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Relationship between Calcium/Inorganic Phosphorus and Parathyroid Hormone Concentrations in Dogs with Renal Failure  

Kang, Dong-Joon (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Lee, Soo-Han (Department of Clinical Pharmacology and Therapeutics, Asan Medical Center, University of Ulsan College of Medicine)
Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Chung, Byung-Hyun (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University)
Publication Information
Journal of Veterinary Clinics / v.25, no.4, 2008 , pp. 236-240 More about this Journal
Abstract
Parathyroid hormone (PTH) regulates calcium (Ca) and phosphate transport. Secondary hyperparathyroidism usually occur in chronic renal failure (CRF), and it is a common complication of CRF in dogs and cats. Twenty one dogs with renal failure were enrolled in this study. Plasma Ca, inorganic phosphorus (iP) and PTH concentrations were measured. Dogs were divided into two groups by the ratio of Ca to iP (Ca/iP$\leq$1; Group I, Ca/iP$\leq$1.5; Group II). The PTH level between sexes ages were not significantly different. The PTH level and Ca/iP between two groups were significantly different (p < 0.0001). In conclusion, The ratio of Ca to iP may be considered as useful surrogator to predict PTH level of dogs with renal failure.
Keywords
Ca; inorganic phosphorus; parathyroid hormone; renal failure; dogs;
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