• Journal of Biomedical Engineering Research
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• v.27 no.6
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• pp.392-401
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• 2006

Image Guided Surgery (IGS) system which has variously tried in medical engineering fields is able to give a surgeon objective information of operation process like decision making and surgical planning. This information is displayed through 3D images which are acquired from image modalities like CT and MRI for pre-operation. The technique of image registration is necessary to construct IGS system. Image registration means that 3D model and the object operated by a surgeon are matched on the common frame. Major techniques of registration in IGS system have been used by recognizing fiducial markers placed on the object. However, this method has been criticized due to additional trauma, its invasive protocol inserting fiducial markers in patient's bone and generating noise data when 2D slice images are acquired by image modality because many markers are made of metal. Therefore, this paper developed shape-based registration technique to improve the limitation of fiducial marker based IGS system. Iterative Closest Points (ICP) algorithm was used to match corresponding points and quaternion based rotation and translation transformation using closed form solution applied to find the optimized cost function of transformation. we assumed that this algorithm were used in Total Knee replacement (TKR) operation. Accordingly, we have developed region-based 3D registration technique based on anatomical landmarks and this registration algorithm was evaluated in a femur model. It was found that region-based algorithm can improve the accuracy in 3D registration.

• Journal of the Korea Society of Computer and Information
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• v.12 no.2 s.46
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• pp.123-130
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• 2007

The aim of this study was to propose a fusion and registration method with heterogeneous small animal acquisition system in small animal in-vivo study. After an intravenous injection of $^{18}F$-FDG through tail vain and 60 min delay for uptake, mouse was placed on an acryl plate with fiducial markers that were made for fusion between small animal PET (microPET R4, Concorde Microsystems, Knoxville TN) and Discovery LS CT images. The acquired emission list-mode data was sorted to temporally framed sinograms and reconstructed using FORE rebining and 2D-OSEM algorithms without correction of attenuation and scatter. After PET imaging, CT images were acquired by mean of a clinical PET/CT with high-resolution mode. The microPET and CT images were fusion and co-registered using the fiducial markers and segmented lung region in both data sets to perform a point-based rigid co-registration. This method improves the quantitative accuracy and interpretation of the tracer.

• Radiation Oncology Journal
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• v.37 no.1
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• pp.43-50
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• 2019

Purpose: The aim of this retrospective study was to investigate the use of a radiopaque tissue fiducial marker (TFM) in the treatment of prostate cancer patients who undergo post-prostatectomy radiotherapy (PPRT). TFM safety, its role and benefit in quantifying the set-up uncertainties in patients undergoing PPRT image-guided radiotherapy were assessed. Materials and Methods: A total of 45 consecutive PPRT patients underwent transperineal implantation of TFM at the level of vesicourethral anastomosis in the retrovesical tissue prior to intensity-modulated radiotherapy. Prostate bed motion was calculated by measuring the position of the TFM relative to the pelvic bony anatomy on daily cone-beam computed tomography. The stability and visibility of the TFM were assessed in the initial 10 patients. Results: No postoperative complications were recorded. A total of 3,500 images were analysed. The calculated prostate bed motion for bony landmark matching relative to TFM were 2.25 mm in the left-right, 5.89 mm in the superior-inferior, and 6.59 mm in the anterior-posterior directions. A significant 36% reduction in the mean volume of rectum receiving 70 Gy (rV₇₀) was achieved for a uniform planning target volume (PTV) margin of 7 mm compared with the Australian and New Zealand Faculty of Radiation Oncology Genito-Urinary Group recommended PTV margin of 10 mm. Conclusion: The use of TFM was safe and can potentially eliminate set-up errors associated with bony landmark matching, thereby allowing for tighter PTV margins and a consequent favourable reduction in dose delivered to the bladder and rectum, with potential improvements in toxicities.

• Journal of Digital Convergence
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• v.13 no.1
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• pp.331-339
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• 2015

The purpose of this study is to evaluate utility of rotating adjustment using Xsight spine tracking system in 3D DOF location adjusting method, to minimize error between 6D DOF and 3D DOF in fiducial tracking system. In this study, the result of 6D DOF target location error is $0.124{\pm}0.058mm$, using fiducial inside tumor 3D DOF $0.673{\pm}0.142mm$, outside tumor $1.126{\pm}0.253mm$, apply with Xsight spine tracking system 3D DOF $0.542{\pm}0.103mm$. As the experiment shows, it was demonstrated that rotating adjustment through Xsight spine tracking system is valuable in case of treatment in 3D DOF location error that makes increasing accuracy and dose distribution each approximately 48% and 3%. In accordance with result of this study is useful rotation.

• Journal of the Institute of Electronics and Information Engineers
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• v.54 no.6
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• pp.100-105
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• 2017

This work presents an ECG biometric recognition system for the purpose of biometric authentication. ECG biometric approaches are divided into two major categories, fiducial-based and non-fiducial-based methods. This paper proposes a new non-fiducial framework using discrete cosine transform and a Random Forest classifier. When using DCT, most of the signal information tends to be concentrated in a few low-frequency components. In order to apply feature vector of Random Forest, DCT feature vectors of ECG heartbeats are constructed by using the first 40 DCT coefficients. RF is based on the computation of a large number of decision trees. It is relatively fast, robust and inherently suitable for multi-class problems. Furthermore, it trade-off threshold between admission and rejection of ID inside RF classifier. As a result, proposed method offers 99.9% recognition rates when tested on MIT-BIH NSRDB.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.46 no.3
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• pp.1-9
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• 2009

Using the projected 2-dimensional tilted images obtained from the transmission electron microscopy, we can reconstruct the 3-dimensional structures of objects, such as cells. As a preprocessing procedure, the tilted images should be registered and compensated in terms of the spatial position and the intensity difference, respectively. In this paper, we employ the fiducial marker-based approach to perform a registration, and introduce a simple intensity compensation scheme. Based on the transmissivity image formation model, we propose an algorithm that can compensate the components of the illumination and transmissivity of each image according to the tilted angle. Numerical analysis using real images obtained from the transmission electron microscopy are shown in this paper to show the performance of the proposed algorithm.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.1
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• pp.1-7
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• 2008

PET allows non-invasive, quantitative and repetitive imaging of biological function in living animals. Small animal PET imaging with $[^{18}F]$FDG has been successfully applied to investigation of metabolism, receptor-ligand interactions, gene expression, adoptive cell therapy and somatic gene therapy. Experimental condition of animal handling impacts on the biodistribution of $[^{18}F]$FDG in small animal study. The small animal PET and CT images were registered using the hardware fiducial markers and small animal contour point. Tumor imaging in small animal with small animal $[^{18}F]$FDG PET should be considered fasting, warming, and isoflurane anesthesia level. Registered imaging with small animal PET and CT image could be useful for the detection of tumor. Small animal experimental condition of animal handling and registration method will be of most importance for small lesion detection of metastases tumor model.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.74-79
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• 2009

Fiducial markers have been used frequently in augmented reality applications. However, they represent only ID information to identify a marker, and thus they have limitations when we have multiple types of markers. In this paper, we propose a new marker design for augmented reality applications. We embed a marker’s context, such as type, size, orientation, and ID, in the barcode that has been used just for storing an ID. BY embedding the context information, it is possible to recognize multiple types of markers at once and to render corresponding contents with proper scale. Our marker design can be used in a mobile augmented reality environment where many unknown types of markers may exist.

• Journal of the Korean Society for Precision Engineering
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• v.17 no.3
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• pp.58-67
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• 2000

Electron gun heaters are used to heat a cathode in video(TV) monitors. Major defects of the electron gun heaters include dimensional inaccuracy and pollution with dirty materials. In this paper, to save the labor and time being taken to inspect the heaters, a machine vision system is considered. For the system, a new algorithm is developed to measure the 9 different dimensions of each heater and to detect polluted defects. The algorithm consists of three stages. In the first stage, the center of the heater image is obtained and then its boundary detection is performed. For the efficient boundary detection, a mask called the sum mask is used. In the second stage of the algorithm, a set of fiducial points are determined on the boundary image. Finally, using the fiducial points specified dimensions are measured and the amount of polluted area is computed in the third stage. The performance of the algorithm is evaluated for a set of real specimens. The results indicate that measurements obtained by the algorithm satisfy the tolerance limits fur most of the dimensions and the algorithm detects the polluted defects successfully.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.764-769
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• 2003

The paper introduces a development result for displacement measurement system of multiple moving objects based on image processing technique. The image processing method adopts inertia moment theory for obtaining the centroid of the targets and basic processing algorithms of gray, binary, closing, labeling and etc. To get precise displacement measurement in spite of multiple moving targets, a CCD camera with zoom is used and the position of camera is changed by a pan/tilt system. The fiducial marks on the fixed positions are used as the sensing points for the image processing to recognize the position errors in directions of X -Y coordinates. The precise alignment device is pan /tilt of X - Y type and the pan/tilt is controlled by DC servomotors which are driven by 80c196kc microprocessor based controller. The centers of the fiducial marks are obtained by a inertia moment method. By applying the developed precise position control system for multiple targets, the displacement of multiple moving targets are detected automatically and are stored in the database system in a real time. By using database system and internet, displacement data can be confirmed at a great distance and analyzed. The developed system shows the effectiveness such that it realizes the precision about 0.12mm in the position control of X -Y coordinates.