• BMB Reports
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• 제39권5호
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• pp.595-606
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• 2006

Metallothioneins are a group of low molecular mass and cysteine-rich metal-binding proteins, ubiquitously found in most living organisms. They play an important role in maintaining intracellular metal homeostasis, eliminating metal toxification and protecting against intracellular oxidative damages. Analysis of complete rice genome sequences revealed eleven genes encoding putative metallothionein (OsMT), indicating that OsMTs constitute a small gene family in rice. Expression profiling revealed that each member of the OsMT gene family differs not only in sequence but also in their tissue expression patterns, suggesting that these isoforms may have different functions they perform in specific tissues. On the basis of OsMT structural and phylogenetic analysis, the OsMT family was classified as two classes and class I was subdivided into four types. Additionally, in this paper we also present a complete overview of this family, describing the gene structure, genome localization, upstream regulatory element, and exon/intron organization of each member in order to provide valuable insight into this OsMT gene family.

• Asian-Australasian Journal of Animal Sciences
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• 제20권8호
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• pp.1169-1173
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• 2007

The protein encoded by SLC27A2 gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family, and it converts free long-chain fatty acids into fatty acyl-CoA esters, and thereby plays a key role in lipid biosynthesis and fatty acid degradation. In the present study, SLC27A2 located on human chromosome 15 was selected as candidate gene and we isolated and cloned partial fragments of mRNA sequence and genomic fragments of porcine SLC27A2 gene. The coding region of the gene as determined by alignments shared 90% and 82% identity with human and mouse cDNAs, respectively. Detection in LargeWhite and Meishan breeds showed that a single nucleotide polymorphism (SNP) ($A{\rightarrow}G$) existed in exon 7, which caused corresponding amino acid changed for encoding. In LargeWhite pigs it encoded for Val while in Meishan pigs it encoded for Ile, so we developed the PCR-RFLP genotype method for detection of this polymorphism. Association study in 135 $F_2$ reference family indicated that significant correlation existed between the polymorphism and growth and carcass traits.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제34권1호
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• pp.4-14
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• 2023

This study aimed to discuss mental health services for children and adolescents that are being implemented as initiatives of the Korean government and to review the functions and roles of these projects during the COVID-19 pandemic. Three government departments are in charge of providing mental health services for children and adolescents: Ministry of Education, Ministry of Gender Equality and Family, and Ministry of Health and Welfare. The Ministry of Education has implemented several policies to facilitate the early detection of mental health issues among school students (from preventive interventions to selective interventions for high-risk students). The Ministry of Gender Equality and Family additionally serves out-of-school children and adolescents by facilitating early identification of adolescents in crises and providing temporary protection or emergency assistance (as required) through the Community Youth Safety-Net Project. Furthermore, the Ministry of Health and Welfare operates relevant mental health agencies for individuals of all ages including children and adolescents. Any high-risk students who have been screened through the projects of the Ministry of Education are supported through referrals to the following institutions for appropriate treatment of their symptoms: specialized hospitals, the Youth Counseling and Welfare Center operated by the Ministry of Gender Equality and Family, the National Youth Healing Center, the Mental Health Welfare Center operated by the Ministry of Health and Welfare, the Suicide Prevention Center, and the Child Welfare Center. To assist students who are facing any psychological difficulties because of the COVID-19 pandemic, the Ministry of Education has established a psychiatric support group for providing emergency mental health care; furthermore, schools are promoting psychological surveillance (e.g., provision of non-face-to-face counseling services that are centered around the Wee Center). The Ministry of Education, Ministry of Gender Equality and Family, and Ministry of Health and Welfare have provided varied mental health support services in order to address the challenges faced by children and adolescents during the pandemic. Nevertheless, the mental health services operated by each ministry do show some limitations because their service provision system is insufficiently collaborative. The present study discussed the positive effects of each initiative as well as its limitations; furthermore, it suggested improvements for facilitating the healthy development of children and adolescents' mental health.

• 보건교육건강증진학회지
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• 제26권1호
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• pp.159-170
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• 2009

The purpose of this study was to review national mental health policy goal in Korea and America, and to suggest strategies for advancing the national mental health policy in Korea. Objectives: First, the review of nation mental health policy in Korea. Second, the review of nation mental health policy in America. Third, the development of nation mental health plan in Korea. Methods: To achieve this objectives, review the books, journals, and national published papers and so on. Results: First, 15 goals are planned for mental health promotion in Korea Health Plan 2010. Second, 14 goals and multiple strategies are planned for mental health promotion in America Healthy People 2010. Third, 3 plans are suggested for mental health promotion in Korea. Conclusion: Mental Health is essential dimension in holistic health. And mental health promotion has been increasingly emphasized in national health plan. Therefore, effective nation mental health policy establishment would be needed continuously.

• 식물분류학회지
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• 제52권3호
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• pp.173-183
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• 2022

Through the collection of herbarium specimens in Bhutan over the years, new plant species are discovered nearly annually. Thus, this paper reports two new genera and 19 new records of flowering plant species from Bhutan. The new genera include Eurycorymbus of the family Sapindaceae and Homalium of the family Salicaceae. The new records of plant species are Eranthemum erythrochilum (Acanthaceae), Hemidesmus indicus (Apocynaceae), Ilex umbellulata (Aquifoliaceae), Canarium strictum (Burseraceae), Ehretia acuminate (Boraginaceae), Vaccinium sikkimense (Ericaceae), Nothapodytes foetida (Icacinaceae), Machilus edulis (Lauraceae), Grewia asiatica (Malvaceae), Hibiscus fragrans (Malvaceae), Cipadessa baccifera (Meliaceae), Baccaurea javanica (Phyllanthaceae), Canthiumera glabra (Rubiaceae), Homalium napaulense (Salicaceae), Eurycorymbus cavaleriei (Sapindaceae), Acmella radicans (Asteraceae), Silene latifolia (Caryophyllaceae), Cleome rutidosperma (Cleomaceae), and Cuphea carthagenensis (Lythraceae). Morphological determinations of the genera and species were carried out at the National Herbarium (THIM) of the National Biodiversity Centre of Bhutan. Brief descriptions of the species, phenology, and photo plates are provided in this annotated checklist.

• 기독교교육논총
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• 제64권
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• pp.173-202
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• 2020

본 연구는 교회 가정사역 프로그램 참여자의 학습참여동기가 서번트 리더십에 미치는 영향과 공동체 의식의 구조적 관계를 탐색하기 위해서 수행되었다. 먼저 선행연구 분석을 통해 구조모형을 구성하였다. 구조모형 검증을 위해 전국의 교회 및 단체에서 실시하는 교회 가정사역에 프로그램에 참여하고 있는 부부를 대상으로 배포한 설문지 700부 중 607부를 대상 자료로 수집하였다. 자료수집은 교회 가정사역 이후 학습참여동기, 서번트 리더십, 공동체 의식을 설문지를 사용하여 수집하였다. 수집된 자료는 구조방정식 모형 분석 방법을 사용하여 학습참여동기에 대한 서번트 리더십의 영향과 공동체 의식의의 구조적 관계에 대해 분석하였다. 그 결과 본 연구에서 제안한 구조적 모형이 타당한 것으로 검증되었다. 이에 학습참여 동기 가운데 내재적 동기와 외재적 동기의 영향을 공동체 의식이 매개하여 서번트 리더십에 영향을 주는 것으로 검증되었으며, 서번트 리더십의 영향을 공동체 의식이 매개하는 경로가 영향력을 가지고 있는 것으로 검증되었다. 이에 교회 가정사역을 운영할 때, 참여자들의 내재적 참여동기와 외재적 참여동기를 고려하여 공동체 의식을 조절한다면 학습참여동기의 수준을 조절할 수 있다는 시사점을 제시할 수 있다.

• 한국의료질향상학회지
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• 제14권1호
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• pp.61-68
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• 2008

• 재활간호학회지
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• 제7권2호
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• pp.220-230
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• 2004

Purpose: The study has planned to find out the perceived social support of the families with pneumoconiosis patients. Method: The subjects of the study were the 300 family care givers of the pneumoconiosis patients who were hospitalized in Taeback, Donghae and Jeongsun Occupational Medical Center. The Social Support Survey Instrument developed by Park(1985) was adopted. Results: The Direct Perceived Supports showed statistically differences by the age(F=1.70 p=0.01) and the state of the disease(F=3.09 p=0.027) of the patients. The Health Situation Centered Support was different by the marietal situation(F=2.29 p=0.48) of the pneumoconiosis patients. The Indirect Perceived Supports were statistically different by sex(t=3.76 p=0.043) and relation with the patient (F=2.49 p=0.048), group joining(t=3.79 p=0.042) of the family care givers. The DPSs were statistically different by family income(F=2.25 p=0.025), family authority(F=2.81 p=0.031) and health insurance status(F=2.13 p=0.026). Recommendation: It is recommended to develop an active social support program at the pneumoconiosis care centers for the middle aged female family care givers of the pneumoconiosis patients with the support of Ministry of Labor, Ministry of Health and Welfare and other NGOs of pneumoconiosis.

• Journal of Microbiology and Biotechnology
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• 제26권4호
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• pp.730-738
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• 2016

est19 is a gene from Bacillus sp. K91 that encodes a new esterase. A comparison of the amino acid sequence showed that Est19 has typical Ser-Gly-Asn-His (SGNH) family motifs and could be grouped into the SGNH hydrolase family. The Est19 protein was functionally cloned, and expressed and purified from Escherichia coli BL21(DE3). The enzyme activity was optimal at 60℃ and pH 9.0, and displayed esterase activity towards esters with short-chain acyl esters (C₂-C₆). A structural model of Est19 was constructed using phospholipase A1 from Streptomyces albidoflavus NA297 as a template. The structure showed an α/β-hydrolase fold and indicated the presence of the typical catalytic triad Ser49-Asp227-His230, which were further investigated by site-directed mutagenesis. To the best of our knowledge, Est19 is a new member of the SGNH hydrolase family identified from thermophiles, which may be applicable in the industrial production of semisynthetic β-lactam antibiotics after modification.

• 가족자원경영과 정책
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• 제18권2호
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• pp.17-35
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• 2014

This study analyzes the transition of the Family-Friendly Index from 2007 to 2012. This index was developed using a questionnaire survey that is distributed to listed companies and public institutions every year by the Ministry of Gender Equality & Family(MOGEF) and the Family-Friendly Support Center. The Family-Friendly Index contains an introduction to and the practical use of family-friendly regulations and programs, such as flexible working systems, parental leave, family leave, EAP, and family-friendly culture. The number of companies involved in the Family-Friendly Index is increasing every year, and has increased from 41.7 in 2007 to 58.9 in 2012. In particular, family-friendly companies testimonialized by the MOGEF are using more family-friendly programs than other company.