• Title/Summary/Keyword: Formulation development

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Chemical and toxicological properties of controlled release granular formulations of acetamiprid using wax matrix (왁스매트릭스를 이용한 방출조절헝 acetamiprid 입제의 화학적, 독성학적 특성)

  • Lee, Weon-Kee;Yang, Kyung-Hyung;Lee, Chang-Hyuk;Lee, Seung-Il;Hwang, In-Cheon
    • The Korean Journal of Pesticide Science
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    • v.9 no.3
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    • pp.243-249
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    • 2005
  • The chemical and toxicological studies were conducted with acetamiprid 2% granules including different controlling agents for development of controlled-release acetamiprid 2% granule. The fundamental formulation recipe of acetamiprid 2% granule was prepared by the insoluble matrix using polyethylene wax. Starch, cellulose and mineral (calcium carbonate) were used as controlling agents. As a result of studies, release rate of active ingredient from granules into water static condition at $25^{\circ}C$ was increased by addition of starch and cellulose, but was decreased by addition of calcium carbonate. We could select calcium carbonate as controlling agent and make three granules which there were difference in release profiles of active ingredient according to contents of polyethylene wax. 24 hours-release rates of acetamiprid from three granules into water static condition at $25^{\circ}C$ were respectively 75, 50 and 25% when contents of wax were 2, 10 and 20%. The granule which 24 hours-release rate was 25% showed lower acute toxicity against mice and rats.

Development of Decision Support System for the Design of Steel Frame Structure (강 프레임 구조물 설계를 위한 의사 결정 지원 시스템의 개발)

  • Choi, Byoung Han
    • Journal of Korean Society of Steel Construction
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    • v.19 no.1
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    • pp.29-41
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    • 2007
  • Structural design, like other complex decision problems, involves many trade-offs among competing criteria. Although mathematical programming models are becoming increasingly realistic, they often have design limitations, that is, there are often relevant issues that cannot be easily captured. From the understanding of these limitations, a decision-support system is developed that can generate some useful alternatives as well as a single optimum value in the optimization of steel frame structures. The alternatives produced using this system are "good" with respect to modeled objectives, and yet are "different," and are often better, with respect to interesting objectives not present in the model. In this study, we created a decision-support system for designing the most cost-effective moment-resisting steel frame structures for resisting lateral loads without compromising overall stability. The proposed approach considers the cost of steel products and the cost of connections within the design process. This system makes use of an optimization formulation, which was modified to generate alternatives of optimum value, which is the result of the trade-off between the number of moment connections and total cost. This trade-off was achieved by reducing the number of moment connections and rearranging them, using the combination of analysis based on the LRFD code and optimization scheme based on genetic algorithms. To evaluate the usefulness of this system, the alternatives were examined with respect to various design aspects.

Development of Adhesive Resins Formulated with Rapeseed Flour Hydrolyzates for Laminated Veneer Lumber and Its Performance Evaluation (유채박을 이용한 단판적층재용 접착제의 개발 및 성능평가)

  • Yang, In;Han, Gyu-Seong;Choi, In-Gyu;Kim, Yong-Hyun;Ahn, Sye-Hee;Oh, Sei-Chang
    • Journal of the Korean Wood Science and Technology
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    • v.39 no.3
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    • pp.221-229
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    • 2011
  • Due to the increase of oil price and the environmental issue such as the emission of volatile organic compounds, the necessity for developing alternative resins of petroleum-based adhesive resins, which have extensively been used for the manufacture of wood-based products, has been speculation since the early 1990. In our study, rapeseed flour (RSF), which is the by-product of bio-diesel produced from rapeseed, were hydrolyzed by enzymes. As a crosslinking agents of the RSF hydrolyzates, phenol-formaldehyde prepolymers (PF) were prepared. The RSF hydrolyzates and PF were mixed to complete the formulation of RSF-based adhesive resins, and the resins were applied to make the laminated veneer lumber (LVL). The physical and mechanical properties of the LVL were measured to examine whether RSF can be used as raw materials of adhesive resins for the fabrication of LVL or not. The average moisture content and soaking delamination rate of the LVL bonded with RSF-based adhesive resins exceeded the minimum requirement of KS standard. Moreover, thermal analysis of the RSF-based resins showed similar tendencies except for the RSF-based adhesive resins formulated with pectinase-hydrolyzed RSF. The bending strengths of the LVL were higher than that of the LVL made with commercial PF resins. These results showed the potential of RSF as a raw material of alternative adhesives for the production of LVL. Further works on the optimal conditions of RSF hydrolysis and spreading characteristics for RSF-based adhesive resins is required to improve the adhesive performance of RSF-based resins.

Development of Herbal Chicken Porridge and the Establishment of Optimizing the Mixing Ratio (한방 닭죽 개발 및 최적 배합비율 확립)

  • Kim, Kyung-Yeon;Baik, Moo-Yeol;Park, Cheon-Seok;Choi, Sung-Won;Kim, Chang-Nam;Kim, Byung-Yong
    • The Korean Journal of Food And Nutrition
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    • v.26 no.1
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    • pp.22-28
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    • 2013
  • The objectives of this study were to develop porridge with medicinal herbs and chicken breast meat and to find out the optimum mixing ratio. Several herb extracts such as Acanthopanacis senticosus, Rehmannia glutinosa, Disocorea japonica, and Poria cocos Wolf were used in the ratio of 2, 1, 1, and 1, respectively. The optimum processing condition for herbal chicken porridge was determined by a design expert program. Seventeen experimental points were selected, and herb extracts (82~101 g), chicken breast meat (30~50 g), and glutinous rice (40~60 g) were chosen as the independent variables. The measured responses were preference of taste, DPPH radical scavenging, SOD-like activity, and cost. The optimum formulation of herbal chicken porridge using the numerical analysis was set at herbal extracts (101 g), chicken breast meat (38.66 g), and glutinous rice (41.34 g) with a 0.714 desirability value. DPPH radical scavenging effect, preference of taste and the cost showed a linear model, whereas SOD-like activity showed a quadratic model indicating a higher interaction among the mixture. As a result of proximate composition of optimized herbal chicken porridge, the contents of moisture, carbohydrate, crude protein, crude lipid, and ash contents were 76.4, 9.0, 1.4, 0.5, and 1.6%, the calories of the porridge was 46.1 kcal/100 g.

Program Development to Evaluate Permeability Tensor of Fractured Media Using Borehole Televiewer and BIPS Images and an Assessment of Feasibility of the Program on Field Sites (시추공 텔리뷰어 및 BIPS의 영상자료 해석을 통한 파쇄매질의 투수율텐서 계산 프로그램 개발 및 현장 적용성 평가)

  • 구민호;이동우;원경식
    • The Journal of Engineering Geology
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    • v.9 no.3
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    • pp.187-206
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    • 1999
  • A computer program to numerically predict the permeability tensor of fractured rocks is developed using information on discontinuities which Borehole Televiewer and Borehole Image Processing System (BIPS) provide. It uses orientation and thickness of a large number of discontinuities as input data, and calculates relative values of the 9 elements consisting of the permeability tensor by the formulation based on the EPM model, which regards a fractured rock as a homogeneous, anisotropic porous medium. In order to assess feasibility of the program on field sites, the numerically calculated tensor was obtained using BIPS logs and compared to the results of pumping test conducted in the boreholes of the study area. The degree of horizontal anisotropy and the direction of maximum horizontal permeability are 2.8 and $N77^{\circ}CE$, respectively, determined from the pumping test data, while 3.0 and $N63^{\circ}CE$ from the numerical analysis by the developed program. Disagreement between two analyses, especially for the principal direction of anisotropy, seems to be caused by problems in analyzing the pumping test data, in applicability of the EPM model and the cubic law, and in simplified relationship between the crack size and aperture. Aside from these problems, consideration of hydraulic parameters characterizing roughness of cracks and infilling materials seems to be required to improve feasibility of the proposed program. Three-dimensional assessment of its feasibility on field sites can be accomplished by conducting a series of cross-hole packer tests consisting of an injecting well and a monitoring well at close distance.

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Development of Aqueous/Semi-Aqueous Cleaning Agent and its Field Application to Cleaning Process of Electronic Parts (수계/준수계 세정제의 개발 및 전자부품 세정공정 현장적용 연구)

  • Kim, Han-Seong;Cha, An-Jeong;Bae, Jae-Heum;Lee, Ha-Yeoul;Lee, Myung-Jin;Park, Byeong-Deog
    • Clean Technology
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    • v.10 no.2
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    • pp.61-72
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    • 2004
  • In this study, aqueous/semi-aqueous cleaning agents which consist of organic solvent, surfactant, cosurfactant, and water were developed by changing formulation parameters such as organic solvent type and contents, surfactant type and contents, and cosurfactant/surfactant(A/S) ratio, etc.. And physical properties and flux removal of the formulated cleaning agents have been evaluated. Also, the performance of oil-water separation from the rinse water contaminated during the cleaning process was evaluated for its recycling. The formulated cleaning agents in this work expected to have good penetration because of their low viscosity and low surface tension values of 30.2~32.5 dyne/cm. The flux removal with the terpene type cleaning agent was higher than that with hydrocarbon type cleaning agent and two commercial products (CPA(commercial product A), CPB(commercial product B)). And the performance of oil-water separation by gravity settling from the rinse water contaminated with formulated cleaning agent and soils was shown to be very good. The cleaning agents developed in this work were applied to surface mounting technology(SMT) cleaning process for manufacturing electronic parts at L electronic company. As a result, the newly developed cleaning agents showed two times better cleaning speed for removal of solder cream than the conventional ond containing ethanol and IPA(isopropyl alcohol). In addition, malodor and VOC problems generated by the previous organic cleaning agents have been solved in the manufacturing field through introduction of the non-volatile and environmental-friendly cleaning agents to the field.

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Estimation of Seismic Performance and Earthquake Damage Ratio of Existing Reinforced Concrete Buildings in Japan (일본의 기존 철근콘트리트건물의 내진성능 및 지진피해율의 평가)

  • 이강석;이리형
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.13 no.1
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    • pp.63-74
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    • 2000
  • The main objective of this paper is to apply as the basic data for development of a methodology to discuss the future earthquake preparedness measures in Korea by investigating the concept and applicabilities of the Japanese Standard for Evaluation of Seismic Performance of Existing RC Buildings developed in Japan among the methodologies of all the countries of the world. This paper describes the seismic performance, Is-index, of existing RC buildings in Tokyo, Japan evaluated by the Japanese Standard, also the relationships between Is-index distribution of existing RC buildings in Tokyo and that of Shizuoka and Chiba Prefecture reported already in reference[4][5][6] are investigated. And from the comparison with Is-index to buildings damaged by earthquakes experienced in Japan, the damage ratio due to severe earthquake of 3 districts mentioned above is estimated based on the probabilistic point of view. The results of this study can be utilized to identify urgently required earthquake preparedness measures with highest priority in existing RC buildings, and the methodology to evaluate the seismic performance of existing RC buildings in Japan, statistics analysis method and the methodology to estimate earthquake damage ratio based on the probabilistic point of view shown in this study can be recommended to develop a methodology to discuss the future earthquake preparedness measures in Korea.

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A Study on Social Media Sentiment Analysis for Exploring Public Opinions Related to Education Policies (교육정책관련 여론탐색을 위한 소셜미디어 감정분석 연구)

  • Chung, Jin-Myeong;Yoo, Ki-Young;Koo, Chan-Dong
    • Informatization Policy
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    • v.24 no.4
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    • pp.3-16
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    • 2017
  • With the development of social media services in the era of Web 2.0, the public opinion formation site has been partially shifted from the traditional mass media to social media. This phenomenon is continuing to expand, and public opinions on government polices created and shared on social media are attracting more attention. It is particularly important to grasp public opinions in policy formulation because setting up educational policies involves a variety of stakeholders and conflicts. The purpose of this study is to explore public opinions about education-related policies through an empirical analysis of social media documents on education policies using opinion mining techniques. For this purpose, we collected the education policy-related documents by keyword, which were produced by users through the social media service, tokenized and extracted sentimental qualities of the documents, and scored the qualities using sentiment dictionaries to find out public preferences for specific education policies. As a result, a lot of negative public opinions were found regarding the smart education policies that use the keywords of digital textbooks and e-learning; while the software education policies using coding education and computer thinking as the keywords had more positive opinions. In addition, the general policies having the keywords of free school terms and creative personality education showed more negative public opinions. As much as 20% of the documents were unable to extract sentiments from, signifying that there are still a certain share of blog posts or tweets that do not reflect the writers' opinions.

Analysis of Influenza Virus Isolates in Seoul during 2003-2004 Season (2003-2004 절기 서울지역의 인플루엔자 바이러스 분리 및 아형 분석)

  • Hwang Young-Ok;Lee Jae-In;Seo Byung-tae
    • Korean Journal of Microbiology
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    • v.41 no.1
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    • pp.53-59
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    • 2005
  • Influenza is an important public health problem which occurs almost every winter in temperate climates and is often associated with increased rates of hospitalization and death. In 1999, our influenza surveillance was initiated with 4 voluntary sentinel physicians and the Public Health Center. During the 2003-2004 influenza season, 124 influenza viruses were isolated from 401 clinical specimens, which were collected from patients with Influenza-like illness(ILI) in Seoul. The case definition of ILI is a case with fever more than $38^{\circ}C$ and systemic symptoms; cough, or sore throat. ILI was the highest at the 20-49 age $group(23\%)$ and the rate of virus isolation was the highest at the 7-19 age $group(50\%)$. Among 124 influenza viruses, isolates 83 were identified as A/H3N2 type and others were subtyped as influenza B viruses in 2003-2004 season. Influenza viruses were collected $39.1\%$ at Nowon-Gu, $13.5\%$ Gangnam-Gu and Seocho-Gu etc. and the isolate rate of virus had the area difference; Yongsan-Gu $66.7\%$, Gangnam-gu $50.0\%$, Nowon-Gu $39.9\%$, Kangbuk-Gu $36.8\%$, Seocho-Gu $27.8\%$, Dongjak-Gu $21.2\%$. Out of 401 individuals, 160 was vaccinated $(40\%)$ and the vaccination rate was the highest at the 20-49 age $group(32\%)$. These findings may contribute to the recommondation of the influenza vaccine formulation and the development of influenza control measure.

Quality Characteristics of Korean Wheat Noodle by Formulation of Foreign Wheat Flour and Starch (수입밀과 전분의 혼합 비율을 달리하여 제조한 우리밀국수의 품질특성)

  • 박동준;구경형;김철진;이수정;양정례;김양하;김종태
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.32 no.1
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    • pp.67-74
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    • 2003
  • Quality characteristics of dough and noodles prepared from Korean wheat flours (Gru and Tapdong) were evaluated by substituting foreign wheat flours and starch in the formula. Korean wheat flours showed greater water absorption and weakness as well as protein and ash contents, but lower stability than the foreign wheat (control) By increasing substituted foreign wheat flours, water absorption of domestic Gru and Tapdong decreased. Dough development time decreased for Tapdong by substituting up to 30% with foreign wheat flours. When imported wheat flours added in Gru and Tapdong, weakness of dough was decreased. Adhesiveness of dough was increased in all samples according to water adding, and Gru particulary showed the most high adhesiveness at 65% water and 10~20% replacement. From the mechanical texture test, Tapdong noodles were increased in cutting force by increasing amounts of imported wheat but decreased in extension distance. However, Cru noodles showed the opposite tendency. Hardness, adhesiveness, and chewiness of noodles were increased in all samples by increasing amounts of substitution with imported starch. As a result of cooked noodles test, Korean wheat noodles showed relatively lower values in cutting force and extension distance than in those of the control Studies of noodle-related characteristics of Korean wheat flours indicated that domestic soft wheat such as Gru might have high quality above the foreign wheat in noodle preparation by adding flours containing high amylose or low gluten.