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Surgical Treatment for Granulosa Cell Tumor in a Thoroughbred Mare (말에서 Granulosa Cell Tumor에 의한 무발정 치료 예)

  • Seo, Jong-Pil;Son, Won-Gyun;Gang, Su-Jin;Kim, Hyung-Jin;Kim, Dae-Yong;Lee, Choung-Seop;Lee, In-Hyung
    • Journal of Veterinary Clinics
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    • v.26 no.5
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    • pp.486-489
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    • 2009
  • An 8-year-old Thoroughbred mare showing anestrus for longer than 6 months with left ovarian mass was referred to Veterinary Medical Teaching Hospital of Seoul National University. For 6 months, the mare had received 2 times hormonal therapies with $PGF_2{\alpha}$ and progesterone. The mare had not responded to these therapies and not shown estrous behavior. On rectal palpation, the left ovary was enlarged and contralateral ovary was small and inactive. Transrectal ultrasonographic examination of the left ovary revealed a mass composed of multiple, irregularly shaped follicles. Granulosa cell tumor (GCT) was suspected according to her history. Ovariectomy was performed through the left flank laparotomy with a standing position in a simple chute located outside of horse farm. The mass was diagnosed as GCT on histopathology. The mare was recovered without any problem and became pregnant next spring.

Investigation of Maximum External Pressure of Helically Coiled Steam Generator Tubes with Axial and Circumferential Through-Wall Cracks (축방향 및 원주방향 관통균열이 존재하는 나선형 전열관의 파손 외압 평가)

  • Lim, Eun-Mo;Huh, Nam-Su;Choi, Shin-Beom;Yu, Je-Yong;Kim, Ji-Ho;Choi, Suhn
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.3_1spc
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    • pp.573-579
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    • 2013
  • Once-through helically coiled steam generator tubes subjected to external pressure are of interest because of their application to advanced small- and medium-sized integral reactors, in which a primary coolant with a relatively higher pressure flows outside the tubes, while secondary water with a relatively lower pressure flows inside the tubes. Another notable point is that the values of the mean radius to thickness ratio of these steam generator tubes are very small, which means that a thick-walled cylinder is employed for these steam generator tubes. In the present paper, the maximum allowable pressure of helically coiled and thick-walled steam generator tubes with through-wall cracks under external pressure is investigated based on a detailed nonlinear three-dimensional finite element analysis. In terms of the crack orientation, either circumferential or axial through-wall cracks are considered. In particular, in order to quantify the effect of the crack location on the maximum external pressure, these cracks are assumed to be located in the intrados, extrados, and flank of helically coiled cylinders. Moreover, an evaluation is also made of how the maximum external pressure is affected by the ovality, which might be inherently induced during the tube coiling process used to fabricate the helically coiled steam generator tubes.

A Case of Herpes Zoster in a 9-month-old Infant (9개월 영아에서 발생한 대상포진 1례)

  • Keun, Seung On;Lee, Soo Young;Kim, Sun Mi;Jeong, Dae Chul;Chung, Seung Yun;Kang, Jin-Han
    • Pediatric Infection and Vaccine
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    • v.9 no.2
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    • pp.230-235
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    • 2002
  • We experienced a case of herpes zoster in a 9-months aged infant as followings; The patient had no history of chickenpox or varicella vaccination. Also, her mother had no history of varicella infection and no contact history with varicella during pregnancy. The patient had only a history of exposure to chickenpox patient at 7th days after birth, but fortunately chickenpox was not developed. Sequentially, symptoms of cough with fever and tachypnea were developed on admission date(7 days had passed already after development of the initial skin lesion). On physical examination, multiple grouped painless erythematous papulovesicles with small crusts were observed on the right lower back, flank and abdomen along the T11 dermatome. Coarse breathing sound was osculated, and increased linear infiltrations on both parahilar areas were seen on chest radiography. Liver enzymes were slightly elevated. Tzanck test was negative. The initial titers of anti-VZV IgM and IgG on admission were negative, but the following titers of anti-VZV IgM and IgG were positive. The patient received treatment of acyclovir for 7 days, and healed completely without sequelae. We report this case with brief review of related literatures.

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Estrogenic Effects of endocrine disruptors and establishment of screening methods in mice (실험동물에서의 환경호르몬 물질의 생체내 영향 및 검색법 정립에 대한 연구)

  • Jung, Ji-Youn;Lee, Yong-Soon
    • Korean Journal of Veterinary Research
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    • v.45 no.4
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    • pp.545-552
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    • 2005
  • The major protocol features of the rodent uterotrophic assay have been evaluated using a range of reference chemicals. The protocol variables considered include the selection of the test species and route of chemical administration, the age of the test animals, the maintenance diet used, and the specificity of the assay for estrogens. The rodents were ovariectomized under general anesthesia via bilateral flank incisions and randomly assigned to groups of 5 animals. Chemicals were DEHP, DBP, BPA and NP, were injected sc once daily with combinations of chemicals treatments for 3 days. In the results, the reported estrogenic chemicals DEHP and DBP were both negative in the single dose treatments. But, in the combinations of chemicals treatments, DEHP and DBP increased in bud number of mammary gland. Treatment of ovariectomized mice with combinations of other chemicals resulted in uterine and vaginal hyperplasia. The additive estrogenic effects were seen with the combinations of $17{\beta}$-Bestradiol and DBP treatment. the competitive estrogenic effects were seen with the combinations of $17{\beta}$-Bestradiol and nonylphenol, $17{\beta}$-Bestradiol and bisphenol-A treatments. These results offers a sysmatic and mechanistically informative approach to assessing estrogenicity. it provides a useful profile of activity using a reasonable amount of resources and is compatible with the study of individual chemicals as well as the investigation of interactions among combinations of chemicals. The results described illustrate the intrinsic complexity of evaluating chemicals for estrogenic activities and conform the need for rigorous attention to experimental design and criteria for assessing estrogenic activity.

Multiple Symmetric Lipomatosis (다발성 대칭성 지방종증 -1례 보고-)

  • Lee, Jo-Han;Hong, Jong-Myeon;An, Jae-Ho
    • Journal of Chest Surgery
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    • v.29 no.2
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    • pp.244-247
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    • 1996
  • Multiple symmetric lipomatosis is a rare disease characterized by progressive growth of subcutaneous fat masses which are located symmetrically at neck, shoulders, chest, abdomen and groin. Recent surveys revealed a high incidence of combined somatic and autonomic neuropathy. The exact cause of the disease is not known. We have experienced one case of multiple symmetric lipomatosis with mediastinal involvement with symptomatic compression of trachea. The patient was a 55-year-male, complaining of dyspnea and slowly enlarging multiple symmetric masses at the neck, shoulders, chest, abdomen, flank and groin over a period of 10 years. He had a habit of excessive alcohol intake for many years. The fatty masses in the neck and the upper mediastinum including peritracheal region were excised through transverse cervical incision. But, because of the incomplete excision of peritracheal fatty tissue, we performed reoperation for the relief of residual tracheal compression at the 15th postoperative day. Two days later emergent tracheostomy was performed due to postoperative pneumomediastinum and subcutaneous emphysema. He could discharge with permanant tracheostomy.

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One-cyclic Volcanic Processes at Udo Crater, Korea (우도(牛島) 분화구(噴火口)에서의 일윤회(一輪廻) 화산과정(火山過程))

  • Hwang, Sang Koo
    • Economic and Environmental Geology
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    • v.26 no.1
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    • pp.55-65
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    • 1993
  • Udo Island, some 3 km off the coast of Sungsan Peninsula at the eastern promontory of Cheju Island, occurs in such a regular pattern on the sequences which reprent an excellent example of an eruptive cycle. The island comprises a horseshoe-shaped tuff cone, a nested cinder cone on the crater floor, and a lava delta which extends over northwest from the moat between two cones. The volcanic sequences suggest volcanic processes that start with emergent Surtseyan eruption, progress through Strombolian eruption and end with lava effusion followed by reworking of smooth tephra on the tuff cone. Eruptive environment and hydrology of vent area in the Udo tuff cone are poorly constrained because the stratigraphic units under the tuff cone are unknown. It is thoughl, however, that the tuff cone could be mainly emergent because the present cone deposits show no evidence of marine reworking, and standing body of sea water could play a great role. The emergent volcano is characterized by distinctive steam-explosivity that results primarily from a bulk interaction between rapidly ascending magma and a highly mobile slurry. The sea water gets into the vent by flooding accross or through the top or breach of tephra cone. Udo tuff cone was constructed from Surtseyan eruption which went into with tephra finger jetting activities in the early stage, late interspersed with continuous uprush activities and proceeded to only continuous uprush activities in the last. When the enclosure of the vent by a long-lived tephra barrier would prevent the flooding and thus allow the vent to dry out, the Surtseyan eruption ceased to transmit into Strombolian activities, which constructed a cinder cone on the crater floor of the tuff cone. The Strombolian eruption ceased when magma in the conduit gradually became depleted in gas. In the case of Udo, the last magmatic activity was Hawaiian-type (and/or fountain) which accumulated basalt lava delta. And then the loose tephra of the tuff cone reworked over the moat lava and the northeastern flank.

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Fine Needle Aspiration Cytology of Retroperitoneal Paraganglioma with an Unusual Pattern - A Case Report - (비전형적인 세침흡인 세포학적 소견을 보인 후복막강 부신경절종 - 1례 보고 -)

  • Kim, Jean-A;Kim, Young-Shin;Kang, Chang-Suk;Lee, An-Hi;Kim, Byung-Kee;Shim, Sang-In;Kim, Sun-Moo
    • The Korean Journal of Cytopathology
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    • v.5 no.1
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    • pp.74-78
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    • 1994
  • A case of retroperitoneal paraganglioma is presented with fine needle aspiration cytologic features. A 57-year-old woman complained of abdominal discomfort and left flank pain for 2 years. The abdominal CT scan revealed an ovoid mass left to the abdominal aorta. Percutaneous fine needle aspiration was performed from the mass. The smear revealed cellular sheets or groups on hemorrhagic background. The tumor cells were ovoid, round to spindle shaped with mild to moderate cellular pleomorphism. The nuclei were round to ovoid and had evenly dispersed chromatin and small nucleoli. The cytoplasm was amphophilic, finely granular and poorly defined. Cells having large or spindle nuclei were quite frequently observed, however, mitosis was not present The cytologic findings suggested paraganglioma, but the frequent spindle cell pattern and the pleomorphism made it difficult to exclude other endocrine tumors and sarcomas. The clinical, histological and ultrastructural findings as well as cytologic findings contributed to confirmatory diagnosis.

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Image Matching Method of Digital Surface Model Generation for Built-up Area (건물지역 수치표면모형 자동생성을 위한 영상정합 방법)

  • 박희주
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.18 no.3
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    • pp.315-322
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    • 2000
  • DSM(Digital Surface Model) is a digital model which represents the surface elevation of a region. DSM is necessary for orthoimage generation, and frequently used in man-made object extraction from aerial photographs nowadays. Image matching technique enables automatic DSM generation. This proposed a image matching method which can be applied to automatic generation of DSM for Built-up Area. The matching method proposed is to find conjugate points and conjugate lines from overlapping aerial images. In detecting conjugate points, the positional relation between possible conjugate point pair as well as correlation of pixel gray value is compared. In detecting conjugate lines, the color attribute of flank region of line, shape of line, positional relation between neighborhood points and lines, and the connection relation between lines are compared. The proposed matching method is assumed to be useful for DSM generation including Built-up Area.

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Thread Rolling Analysis for Lead Screw Process Design (Lead Screw 공정 설계를 위한 전조 해석)

  • Shin, Myoung-Soo;Cha, Sung-Hoon;Kim, Jong-Bong;Kim, Jong-Ho;Ra, Seung-Woo
    • Elastomers and Composites
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    • v.44 no.4
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    • pp.391-396
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    • 2009
  • This paper presents the numerical analysis of thread rolling. Firstly, the analysis is focused on the effective analysis conditions that guarantee the reliability of the analysis results. The investigated parameters are the number of teeth and the number of elements. Using the analysis results, the number of elements and the number of teeth that guarantee the results are found. And then, the effects of the process parameters such as tool shape and temperature on the thread rolling are investigated. The analysis is carried out using DEFORM-3D. The results show that the flank angle and crest round have an effect on the thread rolling load. It is also shown that temperature have significant effects on the effective strain distribution, rolling load, and crack initiation. The crack initiation is predicted using the Cockcroft-Latham criterion.

Tropical Misture Response Derived from Satellite Observations Corresponding to Sea Surface Temperature Anomaly (해수면온도의 ANOMALY에 상응하는 위성관측자료로부터 도출한 열대수증기 RESPONSE)

  • Hyo-Sang Chung
    • International Union of Geodesy and Geophysics Korean Journal of Geophysical Research
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    • v.21 no.1
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    • pp.47-54
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    • 1993
  • The major positive sea surface temperature(SST) anomalies not only occur in the region with the most moisture increase, but also in the flank of the area with sinking motion in the Subtropics. As the large amount of water vapor has been increased by the SST anomaly, the increased of the SST is expected to destabilize the air and leads under moist adiabatic unstable conditions, to an enhanced development of moisture cluster. The 4.0 K change of SST causes the positive difference of Brightness Temperature(TB) of about 10.0k for water vapor channels of TOVS over the north eastern and central tropical Pacific Ocean, but the negative difference of TB of about 7.5 K is shifted southward and southeastward to Southern Pacific Ocean along the equator correspondingly. The difference of the TBs for IR water vapor channel $11(7.3{\mu}m)$ and $12(6.7{\mu}m)$ of TOVS indicative of the moisture distribution during two time periods(January 1983 and 1984), leads us to infer significant changes in the entire tropospheric circulations and the dynamic processes over the Pacific Ocean.

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