• Asian Pacific Journal of Cancer Prevention
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• v.14 no.9
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• pp.5341-5344
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• 2013

Objectives: To explore the relationships between age, cytogenetic subgroups, molecular markers, and cells with leukemic aberrant immunophenotype in patients with acute myeloid leukemia (AML). Methods: In this study, we evaluated the correlations between age, cytogenetic subgroups (normal, balanced and unbalance karyotype), molecular mutations (NPM1, FLT3-ITD, and CEBPA mutations) and marrow leukemia cells (LC) identified by flow cytometry in 256 patients with de novo AML. Results: From age group 10-19 years to age group ${\geq}60$ years, the percentage of LC decreased from $67.0{\pm}18.4%$ to $49.0{\pm}25.1%$ (F=2.353, P=0.041). LC percentage was higher in patients with balanced karyotypes ($65.7{\pm}22.4%$), than those with unbalanced karyotypes ($46.0{\pm}26.6%$) (u=3.444, P=0.001) or a normal karyotype ($49.9{\pm}22.1%$) (u=5.093, P<0.001). Patients with FLT3-ITD ($64.3{\pm}19.5%$) had higher LC percentages compared with those without ($54.2{\pm}24.3%$) (u=2.794, P=0.007). Conclusions: Associations between age, cytogenetics, molecular markers, and marrow leukemia cells may offer beneficial information to understand the biology and pathogenesis of AML.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.11 no.1
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• pp.300-318
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• 1998

Background : The vasoreactivity of cerebral artery is currently the subject of increasing interest. Transcranial Doppler Sonography(TCD) is an accurate method of monitoring the blood flow velocities of the cerebral artery. We wished to assess the vasoreactivity between age-matched normal and cerebral infarction group. Method : We performed TCD findings in 40 normals and 20 cb-inf. subjects who arrived at hospital during 48 hours after attack. The former were devided into twenties normal group and fifties normal group. Result : 1. Fibrinogen levels showed significant changes between age-matched normal and cb-inf. group. 2. $V^{MEAN}$ of the both side Carotid Siphon during rest state increased significantly in cb-inf. group as compared with the age-matched normal group. 3. $V^{MEAN}and\;V^{MAX}$ of the both side carotid siphon during breath-hold state increased significantly in cb-inf. group as compared with the age-matched normal group. 4. Vasoreactivity of cerebral artery increased significantly in cb-inf. group as compared with the age-matched normal group. 5. $V^{MEAN}and\;V^{MAX}$ of the both side Radial artery during heat-stimuration state increased significantly in cb-inf. group as compared with the age-matched normal group. 6. Vasoreactivity of Radial artery increased significantly in cb-inf. group as compared with the age-matched normal group.

• Journal of Korean society of Dental Hygiene
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• v.15 no.2
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• pp.189-196
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• 2015

Objectives: The purpose of the study is to investigate the relationship between saliva factors and oral hygiene factors in adults. Methods: The subjects were 112 adults from April 1 to June 15, 2014. The selected salivary factors included stimulated/unstimulated salivary flow rates, salivary buffering capacity and pH, and the selected oral hygiene factors included halitosis, wet weight of tongue plaque and oral humidity in dorsum and inferior surface of tongue. Results: There were significant differences in stimulated/unstimulated salivary flow rates, oral malodor and wet weight of tongue plaque. There were significant differences according to age in stimulated/unstimulated salivary flow rates, salivary buffering capacity and wet weight of tongue plaque. Age had a negative correlation with salivary buffering capacity and had a positive correlation with wet weight of tongue plaque. Unstimulated salivary flow rate had a positive correlation with stimulated salivary flow rate, and stimulated salivary flow rate was positively correlated with oral humidity of inferior surface of tongue, salivary buffering capacity and halitosis. Oral humidity of inferior surface of tongue had a positive correlation with salivary buffering rate, pH and halitosis. Salivary buffering capacity was positively correlated with pH, and pH was negatively correlated with halitosis. Conclusions: The salivary factors were linked to the oral hygiene. As there may be great changes in salivary flow rate and oral hygiene due to various factors, the salivary factors seem to be one of the major factors to ensure oral hygiene and to promote oral health.

• Proceedings of the Korea Concrete Institute Conference
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• 2002.05a
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• pp.311-316
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• 2002

The following results are achieved from a mortar flow test depending on stainless steel slag fineness, rate of replacement, and a research on material age compressive strength, strength activity index. 1. Flow is proportional to the stainless steel slag fineness. 2. Mixing stainless steel slag decreases compressive strength 3. Material age compressive strength has the maximum value when stainless steel slag fineness is 6000$cm^2$/g. 4. Material age 7day strength activity index satisfies KSCE 95-01 at all conditions except the case of fineness 8000$cm^2$/gㆍstainless steel slag rate of replacement 30%. 5. Material age 28day strength activity index satisfies KSCE 95-01 in case of stainless steel slag fineness 4000$cm^2$/gㆍrate of replacement 10%, fineness 6000$cm^2$/gㆍ10%, or 20%.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2002.05a
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• pp.69-74
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• 2002

The following results are achieved from a mortar flow test depending on stainless steel slag fineness, replacement ratio, and a research on material age compressive strength, strength activity index. 1. Flow is proportional to the stainless steel slag fineness within the limits of 4000~8000$\textrm{cm}^2$/g, but in the case of fineness 20000$\textrm{cm}^2$/g flow decreases at all conditions except the case of replacement ratio 10%. 2. As stainless steel slag replacement ratio increases, Mortar of flow somewhat decreases. 3. As stainless steel slag blends, compressive strength decreases, but in proportion to the increase of age, compressive strength increases. 4. As stainless steel slag replacement ratio, compressive strength decreases. 5. In the case of stainless steel slag fineness 6000$\textrm{cm}^2$/g and 20.000$\textrm{cm}^2$/g, compressive strength of revelation ratio has the maximum value when it's replacement ratio is 10%.

• Korean Journal of Radiology
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• v.22 no.7
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• pp.1194-1202
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• 2021

Objective: To investigate the age-dependent changes in regional cerebral blood flow (CBF) in healthy adults by fitting mathematical models to imaging data. Materials and Methods: In this prospective study, 90 healthy adults underwent pseudo-continuous arterial spin labeling imaging of the brain. Regional CBF values were extracted from the arterial spin labeling images of each subject. Multivariable regression with the Akaike information criterion, link test, and F test (Ramsey's regression equation specification error test) was performed for 7 models in every brain region to determine the best mathematical model for fitting the relationship between CBF and age. Results: Of all 87 brain regions, 68 brain regions were best fitted by cubic models, 9 brain regions were best fitted by quadratic models, and 10 brain regions were best fitted by linear models. In most brain regions (global gray matter and the other 65 brain regions), CBF decreased nonlinearly with aging, and the rate of CBF reduction decreased with aging, gradually approaching 0 after approximately 60. CBF in some regions of the frontal, parietal, and occipital lobes increased nonlinearly with aging before age 30, approximately, and decreased nonlinearly with aging for the rest of life. Conclusion: In adults, the age-related perfusion patterns in most brain regions were best fitted by the cubic models, and age-dependent CBF changes were nonlinear.

• Tuberculosis and Respiratory Diseases
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• v.45 no.5
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• pp.1000-1011
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• 1998

Background: For the diagnosis or evaluation of airway obstruction in bronchial asthma and chronic obstructive lung disorders, various parameters derived from the forced expiratory volume curve and maximal expiratory flow volume curve have been used. Recently the peak expiratory flow(PEF) measured by the peak flow meter is widely used because of its simplicity and convenience. But there were still no data of the predicted normal values measured by the peak flow meter in Korea. This study was to obtain the predicted normal value of PEF and to know the accuracy of this value to predict $FEV_1$. Method: The measurements of PEF by the MiniWright peak flow meter and several parameters derived from the forced expiratory volume and maximal expiratory flow volume curves by the Microspiro HI 501(Chest Co.) were done in 129 men and 125 women without previous history of the respiratory diseases. The predicted normal values of parameters according to the age and the height were obtained, and the regression equation of $FEV_1$ by PEF was calculated. Results: The predicted normal values of PEF(L/min) were -2.45$\times$Age(year) +1.36 $\times$ Height(cm)+427 in men, and -0.96 $\times$ Age (year) + 2.01 $\times$ Height (cm) + 129 in women. FEFmax derived from the maximal expiratory flow volume curve was less than by 125 L/min in men and 118 L/min in women respectively compared to PEF. $FEV_1$(ml) predicted by PEF was 5.98 $\times$ PEF(L/min) + 303 in men, and 4.61 $\times$ PEF(L/min) + 291 in women respectively. Conclusion : The predicted normal value of PEF measured by the peak flow meter was calculated and it could be used as a standard value of PEF while taking care of patients with airway obstruction. $FEV_1$, the gold standard of ventilatory function, could be predicted by PEF to a certain extent.

• Korean Journal of Childcare and Education
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• v.18 no.6
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• pp.37-57
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• 2022

Objective: The purpose of this study was to investigate whether parent's play participation and children's friendly play initiative affect children's executive function through children's play flow. Methods: The survey was conducted on 376 children between the age of 3 and 5 their parents in Daegu city and Gyeonsang province. Data were collected through the questionnaires and analyzed using descriptive statistics, independent sample t-test, one-way ANOVA, Pearson correlation analysis, and path analysis with SPSS 25.0 and AMOS 23.0 programs. Results: The major results were as follows. First, There were significant differences in parent's play participation, children's friendly play initiative, children's play flow, and executive function according to the children's age and family income. Second, parent's play participation and children's friendly play initiative indirectly affected children's executive function through children's play flow. Conclusion/Implications: This study highlights how children's play affects executive function. Also, the findings of this study will contribute to designing various programs that can promote parent's play participation, children's friendly play initiative, and play flow, which affects the children's executive function.

• The Journal of Korean Physical Therapy
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• v.22 no.5
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• pp.49-56
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• 2010

Purpose: The aim of this study was to evaluate a possible role for cranial artery velocity in cervicogenic headache. Methods: We studied 13 patients with cervicogenic headaches (M=9, F=4, age=$24.50{\pm}3.50\;y$) these were compared to 20 normal subjects (M=10, F=10, age=$23.30{\pm}2.90\;y$). Cervicogenic headache patients were divided into two groups (a myofascial relaxation group, a placebo group). Pain levels were measured using a visual analog scale (VAS). Transcranial Doppler (TCD) ultrasound recordings were used to measure blood flow velocity in the cranial artery. Results: Cervicogenic headache patients exhibited a significantly lower blood flow velocity in the middle cerebral artery. The patients who received an intervention had a significantly higher blood flow velocity in the left middle cerebral artery, right vertebral artery and basilar artery. Compared to the placebo group, the myofascial relaxation group exhibited a significantly decreased level of pain. Conclusion: Cervicogenic headache is pain referred to the head from a source in the cervical spine. Manual therapy affect to cervical spine and soft tissue as well as the passage of these vessels and nerves to recover because it is thought to be able to help.

• Journal of Korean Clinical Health Science
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• v.10 no.1
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• pp.1569-1577
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• 2022

Purpose: This study was conducted to investigate academic self-efficacy, metacognition and major satisfaction which influence learning flow in nursing students. Method: The subjects of this study were 239 nursing students in D college. Structured questionnaire was self-administered from May 3 to 30, 2021. The date was analyzed by t-test, ANOVA, Pearson'correlation coefficients, stepwise and multiple regression using SPSS/WIN 22.0. program. Results: In academic self-efficacy, there were significant differences in age. In metacognition, there were significant differences in age, school record. There was a statistically positive correlation between learning flow and academic self-efficacy(r=.211, p=.001), metacognition(r=.357, p<.001), major satisfaction(r=.281, p<.001). The factors influencing learning flow were metacognition(t=.682, p<.001), major satisfaction(t=2.147, p=.023)Multiple regression analysis description is 61.2%. Conclusion: To improve the learning outcomes for nursing students, it is necessary to develop teaching program and curriculum for increasing, metacognition and major satisfaction.