• 제목/요약/키워드: Fractional order model

검색결과 116건 처리시간 0.022초

A FRACTIONAL-ORDER TUMOR GROWTH INHIBITION MODEL IN PKPD

  • Byun, Jong Hyuk;Jung, Il Hyo
    • East Asian mathematical journal
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    • 제36권1호
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    • pp.81-90
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    • 2020
  • Many compartment models assume a kinetically homogeneous amount of materials that have well-stirred compartments. However, based on observations from such processes, they have been heuristically fitted by exponential or gamma distributions even though biological media are inhomogeneous in real environments. Fractional differential equations using a specific kernel in Pharmacokinetic/Pharmacodynamic (PKPD) model are recently introduced to account for abnormal drug disposition. We discuss a tumor growth inhibition (TGI) model using fractional-order derivative from it. This represents a tumor growth delay by cytotoxic agents and additionally show variations in the equilibrium points by the change of fractional order. The result indicates that the equilibrium depends on the tumor size as well as a change of the fractional order. We find that the smaller the fractional order, the smaller the equilibrium value. However, a difference of them is the number of concavities and this indicates that TGI over time profile for fitting or prediction should be determined properly either fractional order or tumor sizes according to the number of concavities shown in experimental data.

ANALYSIS OF MALARIA DYNAMICS USING ITS FRACTIONAL ORDER MATHEMATICAL MODEL

  • PAWAR, D.D.;PATIL, W.D.;RAUT, D.K.
    • Journal of applied mathematics & informatics
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    • 제39권1_2호
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    • pp.197-214
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    • 2021
  • In this paper, we have studied dynamics of fractional order mathematical model of malaria transmission for two groups of human population say semi-immune and non-immune along with growing stages of mosquito vector. The present fractional order mathematical model is the extension of integer order mathematical model proposed by Ousmane Koutou et al. For this study, Atangana-Baleanu fractional order derivative in Caputo sense has been implemented. In the view of memory effect of fractional derivative, this model has been found more realistic than integer order model of malaria and helps to understand dynamical behaviour of malaria epidemic in depth. We have analysed the proposed model for two precisely defined set of parameters and initial value conditions. The uniqueness and existence of present model has been proved by Lipschitz conditions and fixed point theorem. Generalised Euler method is used to analyse numerical results. It is observed that this model is more dynamic as we have considered all classes of human population and mosquito vector to analyse the dynamics of malaria.

Modeling and Analysis of the Fractional Order Buck Converter in DCM Operation by using Fractional Calculus and the Circuit-Averaging Technique

  • Wang, Faqiang;Ma, Xikui
    • Journal of Power Electronics
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    • 제13권6호
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    • pp.1008-1015
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    • 2013
  • By using fractional calculus and the circuit-averaging technique, the modeling and analysis of a Buck converter with fractional order inductor and fractional order capacitor in discontinuous conduction mode (DCM) operations is investigated in this study. The equivalent averaged circuit model of the fractional order Buck converter in DCM operations is established. DC analysis is conducted by using the derived DC equivalent circuit model. The transfer functions from the input voltage to the output voltage, the duty cycle to the output voltage, the input impedance, and the output impedance of the fractional order Buck converter in DCM operations are derived from the corresponding AC-equivalent circuit model. Results show that the DC equilibrium point, voltage ratio, and all derived transfer functions of the fractional order Buck converter in DCM operations are affected by the inductor order and/or capacitor order. The fractional order inductor and fractional order capacitor are designed, and PSIM simulations are performed to confirm the correctness of the derivations and theoretical analysis.

Fractional Order Modeling and Control of Twin Rotor Aero Dynamical System using Nelder Mead Optimization

  • Ijaz, Salman;Hamayun, Mirza Tariq;Yan, Lin;Mumtaz, Muhammad Faisal
    • Journal of Electrical Engineering and Technology
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    • 제11권6호
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    • pp.1863-1871
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    • 2016
  • This paper presents an application of fractional order controller for the control of multi input multi output twin rotor aerodynamic system. Dynamics of the considered system are highly nonlinear and there exists a significant cross-coupling between the horizontal and vertical axes (pitch & yaw). In this paper, a fractional order model of twin rotor aerodynamic system is identified using input output data from nonlinear system. Based upon identified fractional order model, a fractional order PID controller is designed to control the angular position of level bar of twin rotor aerodynamic system. The parameters of controller are tuned using Nelder-Mead optimization and compared with particle swarm optimization techniques. Simulation results on the nonlinear model show a significant improvement in the performance of fractional order PID controller as compared to a classical PID controller.

Image Denoising Based on Adaptive Fractional Order Anisotropic Diffusion

  • Yu, Jimin;Tan, Lijian;Zhou, Shangbo;Wang, Liping;Wang, Chaomei
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제11권1호
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    • pp.436-450
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    • 2017
  • Recently, the method based on fractional order partial differential equation has been used in image processing. Usually, the optional order of fractional differentiation is determined by a lot of experiments. In this paper, a denoising model is proposed based on adaptive fractional order anisotropic diffusion. In the proposed model, the complexity of the local image texture is reflected by the local variance, and the order of the fractional differentiation is determined adaptively. In the process of the adaptive fractional order model, the discrete Fourier transform is applied to compute the fractional order difference as well as the dynamic evolution process. Experimental results show that the peak signal-to-noise ratio (PSNR) and structural similarity index measurement (SSIM) of the proposed image denoising algorithm is better than that of other some algorithms. The proposed algorithm not only can keep the detailed image information and edge information, but also obtain a good visual effect.

Stability analysis in BWRs with double subdiffusion effects: Reduced order fractional model (DS-F-ROM)

  • Gilberto Espinosa-Paredes;Ricardo I. Cazares-Ramirez;Vishwesh A. Vyawahare;Erick-G. Espinosa-Martinez
    • Nuclear Engineering and Technology
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    • 제56권4호
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    • pp.1296-1309
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    • 2024
  • The aim of this work is to explore the effect of the double subdiffusion on the stability in BWRs. A BWR novel reduced order model with double subdiffusion effects: reduced order fractional model (DS-F-ROM) to describe the neutron and heat transfer processes was proposed for this study. The double subdiffusion was developed with a fractional-order two-equation model, and with different fractional-orders and relaxation times. The stability analysis was carried out using the root-locus method and change from the s to the W domain and were confirmed using the time-domain evolution of neutron flux for a unit step change in reactivity. The results obtained using the reduced fractional-order model are presented for different anomalous diffusion coefficient values. Results are compared with normal diffusion and P1 equations, which are obtained straightforwardly with DS-ROM when relaxation time tends to zero, and when the anomalous diffusion coefficient tends to one, respectively.

비정수 차수를 갖는 비례적분미분제어법과 가우시안 혼합모델을 이용한 연속아연도금라인에서의 전자기 제진제어 기술 (Electromagnetic Strip Stabilization Control in a Continuous Galvanizing Line using Mixture of Gaussian Model Tuned Fractional PID Controller)

  • 구배영;원상철
    • 제어로봇시스템학회논문지
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    • 제21권8호
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    • pp.718-722
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    • 2015
  • This paper proposes a fractional-order PID (Proportional-Integral-Derivative) control used electromagnetic strip stabilization controller in a continuous galvanizing line. Compared to a conventional PID controller, a fractional-order PID controller has integration-fractional-order and derivation-fractional-order as additional control parameters. Thanks to increased control parameters, more precise controller adjustment is available. In addition, accurate transfer function of a real system generally has a fractional-order form. Therefore, it is more adequate to use a fractional-order PID controller than a conventional PID controller for a real world system. Finite element models of a $1200{\times}2000{\times}0.8mm$ strip, which were extracted using a commercial software ANSYS were used as simulation plants, and Gaussian mixture models were used to find optimized control parameters that can reduce the strip vibrations to the lowest amplitude. Simulation results show that a fractional-order PID controller significantly reduces strip vibration and transient response time than a conventional PID controller.

Fluid viscous device modelling by fractional derivatives

  • Gusella, V.;Terenzi, G.
    • Structural Engineering and Mechanics
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    • 제5권2호
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    • pp.177-191
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    • 1997
  • In the paper, a fractional derivative Kelvin-Voigt model describing the dynamic behavior of a special class of fluid viscous dampers, is presented. First of all, in order to verify their mechanical properties, two devices were tested the former behaving as a pure damper (PD device), whereas the latter as an elastic-damping device (ED device). For both, quasi-static and dynamic tests were carried out under imposed displacement control. Secondarily, in order to describe their cyclical behavior, a model composed by an elastic and a damping element connected in parallel was defined. The elastic force was assumed as a linear function of the displacement whereas the damping one was expressed by a fractional derivative of the displacement. By setting an appropriate numerical algorithm, the model parameters (fractional derivative order, damping coefficient and elastic stiffness) were identified by experimental results. The estimated values allowed to outline the main parameter properties on which depend both the elastic as well as the damping behavior of the considered devices.

3D stress-fractional plasticity model for granular soil

  • Song, Shunxiang;Gao, Yufeng;Sun, Yifei
    • Geomechanics and Engineering
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    • 제17권4호
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    • pp.385-392
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    • 2019
  • The present fractional-order plasticity models for granular soil are mainly established under the triaxial compression condition, due to its difficult in analytically solving the fractional differentiation of the third stress invariant, e.g., Lode's angle. To solve this problem, a three dimensional fractional-order elastoplastic model based on the transformed stress method, which does not rely on the analytical solution of the Lode's angle, is proposed. A nonassociated plastic flow rule is derived by conducting the fractional derivative of the yielding function with respect to the stress tensor in the transformed stress space. All the model parameters can be easily determined by using laboratory test. The performance of this 3D model is then verified by simulating multi series of true triaxial test results of rockfill.

FRACTIONAL POLYNOMIAL METHOD FOR SOLVING FRACTIONAL ORDER POPULATION GROWTH MODEL

  • Krishnarajulu, Krishnaveni;Krithivasan, Kannan;Sevugan, Raja Balachandar
    • 대한수학회논문집
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    • 제31권4호
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    • pp.869-878
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    • 2016
  • This paper presents an ecient fractional shifted Legendre polynomial method to solve the fractional Volterra's model for population growth model. The fractional derivatives are described based on the Caputo sense by using Riemann-Liouville fractional integral operator. The theoretical analysis, such as convergence analysis and error bound for the proposed technique has been demonstrated. In applications, the reliability of the technique is demonstrated by the error function based on the accuracy of the approximate solution. The numerical applications have provided the eciency of the method with dierent coecients of the population growth model. Finally, the obtained results reveal that the proposed technique is very convenient and quite accurate to such considered problems.