• Title/Summary/Keyword: Foreign body reaction

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Antimicrobial activity of rifampicin released from the rifampicin-containing-polyurethane immobilized on the surface with the polyallyamine membrane using photochemical reaction (광화학반응으로 polyallyamine막이 표면에 고정화된 리팜피신-함유 폴리우레탄으로부터 유리되는 리팜피신의 항균 활성에 관한 연구)

  • Jeon, S.M.;Lee, K.B.;Kim, H.J.;Kim, M.N.;Min, B.G.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.05
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    • pp.31-34
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    • 1997
  • A new method for the prevention of foreign body-associated infections by controlled release of antibiotic was developed. The polyurethane (PU) matrix containing rifampicin was immobilized with hydrophilic photoreactive polyallylamine (PPA) containing azidophenyl groups. The rifampicin release characteristics and the long-lasting antimicrobial activities of the new material was compared with rifampicin-containing PU matrix without PPA membrane. The release rate of antibiotic from rifampicin-containing PU with PPA membrane significantly decreased as the thickness of PPA membrane was increased. The PPA-immobilized rifampicin-containing PU discs immersed in the PBS for 47 days had an efficient antimicrobial activity against both S. aureus and S. epidermidis.

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Severe Exogenous Lipoid Pneumonia Following Ingestion of Large Dose Squalene : Successful Treatment with Steroid (다량의 스쿠알렌 복용 후 발생한 중증 지방성 폐렴 -스테로이드 치료로 호전된 1예-)

  • Choi, Hyo Sun;Kwang, Hyon Joo;Chae, Seung Wan;Lim, Si Young;Lim, Seong Yong
    • Tuberculosis and Respiratory Diseases
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    • v.60 no.2
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    • pp.235-238
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    • 2006
  • Exogenous lipoid pneumonia (ELP) is an uncommon condition resulting from aspiration or inhalation of vegetable, animal or mineral oil. It results in foreign body type inflammatory reaction of the lung and can show various clinical presentations from asymptomatic incidental finding to severe pneumonia leading to acute respiratory failure. Although many cases have been reported, severe ELP requiring steroid or whole lung lavage for treatment is rare. We report a case of 51-year old man with esophageal cancer who developed severe ELP following ingestion of large dose shark oil (Squalene) and successfully treated with prednisolone.

The Correction of the Mandibular Defect Using Porous Polyethylene: Case Report (다공성 폴리에틸렌을 이용한 하악골 함몰의 교정: 증례보고)

  • Im, Jae-Hyung;Kim, Su-Gwan;Moon, Seong-Yong;Oh, Ji-Su;Park, Jin-Ju;Jeong, Mi-Ae
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.33 no.4
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    • pp.363-367
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    • 2011
  • Genioplasy with osteotomy is a flexible and useful procedure. However, osteotomy can cause different types of morbidity. Chin augmentation with porous polyethylene ($Medpor^{(R)}$) has become popular in the recent years. Porous polyethylene ($Medpor^{(R)}$) is an excellent biomaterial for reconstructing facial deformities. $Medpor^{(R)}$ has a porous architecture, which prevents capsule formation and decreases the degree of foreign-body reaction. In addition, it can be easily cut with scissors and molded, and it also maintains its shape. We report here on a satisfactory case of chin augmentation with using porous polyethylene ($Medpor^{(R)}$).

Points to consider before the insertion of maxillary implants: the otolaryngologist's perspective

  • Kim, Sung Won;Lee, Il Hwan;Kim, Soo Whan;Kim, Do Hyun
    • Journal of Periodontal and Implant Science
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    • v.49 no.6
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    • pp.346-354
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    • 2019
  • Maxillary implants are inserted in the upward direction, meaning that they oppose gravity, and achieving stable support is difficult if the alveolar bone facing the maxillary sinus is thin. Correspondingly, several sinus-lifting procedures conducted with or without bone graft materials have been used to place implants in the posterior area of the maxilla. Even with these procedures available, it has been reported that in about 5% of cases, complications occurred after implantation, including acute and chronic sinusitis, penetration of the sinus by the implant, implant dislocation, oroantral fistula formation, infection, bone graft dislocation, foreign-body reaction, Schneiderian membrane perforation, and ostium plugging by a dislodged bone graft. This review summarizes common maxillary sinus pathologies related to implants and suggests an appropriate management plan for patients requiring dental implantation.

Restylane Injection into the Vocal Cord of the Patient with Unilateral Vocal Cord Paralysis -A Case Report- (편측 성대마비에서 Restylane을 이용한 성대내 주입치료 1예 -증 례 보 고-)

  • Park, Tae-Joon;Lim, Jae-Yol;Seo, Hyung-Seok;Choi, Hong-Shik
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.15 no.1
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    • pp.43-47
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    • 2004
  • When a person was suffered from vocal cord paralysis or glottic insufficiency, injection materials (e.g Teflon, Bovine collagen, Autologous fat & tendon, Gelfoam) into the vocal cord have been widely used. But each injection material has some disadvantage. We introduce the Restylane which is composed of a hyaluronic acid, artificially producted. It has advantage of rate foreign body reaction, proper endurance, easy to injection. The patient was 55-year-old woman who showed left vacal cord paralysis after pneumonectomy due to aspergillosis, taken the type I thyroplasty and arytenoid adduction. The middle portion of left vocal cord has some atropic mucosal change, slight chink was noted. The restylane injection into vocal cord was done with suspension laryngoscopy under general anesthesia. In the 3 month follow-up after Restylane injection, the quality of voice has been better progressively. We report a case of Restylane injection as a new method for the improvement of quality of voice.

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Ectopic Bone Formation Induced By BMP - Fibrous Collagen Membrane Composite (BMP-교원질 섬유막 복합체에 의한 이소성 골형성)

  • Shin, Hong-In;Suh, Jo-Young
    • Journal of Periodontal and Implant Science
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    • v.26 no.1
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    • pp.68-79
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    • 1996
  • To investigate the efficiency of a fibrous collagen membrane(FCM) composed of bovine skin type I atelocollagen as a carrier for BMP, partially purified bovine BMP/FCM($0.3mg/10{\times}5{\times}1mm$) composites were implanted into the dorsal subcutaneous tissue of rats. FCM alone was also implanted as a control. The implants were harvested at 1, 2, 3, and 10 weeks after implantation, then prepared for routine light microscopic observation. The FCM alone did not induce osteogenesis and revealed no specific foreign body reaction nor was there any definite resorptive evidence for 10 weeks after implantation, while the BMP/FCM composites induced favorable bone formation in a process that resembled an endochondral and direct ossification mode. At 10 weeks, the well formed bone confined to embedded collagen fibers revealed hematopoietic marrow between bony trabeculae without evidence of resorptive or degenerative changes . These findings support the suggestion that BMP may induce undifferentiated mesenchymal cells into either chondroblasts or osteoblasts or both independantly according to the chemico- physical characteristics of the carrier, which develops the endochondral and/or direct bone formation process, and suggest that the FCM may be a favorable carrier for BMP.

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BIOMECHANICAL STUDY OF THE CALVARIAL DEFECTS AFTER IMPLANTATION OF THE TOOTHASH AND PLASTER IN THE RAT (백서에서 치아회분과 석고 매식 후 두개 결손부의 생물물리적 성질에 관한 실험적 연구)

  • Kim, Young-Kyun;Ko, Young-Mu
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.19 no.1
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    • pp.45-54
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    • 1997
  • The purpose of this investigation was to determine the biomechanical property of calvarial defects reconstructed using toothash, plaster and tooth-plaster mixture. Full-thickness bony defects were made on the rat calvaria with size of $10mm{\times}10mm$. Group 1 was filled with toothash only, group 2 : toothash-plaster mixture, and group 3 : plaster only. The defects were allowed to heal for 12 and 20 weeks before killing the animals. Light microscopic examinations vas taken after 12 week after operation. The hardness was evaluated for test of mechanical property. The following results were obtained : 1. In light microscopic examination 12 week after operation, there were no inflammatory and foreign body reaction. Implanted particles were resorbed gradually or united directly with newly formed bone. 2. In hardness test, the hardness of newly formed bone was lower than that of normal bone and there was significant difference(P<0.01). The site of new bone formation has enough hardness to resist the mechanical stress. These results suggest that toothash and plaster are biocompatible and osteoconductive material.

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Utility of the BoneSource® in the Treatment of Craniofacial Bone Defect (두개안면골 결손 환자의 치료에서 Bonesource®의 유용성)

  • Byeon, Jun Hee;Song, Jin Kyung;Yoo, Gyeol
    • Archives of Plastic Surgery
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    • v.32 no.1
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    • pp.24-28
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    • 2005
  • Skull or facial bone defect causes cosmetic and functional problems. On going efforts were taken to reconstruct the craniofacial bone defect with autogenous bone or alloplastic materials. Between 2001 and 2003, we reconstructed 15 cases with small to large craniofacial bone defect using Hydroxyapatite paste($BoneSource^{(R)}$, Leibinger Corp., Dallas, TX, U.S.A) and calvarial bone graft. All patients were followed up by clinical examination and periodic radiographic studies for an average of 1.6 years (range, 6 months to 2 years and 6 months). One complication case was noted with $BoneSource^{(R)}$ exposure. Otherwise, there was no evidence of adverse healing, wound infection, foreign body reaction and seroma collection in other patients. Adequate 3-dimensional aesthetic restoration of calvarial contour was noted in each case. In conclusion, $Bonesource^{(R)}$ is relatively safe and rigid material for craniofacial bone defect and reasonable method for the reconstruction of craniofacial bone defects.

The Clinical Implications of Poly Implant Proth$\grave{e}$se Breast Implants: An Overview

  • Wazir, Umar;Kasem, Abdul;Mokbel, Kefah
    • Archives of Plastic Surgery
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    • v.42 no.1
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    • pp.4-10
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    • 2015
  • Mammary implants marketed by Poly Implant Proth$\grave{e}$se (PIP) were found to contain industrial grade silicone and this caused heightened anxiety and extensive publicity regarding their safety in humans. These implants were used in a large number of patients worldwide for augmentation or breast reconstruction. We reviewed articles identified by searches of Medline, PubMed, Embase, and Google Scholar databases up to May 2014 using the terms: "PIP", "Poly Implant Proth$\grave{e}$se", "breast implants" and "augmentation mammoplasty" "siloxanes" or "silicone". In addition the websites of regulating bodies in Europe, USA, and Australia were searched for reports related to PIP mammary implants. PIP mammary implants are more likely to rupture than other implants and can cause adverse effects in the short to the medium term related to the symptoms of rupture such as pain, lumps in the breast and axilla and anxiety. Based on peer-reviewed published studies we have calculated an overall rupture rate of 14.5% (383/2,635) for PIP implants. However, there is no evidence that PIP implant rupture causes long-term adverse health effects in humans so far. Silicone lymphadenopathy represents a foreign body reaction and should be treated conservatively. The long-term adverse effects usually arise from inappropriate extensive surgery, such as axillary lymph node dissection or extensive resection of breast tissue due to silicone leakage.