• 한국가족관계학회지
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• 제21권1호
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• pp.29-49
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• 2016

Objectives: The purpose of this study was aimed to examine the effect of self-esteem on life satisfaction and happiness among adolescents, and to verify moderated mediation of peer relations mediated by altruism and self-regulation. Method: The study referred to the 2015 Annual Report of the Korean Children and Youth Panel Survey. More precisely, report on the fourth year research process of the study cohort comprising 2,091 subjects was used to verify the research model. Overall data were analyzed by using SPSS 18.0 program and specifically, moderated mediation were verified by using SPSS Macro, as suggested by Preacher, etc. (2008). Results: As a result, firstly, the peer relations mediated the relationship between life satisfaction and self-esteem among adolescents. Secondly, altruism and self-regulation had moderated mediation effects between self-esteem and peer relations among adolescents. Conclusion: These results suggest that self-esteem affects on life satisfaction and happiness by mediation of peer relations among adolescents and altruism and self-regulation agent is applied positive adjustment to further promote the peer relations and increase life satisfaction among adolescents. Through these study results, the implications for counseling and suggestions for future research were discussed.

• Journal of Chest Surgery
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• 제15권1호
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• pp.67-72
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• 1982

Kartagener`s syndrome is a clinical entity composed of situs inversus, bronchiectasis and chronic sinusitis. This syndrome is rare and is usually detected in childhood. Whether the bronchiectasis in Kartagener`s syndrome is congenital or acquired is still controversial. Some familial cases of this syndrome have been reported, and in these cases the genetic pattern is compatible with an autosomal recessive inheritance with some degree of pleotropism. The authors experienced having 2 cases of Kartagener`s syndrome among 6 siblings in a family. The case No. 1 have had bilateral Caldwell Luc operation, posterior ethmoidectomy, left upper Iobec-tomy with excellent result. The case No. 2 denied to have surgical management.

• 대한수의학회지
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• 제44권1호
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• pp.83-88
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• 2004

Galectin family, endogenous ${\beta}$-galactoside-binding animal lectins, is known for the role in cell differentiation, morphogenesis, apoptosis and tumorigenesis. Galectin-3, one of family member, has been studied for its role in cell differentiation and tumor metastasis, and for its expression on epithelial cells of colon and mast cells but not in brain. Several reports, however, suggest its expression in brain including as a prion binding protein. In this report we explored possibility of galectin-3 expression in brain tissue. With Western blot and RT-PCR with rat brain tissues, we could detect galectin-3 that was not shown by conventional immunohistochemistry. Our results indicated galectin-3 was expressed in brain, and substantiate the previous report on galecin-3 as a prion-related protein in brain.

• Biotechnology and Bioprocess Engineering:BBE
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• 제7권3호
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• pp.155-162
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• 2002

The cyclic amidohydrolase family enzymes, which include allantoinase, dihydroorotase, dihydropyrimidinase and (phenyl)hydantoinase, are metal-dependent hydrolases and play a crucial role in the metabolism of purine and pyrimidine in vivo. Each enzyme has been independently characterized, and thus well documented, but studies on the higher structural traits shared by members of this enzyme family are rare due to the lack of comparative study. Here, we report upon the expression in E. coli cells of maltose-binding protein (MBP)- and glutathione S-transferase (GST)-fused cyclic amidohydrolase family enzymes, facilitating also for both simple purification and high-level expression. Interestingly, the native quaternary structure of each enzyme was maintained even when fused with MBP and GST. We also found that in fusion proteins the favorable biochemical properties of family enzymes such as, their optimal pHs, specific activities and kinetic properties were conserved compared to the native enzymes. In addition, MBP-fused enzymes showed remarkable folding ability in-vitro. Our findings, therefore, suggest that a previously unrecognized trait of this family, namely the ability to functional fusion with some other protein but yet to retain innate properties, is conserved. We described here the structural and evolutionary implications of the properties in this family enzyme.

• 대한간호학회지
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• 제43권6호
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• pp.812-820
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• 2013

Purpose: The purpose of this study was to construct a structural equational model to explain and predict burnout in family caregivers of patients with cancer. The study was based on the Stress-Appraisal-Coping Model of Lazarus and Folkman (1984) and Family Stress Theory (Hill, 1958). Methods: Data were collected from July 10 to September 30, 2012 through direct interviews and a self -report questionnaire survey. Participants in this study were 206 family caregivers providing care for patients with cancer in In-patient or Out-patient departments of three different general hospitals located in Busan. Measured variables were exogenous variables (social support and perceived health status) and endogenous variables (perceived stress, hope and burnout). Results: Goodness of fit in the hypothetical model was ${\chi}^2=174.07$, TLI=.95, CFI=.97, RMSEA=.08. Perceived health status, perceived stress, and hope showed statistically significant direct effects on burnout of family caregivers. Social support affected burnout of family caregivers indirectly. These variables explained 68.5% of total variance in burnout. Conclusion: The results from this study suggest that perceived stress, perceived health status, and hope should be considered as major influential factors when developing nursing interventions to control burnout of family caregivers (of patients with cancer).

• Child Health Nursing Research
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• 제11권3호
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• pp.322-329
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• 2005

Purpose: This study was done to investigate satisfaction with life in adolescents, and to identify factors affecting satisfaction with lift for adolescents. Method: The participants were 540 adolescents. Data were collected through self-report questionnaires which were constructed to include satisfaction with life, mental health, family adaptability and cohesion, and school adjustment. The data were analyzed using the SPSS program. Results: Satisfaction with life in adolescents correlated with mental health, family adaptability and cohesion, and school adjustment. Satisfaction with lift in adolescents was significantly different according to scholastic achievement, parents being alive, economic level of family, and types of family cohesion and adaptability. Significant predictors influencing satisfaction with life in adolescents were school adjustment, family cohesion, mental health, and economic level of family, and these predictors accounted for $28.3\%$ of the variance in satisfaction with lift. Conclusion: The above findings indicate that satisfaction with life in adolescents is influenced by mental health, family function, and school adjustment. Therefore when nursing interventions are developed to improve satisfaction with life in adolescents, these factors need to be considered.

• Perspectives in Nursing Science
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• 제14권1호
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• pp.21-31
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• 2017

Purpose: This study was conducted to identify the disease adaptation and related factors for the pediatric patients with diabetes mellitus. Methods: Participants in this study were 75 diabetic children or adolescent whose age were 10 to 18 years old visited the out-patient clinic in one general hospital located in Seoul. Data were collected using self-report questionnaires. Research tools measuring resilience, family support, psychological adaptation, Hemoglobin A1c (HbA1c) protein were used. Results: Resilience showed significant differences according to the age, gender, academic achievement, and hospitalization experience of the children. Family support was significantly different according to the age, religion, academic achievement, fathers' education level, and hospitalization experience of the children. Psychological adaptation to diabetes showed significant differences according to academic achievement. HbA1c was shown to be significant difference according to fathers' education level and hospitalization experience of the children. Positive correlations were identified among resilience, family support, and psychosocial adaptation, while negative correlations were found between HbA1c and all others including resilience, family support, and psychosocial adaptation. Conclusion: This study suggests that the educational programs as nursing intervention needs to be developed to enhance the resilience and family support for the pediatric diabetic patients.

• 지역사회간호학회지
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• 제24권4호
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• pp.480-487
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• 2013

Purpose: The purpose of this study was to investigate the relationship among family functioning, empathy and aggression by high school students. Methods: This was a descriptive study. The survey participants were 467 high school students from M city. Data were collected from November 29 to December 7, 2012 and self-report questionnaires including a Family Adaptability Cohesion Evaluation Scale, Interpersonal Reactivity Indexes, and an Aggression Questionnaire. The collected data were analyzed by descriptive statistics, independent-samples t-test, ANOVA, stepwise multiple regression. Results: The majority of the subjects were 2nd graders (42.0%) and female (57.2%). 59.7% of the subjects had religion, 84.8% were living together with parents. The mean ages of their fathers and mothers were $49.90{\pm}0.20$ and $46.85{\pm}0.19$ respectively. Aggression was found to have a statistically negative correlation with family functioning and empathy. Stepwise multiple regression analysis revealed that the most powerful predictor of aggression was empathic concern. Empathic concern, family cohesiveness, perspective taking, personal distress and gender accounted for 16.7% of the variances. Conclusion: It is necessary to provide aggressiveness reduction programs for high school students that consider their family functioning and empathy.

• 한국보건간호학회지
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• 제34권3호
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• pp.405-415
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• 2020

Purpose: This study was undertaken to identify the mediating effect of family strengths in the relationship between e-learning readiness and learning management system-based online education learning outcomes. Our results provide basic data for proposing strategies to increase online education learning outcomes of nursing students. Methods: A self-report questionnaire was surveyed by 133 nursing students who took online education using a learning management system at three nursing colleges in Daejeon, Jeonbuk, and Gyeongbuk. The mediating effect of family strengths in the relationship between the e-learning readiness of the subject and online education learning outcomes, were analyzed by hierarchical multiple regression. Sobel test was performed to verify effectiveness of the pathway. Results: In the relationship between e-learning readiness and online education learning outcomes of nursing students, family strengths were determined to exert absolute mediating effect. Conclusions: Our results indicate that in order to improve e-learning readiness, the basic curriculum for nursing students should include web-based communication, cooperation, and the use of information technology, including interaction for online education. Improvements in family strengths can be achieved through home study activities, such as frequent conversations with members, monitoring achievements of the students, and sharing family leisure activities.

• Human Ecology Research
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• 제61권2호
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• pp.183-194
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• 2023

The purpose of this study was to examine how sociodemographic status, family-related influences, and perceived future economic prospects were associated with the possibility of getting married and having children in a sample of 607 single young Korean adults. The sample comprised unmarried men and women in their 20s and 30s taken from the 2021 Seoul Family Report survey, and descriptive statistical and multiple regression analyses were conducted on the data. The results indicated that age, non-traditional marriage/childbearing values, parents' marital relationship during childhood, and the prospect of having a stable job and owning a home were significantly related to the possibility of marriage. With regard to the possibility of having children, a significant relationship was found with age, level of education, non-traditional marriage/childbearing values, recognition of the importance of family, parents' marital relationship during childhood, and the prospect of having a stable job and owning a home. The study also examined the importance of policies that make the possibility of marriage and having children more appealing to young unmarried adults in Korea by providing a positive outlook for the economy, a sense of stability, and a supportive approach to the value of having a family.