Journal of Gastric Cancer

The Korean Gastric Cancer Association (대한위암학회)
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Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis

  • Fallahzadeh, Hossein (Research Center of Prevention and Epidemiology of Non-Communicable Disease, Shahid Sadoughi University of Medical Sciences) ;
  • Jalali, Ali (Department of Epidemiology, Faculty of Health, Shahid Sadoughi University of Medical Sciences) ;
  • Momayyezi, Mahdieh (Research Center of Prevention and Epidemiology of Non-Communicable Disease, Shahid Sadoughi University of Medical Sciences) ;
  • Bazm, Soheila (Department of Health Education, Faculty of Health, Shahid Sadoughi University of Medical Sciences)
  • Received : 2015.12.01
  • Accepted : 2015.12.14
  • Published : 2015.12.31
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Abstract

Purpose: Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer. Materials and Methods: We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software. Results: We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study. Conclusions: The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

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References

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