Severe Exogenous Lipoid Pneumonia Following Ingestion of Large Dose Squalene : Successful Treatment with Steroid

다량의 스쿠알렌 복용 후 발생한 중증 지방성 폐렴 -스테로이드 치료로 호전된 1예-

  • Choi, Hyo Sun (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Kwang, Hyon Joo (Department of Radiology, Kangbuk Samsung Hospital) ;
  • Chae, Seung Wan (Department of Pathology, Kangbuk Samsung Hospital) ;
  • Lim, Si Young (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine) ;
  • Lim, Seong Yong (Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine)
  • 최효선 (성균관대학교 의과대학 내과학교실, 강북삼성병원 호흡기내과) ;
  • 곽현주 (강북삼성병원 영상의학과) ;
  • 채승완 (강북삼성병원 해부병리과) ;
  • 임시영 (성균관대학교 의과대학 내과학교실, 강북삼성병원 호흡기내과) ;
  • 임성용 (성균관대학교 의과대학 내과학교실, 강북삼성병원 호흡기내과)
  • Received : 2005.11.25
  • Accepted : 2006.01.23
  • Published : 2006.02.28

Abstract

Exogenous lipoid pneumonia (ELP) is an uncommon condition resulting from aspiration or inhalation of vegetable, animal or mineral oil. It results in foreign body type inflammatory reaction of the lung and can show various clinical presentations from asymptomatic incidental finding to severe pneumonia leading to acute respiratory failure. Although many cases have been reported, severe ELP requiring steroid or whole lung lavage for treatment is rare. We report a case of 51-year old man with esophageal cancer who developed severe ELP following ingestion of large dose shark oil (Squalene) and successfully treated with prednisolone.

외인성 지방 흡인에 의한 지방성 폐렴은 대부분 양성의 경과를 취하지만, 본 증례에서처럼 드물게 심한 호흡 부전을 동반할 수도 있으며, 스테로이드 치료에 호전을 보인 1예를 경험하여 이를 보고하는 바이다.

Keywords

References

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