• Title/Summary/Keyword: Fixed-Effects Model

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Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis

  • Fallahzadeh, Hossein;Jalali, Ali;Momayyezi, Mahdieh;Bazm, Soheila
    • Journal of Gastric Cancer
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    • v.15 no.4
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    • pp.256-261
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    • 2015
  • Purpose: Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer. Materials and Methods: We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software. Results: We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study. Conclusions: The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

Gas Phase Oxidation of Toluene and Ethyl Acetate over Proton and Cobalt Exchanged ZSM-5 Nano Catalysts- Experimental Study and ANN Modeling

  • Hosseini, Seyed Ali;Niaei, Aligholi;Salari, Dariush;Jodaei, Azadeh
    • Bulletin of the Korean Chemical Society
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    • v.31 no.4
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    • pp.808-814
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    • 2010
  • Activities of nanostructure HZSM-5 and Co-ZSM-5 catalysts (with different Co-loading) for catalytic conversion of ethyl acetate and toluene were studied. The catalysts were prepared by wet impregnation method and were characterized by XRD, BET, SEM, TEM and ICP-AES techniques. Catalytic studies were carried out inside a U-shaped fixed bed reactor under atmospheric pressure and different temperatures. Toluene showed lower reactivity than ethyl acetate for conversion on Co-ZSM-5 catalysts. The effect of Co loading on conversion was prominent at temperatures below $400^{\circ}C$ and $450^{\circ}C$ for ethyl acetate and toluene respectively. In a binary mixture of organic compounds, toluene and ethyl acetate showed an inhibition and promotional behaviors respectively, in which the conversion of toluene was decreased at temperatures above $350^{\circ}C$. Inhibition effect of water vapor was negligible at temperatures above $400^{\circ}C$. An artificial neural networks model was developed to predict the conversion efficiency of ethyl acetate on Co-ZSM-5 catalysts based on experimental data. Predicted results showed a good agreement with experimental results. ANN modeling predicted the order of studied variable effects on ethyl acetate conversion, which was as follows: reaction temperature (50%) > ethyl acetate inlet concentration (25.085%) > content of Co loading (24.915%).

The Impact of Innovation Policy Mix on SME R&D Investment: Focusing on Financial Instruments (혁신정책 조합이 중소기업 R&D 투자에 미치는 영향 : 재정지원을 중심으로)

  • Kim, Kiman;Lee, Sooyeon
    • Journal of Convergence for Information Technology
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    • v.10 no.1
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    • pp.1-12
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    • 2020
  • The Government provides a financial assistance to stimulate firm R&D and innovation activities. Previous papers on the impact of public subsidies on firm R&D investments mainly had a focus on an individual policy tool regardless of potential impacts of other policy instruments. This study addresses this gap by examining the effects of policy mix regarding a subsidy and a tax credit. The empirical analyses from fixed effect model using Survey on Technology of SMEs 2015-2017 revealed valuable points. First, policy mix induces more R&D investment of SMEs, which in turn, shows a complementary relationship between two instruments. Second, even if impact of tax credit controlled, subsidy is positively associated with SMEs R&D investment. These findings justify policy mix interventions to promote SME R&D activity. Moreover, grants can be applied as a more useful policy tool for SMEs that are constrained by resources and capabilities.

Free vibration of axially loaded Reddy-Bickford beam on elastic soil using the differential transform method

  • Yesilce, Yusuf;Catal, Seval
    • Structural Engineering and Mechanics
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    • v.31 no.4
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    • pp.453-475
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    • 2009
  • The literature regarding the free vibration analysis of Bernoulli-Euler and Timoshenko beams on elastic soil is plenty, but the free vibration analysis of Reddy-Bickford beams on elastic soil with/without axial force effect using the Differential Transform Method (DTM) has not been investigated by any of the studies in open literature so far. In this study, the free vibration analysis of axially loaded Reddy-Bickford beam on elastic soil is carried out by using DTM. The model has six degrees of freedom at the two ends, one transverse displacement and two rotations, and the end forces are a shear force and two end moments in this study. The governing differential equations of motion of the rectangular beam in free vibration are derived using Hamilton's principle and considering rotatory inertia. Parameters for the relative stiffness, stiffness ratio and nondimensionalized multiplication factor for the axial compressive force are incorporated into the equations of motion in order to investigate their effects on the natural frequencies. At first, the terms are found directly from the analytical solutions of the differential equations that describe the deformations of the cross-section according to the high-order theory. After the analytical solution, an efficient and easy mathematical technique called DTM is used to solve the governing differential equations of the motion. The calculated natural frequencies of one end fixed and the other end simply supported Reddy-Bickford beam on elastic soil using DTM are tabulated in several tables and figures and are compared with the results of the analytical solution where a very good agreement is observed and the mode shapes are presented in graphs.

Chaotic Analysis of Water Balance Equation (물수지 방정식의 카오스적 분석)

  • 이재수
    • Water for future
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    • v.27 no.3
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    • pp.45-54
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    • 1994
  • Basic theory of fractal dimension is introduced and performed for the generated time series using the water balance model. The water balance equation over a large area is analyzed at seasonal time scales. In the generation and modification of mesoscale circulation local recycling of precipitation and dynamic effects of soil moisture are explicitly included. Time delay is incorporated in the analysis. Depending on the parameter values, the system showed different senarios in the evolution such as fixed point, limit cycle, and chaotic types of behavior. The stochastic behavior of the generated time series is due to deterministic chaos which arises from a nonlinear dynamic system with a limited number of equations whose trajectories are highly sensitive to initial conditions. The presence of noise arose from the characterization of the incoming precipitation, destroys the organized structure of the attractor. The existence of the attractor although noise is present is very important to the short-term prediction of the evolution. The implications of this nonlinear dynamics are important for the interpretation and modeling of hydrologic records and phenomena.

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Buffered versus unbuffered local anesthesia for inferior alveolar nerve block injections in children: a systematic review

  • Tirupathi, Sunny Priyatham;Rajasekhar, Srinitya
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.20 no.5
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    • pp.271-279
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    • 2020
  • Background: The present study aimed to evaluate and compare the efficacy of buffered and unbuffered local anesthesia solutions during inferior alveolar nerve block (IANB) administration in children. Methods: PubMed, Ovid SP, and Cochrane databases were searched separately by two independent reviewers for potential papers published between 1980 and April 2020 using relevant MeSH terms and pre-specified inclusion and exclusion criteria. T Studies of IANB administration in children comparing buffered and unbuffered local anesthesia solutions were evaluated. The primary outcome evaluated was pain (perception and reaction), while the secondary outcome was the onset of anesthesia. Results: A total of five articles were included in a qualitative analysis; among them, four qualified for quantitative analysis of the primary outcome and three for quantitative analysis of the secondary outcome. A fixed-effects model was used to perform the meta-analysis. Pain perception (child-reported pain): Significantly lower pain scores were reported with buffered local anesthesia solution than with unbuffered solution (P = 0.006, MD: -0.32, 95% CI: -0.55 to -0.09). Pain reaction (observer-reported pain reaction in child): No significant difference was found between buffered and unbuffered solution in terms of observer-reported pain behavior in the child (P = 0.09, MD: -0.21, 95% CI: -0.46 to 0.04). Onset of anesthesia: A significantly lower duration of anesthesia onset was reported with buffered local anesthesia solution than with unbuffered solution (P = 0.00001, MD: -12.38, 95% CI: -17.64 to -7.13]. Conclusion: Buffering local anesthesia solution may reduce discomfort due to IANB injection administration and lower the initial onset time of anesthesia. More randomized control trials with adequate sample sizes should be carried out to validate the accuracy of these results.

Fast Ambiguity Resolution using Galileo Multiple Frequency Carrier Phase Measurement

  • Ji, Shengyue;Chen, Wu;Zhao, Chunmei;Ding, Xiaoli;Chen, Yongqi
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • v.1
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    • pp.179-184
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    • 2006
  • Rapid and high-precision positioning with a Global Navigation Satellite System (GNSS) is feasible only when very precise carrier-phase observations can be used. There are two kinds of mathematical models for ambiguity resolution. The first one is based on both pseudorange and carrier phase measurements, and the observation equations are of full rank. The second one is only based on carrier phase measurement, which is a rank-defect model. Though the former is more commonly used, the latter has its own advantage, that is, ambiguity resolution will be freed from the effects of pseudorange multipath. Galileo will be operational. One of the important differences between Galileo and current GPS is that Galileo will provide signals in four frequency bands. With more carrier-phase data available, frequency combinations with long equivalent wavelength can be formed, so Galileo will provide more opportunities for fast and reliable ambiguity resolution than current GPS. This paper tries to investigate phase only fast ambiguity resolution performance with four Galileo frequencies for short baseline. Cascading Ambiguity Resolution (CAR) method with selected optimal frequency combinations and LAMBDA method are used and compared. To validate the resolution, two tests are used and compared. The first one is a ratio test. The second one is lower bound success-rate test. The simulation test results show that, with LAMBDA method, whether with ratio test or lower bound success rate validation criteria, ambiguity can be fixed in several seconds, 8 seconds at most even when 1 sigma of carrier phase noise is 12 mm. While with CAR method, at least about half minute is required even when 1 sigma of carrier phase noise is 3 mm. It shows that LAMBDA method performs obviously better than CAR method.

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Influence of Analytical Models on the Seismic Response of Modular Structures (모듈러 구조물의 해석 모델이 지진응답에 미치는 영향)

  • Choi, Kyung-Suk;Lee, Ho-Chan;Kim, Hyung-Joon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.20 no.2
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    • pp.74-85
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    • 2016
  • Seismic design of modular structures is usually carried out under the assumption that their load-carrying mechanism is similar to that of traditional steel moment-resisting frames(SMRFs). However, the load carry mechanism of modular structures would be different with that of traditional SMRFs because of their overlapped structural elements and complicated details of connections for the assembly of the unit-modules. In this study, nonlinear static analyses of 3 and 5-story prototype modular structures have been carried out with four different analytical models, which are established in consideration for the effects of overlapped elements and the hysteretic behavior of connections. Prototype structures present different lateral stiffness and strength depending on the modeling of overlapped elements and the rotational behavior of connections. For modular structures designed under assumption that overlapped structural elements are fully composite each other and connections between unit-modules are fixed, their lateral strength and stiffness can be over-estimated. Furthermore, it is known from the analysis results that modular structures with more than 3-stories would possess relatively low overstrength compared to traditional SMRFs.

THEORETICAL BACKGROUND AND EMPIRICAL EVIDENCE FOR R&D AND ADVERTISING INVESTMENTS IN KOREA (한국기업의 투자 행태 분석 : 이론적 배경과 실증적 근거)

  • 이종일
    • Journal of Technology Innovation
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    • v.3 no.1
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    • pp.185-212
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    • 1995
  • 전통적인 산업조직이론에서 널리 사용되는 시장구조-행동-성과 분석 도구 (The SCP Paradigm)는 시장성과가 가격정책, 기술개발투자(R&D), 광고투자, 생산설비 변경 등 시장행동의 함수라는 암묵적 가정에 근거한다. 최근 시장행동 중에서 기업의 관심이 크게 높아진 R&D 및 광고투자가 시장성과에 미치는 영향이 크게 부각되었으며, 시장성과를 구성하는 주요요인으로 주목받고 있다. R&D 및 광고 투자의 성격과 행태, 그리고 시장성과에 미치는 영향이 상호 유사함에도 불구하고 두 가지 변수를 동시에 다룬 연구는 매우 드물다. 몇 안 되는 연구들도 기업의 행태를 실증적으로 설명하는데 치중함으로써 이론적 근거를 소홀히 하는 경향을 보이고 있다. 즉, 논리의 전개상 이론적인 근거를 바탕으로 수리모형이 먼저 제시된 후에야 이를 검증하는 방법으로 통계모형을 사용하는 것이 옳을 것이다. 이 논문은 기존의 SCP 분석방법을 사용하여 기업이 한정된 재원을 어떤 원칙아래 R&D 및 광고에 분산 투자하는 가를 설명하기 위해 수리모형을 설정한 후, 정태와 동학, 확실성과 불확실성, 단발성과 균등투자전략의 개념을 도입하여 다양한 분석을 시도하였다. 또 R&D 및 광고투자 함수를 이론적 근거에 의해 도입하되, 각 모형에 균형이 존재하는가를 검증하였다. 수리모형을 이용해 분석한 결과 (1) 기업의 투자는 R&D 및 광고투자간에 한계원리(Marginal Principle)가 지켜지도록 분배할 때에 효율적임이 판명되었고, (2) 동학모형이 정학모형을 포함하는 일반모형의 성격을 가지고 있었으며, (3) 투자는 확실성이 높을수록, 분산시킬수록 투자효과가 큰 것으로 나타났다. 한국을 대상으로 한 실증적 모형추정은 앞의 수리모형 및 그 결과에 근거를 두었으며, 한국기업에 적절한 R&D 및 광고투자함수를 추정한 뒤 이를 이용해 업종, 기업규모, 상품유형별로 적합한 모델(Fixed Effects Model)을 결정하고, 각각에 해당하는 통계모형을 구축하였다. 이 결과 (1) 업종 및 기업규모별로 그룹간에 유의한 특성이 발견되었으며, (2) R&D 및 광고투자는 기업의 시장성과를 설명하는 중요한 변수이나, (3) R&D 투자의 경우는 광고에 비해 불확실성이 존재하는 것으로 나타났고, (4) 수리모형에서 도출된 한계원리가 통계모형에서도 유효한 것으로 드러났다.

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A Study on Trim Variation to Reduce the Required Power of 11,000TEU Container Ship in Operation Condition (운항조건에서 11,000TEU 컨테이너선의 소요마력 저감을 위한 트림변화 연구)

  • Lee, Joon-Hyoung;Chun, Jang-Ho;Kim, Myoung-Soo;Park, Beom-Jin;Yu, Yongwan;Lee, Young-Yeon;Ahn, Haeseong;Kim, Youngsun;Lim, Iljin
    • Journal of the Society of Naval Architects of Korea
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    • v.58 no.3
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    • pp.198-205
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    • 2021
  • In this paper, the effect of trim variation on the required power of 11,000TEU container ship was investigated under conditions considering the actual operation speed and draft. For each draft condition, the effective power (PE) and delivered power (PD) trends were investigated with changes in trim and ship speed. At this time, the displacement volume was fixed same as the value of the even trim condition and the both sinkage at the fore and after perpendicular are confirmed. The test ship speeds were determined by considering the operating speed. Both numerical and experimental methods were used to analyze the effects of trim variation. Numerical analysis results were used for evaluating the resistance performance, and the self-propulsion performance was estimated using experimental data obtained from model test.