• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2022년도 춘계학술발표대회
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• pp.264-267
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• 2022

Recently, federated learning (FL) has increased prominence as a viable approach for enhancing user privacy and data security by allowing collaborative multi-party model learning without exchanging sensitive data. Despite this, most present FL systems still depend on a centralized aggregator to generate a global model by gathering all submitted models from users, which could expose user privacy and the risk of various threats from malicious users. To solve these issues, we suggested a safe FL framework that employs differential privacy to counter membership inference attacks during the collaborative FL model training process and empowers blockchain to replace the centralized aggregator server.

• 한국수산과학회지
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• 제48권3호
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• pp.377-385
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• 2015

The age and growth of the skipjack tuna Katsuwonus pelamis were determined using otoliths sampled from a Korean tuna purse seine fishery in the Western and Central Pacific Ocean from January 2005 to September 2006. A total of 312 otoliths were used to estimate the ages of skipjack tuna, which ranged from 1 to 7 years. The relationships between otolith ring radius (R) and fork length (FL) for female, male, and sex combined were FL = 19.74R + 1.50 ($r^2=0.54$), FL = 17.66R + 6.35 ($r^2=0.47$), and FL = 18.83R + 3.36 ($r^2=0.53$), respectively. The back-calculated fork lengths of each age ($FL_{year}$) were $FL_1=36.2cm$, $FL_2=43.3cm$, $FL_3=48.3cm$, $FL_4=52.6cm$, $FL_5=56.5cm$, $FL_6=60.8cm$, and $FL_7=63.2cm$. The relationships between fork length (FL) and total weight (TW) for female, male, and sex combined were $TW=0.00001FL^{3.19}(r^2=0.95)$, $TW=0.00001FL^{3.17}(r^2=0.95)$, and $TW=0.000009FL^{3.23}(r^2=0.95)$, respectively. The von Bertalanffy growth parameters of skipjack tuna estimated in this study were $L_{\infty}=77.4cm$, K = 0.176/year, and $t_0=-2.569years$.

• 대한화장품학회지
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• 제48권2호
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• pp.105-112
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• 2022

2'-fucosyllactose (2'-FL)는 사람의 모유에 가장 많이 존재하는 올리고당(human milk oligosaccharides, HMOs)으로, 장내 유용 미생물의 성장을 촉진시키고 알레르기, 염증 반응을 완화시키는 것에 도움을 준다. 다양한 긍정적 기능을 가진 2'-FL의 미백 화장품 소재로써의 가능성을 확인하고자, 본 연구를 통해 멜라닌 생성 저해 효능 및 자가포식 유도 가능성을 검토하였다. 인간 유래 멜라닌 생성 세포로 알려진 MNT-1 세포에서 독성 실험을 진행하여 40 g/L 이하에서 세포독성이 없음을 확인하였고, 동일 세포에서 20 g/L 농도로 7 일간 처리하여 멜라닌 생성량을 분석한 결과, 40% 멜라닌 생성 감소를 확인하였다. 멜라닌 생성 관련 인자 TYR 및 TYRP1의 단백질 발현량을 western blot 법을 이용하여 분석한 결과, 2'-FL 처리는 이들을 감소시켰으며, 더불어 자가포식 표지자인 microtubule-associated protein 1 light chain 3 (LC3)의 형태가 LC3-I에서 LC3-𝚷로 변환을 확인할 수 있었다. 공초점 현미경을 통해 2'-FL 처리에 따른 LC3 puncta의 증가가 확인되었다. 따라서, 2'-FL로 활성화된 자가포식이 TYR 및 TYRP1 단백질 발현량을 저해시킴으로서 멜라닌 생성을 감소시키는 것으로 시사된다. 결론적으로 2'-FL은 자가포식을 유도하여 멜라닌 생성이 억제됨이 확인되어 미백 화장품 소재로써의 가능성이 기대된다.

• Nutrition Research and Practice
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• 제18권1호
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• pp.119-131
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• 2024

BACKGROUND/OBJECTIVES: Happiness is an important factor in life, and food literacy (FL) has been emphasized as a core concept for a happy and healthy life. This study examined the level of happiness of Seoul citizens according to their sociodemographic factors and their association with FL. SUBJECTS/METHODS: This study used the data from the Seoul Food Survey, a cross-sectional study conducted on 4,039 Seoul citizens from September to October 2021. FL was measured using a validated questionnaire consisting of 33 items from 3 sub-domains: 14 items in the nutrition and safety domain, 8 items in the cultural and relational domain, and 11 items in the socio-ecological domain. Statistical analysis involved descriptive statistics and multivariate regression analysis. RESULTS: Various sociodemographic factors, such as household income, subjective health status, and food insecurity, were found to be associated with the level of happiness. The level of FL was also associated with the happiness scores. After adjusting for variables associated with happiness, the participants with the highest quartile FL scores were 7.32 times more likely to respond that they were happy than those with the lowest FL score. Three FL domains and total FL showed linear increases in overall happiness after controlling for subjective health status and sociodemographic factors (P < 0.001). CONCLUSIONS: After adjusting for the related covariates, higher levels of FL were associated with higher scores in happiness. Based on this study, it would be meaningful to evaluate ways to intervene in FL to improve the level of happiness among the general population.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제35권2호
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• pp.73-81
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• 2013

Purpose: Smad4 is a central mediator for transforming growth factor-${\beta}$/bone morphogenetic protein ($TGF-{\beta}/BMP$) signals, which are involved in regulating cranial neural crest cell formation, migration, proliferation, and fate determination. Accumulated evidences indicate that $TGF-{\beta}/BMP$ signaling plays key roles in the early tooth morphogenesis. However, their roles in the late tooth formation, such as cellular differentiation and matrix formation are not clearly understood. The objective of this study is to understand the roles of Smad4 in vivo during enamel and dentin formation through tissue-specific inactivation of Smad4. Methods: We generated and analyzed mice with dental epithelium-specific inactivation of the Smad4 gene (K14-Cre:$Smad4^{fl/fl}$) and dental mesenchyme-specific inactivation of Smad4 gene (Osr2Ires-Cre:$Smad4^{fl/fl}$). Results: In the tooth germs of K14-Cre:$Smad4^{fl/fl}$, ameloblast differentiation was not detectable in inner enamel epithelial cells, however, dentin-like structure was formed in dental mesenchymal cells. In the tooth germs of Osr2Ires-Cre:$Smad4^{fl/fl}$ mice, ameloblasts were normally differentiated from inner enamel epithelial cells. Interestingly, we found that bone-like structures, with cellular inclusion, were formed in the dentin region of Osr2Ires-Cre:$Smad4^{fl/fl}$ mice. Conclusion: Taken together, our study demonstrates that Smad4 plays a crucial role in regulating ameloblast and odontoblast differentiation, as well as in regulating epithelial-mesenchymal interactions during tooth development.

• 신재생에너지
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• 제5권1호
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• pp.11-17
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• 2009

To improve the performance of the anode-supported Solid Oxide Fuel Cell (SOFC) which can be operated at an intermediate temperature, the functional layer (FL) is introduced on a anode substrate. And the scandia-stabilized zirconia (ScSZ) and samaria-doped ceria (SDC) which have higher ionic conductivity and better chemical stability than yttria-stabilized zirconia (YSZ) are used as material for the anode FL with the Ni, The fabrication process of anode-supported single cell with the anode FL was established and the power density of those was evaluated. As a result, the sample with anode FL (Ni-YSZ) has higher power density than normal cell. The single cell which was composed of the FL (Ni-YSZ) and electrolyte (YSZ) showed about $550mW/cm^2$ of the maximum power density at $650^{\circ}C$ and $1430mW/cm^2$ at $750^{\circ}C$ respectively, In case of the single cell using the ScSZ and SDC as anode FL, the performance of samples decreased rapidly and those showed unstable voltage during long-term test. In case of using methane as a fuel, the cell performance with each FL decreased comparing with $H_2$ fuel. In the region of a high current density, there are large concentration polarizations.

• 한방재활의학과학회지
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• 제34권1호
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• pp.1-10
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• 2024

Objectives The craniosacral therapy is closely related to the herbal meridians, so we try to explore, compare and develop pharmacopuncture that can have a synergistic effect. Methods The craniosacral pharmacopuncture, Hominis placenta pharmacopuncture, jungseongohhyeol pharmacopuncture, bamboo salt pharmacopuncture 1.8%, bamboo salt pharmacopuncture 3.0%, and normal saline, which are used with craniosacral therapy in clinical practice, were all made and prepared by ourselves. In order to compare antioxidant activity, 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), 2,2-diphenyl-1-picrylhydrazyl, ferric reducing antioxidant powder, total flavonoids, total phenolics methods were all measured. Method validation such as specificity, linearity, precision, and accuracy were performed for craniosacral pharmacopuncture. Results In all antioxidant methods, craniosacral pharmacopuncture showed the highest activity and followed by a Hominis placenta pharmacopuncture. The rest of the pharmacopunctures were measured to have low antioxidant activity. Nodakenin and glycyrrhizin were suitable as index compounds of craniosacral pharmacopuncture and they contained 0.82±0.01 ㎍/mL and 2.56±0.01 ㎍/mL respectively. Conclusions Craniosacral pharmacopuncture has the highest activity in all antioxidant activity experiments, which will help activate craniosacral therapy and quality control is possible through standardized research. Such research will contribute to the development of the oriental medicine industry.

• 대한치과교정학회지
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• 제41권3호
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• pp.184-190
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• 2011

하악 절치부에서 보이는 총생은 하악 절치의 큰 MD/FL (mesiodistal/faciolingual) 인덱스와 관련이 있음이 보고되었다. 큰 MD/FL 인덱스를 보이는 절치에서 치간 삭제를 통해 근원심폭경을 줄여 MD/FL 인덱스를 줄이고 공간을 확보하는 방법이 정당화되기 위해서는 MD/FL 인덱스가 클수록 인접면 법랑질 두께가 더 두꺼워야 할 것이다. 본 연구의 목적은 하악 절치의 MD/FL 인덱스, 근원심폭경, 최대풍융부/치경부폭경비와 같은 치아의 형태적 요인과 인접면 법랑질 두께 사이에 상관관계가 있는지를 조사하는 것이었다. 발거된 하악 절치 40개에서 MD/FL 인덱스, 근원심폭경, 최대풍융부/치경부폭경비를 구하였으며, 근원심폭경을 구한 선상까지 순면을 연마하여 그 단면에서 법랑질 두께를 측정하였다. 치경부근원심폭경은 순면을 연마한 단면에서의 좌우측 백악법랑경계 사이의 폭경을 측정하였다. 이후 법랑질 두께와 MD/FL 인덱스, 근원심폭경, 최대풍융부/치경부폭경비의 상관관계를 조사하였다. 연구결과 하악 절치의 법랑질 두께는 편측에서 $0.75{\pm}0.07mm$였고, 근원심폭경은 $5.56{\pm}0.40mm$였다. 법랑질 두께와 근원심폭경 간에는 유의한 상관관계가 있었지만(R = 0.68), 법랑질 두께와 MD/FL 인덱스, 법랑질 두께와 최대풍융부/치경부폭경비 간에는 상관관계가 없었다. 이는 근원심폭경이 큰 치아에서는 치간 삭제를 더 많이 할 수 있지만, 동일한 근원심폭경을 갖는 절치들의 경우 MD/FL 인덱스가 큰 하악 절치 또는 최대풍융부/치경부폭경비가 커서 삼각형의 형태를 갖는 하악절치에서 치간 삭제를 더 많이 할 수는 없다는 것을 나타낸다.

• 대한지역사회영양학회지
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• 제26권2호
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• pp.77-92
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• 2021

Objectives: Food literacy (FL) can be an important concept that embodies the nutritional capabilities of individuals. The purpose of this study was to introduce the definition and core elements of FL from previous literature, to summarize measurement tools and intervention programs with FL, and to suggest the direction of future research and programs to integrate the concept of FL. Methods: The literature review was conducted through PubMed and Google Scholar databases by combining the search term 'food literacy' with 'definition', 'measurement', 'questionnaire', 'intervention', and 'program'. Among the 94 papers primarily reviewed 31 manuscripts that suited the purpose of the study were used for analyses. Results: There is no consensus on the definition of FL that encompasses the multidimensional aspects of the concept. The definitions of FL were slightly different depending on the authors, and the interpretation of the core elements also varied. Based on the review, we propose a framework of FL that is in line with the current discussion among international researchers. This focuses on the core elements adapted from health literacy, namely functional, interactive, and critical FL. Specifically, we suggest some detailed elements for interactive and critical FL, which were often the subject of divergent views among researchers in previous literature. We found that most of the tools in the reviewed literature provided information on validity and reliability and were developed for a specific target population. Also, most of the tools were focused on functional FL. Similarly, most of the interventions targeted functional FL. Conclusions: This study reviewed the definition and core elements of FL, available measurement tools, and intervention programs using validated tools. We propose the development of tools with sound reliability and validity that encompass the three core elements of FL for different age groups. This will help to understand whether improving food literacy can translate into better nutritional intake and health status among individuals and communities.

• 대한지역사회영양학회지
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• 제28권6호
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• pp.495-508
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• 2023

Objectives: This study aimed to develop a campus-based intervention program to enhance food literacy (FL) among university students. Methods: In the initial phase, we conducted a literature review of FL intervention studies and held in-depth interviews with university students to identify facilitators and barriers to improving and practicing FL. Expert counseling sessions were conducted with nutrition education, marketing, and service design professionals. The results of this phase led to the creation of an initial curriculum draft. In the second phase, a follow-up survey was conducted with young adults to assess the acceptability of the developed curriculum. After the follow-up survey, additional meetings were conducted with the aforementioned experts, and the curriculum was further refined based on their input. Results: An 11-week FL intervention program was devised using constructs from the Social Cognitive Theory. The weekly curriculum consisted of 90-min theory-based and 90-min hands-on experience sessions. Three primary aspects of FL were covered: nutrition and food safety, cultural and relational dimensions, and socio-ecological aspects. Program highlights included cooking sessions for crafting traditional Korean desserts, lectures on animal welfare, insights into zero-waste practices, and communal eating experiences. Based on the study team's previous research, the program also addressed mindful eating, helping participants understand the relationship with their eating habits, and providing strategies to manage negative emotions without resorting to food. Yoga sessions and local farm visits were incorporated into the curriculum to promote holistic well-being. Conclusions: This study elucidated the comprehensive process of creating a campus-based curriculum to enhance FL among university students, a group particularly susceptible to problematic eating behaviors and low FL levels. The developed program can serve as a blueprint for adaptation to other campuses seeking to bolster students' FL.