• Journal of the Korean Wood Science and Technology
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• 제46권6호
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• pp.692-702
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• 2018

Streptococcus mutans causes oral diseases, including tooth decay, by producing a biofilm called plaque. Therefore, inhibition of biofilm formation is essential for maintaining oral health. Plants produce a variety of secondary metabolites, which act as starting sources for the discovery of new bioactive chemicals that inhibit biofilm formation of S. mutans. Previous studies have reported on chemicals with antibiotic activity for the inhibition of biofilm formation by S. mutans. In this study, nine plant extracts from Melonis Pedicellus, Agastachis Herba, Mori Cortex Radicis, Diospyros kaki leaves, Agrimoniae Herba, Polygoni Multiflori Radix, Lycopi Herba, Elsholtziae Herba, and Schizonepetae Spica were screened for the inhibition of biofilm formation from a plant extract library. The water-soluble compounds of the extracts did not affect cell growth but selectively inhibited biofilm formation. These results suggest that the selected plant extracts constitute novel biofilm formation inhibitors, with a novel biological mechanism, for improving oral hygiene.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2000년도 제21회 KOSCO SYMPOSIUM 논문집
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• pp.229-235
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• 2000

Soot formation characteristics in counterflow diffusion flames of ethylene/propane/nitrogen mixtures have been studied experimentally to investigate the soot formation mechanism. The effect of HACA reaction on PAH and soot growth has been experimentally investigated by using 2-D planar LII and PAH LIF techniques.

• 한국세라믹학회지
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• 제31권10호
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• pp.1181-1187
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• 1994

Sr-ferrite powders were synthesized by molten salt method. The process of powder formation was investigated by controlling the size and shape (sphere and acicular) of starting materials. The morphology of resulting ferrite was plate-like regardless of the shape of starting materials, Fe2O3 powders. As a result, the formation of Sr-ferrite in the molten salt was proceeded by solution-precipitation.

• 한국분말재료학회지
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• 제9권1호
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• pp.38-42
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• 2002

Effects of chemical compositions on the sintering behavior of the lead borosilicate glass developed for barrier ribs of plasma display panels were investigated in this study. Formation of pores during sintering of the glass was noted and their formation mechanism was investigated using XPS, TG/DTA, and XRD. The results indicated that pores are formed by the oxygen released from Pb-oxides during sintering.

• 한국안전학회지
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• 제16권2호
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• pp.22-26
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• 2001

The machining process on be considered as a planned interaction of the workpiece, the tool and the machine tool. In an unmanned situation, the results of this interaction are to be continuously monitored so that any changes in the machining environment on be sensed to corrective actions. In order to design the process monitoring system for unmanned manufacturing, the identification of chip formation is proposed. The system proposes the method of using acoustic emission(AE) signal analysis to identify the chip formation during cutting.

• International Journal of Oral Biology
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• 제43권4호
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• pp.171-175
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• 2018

Quorum sensing (QS) is a cell density-dependent communication mechanism between bacteria through small signaling molecules. When the number of QS signaling molecules reaches a threshold, they are transported back into the cells or recognized by membrane-bound receptors, triggering gene expression which affects various phenotypes including bioluminescence, virulence, adhesion, and biofilm formation. These phenotypes are beneficial for bacterial survival in harsh environments. This review summarizes the application of QS inhibitors for control of biofilm formation and virulence expression of periodontal pathogens.

• Bulletin of the Korean Chemical Society
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• 제32권1호
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• pp.179-182
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• 2011

Second-order rate constants ($k_{OH^-}$) have been measured spectrophotometrically for reactions of Y-substituted phenyl phenyl thionocarbonates (4a-i) with $OH^-$ in 80 mol % $H_2O$/20 mol % DMSO at $25.0{\pm}0.1^{\circ}C$. The $k_{OH^-}$ values for the reactions of 4a-i have been compared with those reported previously for the corresponding reactions of Y-substituted phenyl phenyl carbonates (3a-i) to investigate the effect of changing the electrophilic center from C=O to C=S on reactivity and mechanism. Thionocarbonates 4a-i are less reactive than the corresponding carbonates 3a-i although 4a-i are expected to be more reactive than 3a-i. The Bronsted-type plot for reactions of 4a-i is linear with $\beta_{lg}$ = -0.33, a typical $\beta_{lg}$ value for reactions reported to proceed through a stepwise mechanism with formation of an intermediate being the rate-determining step (RDS). Furthermore, the Hammett plot correlated with $\sigma^o$ constants results in much better linearity than that correlated with $\sigma^-$ constants, indicating that expulsion of the leaving group is not advanced in the RDS. Thus, alkaline hydrolysis of 4a-i has been concluded to proceed through a stepwise mechanism with formation of an intermediate being RDS, which is in contrast to the forced concerted mechanism reported for the corresponding reactions of 3a-i. Enhanced stability of the intermediate upon modification of the electrophilic center from C=O to C=S has been concluded to be responsible for the contrasting mechanisms.

• 약학회지
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• 제37권1호
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• pp.95-99
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• 1993

Peroxidase activity of cytochrome P-450 was examined using N, N-dimethylaniline (NDA) as a substrate and cumene hydroperoxide (CHP) as an oxidant. The initial rates of the N-demethylation for varied concentrations of NDA (0.05-0.5 mM) by P-450 at different fixed concentrations of CHP (0.02-0.2 mM) were determined. The results suggest that P-450 proceeds its peroxidative reaction by the rapid equilibrium random bi bi mechanism to form a ternary complex with substrate and oxidant as an active intermediate.

• 한국주조공학회지
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• 제17권4호
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• pp.327-337
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• 1997

The current understanding of the mechanism of inoculation of the eutectic in commercial Fe-C-Si alloys using either silicon containing alloys or graphite has been discussed. The mechanism whereby inclusion formation within a cast iron melt is essential for inoculation effectiveness in ferro silicon inoculation has been reviewed. The role of graphitic inoculants has been presented, including the results of recent research that confirms the inoculating capability of graphite and demonstrates those factors which must be considered in evaluating inoculation effectiveness. Fading of inoculation, both ferro silicon and graphite, and the mechanism whereby this occurs, has also been discussed.

• 한국경제지리학회지
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• 제20권4호
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• pp.486-502
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• 2017

본 연구는 한국 청정개발체제 산업의 형성 과정과 네트워크에 대한 분석을 통하여, 특정 장소에서 발생하는 산업 형성의 요인과 산업 변화의 동인을 도출하는 것을 목적으로 하였다. 설문 조사 및 심층 면담 조사를 통하여 기업 행위자의 적응 활동에 따른 네트워크의 진화와 이의 창발적 현상으로서의 산업 변화를 분석하였다. 한국 청정개발체제 산업의 발생에는 국제적 제도로 인한 조건에 국내 기업들의 산업 활동이 부합하였다는 우연성이 작용하였다. 그러나 산업의 형성에는 발전사의 신재생에너지 발전 프로젝트를 유도하여 시장을 확대하는 방향에서 수행된 정부 정책이 산업 형성을 가속화하는 촉매 역할을 수행하였다. 구조재편 상황에서는 정부 정책이 온실가스 감축과 관련된 국내 새로운 산업 형성의 초기 조건을 형성하였다. 이 과정에서 해외의 관련 지식을 국내 착근화하고 국내 외의 프로젝트에서 기반으로 활용하도록 하는 지식의 국지화가 중요한 동인으로 작용하였다.