• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.5
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• pp.1127-1134
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• 2007

The study was designed to investigate the mechanism of Patholoobi Caulis freeze dried powder (PCF) on the regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats and cytokines production ($IL-1{\beta}$, $TNF-{\alpha}$, IL-10, $TGF-{\beta}$) in cerebral ischemic rats. The results in normal rats were as follows ; Increase of PCF-induced rCBF was significantly inhibited by pretreatment with methylene blue (10 ${\mu}g/kg$, I.p.), an inhibitor of guanylate cyclase, and was inhibited by indomethacin (1 mg/kg, i.p.), an inhibitor of cyclooxygenase. Increase of PCF-induced MABP was decreased by pretreatment with methylene blue, but was increased by indomethacin. These results suggested that the mechanism of action PCF was mediated by cyclic 3',5'-guanosine monophosphate. The results in cerebral ischemic rats were as follows ; In cytokine production in serum from femoral arterial blood 1 hr after middle cerebral arterial occlusion, PCF (10 mg/kg. i.p.) significantly decreased $IL-1{\beta}$ and $TNF-{\alpha}$ production, and increased IL-10 production compared with control group. In cytokine production in serum from femoral arterial blood 1 hr 1 hr after reperfusion, PCF (10 mg/kg, i.p.) significantly decreased $IL-1{\beta}$ production, and incresed IL-10 production compared with control group. These results suggested that PCF was significantly and stably increased regional cerebral blood flow by inhibiting $IL-1{\beta}$ production, and by accelerating IL-10 production.

• Proceedings of the Safety Management and Science Conference
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• 2007.11a
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• pp.9-19
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• 2007

This study deals with the improvement of production process on a flow production system with the consideration of six sigma. We analyze the production process and survey the important factors of improvement of productivity. Using a six sigma, we find strategic point and suggest a reformation of production process. We applied a simulation technique to simulate the production line proposed by the result of the Six sigma. With the result of the simulation, this study analyzes the propriety of production line and proposes the alternatives of new production process.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.696-701
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• 2018

The nitrogen oxides generated during combustion reactions have a great influence on the generation of acid rain and fine dust. As an NOx reduction method, exhaust gas recirculation combustion using Coanda nozzles capable of recirculating a large amount of exhaust gas with a small amount of air has recently been utilized. In this study, for the burner outlet with dual end opening, the use of a recirculation burner was investigated for the distribution of the pressure, streamline, temperature, combustion reaction rate and nitrogen oxides using computational fluid analysis. The gas mixed with the combustion air and the recirculated exhaust gas flow in the tangential direction of the circular cylinder burner, so that there is a region with low pressure in the vicinity of the fuel nozzle exit. As a result, a reverse flow is formed in the central portion of the burner near the center of the circular cylinder burner and the exhaust gas is discharged to the outside region of the circular cylinder burner. The combustion reaction occurs on the right side of the burner and the temperature and NOx distribution are relatively higher than those on the left side of the burner. It was found that the average NOx production decreased from an air flow ratio of 1.0 to 1.5. When the air flow ratio is 1.8, the NOx production increases abruptly. It is considered that the NOx production reaction increases exponentially with temperature when the air ratio is more than 1.5 and the NOx production reaction rate increases rapidly on the right-hand side of the burner.

• Journal of Embryo Transfer
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• v.23 no.4
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• pp.275-281
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• 2008

The ability to preselect the sex of piglets is advantageous in the pig industry. The objective of this study was to examine the feasibility of using intracytoplasmic sperm injection (ICSI) with sorted spermatozoa to produce piglets with a preselected sex. Pig embryos were produced by ICSI of frozen X- and Y-sperm that had been separated by flow cytometry. The developmental competence of the embryos was investigated in vitro and in vivo. The populations of X- and Y-spermatozoa were 52.7% and 47.3%, respectively in our samples. The in vitro development of ICSI embryos was enhanced by longer of in vitro maturation of oocytes ($44{\sim}48\;h$ vs. $40{\sim}43\;h$). Their cleavage ($65{\sim}70%$) and blastocyst formation ($9{\sim}12%$) rates were not significantly different between male and female ICSI embryos, or between sorted and unsorted sperm-derived embryos. One pregnancy was established in a recipient that was transferred with 110 female ICSI embryos, but the pregnancy was terminated on Day 89 of gestation. Our results suggest that the separation X- and Y-spermatozoa by flow cytometric sorting can be a useful tool in combination with ICSI for the production of pig embryos and piglets of preselected sex.

• Transactions of the Korean hydrogen and new energy society
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• v.14 no.1
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• pp.61-68
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• 2003

This paper presents the methodology to analyze flow duration characteristics and performance prediction technique for small hydro power(SHP) Plants and its application. The flow duration curve can be decided by using monthly rainfall data at the most of the SHP sites with no useful hydrological data. It was proved that the monthly rainfall data can be characterized by using the cumulative density function of Weibull distribution and Thiessen method were adopted to decide flow duration curve at SHP plants. And, the performance prediction technique has been studied and development. One SHP plant was selected and performance characteristics was analyzed by using the developed technique, Primary design specfications such as design flowrate, plant capacity, operational rate and annual electricity production for the SHP plant were estimated, It was found that the methodology developed in this study can be a useful tool to predict the performance of SHP plants and candidate sites in Korea.

• Journal of the Korean institute of surface engineering
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• v.29 no.6
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• pp.695-702
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• 1996

Plasma spraying process was employed to produce HA coating on Ti6A14V alloy for the development of a dental implant. The goal of this research was to find optimum spraying conditions for HA coating on Ti6Al4V. This study was thus designed carefully to evaluate how spraying parameters affect various physical properties of a HA coating layer, such as phase composition and bond strength. In plasma spraying, spraying parameters such as hydrogen flow rates and spraying distances were varied systematically to change the degree of the melting of starting HA powder in plasma jet. It was revealed that the deposition efficiency increased with increasing a hydrogen flow rate, and the bond strength between the HA-coated layer and Ti-alloy substrate increased with hydrogen flow rate, but decreased with spraying distance. Therefore, the hydrogen flow rate and the spraying distance should be carefully controlled to obtain the reasonable bond strength simultaneously.

• Journal of Korean Society for Atmospheric Environment
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• v.26 no.6
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• pp.624-632
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• 2010

Perfluorocarbons (PFCs) are widely used in semiconductor industry. These gases need to be removed efficiently because of their strong absorption of infrared radiation and long atmospheric lifetimes which cause the global warming effect. To destruct $CF_4$, a waterjet gliding arc plasma was designed and manufactured. The highest $CF_4$ destruction showed at waterjet plasma case, compared to plasma discharge only or water scrubber only, respectively. In addition, it could be known that the $CF_4$ destruction should be associated with the electron and OH radicals. The operating conditions such as waterjet flow rate, initial $CF_4$ concentration, total gas flow rate, specific energy input were investigated experimentally using a plasma waterjet scrubber. Through the parametric studies, the highest $CF_4$ destruction of 94.5% was achieved at 0.2% $CF_4$, 2.1 kJ/L SEI, 20 L/min total gas flow rate and 18.5 mL/min waterjet flow rate.

• Fisheries and Aquatic Sciences
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• v.7 no.4
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• pp.204-214
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• 2004

The effect of wind. stresses on the flow and water quality has been examined, particularly focused on the environment of oyster farms in Gamak Bay, by a two dimensional numerical model. In autumn (wind: $45.0^{\circ}$, 4.3 m/s), the overall flow turned out to be stronger than any other seasons and in addition, a pair of anticlockwise and clockwise vortices has been created at the northwest of the bay. Consequently, the wind in autumn seemed efficient not only for growing oyster but also for reducing the water pollution as the flow becomes much more active. In summer an anoxic condition appeared around the northwest of the bay where the flow is stagnant. According to a field survey, the majority of oyster farms tended to be densely distributed around the areas where DO concentration is high. Furthermore, oyster farms with a high production (over 1,300 kg per hanging string of 100 m) were distributed along with approximately 4 of Ch-a concentration. This suggests that oyster production is closely related to the concentration of DO or Ch-a.

• Safety and Health at Work
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• v.8 no.3
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• pp.250-257
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• 2017

Background: Tasks involved in traditional charcoal production expose workers to various levels of charcoal dust and wood smoke. This study aimed to identify specific tasks influencing lung function and respiratory symptoms. Methods: Interviews, direct observation, and task/symptom checklists were used to collect data from 50 charcoal-production workers on 3 nonwork days followed by 11 workdays. The peak expiratory flow rate (PEFR) was measured four times per day. Results: The PEFR was reduced and the prevalence of respiratory symptoms increased over the first 6-7 workdays. The PEFR increased until evening on nonwork days but not on workdays. Loading the kiln and collecting charcoal from within the kiln markedly reduced the PEFR and increased the odds of respiratory symptoms. Conclusion: Tasks involving entry into the kiln were strongly associated with a short-term drop in the PEFR and the occurrence of respiratory symptoms, suggesting a need for the use of protective equipment and/or the operation of an effective kiln ventilation system.

• IE interfaces
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• v.12 no.3
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• pp.395-400
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• 1999

Shipbuilding process is composed of hull construction, in which the structural body of a ship is formed, and outfitting, in which all the non-structural parts such as pipes, derricks, engines, machinery, electrical cable, etc. are manufactured, added and assembled. Hull construction can be classified into parts fabrication, block assembly and hull erection. Among them, the parts fabrication is the first manufacturing stage that produces components or zones needed for block assembly and hull construction. More specifically, the parts fabrication is performed through machining processes including marking, cutting, pressing, and/or forming. When material is entering into the parts fabrication stage, it is important for achieving the total efficiency of production to select one of production division, so-called 'bay,' as well as machine tools on which the part is fabricated. In this paper, given production quantities of parts in the fabrication stage, the problem is to optimally select machine tools and production division, such that the total flow-time is minimized as well as the workload among machines is balanced. Specifically, three mathematical models for flow-time minimization, load balance, and simultaneously considering both objectives, and a numerical example are analyzed and presented.