. The subsequent dual-FOV IR path design consists of a zoom lens group and a relay lens group. The IR path with the fore-optics provides two stepwise FOVs ($1.50^{\circ}{\times}1.20^{\circ}$ to $5.40^{\circ}{\times}4.32^{\circ}$), due to the insertion of two Si lenses into the zoom lens group. The IR optical system is designed in such a way that the location and f-number (f/5.3) of the cold stop internally provided by the IR detector are maintained when changing the zoom. The design also satisfies several important performance requirements, including an on-axis modulation transfer function (MTF) that exceeds 10% at the Nyquist frequency of the IR detector pitch, with distortion of less than 2%.

• Transactions on Electrical and Electronic Materials
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• v.3 no.1
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• pp.30-37
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• 2002

A focusing grating coupler (FGC) was not fabricated by the 'Continuous Path Control'writing strategy but by an electron-beam lithography system of more general exposure mode, which matches not only the address grid with the grating period but also an integer multiple of the address grid resolution (5 nm). To more simplify the fabrication, we are able to reduce a process step without large decrease of pattern quality by excluding a conducting material or layer such as metal (Al, Cr, Au), which are deposited on top or bottom of an e-beam resist to prevent charge build-up during e-beam exposure. A grating pitch period and an aperture feature size of the FGC designed and fabricated by e-beam lithography and reactive ion etching were ranged over 384.3 nm to 448.2 nm, and 0.5 $\times$ 0.5 mm$^2$area, respectively. This fabrication method presented will reduce processing time and improve the grating quality by means of a consideration of the address grid resolution, grating direction, pitch size and shapes when exposing. Here our investigations concentrate on the design and efficient fabrication results of the FGC for coupling from slab waveguide to a spot in free space.

• Journal of Gastric Cancer
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• v.16 no.1
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• pp.21-27
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• 2016

Purpose: Transducer-like enhancer of split 1 (TLE1) is a member of the Groucho/TLE family of transcriptional co-repressors that regulate the transcriptional activity of numerous genes. TLE1 is involved in the tumorigenesis of various tumors. We investigated the prognostic significance of TLE1 expression and its association with clinicopathological parameters in gastric cancer (GC) patients. Materials and Methods: Immunohistochemical analysis of six tissue microarrays was performed to examine TLE1 expression using 291 surgically resected GC specimens from the Soonchunhyang University Cheonan Hospital between July 2006 and December 2009. Results: In the non-neoplastic gastric mucosa, TLE1 expression was negative. In GC, 121 patients (41.6%) were positive for TLE1. The expression of TLE1 was significantly associated with male gender (P=0.021), less frequent lymphatic (P=0.017) or perineural invasion (P=0.029), intestinal type according to the Lauren classification (P=0.024), good histologic grade (P<0.001), early pathologic T-stage (P=0.012), and early American Joint Committee on Cancer stage (P=0.022). In the Kaplan-Meier analysis, the TLE1 expression was significantly associated with longer disease-free (P=0.022) and overall (P=0.001) survival rates. Conclusions: We suggested that TLE1 expression is a good prognostic indicator in GCs.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.6
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• pp.1696-1704
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• 2008

The conventional hard disk has been the dominant database storage system for over 25 years. Recently, hybrid systems which incorporate the advantages of flash memory into the conventional hard disks are considered to be the next dominant storage systems. Their features are satisfying the requirements like enhanced data I/O, energy consumption and reduced boot time, and they are sufficient to hybrid storage systems as major database storages. However, we need to improve traditional index management schemes based on B-Tree due to the relatively slow characteristics of hard disk operations, as compared to flashmemory. In order to achieve this goal, we propose a new index management scheme called FNC-Tree. FNC-Tree-based index management enhanced search and update performance by caching data objects in unused free area of flash leaf nodes to reduce slow hard disk I/Os in index access processes. Based on the results of the performance evaluation, we conclude that our scheme outperforms the traditional index management schemes.

• Natural Product Sciences
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• v.22 no.1
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• pp.60-63
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• 2016

The study is a pioneering effort to determine the mineral, nutritional, and phytochemical composition and phenolic content and to determine the free radical scavenging activity of Gigantochloa levis (Blanco) Merr, a native bamboo species (locally known as "bolo") in the Philippines. Proximate analysis showed that air-dried G. levis leaves contain 15.8% ash, 22.6% crude protein, 1.2% crude fat, 29.3% crude fiber, and 19.7% total sugar. Phytochemical tests indicated the presence of diterpenes, triterpenes, saponins, phenols, tannins, and flavonoids in both the ethanolic and aqueous leaf extracts, while phytosterols were only detected in the ethanolic extract. Folin-Ciocalteu assay determined the total phenolic content in gallic acid equivalents (GAE) to be $85.86{\pm}3.71$ and $32.32{\pm}1.01mg\;GAE/100g$ dried sample for the ethanolic and aqueous extracts, respectively. The total phenolic content in quercetin equivalents (QE) was $74.44{\pm}3.11$ and $29.43{\pm}0.85mg\;QE/100g$ dried sample for the ethanolic and aqueous extracts, respectively. The radical scavenging activity of the different solvent fractions containing varying concentrations of the extract was determined using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay. The ethyl acetate and 1-butanol fractions were found to have the highest radical scavenging activity. Mineral analysis via Energy Dispersive X-Ray Spectrometry (EDS) of the ash of G. levis leaves showed that Si is the major component, followed by K and Mg. These results point to the potential of G. levis leaves as a source of minerals and bioactive compounds with medicinal value.

• Journal of Radiation Industry
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• v.5 no.1
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• pp.7-13
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• 2011

The present study has been performed to compare the physiological analysis of monocot model plant (rice) in response to ionizing irradiations (cosmic-ray, gamma-ray, and Ion beam). Ionizing radiations were implanted into monocot model plant (rice) seed. After irradiation, the seeds were planted in the plastic pots for a growth period of one month. Thereafter, the morphological and physiological characteristics including malondealdehyde (MDA) and chlorophyll content, activities of antioxidant enzymes in irradiation samples were investigated. We are confirmed that the activity level of MDA and chlorophyll content were not changed by ionizing irradiation samples. However, the free radical contents were increased in all irradiated plants. And the activities of SOD, POD, and APX were significantly increased by irradiation compared with non-irradiation plant.

• Corrosion Science and Technology
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• v.18 no.5
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• pp.212-219
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• 2019

This paper reviews recent approaches to develop composite polymer-containing coatings by plasma electrolytic oxidation (PEO) using various low-molecular fractions of superdispersed polytetrafluoroethylene (SPTFE). The features of the unique approaches to form the composite polymer-containing coating on the surface of MA8 magnesium alloy were summarized. Improvement in the corrosion and tribological behavior of the polymer-containing coating can be attributed to the morphology and insulating properties of the surface layers and solid lubrication effect of the SPTFE particles. Such multifunctional coatings have high corrosion resistance ($R_p=3.0{\times}10^7{\Omega}cm^2$) and low friction coefficient (0.13) under dry wear conditions. The effect of dispersity and ${\xi}$-potential of the nanoscale materials ($ZrO_2$ and $SiO_2$) used as electrolyte components for the plasma electrolytic oxidation on the composition and properties of the coatings was investigated. Improvement in the protective properties of the coatings with the incorporated nanoparticles was explained by the greater thickness of the protective layer, relatively low porosity, and the presence of narrow non-through pores. The impedance modulus measured at low frequency for the zirconia-containing layer (${\mid}Z{\mid}_{f=0.01Hz}=1.8{\times}10^6{\Omega}{\cdot}cm^2$) was more than one order of magnitude higher than that of the PEO-coating formed in the nanoparticles-free electrolyte (${\mid}Z{\mid}_{f=0.01Hz}=5.4{\times}10^4{\Omega}{\cdot}cm^2$).