• Journal of Chest Surgery
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• v.42 no.1
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• pp.79-86
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• 2009

Background: Background: Computed tomography (CT) is the main tool for detecting abnormalities of the thoracic aorta, but conventional CT only shows the cross-sectional images. These CT images have some limitations fo accuratly measuring the thoracic aortic diameters at various levels. Multidetector computed tomography (MDCT) overcomes these limitations. We measured the thoracic aortic diameter perpendicular to the loop-shaped thoracic aortic course and this was studied in relation to age, gender, height, weight, the body surface area, the body mass index and the presence of hypertension. Material and Method: Thirty hundred thirty one patients (males: 141 patients and females: 190 patients) who had no abnormalities of the thoracic aorta were investigated using MDCT aortography. They were divided into three age categories: 20~39 years old, 40~59 years old and over age 60. The image was reformed with multiplanar reconstruction and the diameter of the aorta was measured perpendicular to the aortic course at 5 anatomic segments. Level A was the mid-ascending aorta, level B was the distal ascending aorta, level C was the aortic arch, level D was the aortic isthmus and level E was the mid-descending aorta. Result: The mean age was 49.5 years old for males and 54.9 years old for females (p<0.05). The mean diameter of the thoracic aorta at level A was 31.1 mm, that at level B was 30.2 mm, that at level C was 26.5 mm, that at level D was 24.0 mm and that at level E was 22.6 mm. The diameters at all the levels were gradually increased with age. Hypertensive patients had larger diameters than did the non-hypertensive population. There was a positive correlation between the ascending aortic diameter (levels A&B) and height and the body surface area, but there were no statistical differences at the aortic arch (level C) and the descending aorta (levels D&E). There were no statistical differences of the weight and body mass index at all levels. Conclusion: The diameters of the thoracic aortas were directly correlated with gender, age and hypertension. Height and the body surface area were only correlated with the ascending aorta. Weight and the body mass index have no statistical difference at all levels. We measured the age related thoracic aortic diameters and the upper normal limits and we provide this data as reference values for the thoracic aortic diameter in the Korean population.

• Journal of Pharmaceutical Investigation
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• v.34 no.1
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• pp.49-55
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• 2004

To develop a aceclofenac soft capsule, four preparations with various solubilizers were prepared and their dissolution test was carried out. Among four preparations tested, a preparation with ethanolamine was selected as a formula of aceclofenac soft capsule (Clanza $S^{TM}$), since it showed the fastεst dissolution rate. Bioequivalence of aceclofenac tablet, $Airtal^{TM}$ (Dae-Woong Pharmaceutical Co., Ltd.) and aceclofenac soft capsule, Clanza $S^{TM}$ (Korea United Pharmaceutical Co., Ltd.) was evaluated according to the guideline of KA Fourteen normal male volunteers (age 20 - 25 years old) were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After oral administration of one tablet or capsule containing 100 mg of aceclofenac, blood was taken at predetermined time intervals and the concentration of aceclofenac in plasma was determined with an HPLC method under UV detector The pharmacokinetic parameters ($C_{max}$ and $AUC_t$) were calculated and ANOVA was utilized for the statistical analysis of parameters using logarithmetically transformed $AUC_t$, $C_{max}$ and $T_{max}$. The results showed that the differences in $AUC_t$, $C_{max}$ and $T_{max}$ between Aral tablet and Clanza soft capsule were 2.89%, 0.18% and 43.0%, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(15) (e.g. log(0.81) -log(1.23) ad log(0.89) -log(1.4)) fo $AUC_t$ and $C_{max}$, respectively. Thus, the criteria of the KFDA guidelines for the equivalence was satisfied, indicating that Clanza $S^{TM}$ soft capsule is bioequivalent to$Airtal^{TM}$ tablet.

• Archives of design research
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• v.20
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• pp.279-291
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• 1997

The history of modern design begins with the arts and crafts movement(1860). The importance of the movement which decorated the outset gave birth to all the trends of thought which would occur under the circumstances within it, and is deemed that the ideas of the figures who played an active part in the movement might be ceaselessly continued through the works and ideas of their outstanding juniors or purpils as a doctrine of the philosophy of design. Therefore, it might be a prerequisite that the significance and spirit of the movement, and its developing process should be addressed in detail in the first place, but for the limited space of this paper, it was intended to desvribe only the part which can be interpreted in duplicate, linked with post-impressionism. The subject of this thesis is about a theory of art in which both ideas of the movement(1860) and the post-impressionism(1910) are comparatively reviewed. The genre, strictly speaking, is classified into the history of painting, and there is a gap fo about an half century between the issues which are comparatively discussed here. Both the movements began in a same environmental place of England, specially the movement at Milieu in England, and since there is a common point that the representative runners of each movement, William Morries(1834-1896) and Roger Fry(1866-1934), belong to a same race of Engol-Saxon, their ideas coincide with an aesthetic scholar, H. Tanie's aesthetic interpretation method and the more important is, as being elucidated in the comment and aesthetic theory for which Roger Fry gave effort and activity in his later life, that when he read intensively Ruskin's books, $\ulcorner$Modern Painters$\lrcorner$and$\ulcorner$Stones of Venice$\lrcorner$he had solidified his idea of post-impressionism while giving approval and criticism on them. After all, as in a co-painter, Windyham Lewis's reference of 'Roger Fry's Too Late Morris Movement', he, inspired by the actual activities of Morris, played activities similar to that of Morris in which exhibiting and selling some of his decorative art works signed by him and the works of post-impressionism through (1913-1920). Herein, that is wished to add a remark by this author is a point that the author of$\ulcorner$Vision and Design$\lrcorner$, Roger Fry, has not be made a subject of discussion specially in the Korean world of design. So, with this case of a thesis, it's wished that many latent awakened, design persons in korea give efforts to researching into Roger Fry so that their findings could be officially announced in the would. By the way, what is tried to describe in this paper from now on is to analyse and review the origin of post-impressionism which idea was first coined in the art world through the 1st and 2nd exhibitions of 'Manet and Post-impressionism' which were opened each at the Grafton Gallery in 1910 and 1913 by him. And also, it is intended to review it through the art journals and some references by critics of the day in which favorable criticism or severe criticism were ready to comment through the opinions and influences of the coworkers of Roger Fry, say, Clive Bell, Desmond Maccarthy, etc. and of himself as a main axis, on the art ideas of Gauguin, Gogh, Matisse, and Cezanne whose works were the typical ones participated and exhibited in those 1st and 2nd exhibitions.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.16 no.4
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• pp.305-315
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• 1983

A survey was carried out from July to December in 1979 and 1982 for the investigation of oceanographic conditions and phytoplankton in Seogwipo coastal area. Although a peculiar coastal sea water is formed by in flowing of fresh water, this is developed mainly in summer and disappeared or weakened in its strength after November. However, this coastal sea water covers only the surface while in mid and bottom layer open sea water is approached to the coast. Therefore, coastal and open sea water appears simultaneously in narrow sea area. Mean values of nutrient concentrates on surface layer during investigating period were $3.72{\sim}16.34{\mu}g-at/l$ in silicate, $1.98{\sim}5.53{\mu}g-at/l$ in nitrate and $0.34{\sim}0.90{\mu}g-at/l$ in phosphate. These showed slight differences among places but in general coastal side were lower than open sea side. Phosphates which is the lowest in concentrates among nutrients in Seogwipo coastal area shows almost similar value with Jinhae Bay but higher than open sea water around 10 mile south of Seogwipo. In general, seasonal changes of nutrients in investigating period shows a tendency of the lowest in October, increasing in November, and again slight decrease in December. As a phytoplankton fauna, 48 species, 1 variety and 2 breeds of Diatoms, 29 species, 3 varieties and 1 breed fo Dinoflagellates, and 1 species each of Chroococcus and Trichoceratium were found. Monthly predominant species are all neritic: Rhizosolenia sp. and Ceratium sp. in August, Chaetoceros sp., Ceratium sp. and Peridinium sp. in September, Astrionella sp. and Peridinium sp. in October, Astrionella sp., Navicula sp. and Chaetoceros sp. in November Among these, Rhizosolenia alata f. gracillima in August and Astrionella gracillima in November are remarkable predominant.

• Clinical and Experimental Pediatrics
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• v.46 no.12
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• pp.1186-1193
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• 2003

Purpose : Fragile sites are points on chromosomes which tend to break non-randomly when exposed to specific chemical agents or conditions of tissue culture. The chromosomal break induced by the antineoplastic drug, 1-${\beta}$-D-arabinofuranosyl-cytosine(Ara-c), was investigated to study the laboratory conditions in which the incidence of chromosomal break could be enhanced. Besides, the fragile sites induced by Ara-C were investigated and compared to the already known locations of the specific chromosomal alterations observed in specific neoplasms. Methods : T-lymphocytes from theree normal males and three females were cultured for 48 hours. Cells from each individual were exposed to the Ara-C for an additional 24 hours. After the caffeine was added during the last six hours culture, the metaphase chromosomes were prepared following the conventional method. A site was considered fragile if it was found to break two or more per 100 chromosomal breaks in more than four of six individuals tested. Results : Ara-C induced 252.1 chromosomal breaks per 100 mitotic cells and this result was significantly higher than that of the control, which induced 25.2 breaks(P<0.05). The incidence of the chromosomal break by Ara-C was higher, if cultured in the MEM-FA, which has no folic acid, than in the RPMI 1640 which contains enough folic acid(P<0.05). The most common break site by Ara-C was 3p14.2(FRA3B). There were 20 fragile sites induced by Ara-C. Among these 20 fragile sites, seven coincided with the locations of the mapped oncogenes, JUN, SKI, REL, N-MYC, FHIT, MET, ETS-1, and FOS. Conclusion : S phase specific chemotherapeutic agent, Ara-C, induced the expression of the chromosomal fragile sites effectively using the T-lymphocyte in vitro. Some of the fragile sites by Ara-C highly coincided with the oncogenes and neoplasm specific chromosome breakpoints. In this regard, the fragile sites reported here could provide the unknown neoplasm related chromosomal alternation points.

• Journal of Korean Society for Atmospheric Environment
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• v.15 no.2
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• pp.89-100
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• 1999

The rain water samples were collected at Chunchon and Seoul by using wet only automatic sampler from January 1996 through 1997. The daily base rain water samples collected over than 95% rainy events components, $SO_4^{-2}$, $NO_3^-$, $CI^-$, NH_4^+$, $Ca^{2+}$, $Mg^{2+}$, $Na^+$, and $K^+$, by ion chromatography. In 1996, about 77% of sampled rain water showed below pH 5.6 and the 60% of rain water was lower than pH 5.0. The volume weighted average pH was 4.7 at all sites. In 1997, the volume weighted average pH was 4.6 and 4.9 at Seoul and Chunchon, respectively. Among the rain water samples,, 87% and 55% fo samples showed below than pH 5.6 and 5.0, respectively. The pH value of Chunchon was significantly (p＜0.05) lower than Seoul at the rain samples for less than 20mm rainfall. However conductivity of the rain samples were 20.9$\mu$S/cm for 1996 and 27.7$\mu$S/cm for 1997 at Seoul, and 19.1$\mu$S/cm for 1996 and 14.1$\mu$S/cm for 1997 at Chunchon. $H_2SO_4$ and $HNO_3$ contributed 65.9% and 29.6% of free acidity at Seoul, respectively. The ratio of [$NO_3^-$]/[nss-$SO_4^{-2}$] were 0.43 at Seoul and 0.51 at Chunchon for rain samples for less than 20mm rainfall. The annual wet deposition of $CI^-$, $NO_3^-$, $SO_4^{-2}$, $H^+$M, $Na^+$, NH_4^+$, $K^+$, $Mg^{2+}$, and $Ca^{2+}$, respectively, 568.8kg/$ extrm{km}^2$, 1489.3kg/$\textrm{km}^2$, 3184.8kg/$\textrm{km}^2$, 20.9kg/$\textrm{km}^2$, 249.4kg/$\textrm{km}^2$, 1091.2kg/$\textrm{km}^2$, 189.8kg/ $\textrm{km}^2$, 90.2kg/$\textrm{km}^2$ and 702.4kg/$\textrm{km}^2$ at Seoul for 1996; 656.4kg/$\textrm{km}^2$, 2029.7kg/$\textrm{km}^2$, 3280.7kg/$\textrm{km}^2$, 27.2kg /$\textrm{km}^2$, 229.4kg/$\textrm{km}^2$, 1063.9kg/$\textrm{km}^2$, 106.9kg/$\textrm{km}^2$, 78.2kg/$\textrm{km}^2$, 645.3kg/$\textrm{km}^2$ at Seoul for 1997; 116.9kg/ $\textrm{km}^2$, 983.3kg/$\textrm{km}^2$, 1797.0kg/$\textrm{km}^2$, 21.4kg/$\textrm{km}^2$, 83.2kg/$\textrm{km}^2$, 648.1kg/$\textrm{km}^2$, 78.0kg/$\textrm{km}^2$, 22.2kg/$\textrm{km}^2$, 368.8kg/$\textrm{km}^2$ at chunchon for 1996; 100.2kg/$\textrm{km}^2$, 1077.6kg/$\textrm{km}^2$, 1754.0kg/$\textrm{km}^2$, 13.4kg/$\textrm{km}^2$, 146.0kg/$\textrm{km}^2$, 602.3kg/$\textrm{km}^2$, 88.8kg/$\textrm{km}^2$, 16.2kg/$\textrm{km}^2$ and 206.8kg/$\textrm{km}^2$ at chunchon for 1997.

• Proceedings of the KSRS Conference
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• 2006.03a
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• pp.101-104
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• 2006

In the Korean seas, Sea Surface Temperature (SST) and Thermal Fronts (TF) were analyzed temporally and spatially during 8 years from 1993 to 2000 using NOAA/AVHRR MCSST. As the result of EOF method applying SST, the variance of the 1st mode was 97.6%. It is suitable to explain SST conditions in the whole Korean seas. Time coefficients were shown annual variations and spatial distributions were shown the closer to the continent the higher SST variations like as annual amplitudes. The 2nd mode presented higher time coefficients of 1993, 94, and 95 than those of other years. Although the influence is a little, that can explain ElNINO effect to the Korean seas. TF were detected by Sobel Edge Detection Method using gradient of SST. Consequently, TF were divided into 4 fronts; the Subpola. Front (SPF) dividing into the north and south part of the East sea, the Kuroshio Front (KF) in the East China Sea (ESC), the South Sea Coastal Front (SSCF) in the South sea, and the Tidal Front in the West sea. TF located in steep slope of submarine topography. The distributions of 1st mode in SST were bounded in the same place, and these results should be considered to influence of seasonal variations. To discover temporal and spatial variations of TF,SST gradient values were analyzed by EOF. The time coefficients fo the 1st mode (variance : 64.55%) showed distinctive annual variations and SPF, KF, and SSCF was significantly appeared in March. the spatial distributions of the 2nd mode showed contrast distribution, as SPF and SSCF had strong '-' value, where KF had strong '+' value. The time of '+' and '-' value was May and October, respectively. Time coefficients of the 3rd mode had 2 peaks per year and showed definite seasonal variations. SPF represented striking '+' value which time was March and October That was result reflected time of the 1st and 2nd mode. We can suggest specific temporal and spatial variations of TF using EOF.

• The Journal of the Petrological Society of Korea
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• v.14 no.2 s.40
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• pp.116-126
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• 2005

The Precambrian quartzite and calc-schist layers experienced multi-1310ing events are distributed along the two kinds of U-shaped 1310 (Fold I and II) with $N10^{\circ}E-directed$ fo1d axis in Wollong-myeon, Gwangtan-myeon, Jori-myeon of Paju city, the northeastern part of Gyeonggido. Occurrence of 10 layers of quartzite and 4 layers of calc-schist is not clear whether quartzite and schist layers were deposited sequentially each other or one to two layers of quartzite and schist were distributed repeatedly by isoclinal folding and thrusting, because of lack of sedimentary structures. In this paper, we tried to clarify the correlative relationship among the quartzite beds which are distributed along the U-shaped folds using geochemical tools such as rare earth element (REE) patterns and Nd isotope ratio. Quartzites have characteristics of LREE-flattened, HREE- slightly depleted patterns. They also show Ce negative anomaly whereas there are no Eu anomalies. As a result, quartzite beds occurred along the bilateral sides of fold axis show very similar REE patterns from outer side to inner side of 1314. The Nd model age of quartzite layers shows a trend that the inner part of fold is younger than the outer part of it. Such geochemical characteristics suggest that bilateral quartzite beds occurred along the fold axis were derived from the cogenetic source materials. The REE patterns and trace element geochemistry of mica schist intercalated within quartzite indicate that the quartzite and mica schist may be derived from different source materials. Our results suggest that REE and Nd isotope geochemistries may be very useful in clarifying the relationship of sedimentary deposits which do not show stratigraphical and structural connections in the field.

• Journal of Technologic Dentistry
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• v.31 no.3
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• pp.35-45
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• 2009

This survey study was conducted on dental technician school students in April 2008 to investigate the effects of smoking on oral health. 110 male and 39 female students were surveyed and cross analysis was performed to examine the relationship between oral health status and smoking-related and oral health maintenance characteristics of smoking and non-smoking group. T-test and one-way ANAVA was used to analyze the average difference verification of two independent samples(smoking group and non-smoking group) and followings are the results. In general characteristics, 74 male students(74.7%) and 25 female(25.3%) students smoked and the percentage of male students were higher in smoking group. Regarding class grade, 2nd-year students(37 students, 37.4%) and 1st-year students(18 students, 36.0%) took the highest percentage of smoking and non-smoking group, respectively. Concerning the experience of drinking, smoking group consumed more alcoholic beverages(94 students, 94.9%) With respect to the frequency of between-meal consumption, respondents who eat between-meal once or twice smoked more. Respecting preferences of sweet food, respondents who enjoyed sweet food smoked more. Concerning smoking characteristics, many of smoking group had been smoked fo a long time(two to five years) and it was worrisome. About the amounts of smoking, 50 respondents(52.6%) of smoking group smoked 20 cigarettes a day with the highest proportion. With regard to the awareness of harmfulness, 70 respondents(70.7%) considered smoking as very harmful and showed that smoking group were aware of its harmfulness but it was habitualized. Respecting smokers in family members, father was more common as smokers(58 respondents, 58.6%) in family and showed that the influence of father. Main reasons of poor periodontal health were alchoholic consumption, smoking, and oral parafunctional habit(57 respondents, 56.7%) in smoking group and neglect of oral hygiene(21 respondents, 42.0%) in non-smoking group. With regard to the scaling, 80 respondents of smoking group(80.8%) didn't received scaling and showed that more oral health education was required. Regarding the periodontal status, non-smoking group was $1.26{\pm}0.44$, respondents who received scaling was $1.43{\pm}0.50$, respondents who regularly floss was $1.50{\pm}0.52$, respondents who brush more than three times a day was $1.38{\pm}0.49$ and had better periodontal health. Bleeding during tooth brushing was more frequent in smoking group ($1.51{\pm}0.70$). Regarding mouth order, non-smoking group was $2.34{\pm}0.62$, after scaling was $2.02{\pm}0.76$, patients who regularly floss was $1.50{\pm}0.52$, patients who brush more than three times a day was $1.81{\pm}0.87$. Concerning the experience of dental caries treatment, smoking group was $1.20{\pm}0.40$, patients who do not floss was $1.30{\pm}0.46$, patients who brush once a day was $1.29{\pm}0.45$. With regard to dental prosthesis, non-smoking group was $3.78{\pm}1.62$, patients who received scaling was $1.43{\pm}0.50$, patients who regularly floss was $1.40{\pm}0.51$, patients who brush more than three times a day was $1.24{\pm}0.43$. From these results, oral health education and smoking has correlation and more oral health education needs to be carried out to educate students with non-health related majors about harmfulness of smoking on oral health. Also more study are required.

• Journal of Korean Ophthalmic Optics Society
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• v.20 no.3
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• pp.377-384
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• 2015

Purpose: On this study, we measured and compared the dynamic stereoacuity by two-rods test (Howard-Dolman Test) and three-rods test. And we analyzed the correlation between PD and refractive error with dynamic stereoacuity. Methods: Dynamic stereoacuity of two-rods test and three-rods test at 2.5 m distance for 93 adults 93 (50 males, 43 females), mean age of $21.27{\pm}2.32$ (19~32) years old, were measured 5 times for two tests. Results: The mean of dynamic stereoacuity measured by two-rods test and three-rods test were $29.91{\pm}23.03sec$ of arc and $23.75{\pm}21.65sec$ of arc for total subjects, respectively. The mean of male and female were $36{\pm}22.38sec$ of arc and $22.28{\pm}23.79$, respectively. Three-rods test showed better dynamic stereoacuity than two-rods test, but there was no statistically significant difference (p>0.05). For the average standard deviation of PD between 60.63 mm~66.19 mm, dynamic stereoacuity fo two-rod test and three-rod test were $31.48{\pm}24.87sec$ of arc and $31.48{\pm}24.87sec$ of arc, respectively. The results showed statistically significant difference (p<0.05), but the relationship between dynamic stereoacuity and PD was not great. Comparison between two tests on the basis of refractive error, dynamic stereoacuity by three-rods test was better than by two-rods test with no significant difference between both tests (p>0.05) and there was little correlation between refractive error and two dynamic stereoacuity. Conclusions: Three-rods test showing lower stereoacuity than two-rods tests could measure the lower minimum threshold of dynamic stereoacuity. It was found that both tests can be applied to dynamic stereoacuity test as a standard test, and PD and refractive error was found that little effect upon the dynamic stereoacuity. PD and refractive error was found that little effect upon the dynamic stereoacuity.