• 한국임상수의학회지
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• 제25권4호
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• pp.236-240
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• 2008

부갑상샘 호르몬 (PTH)은 칼슘과 무기인의 수송을 조절한다. 속발성 부갑상샘 기능항진증은 대개 만성신부전에서 발생하고, 이는 개와 고양이에 있어서 CRF의 일반적인 합병증이다. 신부전을 갖는 21마리의 개가 본 연구에 사용되었다. 공시동물로부터 채혈한 혈액 중 칼슘 (Ca),무기인 (iP), PTH의 농도를 측정하여 칼슘과 무기인의 비율에 따라 두 군으로 분류하였다 (Ca / iP $\leq$ I; 그룹 1, Ca/ip $\geq$ 1.5; 그룹 II). 성과 연령 사이에 부갑상샘 호르몬 수준은 유의성 있는 차이가 없었다. 두 군 사이에 부갑상샘 호르몬 수준과 Ca/P의 비율에는 유의성 (p<0.0001)있는 차이가 나타났다. 결론적으로, 칼슘과 무기인의 비율은 신부전을 갖는 개에서 부갑상샘 호르몬 수준을 예측하기 위한 지표로 이용될 수 있을 것으로 생각된다.

• 한국지반공학회논문집
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• 제36권4호
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• pp.5-15
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• 2020

본 논문은 점성토의 응력-변형률 관계를 모사하기 위해 한계 상태 이론을 기반으로 하여 수정한 Modified Cam-Clay 파괴면을 제안한다. 평균유효응력과 von Mises 응력의 공간에서 타원형상의 파괴면을 가지는 Modified Cam-Clay 모델의 경우, 강성 및 발달법칙 미적용시, 비배수 전단조건하에 한계상태 평균유효응력은 선행압밀 평균유효응력의 절반이 되며, 이는 실제 점성토의 거동과 차이가 있다. 본 연구에서는 선행압밀 평균유효응력은 점성토의 압밀이력으로 정량화되고, 한계상태 평균유효응력은 점성토의 현재 간극비로 산정되어, 이 둘간의 비율이 고정되지 않는 찌그러진 형태의 파괴면을 제안한다. 제안된 파괴면을 항복평면으로 가정하고, 비배수 삼축압축 거동을 모사한 결과, 실내 실험 결과와 유사한 결과를 얻을 수 있었다

• Geomechanics and Engineering
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• 제36권5호
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• pp.417-426
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• 2024

Shield tunneling method is widely used to build tunnels in complex geological environment. Stability control of tunnel face is the key to the safety of projects. To improve the excavation efficiency or perform equipment maintenance, the excavation chamber sometimes is not fully filled with support medium, which can reduce the load and increase tunneling speed while easily lead to ground collapse. Due to the high risk of the face failure under non-fully support mode, the tunnel face stability should be carefully evaluated. Whether compressive air is required for compensation and how much air pressure should be provided need to be determined accurately. Based on the upper bound theorem of limit analysis, a non-fully support rotational failure model is developed in this study. The failure mechanism of the model is verified by numerical simulation. It shows that increasing the density of supporting medium could significantly improve the stability of tunnel face while the increase of tunnel diameter would be unfavorable for the face stability. The critical support ratio is used to evaluate the face failure under the nonfully support mode, which could be an important index to determine whether the specific unsupported height could be allowed during shield tunneling. To avoid of face failure under the non-fully support mode, several charts are provided for the assessment of compressed air pressure, which could help engineers to determine the required air pressure for face stability.

• Korean Circulation Journal
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• 제52권12호
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• pp.878-886
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• 2022

Background and Objectives: Moderate aortic stenosis (AS) confers a surprisingly adverse prognosis, approaching that of severe AS. The objective of this study was to describe the clinical course of patients with moderate AS with evidence of concomitant heart failure manifesting as elevated brain natriuretic peptide (BNP) levels. Methods: This is a single-center, retrospective cohort study of 332 patients with elevated BNP. 165 patients with moderate AS were compared with 167 controls with none-mild AS. The Median follow-up duration was 3.85 years. The primary outcome was a composite endpoint of all-cause hospitalizations and all-cause mortality. Results: BNP levels were 530 and 515 pg/mL in the study and the control groups, respectively. Moderate AS had significantly higher rates of primary composite endpoint in both univariate analysis (hazard ratio [HR], 1.50; 95% confidence interval [CI], 1.14-1.97; p=0.004) and adjusted analysis (HR, 1.45; 95% CI, 1.05-2.01; p=0.02). Moderate AS had 1.41 (95% CI, 1.18-1.69; p<0.001) times more all-cause hospitalization per patient-year of follow-up compared to controls in the univariate model. After adjustment for significant covariates, moderate AS remained an independent predictor of all-cause hospitalizations (incidence rate ratio [IRR], 1.45; 95% CI, 1.18-1.79; p=0.005). Furthermore, moderate AS was significantly associated with higher all-cause hospitalization rates in both heart failure with reduced ejection fraction (IRR, 1.33; 95% CI, 1.02-1.75; p=0.038) and heart failure with preserved ejection fraction [IRR], 1.31; 95% CI, 1.03-1.67; p=0.026). Conclusions: Moderate AS in conjunction with elevated BNP portends a significantly worse prognosis than those without moderate AS and should be followed closely.

• Tribology and Lubricants
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• 제7권1호
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• pp.16-27
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• 1991

The mechanism of failure of lubricated surfaces at high sliding speeds was investigated. Experiments were performed with the ball-on-flat and cylinder-on-flat geometries, using lubricants of four different chemical reactivities. Surface failure was found to not be predictable using the ratio, $\lambda$, of fluid film thickness to composite surface roughness except when chemically inert lubricants are used. Even then the influence of temperature rise on fluid film thickness does not adequately explain the low load carrying capacity of lubricants at high sliding speeds, which causes surface failure. The protective layers on sliding surfaces that form by chemical reaction with the lubricant were found to reduce the surface roughening and increase the load carrying capacity of surfaces to values of $\lambda$ as low as 0.03. Neither the surface roughening nor the formation of the protective layers have been incorporated into failure models for lubricated systems.

• Journal of Chest Surgery
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• 제28권9호
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• pp.842-846
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• 1995

Recently, the trauma patients have been markedly increasing due to the vast increase of traffic accident, industrial disaster, incidental accident and violence. The authors have analysed of 22 patients of thoracic injuries combined with abdominal injuries and summarized as follows. The ratio of male to female was 3.4:1 and their age distribution was from 5 years to 68 years and mean age was 34.4 years. The etiologies of injury were traffic accident, stab wound, fall down and violence. Associated injuries were fractures, bowel perforation, kidney rupture, head injury, liver laceration, spleen rupture and so forth. The modes of treatment were closed thoracostomy, repair of diaphragm, ruptured bowel repair, explo-thoracotomy, splenectomy, hepatic lobectomy in this order of frequency. The postoperative complications were atelectasis, wound infection, pneumonia, empyema, acute renal failure, respiratory failure and bleeding. The mortality rate was 13.6% [3/22 and the causes of death were respiratory failure 1 case, acute renal failure 1 case and hypovolemic shock 1 case.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 봄 학술발표회 논문집(I)
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• pp.691-696
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• 1999

This paper is aimed to investigate flexural rehabilitation effect o pre-loaded reinforced concrete beams strengthened by carbon fiber sheet. Main Test parameters are reinforcement ratio and the magnitude of pro-loading and seven test beams are analyzed rehabilitation effect by carbon fiber sheet, load-deflection, failure mode, stress of reinforcing bar by the magnitude of pre-loading. Test results show that internal force was showed pre-loaded specimens lower than no-loaded specimens during rehabilitation and changing stiffness was showed in the same was and failure mode showed brittle failure from all specimens.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1988년도 한국자동제어학술회의논문집(국제학술편); 한국전력공사연수원, 서울; 21-22 Oct. 1988
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• pp.1055-1058
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• 1988

A systematic way of failure diagnosis in a linear system with decentralized estimators is developed. The generalized likelihood ratio (G.L.R) approach to failure detection and identification is used for designing a diagnosis system in each subsystem based on the innovation analysis. For the simplicity of the theoretical formulation, a design scheme of failure diagnosis is developed for the system decomposed into two subsystems. To demonstrate the effectiveness of our approach, several simulation studies have been carried out on a third-order linear system which is constructed of a second-order damped oscillator and a first-order lag.

• International Journal of Reliability and Applications
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• 제12권1호
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• pp.61-77
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• 2011

One of the most important problems in the estimation of the parameter of the failure model, is the cost of experimental sampling units, which can be reduced by using any prior information available about ${\theta}$, and devising a two-stage pooling shrunken estimation procedure. We have proposed an estimator of the reliability function (R(t)) of the exponential model using two-stage time censored data when a prior value about the unknown parameter (${\theta}$) is available from the past. To compare the performance of the proposed estimator with the classical estimator, computer intensive calculations for bias, mean squared error, relative efficiency, expected sample size and percentage of the overall sample size saved expressions, were done for varying the constants involved in the proposed estimator (${\tilde{R}}$(t)).

• 한국생산제조학회지
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• 제19권6호
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• pp.804-811
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• 2010

The fatigue crack propagation is stochastic in nature, because the variables affecting the fatigue behavior are random and have uncertainty. Therefore, the fatigue life prediction is critical for the design and the maintenance of many structural components. In this study, fatigue experiments are conducted on the specimens of magnesium alloy AZ31 under various conditions such as thickness of specimen, the load ratio and the loading condition. The probability distribution fit to the fatigue failure life are investigated through a probability plot paper by these conditions. The probabilities of failure at various conditions are also estimated. The fatigue design life is predicted by using the Weibull distribution.