• 대한약침학회지
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• 제20권4호
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• pp.274-279
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• 2017

Objective: SanYangSam and SanYangSanSam are traditional Korea-medical herbs that are grown from Panax ginseng C.A. Meyer. In our previous studies, we found that the functional compounds in SanYangSam and SanYangSanSam were different and depended on the type and the cultivation environment of ginseng. This study aimed to profile the functional constituents in SanYangSam and SanYangSanSam. Methods: To profile the functional aspects of the many compounds that have therapeutic activities in SanYangSam and SanYangSanSam extracts, we used liquid chromatography tandem mass spectrometry and quadrupole orthogonal acceleration time-of-flight mass spectrometry. Results: A total of four major compounds were detected; two of which were the natural flavonoids kaempferol and quercetin. Among others, two polyacetylene compounds, including panaxydol and panaxynol, were detected. Conclusion: In this study, we found that panaxydol, one of the polyacetylene constituents of ginseng, is a candidate anti-cancer agent in SanYangSam and SanYangSanSam pharmacopuncture. In addition, we found that the panaxydol levels in the SanYangSanSam extract were over 30 times those in the SanYangSam extract.

• 한국미생물·생명공학회지
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• 제48권2호
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• pp.138-147
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• 2020

Various microorganisms play important roles in food fermentation, food spoilage, and agriculture. In this study, the biotype of 54 yeast and bacterial strains having high potential for utilization in food and agriculture, including Candida spp., Lactobacillus spp., and Acetobacter spp., were characterized by matrix-assisted laser desorption/ionization time-of flight mass spectrometry (MALDI-TOF MS). This characterization using a fast and robust method provides much-needed information on the selected microorganisms and will facilitate effective usage of these strains in various applications. Importantly, the unique protein profile of each microbial species obtained from this study was used to create a database of fingerprints from these species. The database was validated using microbial strains of the same species by comparing the mass spectra with the created database through pattern matching. The created reference database provides crucial information and is useful for further utilization of a large number of valuable microorganisms relevant to food and agriculture.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2005년도 추계학술대회논문집
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• pp.227-230
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• 2005

This paper describes the problems in measuring and evaluating the aviation noises and the differences on the noise characteristics between fighter and civil aircraft. From a standpoint of the duration time for aviation noise and the dynamic characteristics related with the sampling time, the measured values for landing and taking-off noises from the fighter are presented and explained in comparison with those from the civil aircraft. And also the aviation noises by the fighter and civil aircraft are evaluated by equivalent sound level and WECPNL, respectively. From the obtained results, it is recommended that the duration time and dynamic characteristics be deeply considered in evaluating and measuring the aviation noises, since they have a great influence on the final assessment results. As the number of flight is not sufficient and the noise source is strong impulse type, moreover, the aviation noise should be assessed by WECPNL.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2008년 영문 학술대회
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• pp.810-812
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• 2008

Previously study on structural design of the main wing of the twenty-seat class WIG(Wing in Ground Effect) craft. In the final design, three spars construction was selected for safety in the critical flight load, and the Carbon-Epoxy material was selected for lightness and structural stability. In this study, the forced vibration analysis was performed on the composite main wing structure of the twenty-seat class WIG craft with two-stroke pusher type reciprocating engine. The vibration analysis based on the finite element method was performed using a commercial FEM code, MSC/NASTRAN. Excitations for the frequency response analysis were assumed as the H-mode(horizontal mode), the V-mode(vertical mode) and the X-mode(twisted mode) which are typical main vibration modes of engine. And excitations for the transient response analysis were assumed as the L-mode(longitudinal mode) with the oscillating propeller thrust which occurs in operation. According to the result of forced vibration analysis, structural design was modified to reduce the vibrations.

• Journal of Microbiology and Biotechnology
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• 제29권6호
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• pp.887-896
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• 2019

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)-based pathogen identification relies on the ribosomal protein spectra provided in the proprietary database. Although these mass spectra can discern various pathogens at species level, the spectra-based method still has limitations in identifying closely-related microbial species. In this study, to overcome the limits of the current MALDI-TOF MS identification method using ribosomal protein spectra, we applied MALDI-TOF MS of low-mass profiling to the identification of two genetically related Bacillus species, the food-borne pathogen Bacillus cereus, and the insect pathogen Bacillus thuringiensis. The mass spectra of small molecules from 17 type strains of two bacilli were compared to the morphological, biochemical, and genetic identification methods of pathogens. The specific mass peaks in the low-mass range (m/z 500-3,000) successfully identified various closely-related strains belonging to these two reference species. The intensity profiles of the MALDI-TOF mass spectra clearly revealed the differences between the two genetically-related species at strain level. We suggest that small molecules with low molecular weight, 714.2 and 906.5 m/z can be potential mass biomarkers used for reliable identification of B. cereus and B. thuringiensis.

• 항공우주시스템공학회지
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• 제15권1호
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• pp.40-46
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• 2021

본 연구에서는 재난치안무인기 MC-1,2,3 대비 임무능력이 대폭 향상된 임무확장형 무인기 후보인 틸트로터 무인기의 공력형상설계와 성능향상을 위한 연구를 수행하였다. 기존 운영 중인 TR60 틸트로터 무인기의 형상을 근간으로 성능향상을 위하여 동체 및 꼬리날개 형상을 개선하고 나셀에 확장날개를 장착한 새로운 TR5X 개념형상을 설계하고 전산유체해석을 통해 기존 TR60과 공력성능을 비교하였다. 또한 TR5X 전기체 공력데이터를 구축하고 전기체 비행성능해석을 수행하여 목표로 설정된 주요 성능요구도가 만족됨을 확인하였다.

• Mass Spectrometry Letters
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• 제12권2호
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• pp.47-52
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• 2021

Evaluating the impurity concentrations in semiconductor thin films using time of flight secondary ion mass spectrometry (ToF-SIMS) is an effective technique. The mass interference between isotopes and matrix element in data interpretation makes the process complex. In this study, we have investigated the doping concentration of phosphorus in, phosphorus doped silicon thin film on glass using ToF-SIMS in the dynamic mode of operation. To overcome the mass interference between phosphorus and silicon isotopes, the quantitative analysis of counts to concentration conversion was done following two routes, standard relative sensitivity factor (RSF) and SIMetric software estimation. Phosphorus doped silicon thin film of 180 nm was grown on glass substrate using hot wire chemical vapor deposition technique for possible applications in optoelectronic devices. Using ToF-SIMS, the phosphorus-31 isotopes were detected in the range of 10¹~10⁴ counts. The silicon isotopes matrix element was measured from p-type silicon wafer from a separate measurement to avoid mass interference. For the both procedures, the phosphorus concentration versus depth profiles were plotted which agree with a percent difference of about 3% at 100 nm depth. The concentration of phosphorus in silicon was determined in the range of 10¹⁹~10²¹ atoms/cm³. The technique will be useful for estimating distributions of various dopants in the silicon thin film grown on glass using ToF-SIMS overcoming the mass interference between isotopes.

• Journal of Astronomy and Space Sciences
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• 제37권4호
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• pp.249-255
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• 2020

We develop the tissue-equivalent proportional counter (TEPC) type's space radiation dosimeter to measure in-situ aviation radiation. That was originally developed as a payload of small satellite in the low-earth orbit. This dosimeter is based on a TEPC. It is made of an A-150 tissue-equivalent plastic shell of an internal diameter of 6 cm and a thickness of 0.3 cm. TEPC is filled with pure propane at 13.9 torrs to simulate a cell diameter of 2 ㎛. And the associated portable and low power electronics are also implemented. The verification experiments have been performed by the calibration experiments at ground level and compared with Liulin observation at aircraft altitude during the flight between Incheon airport (ICN) and John F. Kennedy airport (JFK). We found that the TEPC dosimeter can be used as a monitor for space radiation dosimeter at aviation altitude based on the verification with Liulin observation.

• 한국항공운항학회지
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• 제29권1호
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• pp.1-8
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• 2021

Low level wind shear, which often occurs at Jeju International Airport, is a phenomenon that occurs when the topological location and topographical characteristics of Jeju Island are combined with weather characteristics. Low level wind shears, which are caused by rapid changes in wind direction and wind speed, pose a threat to aircraft safety and also cause abnormal situations, such as aircraft go-around, diversion, and cancellation. Many meteorological studies have been conducted on weather patterns, occurrence periods and frequency of low level wind shears. However, researches related to aircraft operations are limited where here we study the similarities and differences between strong southwest winds and bidirectional tailwind type low level wind shears based on aircraft go-around cases at Jeju International Airport. The results are expected to be used to enhance safety when operating to Jeju International Airport, which includes pilot training that reflects the characteristics generated by wind changes, pilot prior notification, providing pilots with latest trends, and increasing extra fuel.

• Nuclear Engineering and Technology
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• 제55권6호
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• pp.2195-2205
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• 2023

One of the salient nuclear fuel performance parameters for new fuel types under development is changes in fuel thickness. To test the new commercially fabricated U-10Mo monolithic plate-type fuel, an irradiation experiment was designed that consisted of multiple mini-plate capsules distributed within the Advanced Test Reactor (ATR) core, the mini-plate 1 (MP-1) experiment. Each capsule contains eight mini-plates that were either fueled or "dummy" plates. Fuel thickness changes within a fuel assembly can be characterized by measuring the gaps between the plates ultrasonically. The channel gap probe (CGP) system is designed to measure the gaps between the plates and will provide information that supports qualification of U-10Mo monolithic fuel. This study will discuss the design and the results from the use of a custom-designed CGP system for characterizing the gaps between mini-plates within the MP-1 capsules. To ensure accurate and repeatable data, acceptance and calibration procedures have been developed. Unfortunately, there is no "gold" standard measurement to compare to CGP measurements. An effort was made to use plate thickness obtained from post-irradiation measurements to derive channel gap estimates for comparison with the CGP characterization.