• Toxicological Research
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• 제11권1호
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• pp.161-168
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• 1995

It has been found that various stress challenges induce the myocardial antioxidant enzymes and produce an acquisition of the cellular resistance to the ischemic injury in animal hearts. Most of the stresses, however, seem to be guite dangerous to an animal's life. In the present study, therefore, we tried to search for safely applicable stress modalities which could lead to the induction of antioxidant enzymes and the production of myocardial tolerance to the ischemia-reperfusion injury. Male Sprague-Dawley rats (200-250 g) were exposed to various non-fatal stress conditions, i.e., hyperthermia (environmental temperature of $42^{\circ}C$ for 30 min, non-anesthetized animal), iramobilization (60 min), treadmill exercise (20 m/min, 30min), swimming (30 min), and hyperbaric oxyflenation (3 atm, 60 min), once a day for 5 days. The activities of myocardial antioxidant enzymes and the ischemia-reperfusion injury of isolated hearts were evaluated at 24 hr after the last application of the stresses. The activities of antioxidant enzymes, superoxide dismutase (SOD), catalase, glutathione peroxidase, glutathione reductase and glucose-6-phosphate dehydrogenase (G6PD), were assayed in the freshly excised ventricular tissues. The ischemia-reperfusion injury was produced by 20 min-global ischemia followed by 30 min-reperfusion using a Langendorff perfusion system. In swimming and hyperbaric oxygenation groups, the activities of SOD and G6PD increased significantly and in the hyperthermia group, the catalase activity was elevated by 63% compared to the control. The percentile recoveries of cardiac function at 30 min of the post-ischemic reperfusion were 55.4%, 73.4%, and 74.2% in swimming, the hyperbaric oxygenation and the hyperthermia groups, respectively. The values were significantly higher than that of the control (38.6%). In additions, left ventricular end-diastolic pressure and lactate dehydrogenase release were significantly reduced in the stress groups. The results suggest that the antioxidant enzymes in the heart could be induced by the apparently safe in vivo-stresses and this may be involved in the myocardial protection from the ischemia-reperfusion injury.

• Journal of Chest Surgery
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• 제40권1호
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• pp.66-68
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• 2007

외상성 심장 손상은 매우 위중한 의학적인 상황이다. 흉벽의 외상이 없는 경우 심장의 손상은 간과될 수 있다. 저자들은 자동차 추돌사고를 입고 우심방 파열이 발생한 47세 여자 환자를 보고한다. 감속손상으로부터 발생하는 비틀림의 힘은 고정점에서 심장의 파열을 일으킬 수 있다. 심장의 심각한 손상을 의심할 수 있는 가장 흔한 증상은 활력증후의 변화이다. 그러므로 감속손상을 입은 환자에서 흉벽의 외상이 없더라도, 이유가 설명되지 않는 저혈압이 관찰될 때 심장의 손상을 의심하여야겠다.

• Journal of Trauma and Injury
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• 제36권4호
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• pp.435-440
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• 2023

Mesenteric injury occurs rarely in cases associated with blunt abdominal trauma. Despite its low incidence, mesenteric injury can lead to fatal outcomes such as hypovolemic shock due to hemoperitoneum or sepsis due to intestinal ischemia, or perforation-related peritonitis. For mesenteric injuries, especially those involving massive bleeding, intestinal ischemia, and perforation, the standard treatment is surgery. However, in the case of operative management, it should be borne in mind that there is a possibility of complications and mortality during and after surgery. The usefulness of transcatheter arterial embolization (TAE) is well known in solid organs but is controversial for mesenteric injury. We present a 75-year-old man with mesenteric injury due to blunt abdominal trauma. Initial abdominal computed tomography showed no hemoperitoneum, but a mesenteric contusion and pseudoaneurysm with a diameter of 17 mm were observed near the origin of the superior mesenteric artery. Since there were no findings requiring emergency surgery such as free air or intestinal ischemia, it was decided to perform nonoperative management with TAE using microcoils in hybrid emergency room system. TAE was performed successfully, and there were no complications such as bleeding, bowel ischemia, or delayed bowel perforation. He was discharged on the 23rd day after admission with percutaneous catheter drainage for drainage of mesenteric hematoma. The authors believe that treatment with TAE for highly selected elderly patients with mesenteric injuries has the positive aspect of minimally invasive management, considering the burden of general anesthesia and the various avoidable intraoperative and postoperative complications.

• Journal of Trauma and Injury
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• 제31권2호
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• pp.72-75
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• 2018

Acetabular and Pelvic ring fractures are major high-energy trauma injuries and are often combined with other injuries. In particular, cause of long duration of immobilization and combined injuries, venous thromboembolism is a common complication in trauma patients with pelvic or acetabular fractures. We report a case of a fatal pulmonary thromboembolism during the acetabulum fracture operation in a 62-year-old male patient.

• Journal of Korean Neurosurgical Society
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• 제65권3호
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• pp.342-347
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• 2022

Head injuries are the most common type of birth injuries. Among them, most of the injuries is limited to the scalp. and the prognosis is good enough to be unnoticed in some cases. Intracranial injuries caused by excessive forces during delivery are rare. However, since some of them can be fatal, it is necessary to suspect it at an early stage and evaluate thoroughly if there are abnormal findings in the patient.

• Journal of Trauma and Injury
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• 제19권2호
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• pp.192-195
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• 2006

Degenerative vascular disease, previous arterial surgery, long-term ureteral stenting, pelvis surgery, and radiotheraphy are reported as causes of artery-to-collecting-system communication.. Artery-to-collecting-system- communication associated with blunt trauma is rare, but potentially fatal. The diagnosis is very difficult and requires a high degree of suspicion. We were able to make the diagnosis based on the characteristic finding of contrast-enhanced computed tomography (CT) obtained in the early phase, equivalent to the finding obtained in the corticomedullary phase of the kidney. We report a case of artery to collecting system communication due to blunt abdominal trauma following a fall, which was treated by embolization.

• 한국자동차공학회논문집
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• 제17권5호
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• pp.133-139
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• 2009

When two cars impact each other, it is usually known smaller vehicle's passenger likely to be more seriously injured than bigger one's. Generally it is known that SUVs and Light Truck Vehicles (LTVs) are bigger and heavier than passenger vehicles and their drive height such as bumper rail and side member, and front end stiffness are higher than those of passenger vehicles. Because of these characteristics the occupants of passenger vehicle struck by SUVs or LTVs are more likely to experience severe injury or fatal injury. To evaluate SUV and LTV's aggressivity to passenger vehicle, SUV to passenger vehicle and LTV to passenger vehicle head-on crash test have been carried out. And finally the way how to reduce incompatibility between SUV and LTV and passenger vehicles is suggested.

• 한국자동차공학회논문집
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• 제15권5호
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• pp.72-77
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• 2007

Since 2000, sports utility vehicles(SUVs) occupy about 40% of domestic vehicle sales. As sports utility vehicle sales are increased the probability of crash accident between SUVs and passenger vehicles increases. Generally, SUVs are heavier than passenger vehicles and their drive height and front end stillness are higher than passenger vehicles. Because of these characteristics SUVs cause more severe injury and fatal injury in SUV to passenger vehicle head-on impact. To evaluate SUV's aggessivity to passenger vehicle, we carried out SUV to passenger vehicle head-on crash test. And finally the way how to reduce incompatibility between SUVs and passenger vehicles is suggested.

• 대한안전경영과학회지
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• 제16권3호
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• pp.273-277
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• 2014

Subcontracting business than the contracting business in shipbuilding industry is a lot of hazardous job and highly accident because of highly work intensity. In order to prevent the accidents, there is a need to analyze characteristic. of shipbuilding, to apply measures of risk assessment. In this paper, I suggested an improvement of the risk assessment through the actual condition research in shipbuilding industry. In the research method, I analysed accidents occurred until 2011-2013. Carried out the actual site survey while two weeks in May 2014. As a result, 1) The main pattern were caught-in or between, fall on the high level according to analyzed accidents. 2) To apply the weight show clear of magnitude for risk assessment. 3) Risk estimation of risk assessment is desirable to be quantization by accidents analysis, and to be greater than or equal to 4 steps.

• Safety and Health at Work
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• 제5권3호
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• pp.158-160
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• 2014

Investigation and analysis of accidents are critical elements of safety management. The over-riding purpose of an organization in carrying out an accident investigation is to prevent similar accidents, as well as seek a general improvement in the management of health and safety. Hundreds of workers have suffered injuries while installing, maintaining, or servicing machinery and equipment due to sudden re-energization of power lines. This study presents and analyzes two electrical accidents (1 fatal injury and 1 serious injury) that occurred because the power supply was reconnected inadvertently or by mistake.